Rhinonorm


Composition of Rinonorma

Depending on the type of nasal spray Rinonorm, the composition is 10 ml. of this medicine may contain either 5 mg. (for children) or 10 mg. (for adults) the active substance xylometazoline hydrochloride .
In addition, the preparation contains such auxiliary compounds as: 85% glycerol , citric acid monohydrate, sodium citrate dihydrate, as well as water intended for injection.

Nasal drops Rinonorm

The nasal drug Rinonorm is a vasoconstrictor that clears secretions from the nasal passages within a short period of time after use. In addition, swelling of the nasal mucosa disappears. This effect of the product ensures full breathing, but due to the active substance, complications may arise with prolonged use, and you will become dependent on the drops. To avoid such problems, you must read the instructions for use of the drug, studying the composition, contraindications and method of use.

Compound

Depending on the type of spray (adult or child), the amount of the active component varies:

  • For adults. The active substance is xylometazoline hydrochloride 10 mg. Auxiliary components include citric acid monohydrate, water for injection, glycerol 85%, sodium citrate dihydrate.
  • For children. The active ingredient is half as much - 5 mg, and the excipients remain unchanged.

Release form

Rinonorm nasal drops are available in the form of a clear solution without a specific color of 0.05% and 0.1%. The liquid is packaged in bottles with a volume of 15 ml, made of dark glass with a special spray nozzle for convenient injection of the drug into the nasal passages and a protective cap. The bottles themselves are placed in cardboard packaging, where the name and basic information are indicated.

Pharmacodynamics and pharmacokinetics

The nasal drug is actively practiced by ENT doctors for local use. The spray is an alpha-adrenergic agonist due to the active substance xylometazoline hydrochloride. Due to this, the arterioles narrow, which has a positive effect on the nasal mucosa, reduces swelling, and eliminates hyperemia. When used topically, the active substance is absorbed into the bloodstream in a minimal amount.

Rinonorm spray reduces the amount of secretion in the nasopharynx a couple of minutes after use. This effect lasts for 6-8 hours after local application. There is a resumption of obstruction in the nasal passages, sinus openings and Eustachian tubes. This ensures an improvement in the patient’s health and the absence of complications from secretion stagnation.

Indications for use

According to the instructions for use of the drug, the indications for use are as follows:

  • preparing patients for nasopharyngeal diagnosis;
  • acute sinusitis;
  • exacerbation of chronic sinusitis;
  • improvement of the mucous membrane in acute otitis media in combination with rhinitis;
  • acute allergic rhinitis;
  • viral, bacterial acute rhinitis.

Contraindications

Before using the product, you must familiarize yourself with the list of contraindications for the drugs that are listed below:

  • high sensitivity and allergy to individual components of nasal drops;
  • atrophic rhinitis with inflammation of the nasal mucosa, skin, and crust formation;
  • previous hypophysectomy;
  • children under 2 years of age with a spray for children;
  • children under 10 years of age with a spray for adults;
  • use of MAO inhibitors (monoamine oxidase);
  • taking antidepressants;
  • angle-closure glaucoma;
  • atherosclerosis;
  • thyrotoxicosis
  • prostatic hyperplasia.

The product should be used with caution if you have the following health problems:

  • arterial hypertension;
  • severe diseases of the cardiovascular system;
  • hyperthyroidism;
  • diabetes.

Pharmacodynamics and pharmacokinetics

This nasal spray is actively used for topical use in the practice of ENT doctors. the xylometazoline contained in the drops is an alpha-adrenergic agonist, this active compound helps to constrict arterioles , which has a beneficial effect on the nasopharyngeal mucosa by reducing swelling and eliminating hyperemia.

Rinonorm helps reduce the amount of secretions within a few seconds after topical application. The medicinal effect of the drops lasts for several more hours. The medicine restores the patency of the nasal passages, Eustachian tubes, and also the openings of the sinuses.

Under the influence of nasal drops, the well-being of patients significantly improves by restoring the air patency of the nasopharynx , and also reduces the likelihood of developing complications that inevitably arise with prolonged stagnation of secretions.

Pharmacological properties

Rinonorm is characterized by a clearly expressed anti-congestive effect on the human body.

