Polysorb MP, powder for the preparation of suspension for oral administration, 12 g, 1 pc.

In this article we will look at the side effects of Polysorb. This drug is a universal active sorbent with the properties of an antacid medication. This drug binds a variety of pathogenic microorganisms and toxic substances as they pass through the digestive system (stomach and intestines). This product is universal, as it is capable of binding and removing microbial toxins, metabolic products, food allergens, medications, poisons, etc. from the human body.

“Polysorb” is now increasingly prescribed for cleansing the body. At the moment, the pharmacological drug has a large sorption capacity, due to which it can bind several times more harmful substances in comparison with aluminum-magnesium silicates (for example, Smecta), methylsilicic acids (Sorbolong, Enterosgel, Atoxil) ), lignins (“Lignosorb”, “Polyphepan”, “Liferan”) and activated carbon. Taking this into account, the scope of use of this medication is quite wide. Since it effectively relieves intoxication of any nature, it can be used as part of a complex treatment of any pathology, including dermatoses, influenza, allergies, various infections, etc.

Many people are interested in whether Polysorb has side effects, but we’ll talk about that later.

Release form, composition

It is produced in one dosage form - powder for suspension for oral administration. For ease of use, this powder is packaged in plastic jars of 50, 25 and 12 g and double-layer bags of 3 g (single dosage for an adult). Such packaging options help to purchase the optimal volume of the medicine. The product "Polysorb" contains colloidal silicon dioxide as an active (sorbing) chemical element. It contains no other components. Externally, this medication has the appearance of a white powder with a slight bluish tint. The product has no smell. When the powder is dissolved in water, a white suspension is observed. Cleansing with Polysorb should be carried out according to the instructions and recommendations of the doctor.

Therapeutic effect

This product is a group of sorbents of inorganic origin. According to its basic properties, the drug does not have a selective effect, that is, it is capable of sorbing different classes of substances. Due to this nonspecific activity, as well as increased sorption capacity, the drug "Polysorb" has the following therapeutic properties:

• sorption;
• detoxifying.

The detoxifying effect of this medication is due to its main property of binding a wide variety of substances, including toxic ones, and removing them. The basis of detoxification using this product is its sorption effect. The sorbent binds chemicals that entered the body from the outside (exogenous) and were formed directly in it (endogenous). The medicine is able to effectively remove pathogenic microorganisms (viruses, bacteria, fungi), toxins that these pathogenic microorganisms secrete, foreign antigens, medicinal substances, food allergens, poisons, radionuclides, metal salts, ethyl alcohol and its breakdown products. In addition to the above toxic substances, Polysorb binds metabolic products formed in the body. Often, an excess of such products leads to the development of various symptoms of intoxication and pathological processes in the form of diseases.

In addition, Polysorb removes endogenous compounds such as bilirubin, cholesterol, urea, lipid complexes, as well as substances that can cause the development of endotoxicosis. The versatility of the ability to bind toxins allows the use of this medication to eliminate intoxications of almost any etiology - from food poisoning to severe pathological conditions. This sorbent is considered an excellent remedy that is present in combination therapy for many diseases.

The use of this product can significantly reduce the volume of other pharmacological drugs that are necessary for the quality treatment of many diseases. In developed countries, it is considered necessary to use Polysorb even for flu or colds, since this remedy eliminates the unpleasant symptoms of intoxication (muscle pain, apathy, weakness, dizziness).

