If you are planning to purchase Nazivin for children (in drops, from 1 to 6 years), you should study the instructions first. Pay attention to indications and contraindications, assess the risk of side effects. A child's body reacts more sharply to chemicals than an adult, so the risk of developing allergies and other negative reactions is higher. When a drug is not suitable, analogues that provide a similar therapeutic effect are considered, even if they differ in composition.
Compound
In 1 ml drops of oxymetazoline hydrochloride 500 µg, 250 µg or 100 µg. A solution of benzalkonium chloride , sodium dihydrogen phosphate dihydrate, EDTA, sodium hydroxide, water, sodium hydrogen phosphate dihydrate - as excipients.
Spray composition: of oxymetazoline hydrochloride . A solution of benzalkonium chloride, sodium dihydrogen phosphate dihydrate, EDTA, sodium hydroxide, water, sodium hydrogen phosphate dihydrate - as excipients.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Vasoconstrictor, alpha2-adrenergic agonist . Reduces swelling of the mucous membrane when applied topically and the amount of discharge. By eliminating swelling of the mucous membranes, it restores breathing and aeration of the paranasal sinuses and middle ear. The use of the drug prevents the development of sinusitis , sinusitis , and otitis media .
In therapeutic concentrations it does not cause hyperemia and does not irritate the mucous membranes. It begins to act in 10 minutes and the effect lasts 12 hours.
Pharmacokinetics
When applied topically, it has no systemic effect. The half-life is about 35 hours. 2.1% is excreted in urine and 1.1% in feces.
Interaction with other drugs
You cannot use different vasoconstrictor drops at the same time. This will lead to an increase in their effect. As a result, the risk of developing negative reactions increases. Nazivin increases blood pressure when used simultaneously with MAO blockers and tricyclic antidepressants.
Read more Instructions for using Vixipin eye drops
Side effects
All side effects are rare:
- sneeze;
- dryness and burning of the nasal mucosa;
- reactive hyperemia after completion of treatment, manifested by nasal congestion (in case of overdose);
- insomnia;
- anxiety;
- headache;
- nausea;
- tachycardia and arterial hypertension (in case of overdose);
- atrophy of the mucous membranes (in case of overdose).
Causes of a runny nose
First, you should consider the main causes of a runny nose and the mechanism of its occurrence. The mucus produced by the inner lining of the nasal cavity has a strong bactericidal effect. It kills most harmful microorganisms that enter the nasal cavity during breathing. When a person's immune defense decreases, swelling occurs in the sinuses, as a result of which the body begins to produce more mucus. An increase in secretion leads to disruption of the normal functioning of the cilia, resulting in the very feeling of nasal congestion. Rhinitis can often be triggered not only by the action of microorganisms, but also by various allergens.
Antihistamines can relieve such sensations, but they have a negative effect on the body. "Nazivin" for children has a milder effect. As a result, doctors often prescribe it to relieve symptoms of an allergic reaction.
Instructions for use of Nazivin (Method and dosage)
Spray Nazivin, instructions for use
Spray 0.05% is prescribed for adults and children over 6 years of age. It is recommended to spray 1 spray into the nasal passages 2-3 times a day. The recommended dose can be used for up to 7 days. If symptoms worsen within 3 days, you should consult a doctor.
Nazivin drops, instructions for use
Adults and children over 6 years of age are prescribed 0.05% drops, 1-2 drops 2-3 times a day. Children from 1 year to 6 years - 0.025% drops, 1-2 drops 2-3 times. Children under 1 year of age are prescribed 0.01% of the drug: newborns 1 drop 2-3 times. The bottle of 0.01% of the drug has a graduated pipette on which the number of drops is marked (1, 2, etc.).
It is possible to administer the drug into the nose in another way: the required number of drops is applied to a cotton swab and the nasal cavity is wiped with it. The duration of use of the drug is 3-4 days.
Contraindications of the drug
Nazivin is not prescribed in a number of cases, including:
- rhinitis, accompanied by atrophic processes in tissues;
- angle-closure glaucoma;
- intolerance to the active component.
Read more Polydex nasal drops - instructions for use
Different forms of the drug have different age restrictions, which should be taken into account.
Use with caution
There are a number of pathological conditions in which it is permissible to use Nazivin, but therapy is carried out under the strict supervision of a doctor, since it is important to monitor the patient’s condition. Relative contraindications:
- increased intraocular pressure;
- during pregnancy and lactation, the drug is prescribed if the probable benefit outweighs the possible harm;
- recent use of monoamine oxidase inhibitors, Nazivin is allowed to be used 10 days after the end of the course of treatment with drugs of this group;
- thyrotoxicosis;
- diabetes;
- severe diseases of the cardiovascular system, such as hypertension, accompanied by frequent crises, as well as angina pectoris.
Side effect
Possible reactions:
- dryness of the mucous membranes of the sinuses;
- frequent sneezing;
- burning in the nose;
- Long-term use contributes to the development of tissue atrophy and drug-induced edema.