Pharmacodynamics

The active component of the drug, xylometazoline, is an adrenergic agonist that promotes constriction of arterioles. This has a beneficial effect on the condition of the mucous membranes of the nasopharynx, reducing swelling and eliminating hyperemia. Rinonorm improves the patency of the Eustachian tubes, sinus openings and nasal passages, and also reduces the risk of complications associated with prolonged stagnation of secretions.

Pharmacokinetics

When Rinonorm is applied topically, the amount of secretion in the nasopharynx decreases within a few seconds after xylometazoline enters the body. The effect of the drug lasts for another 3-4 hours.

Indications for use

Rinonorm is indicated for use in the therapeutic treatment of rhinitis (allergic, bacterial or viral), sinusitis (in acute or chronic acute phases), as well as to eliminate swelling of the mucous membranes of the Eustachian tube in otitis media . In addition, drops are used as a preparatory agent before carrying out diagnostic manipulations in the nasal passages.

special instructions

If you decide to make your breathing easier by using Rinonorm nasal spray, don't worry about the manageability. The product has no effect on driving or regulating other mechanisms. This property distinguishes it from some analogues. Taking Rinonorm should not be long-term, especially for patients with chronic rhinitis. This is due to the fact that the drops can cause constant nasal congestion up to atrophy of the mucous membrane.

During pregnancy and breastfeeding

Most experts say that taking Rinonorm drops is contraindicated for girls during pregnancy and lactation. The active substance of the nasal spray is xylometazoline, which narrows not only the vessels in the nasal passages, but also the arteries of the placenta. This helps reduce the supply of nutrients to the fetus. Rinonorm during pregnancy can be used only in extreme cases and after consulting a doctor.

Contraindications Rinonorma

Absolute contraindications for Rinonorm include the following cases:

  • dry or atrophic rhinitis;
  • angle-closure glaucoma;
  • patient age under 2 years;
  • hypersensitivity to the main and auxiliary components of the drug compound.

It is not recommended to use these nasal drops in conditions following hypophysectomy , as well as when taking tricyclic antidepressants and MAO inhibitors ( monoamine oxidase ).

Contraindications

  • Children under 2 years of age - for 0.05% spray, up to 10 years - for 0.1% spray;
  • Atrophic (dry) rhinitis;
  • Conditions after hypophysectomy;
  • Angle-closure glaucoma;
  • Concomitant use of tricyclic antidepressants or monoamine oxidase inhibitors;
  • Pregnancy;
  • Hypersensitivity to any component of Rinonorm.

Carefully:

  • Lactation period;
  • Diabetes;
  • Hyperthyroidism;
  • Severe heart disease;
  • Arterial hypertension;
  • Concomitant use of bromocriptine.

Side effects

Quite rarely, however, the following side effects may occur:

  • increased excitability;
  • headache;
  • increased blood pressure;
  • arrhythmia;
  • insomnia;
  • nausea;
  • irritation of mucous membranes;
  • burning or itching;
  • skin rashes.

Rinonorm, instructions for use (Method and dosage)

Instructions for use of Rinonorm differ depending on the type of drops. A children's spray containing a 0.05% xylometazoline solution is prescribed one dose (equivalent to one press of the dispenser - 0.14 ml) into each nostril no more than three times a day.

For adult patients, as well as children over the age of 10 years, a drug containing 0.1% xylometazoline is prescribed in a dosage equal to one press on the piston device in each nostril no more than three times a day.

The total duration of use of the medicine should not exceed seven days. It is advisable to maintain a six-hour interval between the use of drops. To enhance the effectiveness of the spray, it is worth clearing the nasal sinuses of secretions before using it.

Analogs

Rinonorm has similar drugs in terms of mode of action, effect or active ingredient. Information about analogues of the product is contained in the following table.