Physiological basis of enterosorption

The mechanisms of the therapeutic effect of the enterosorption method with Polysorb MP are associated with both direct and indirect effects. Mass exchange with the sorbent involves saliva, gastric juice, bile, pancreatic juice, jejunal and ileal juice, of which 1 is released per day, respectively; 2; 0.5; 1; 2; 0.5 liters. Already in the stomach there is a uniform distribution of Polysorb MP in the liquid phase of the secretion and food components, with which the drug enters the duodenum. The stage of sorption in the stomach in an acidic environment is very important, since the sorbent is not saturated and has the maximum ability to bind toxic products. In the small intestine, sorption of both substances taken peros and components of the secretion of the mucous membrane, liver and pancreas occurs. With prolonged administration of Polysorb MP in the small intestine, per 1 g of the drug there is an average of 100 ml of chyme. The area of ​​contact with chyme is inversely proportional to the size of the sorbent particles. So for Polysorb MP it is 300 m2/g. As the enterosorbent moves through the intestines, the ratio between the amount of drug and chyme increases due to the concentration of intestinal contents and is 1:2-1:4 in the terminal colon. The concentration of intestinal contents improves sorption conditions, although the sorption capacity of the drug is moderately reduced. Components passing from the vascular bed into the interstitium, and then into the intestinal lumen through the glandular apparatus, reach the glycocalyx trans- or paracellularly and are transported in the mucous layer mainly due to diffusion. In the intestinal lumen, transport of substances to the sorbent occurs through facilitated diffusion along a concentration gradient and due to convective flows supported by intestinal peristalsis. In cases where the layer of mucous deposits is continuous, contact of the sorbent and the epithelium does not occur. Starting from the duodenum, the sorption process occurs in an alkaline environment. Polysorb MP binds some digestive enzymes and hydrolysis products. In the small intestine, sorption of a large list of biologically active substances (BAS) that enter the lumen with intestinal juices and bile (regulatory peptides, prostaglandins, serotonin, histamine, etc.) is possible. The rate of penetration of biologically active substances into the intestinal lumen is about 0.3% of the total activity in 1 minute. Sorption of microbial cells and their toxins begins from the part of the gastrointestinal tract where bacterial colonization begins. Primary sorption effects are accompanied by secondary positive reactions. Thus, the sorption of toxins and the prevention of their absorption reduces the metabolic load on other organs of detoxification and excretion, and helps improve the humoral environment and immune status. The binding of gases during putrefactive fermentation makes it possible to eliminate flatulence and improve blood supply to the intestines during the process of enterosorption. Moving through the gastrointestinal tract, Polysorb MP, due to irritation of receptor zones, is able to enhance motility and evacuation of intestinal contents. As is known, food intake improves tissue perfusion of the intestine by one and a half to two times, enhances motility and oxygen consumption by tissues in all parts of the gastrointestinal tract. Overbloating of the intestines with gases leads to a block of microcirculation and inhibition of metabolic processes. A starvation diet reduces motility and the evacuation of putrefactive foods. The stimulating mechanism of Polysorb MP was noted in acute and chronic intoxication of the gastrointestinal tract. The list of direct and indirect mechanisms of the therapeutic effect of Polysorb MP is much longer than in the above section. Of course, this method of efferent therapy affects the function of all organs and systems, as evidenced by the various clinical effects in the treatment of patients with various pathological processes. Enterosorption Polysorb MP is used in medicine for the treatment of acute and chronic diseases accompanied by toxicosis , digestive disorders, immune status, lipid metabolism, bile acids and other types of metabolism. Every year, the indications for the use of Polysorb MP are expanding, and its enteral use makes it possible to eliminate or reduce the intensity of drug therapy, including antibiotics, hormones, and desensitizing drugs. Currently, the importance of enterosorption in nutritionists and diet therapy is gradually increasing. Polysorb MP is capable of binding many types of xenobiotics, the number of which already amounts to millions, and adsorbing radioactive elements and salts of heavy metals. If initially sorbents were used mainly for the treatment of dyspepsia and poisoning , now the scope of use of the drugs has expanded significantly. For many pathological processes, enterosorption has become the main method of treatment, against which other methods of pharmaco- and efferent treatment are used. First of all, this can be attributed to the treatment of atherosclerosis and chronic diseases. There has been a certain transformation of views when comparing enterosorption with other methods of efferent therapy (primarily hemosorption). With the accumulation of experience in extracorporeal detoxification, the negative aspects of invasive treatment methods associated with the need for heparinization, traumatization of blood cells, and technical complications of perfusion became more and more obvious. These circumstances encourage more frequent preference for non-invasive methods. The main mechanisms of the therapeutic action of Polysorb MP.

Enterosorption with Polysorb MP
Direct action	Indirect action
sorption of poisons and xenobiotics ingested orally	prevention and mitigation of toxic-allergic reactions
sorption of poisons secreted by the secretions of mucous membranes, liver, pancreas	prevention of the somatogenic stage of endotoxemia
sorption of endogenous secretion and hydrolysis products	reducing the metabolic load on natural detoxification organs
sorption of biologically active substances (neuropeptides, serotonin, prostaglandins, histamine, etc.)	correction of metabolic processes and immune status
sorption of pathogenic bacteria and their toxins	improving the state of the body’s humoral environment, eliminating the imbalance of biologically active substances
gas binding	restoration of the integrity and permeability of membranes
irritation of receptor zones of the gastrointestinal tract	eliminating flatulence and improving blood supply to the intestines
stimulation of intestinal motility

Indications for use

The list of main indications for the use of the drug "Polysorb" includes the following pathological conditions:

• intoxication in adults and children in acute or chronic form of any etiology, regardless of the reasons for its development;
• acute intestinal infections caused by a variety of pathogenic microorganisms;
• food poisoning;
• dysbacteriosis;
• various inflammatory and purulent pathologies that provoke the development of severe intoxications (for example, adnexitis, appendicitis, purulent wounds, burns, etc.);
• acute poisoning with potent substances and poisons (for example, medications, alcohol, alkaloids, heavy metals, and so on);
• allergic reaction to food - all types of allergies, in particular hay fever.
• high concentration of bilirubin due to the development of jaundice or viral hepatitis;
• increased levels of nitrogenous products in the body (creatinine, urea, uric acid) with chronic renal failure;
• for preventive purposes for people who work in chemical production or live in areas with unfavorable environmental conditions.

In many developed countries, it is customary to use Polysorb for colds. In addition, this sorbent is successfully used in the complex therapy of various dermatological diseases, such as psoriasis, eczema, dermatitis, acne, etc.

We will consider the contraindications and side effects of Polysorb below.

Should I take the drug for weight loss?

Polysorb is definitely not worth considering as a panacea. Moreover, the manufacturer himself does not recommend using the product for more than 14 days in a row.

If you ignore this advice, you can get:

• decreased activity of the gastrointestinal tract;
• intestinal dysfunction: constipation, diarrhea;
• deficiency of nutrients and vitamins.

However, the main problem is not even disruption of the body’s functioning, but the formation of a certain type of behavior. Psychologists say that a person gains excess weight due to many years of cultivating bad habits - overeating at night and an inactive lifestyle.

Enterosorbents help people...cultivate bad habits, nothing more. By filling your stomach with something inedible, first of all, you are deceiving yourself. After all, real weight loss requires reformatting your relationship with food. You will have to feel hungry for some time, reducing the portions of what you eat.

Method of administration and dosage regimen

This pharmacological agent should be taken orally in the form of an aqueous suspension. To prepare it, you need to dissolve the powder in 50–100 ml of water, drink the resulting liquid quickly, without waiting for a suspension to form. Adults take the medication in a volume of 100–200 mg per 1 kg of weight (6 to 12 g of medication). The maximum daily dosage of the medication is no more than 20 g, which must be divided into several doses. "Polysorb" is taken an hour before or after meals. If the sorbent is used to relieve food allergies, it must be taken before or during food consumption.

The duration of the therapeutic course of this medication is determined by the severity of the pathological process and the speed of stabilization of the patient's condition. For example, when treating acute intoxication (alcohol or food poisoning), it is enough to take the drug for 3–5 days. When treating allergic diseases (dermatitis) or chronic intoxication (for example, renal failure, hepatitis, etc.), a course of treatment lasting 14 days is necessary. In this case, therapy must be repeated every 2–3 weeks. The interval between courses of taking the sorbent cannot be less than 14 days.

Not everyone knows how Polysorb is useful for the body, so we’ll talk about it in the following sections.