Name Description Manufacturer Release form Dosage Percentage of active substance content Price, rub.
Galazolin Vasoconstrictor drug for local use. The action begins within 10 minutes and lasts for 5-6 hours. The active substance is xylometazoline. Warsaw Polfa plant, Poland drops 10 ml 0.05% 35
0.1% 41
gel 10 g 0.05% 126
0.1% 157
Grippostad Reno Reduces swelling and hyperemia of the nasal mucosa without disturbing the function of the ciliated epithelium of the mucous membrane, 5 minutes after use. The effect lasts up to 10 hours. The active substance is xylometazoline. STADA, Germany drops for adults 10 ml 0.1% 91
drops for children 10 ml 0.05% 20
For the nose A vasoconstrictor to relieve symptoms of rhinitis. The effect occurs in a couple of minutes and lasts 10 hours. The active ingredient is xylometazoline. Sandoz Private Limited, India spray 10 ml 0.1% 96
drops 10 ml 0.05% 74
Novartis, Switzerland spray 10 ml 0.1% 101
drops 10 ml 0.05% 71
1Xylene The drug is for local use. Reduces swelling and hyperemia of the nasal mucosa. Lance Farm, Russia spray 10 ml 0.05% 62
0.1% 72
drops 10 ml 0.05% 27
0.1% 32
Xymelin The product has a vasoconstrictor effect on the nasal mucosa, removing swelling. Facilitates the breathing process for 10-12 hours. The active ingredient is xylometazoline. Nycomed Denmark ApS, Denmark spray 10 ml 0.1% 178
0.05% 165
Takeda GmbH, Japan drops 10 ml 0.1% 93
0.05% 93
Otrivin The vasoconstrictor is suitable for patients with sensitive nasal mucosa. The effect occurs a couple of minutes after use and lasts 12 hours. Novartis, Switzerland spray for children 10 ml 0.05% 153
spray, menthol-eucalyptus 10 ml 0.1% 176
spray 10 ml 0.1% 155
0.05% 155
Rinomaris In addition to xylometazoline, this vasoconstrictor contains sea water, which improves the condition of the nasal mucosa and thins the mucus. In addition, beneficial microelements reduce adverse reactions such as irritation and dryness. The effect lasts 12 hours. JSC Jadran Galena Laboratory, Croatia spray 10 ml 0.05% 134
0.1% 112
Rhinorus The drug makes breathing easier and improves patency in the nasal passages. The action begins in a couple of minutes and lasts 10 hours. Synthesis AKOMP, Russia spray 10 ml 0.1% 75
0.05% 72
20 ml 0.1% 91
0.05% 73
drops 10 ml 0.1% 26
0.05% 22
Rhinostop The vasoconstrictor facilitates breathing during rhinitis, acute respiratory infections, sinusitis, otitis, hay fever. ZAO Lecco FF, Russia spray 10 ml 0.05% 34
0.1% 34
Pharmstandard, Russia spray 15 ml 0.05% 89
0.1% 112
Snoop The product removes swelling and hyperemia. The action occurs within a couple of minutes. Stada, Germany spray 15 ml 0.05% 141
0.1% 102
Tizin Xylo The medicine will help clear the nasal passages of accumulated secretions, normalizing breathing. The effect appears after 10 minutes. Johnson and Johnson spray 10 ml 0.05% 117
0.1% 120

Analogues of Rinonorm

Level 4 ATX code matches:
Xymelin Eco

Xymelin

Nazivin

Galazolin

Lazorin

Nazivin Sensitive for children

Otrivin

Naphthyzin

Sanorin

Knoxprey

For the nose

Lazolvan Rino

Afrin

Rhinorus

Eucazoline Aqua

Rinazolin

Grippostad Reno

Farmazolin

Xylometazoline

Nazol Advance

Among the main analogues of Rinonorm are:

  • Galazolin;
  • Nose Spray;
  • Brizolin;
  • Theiss Nazolin;
  • NOS asterisk;
  • Xylene;
  • Xylometazoline;
  • Influrin;
  • Xymelin;
  • Nosolin;
  • Olint;
  • Rinomaris;
  • Otrivin;
  • Rhinorus;
  • Snoop;
  • Rhinostop;
  • Eucazoline Aqua;
  • Sanorin-Xylo;
  • Tizin Xylo;
  • Espazolin;
  • Suprima-NOZ;
  • Farmazolin.

Price Rinonorma

You can buy Rinonorm spray at any pharmacies in Moscow or order it from an online pharmacy store. You can find out the cost of the drug from the table below:

Name Manufacturer Dosage, ml Price, rub.
Rhinonorm, 0.1% Ratiopharm, Germany 15 67
Rhinonorm, 0.05% Ratiopharm, Germany 15 69
Rinonorm-Teva, 0.1% Merkle GmbH, Germany 15 76
Rinonorm-Teva, 0.05% Merkle GmbH, Germany 15 75
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