How to use Polysorb correctly for weight loss

Those who use this product for weight loss are advised to adhere to the following rules:

• The powder must be diluted taking into account body weight. Dosage – 2 grams of powder per 10 kilograms. It is easy to dilute bagged sachets, which are packaged in 1 gram quantities.
• The daily dose should be divided into three doses. Before use, be sure to dilute the powder, because using it in dry form can cause digestive problems. Take 20 minutes before meals.
• Use only freshly prepared suspension.
• Do not use for more than 2 weeks. It is assumed that the desired effect will be achieved during this time. Then side effects will begin to appear.

Please note that the drug does not have a fat burning effect. Its actions include the ability to help digest food, remove toxins, and cleanse toxins. At the same time, it is advised to improve eating behavior and build a sports regimen. Then fat burning will start. If you do not follow these two rules, then the course of using enterosorbent will not bring the expected results. The question arises: is Polysorb even needed in a weight loss system?

The medicine helps with acute poisoning

With this pathology, it is necessary to remove as many toxins and poisons as possible from the body. To do this, you should perform a gastric lavage using a suspension of the drug "Polysorb", after which another 6 g of this drug is taken orally in several doses. The medication should be taken with tea, water or Regidron solution in order to replenish lost fluid. If the poisoning is severe, then gastric lavage must be repeated after 4–7 hours. On the second day of treatment for food infection, the medicine is taken 4 times a day, 3 g and, depending on the patient’s condition, therapy is canceled or extended for another 5 days.

How to take it to cleanse the body?

The easiest way to carry out a comprehensive cleansing of the body for an adult is by mixing a tablespoon of powder in half a glass of water. Children usually receive tea at their reception. If necessary, the amount is recalculated: for example, the daily dose for adults is 0.1-0.2 g per kg of body weight. Prepare a suspension three times a day and drink it an hour before meals or the same period of time after. The duration of the course is a week, but you can extend the cleansing up to 14 days.

1 g of Polysorb is placed in a heaped teaspoon, and up to 3 g in a tablespoon.

From the instructions for the drug you can find out when to use Polysorb for a hangover, how to take it, dosage and treatment features. To bind as many harmful substances as possible, on the first day the drug should be drunk 5 times every hour, on the second day - 4 times at the same interval. Additionally, you should drink the maximum amount of fluid to return the volume of circulating blood to normal.

Using the powder you can avoid a hangover or at least reduce its manifestations. To do this, drink a dose of the suspension before a holiday or other occasion for drinking alcohol. The second portion of Polysorb should be taken in the evening, before bedtime, and the product should be diluted a third time after waking up.

The drug is useful for intestinal infectious diseases

On the first day of development of an intestinal infection, the drug is taken 3 g (tablespoon) every hour. In total you need to use five such dosages. On the second day of therapy, the dose is 3 g 4 times a day. If after such treatment the patient’s condition returns to normal, you can stop taking the medication. If the intoxication cannot be removed completely, the course of therapy with this sorbent is extended for another two days.

Polysorb for weight loss: pros and cons

The weight loss system based on the intake of enterosorbent has its supporters and opponents. Judging by numerous reviews on the Internet, many people were lucky: they were able to lose weight with the help of the drug up to 8 kilograms in a month. However, there is one big “but”. They were completely healthy and at the same time adhered to proper nutrition and physical activity.

It is important to understand that if you use Polysorb for a long time, it can remove harmful and beneficial substances. Endocrinologists do not advise reducing the size of the stomach and losing weight with the help of Polysorb. It would be wiser if you introduce foods rich in plant fiber into your diet. With their help, you can cleanse the intestinal tract and establish a balanced diet, allowing the extra pounds to go away on their own.

Acute allergic reactions

Drug or food allergies begin to be treated with gastric and intestinal lavage with a suspension of this drug. To prepare it, you need to dissolve 10 g of powder in 1 liter of liquid. The intestines are washed with an enema. After the above procedures, the sorbent is taken orally for 5 days, 3 g 4 times a day. For chronic food allergies, longer use of this drug is required - up to 14 days, 3 g four times a day. In this case, the suspension should be drunk immediately before meals. Urticaria, eosinophilia, hay fever, atopic dermatitis and other diseases of an allergic nature are also treated.

Is Polysorb always allowed to cleanse the body?

Contraindications

Like any medicine, Polysorb has a number of contraindications for which it is better to refrain from taking it:

• bleeding of the gastrointestinal tract;
• acute phase of stomach ulcer;
• pregnancy period;
• breast-feeding;
• intestinal atony;
• children's age up to 12 years.

Using the drug in the presence of contraindications may not bring benefit, but quite a lot of harm. In order not to harm your health, you should first consult a doctor, and only then start using the drug.

Side effects of the drug

This drug is usually well tolerated by patients and causes virtually no side effects. In extremely rare cases, against the background of the high absorption capacity of the elements present in its composition, the medication can provoke the development of constipation and disruption of the movement of feces through the intestines. In addition, it is very rare that children may develop an allergic reaction to the drug. If you take it correctly according to the instructions, then the risk of side effects from Polysorb will be minimal.

Advantages and disadvantages

Positive sides:

• Polysorb is superior to activated carbon in its main parameters. One dissolved sachet replaces 120 tablets.
• Helps reduce the side effects of overeating.
• Improves the condition of the skin.

Negative sides:

• Overdose leads to constipation and allergies.
• Do not use for more than 14 days due to the risk of impaired nutrient absorption.
• The drug may reduce the therapeutic effect of other drugs.

Analogs

Today, the medical product has the following analogues on the Russian pharmacological market:

• "Diosmectite";
• "Microcel";
• "Smecta";
• "Neosmectin"
• "Enterodesis";
• "Enterosorb";
• "Enterumin";
• "Lactofiltrum";
• "Polyphepan";
• "Entegnin";
• "Lignosorb";
• "Enterosgel";
• Activated carbon.

Reviews of cleansing with Polysorb

Most of the reviews about the drug are positive. This assessment of the drug is due to its high effectiveness in relieving various types of intoxications. Patients note that such a sorbent helps to quickly eliminate skin rashes that arise due to insufficient liver function, or when digestive processes are disrupted due to various diseases of the gastrointestinal tract. Moreover, many patients appreciated the effectiveness of this drug in the treatment of allergic reactions, food and intestinal infections, colds, flu, etc. The sorption properties of the drug, according to information from reviews, are successfully used by surgeons to clean purulent wounds and ulcers.

Side effects from Polysorb in adults and children are extremely rare. The first note the good effect of the drug in treating hangover syndrome and preventing the consequences of overeating. Separately, we can note positive reviews from pregnant women who used this medication to reduce the symptoms of toxicosis.

Many people purchase this medicine for their children in adolescence to combat acne and purulent pimples. Parents of such teenagers say that the rashes have become less frequent and are gradually disappearing.

We reviewed the instructions and side effects of Polysorb in children and adults.

Expert opinion

The main goal of manufacturers of any drug is to sell as many products as possible. The creators of Polysorb are no exception. This medication should be used strictly according to indications after face-to-face consultation with a specialist.

Weight loss cannot be achieved by consuming Polysorb and doing nothing else for it. Obesity develops over the years and under the influence of a bunch of factors: heredity, unbalanced diet, inactive lifestyle, metabolic disorders. No drug can cure such a problem in two weeks.

In addition, Polysorb has serious side effects and contraindications. Excessive use will lead to metabolic disorders, edema, anemia, increased appetite and unpleasant disruptions in the intestinal tract.

The number of people who want to lose weight with the help of a magic remedy does not cease to increase. The reason for the rapid popularity around this product is its ease of use. Everyone wants to quickly and easily get rid of hated kilograms by swallowing a magic pill. There is a glimmer of hope for improved skin, getting rid of pimples, blackheads, extra folds and centimeters. We are all adults, but we never stop believing in miracles. Looking for a universal magic wand to cure all ills, we forget that it does not exist. Just like there is no technique that will help alone.