After the end of the action of Nazivin, a sharp deterioration in the condition is observed: nasal breathing becomes difficult, swelling intensifies. Sputum is not always released. A runny nose can only be accompanied by a deterioration in the respiratory function of the nose.
Analogs
Level 4 ATX code matches:
Xymelin Eco
Xymelin
Galazolin
Lazorin
Nazivin Sensitive for children
Otrivin
Naphthyzin
Sanorin
Knoxprey
For the nose
Lazolvan Rino
Afrin
Rhinorus
Eucazoline Aqua
Rinazolin
Grippostad Reno
Farmazolin
Xylometazoline
Nazol Advance
Nazol Baby
Drugs that have the same active ingredient: Nazol , Nazol Advance , Sanorinchik , Noxprey , Afrin , Nesopin , Fazin . Analogue drugs that have a similar effect: Galazolin , Xylometazoline , ForNos , Xymelin .
Release form
Children's "Nazivin" is sold in a glass bottle with a special pipette cap. This allows parents to accurately determine the number of drops and prevent the risk of overdose. The bottle itself is made of dark thick glass. The fact is that ultraviolet light can partially destroy the active substance and reduce its concentration in the solution. Naturally, the quality and effectiveness of all therapy will suffer as a result. The bottle is placed in a cardboard package and comes with instructions. Children's "Nazivin" is sold in a volume of 5 ml. The capacity of the bottle for adults is twice as high.
Sometimes the container for storing the solution is made of polymers.
Reviews about Nazivin
Nazivin vasoconstrictor drops, like other drops, should be considered as an “ambulance” and used only for 3-5 days of severe nasal congestion. With long-term use, mucosal atrophy is possible. It should be noted that Nazivin, when used in the recommended dosage regimen, does not cause significant damage to the mucous membrane, is not addictive even with long-term use, and its therapeutic effectiveness, compared to other vasoconstrictor drops, is achieved at low concentrations. Therefore, the 0.01% solution of oxymetazoline of rhinitis even in newborns and infants.
It is a known fact that this drug also has antiviral and anti-inflammatory effects. This explains its high effectiveness in rhinitis of viral etiology. This drug is the only anticongestant that is approved in Russia for use in newborns. Research has shown its high efficiency. This is evidenced by reviews of Nazivin:
- “... I use Nazivin 0.01% children's nasal drops for my 2-year-old child. They act for a long time, so I drop them 2 times a day, but not for long”;
- “... The child often has a runny nose and we can only save ourselves with these drops - 2 days of treatment are enough and the congestion goes away”;
- “...I like these drops most of all. We use it with the whole family, but we give it to children in less concentration”;
- “... It is enough to instill the drops for 1-1.5 days, and then we switch to medicinal drops (such as Pinosol), or simply instill herbal decoctions and treat the runny nose completely.”
Nazivin spray is convenient for use in adults and some people find it more effective than drops. This is true: aerosol forms are distributed more evenly throughout the mucous membrane, which creates a pronounced therapeutic effect. In addition, the spray does not roll into the nasopharynx, as happens when using drops.
special instructions
Do not use drops for longer than recommended by the manufacturer. Nazivin should be used especially carefully to treat children, since patients in this group react more acutely to changes in the treatment regimen and increasing the dose of the drug.
After using increased doses of this drug, disturbances in the functioning of the central nervous system and cardiovascular system may occur. This means that you need to drive with caution, and if the above negative reactions occur, you should refrain from driving for a while.
Nazivin price, where to buy
You can buy the drug at any pharmacy. The price of Nazivin spray 0.05% ranges from 221 rubles. up to 248 rubles, the cost of Nazivin Sensitive spray is 231-352 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Nazivin administered drops.
0.01% 5ml Sofarimex Industria Kimica e Pharmasuetica, S.A. 160 rub. order - Nazivin spray nasal. dosage 22.5 µg/dose vial. 10ml Merck KGaA / Sofarimex Industria Kimika e Pharmasuetica Lda
186 RUR order
- Nazivin Sensitive nasal spray. dosage 22.5mcg/dose 10mlPharmaster/Famar Health Care Services Madrid/Merck KGaA and Co.
RUB 192 order
- Nazivin Sensitive nasal spray. dosage 11.25mcg/dose 10mlPharmaster/Famar Health Care Services Madrid/Merck KGaA and Co.
RUB 176 order
- Nazivin administered drops. 0.025% 10ml Sofarimex Industria Kimica e Pharmasuetica, S.A.
140 rub. order
Pharmacy Dialogue
- Nazivin (sensitive 22.5 µg/dose 10 ml-220 doses spray dosage) Merck KgaA
RUB 216 order
- Nazivin (drops 0.05% 10ml)Merck KgaA
RUB 165 order
- Nazivin (drops 0.01% 5ml)Merck KgaA
RUB 176 order
- Nazivin (sensitive 11.25 µg/dose 10 ml 220 doses nasal spray) Merck KgaA
RUB 207 order
- Nazivin (drops 0.025% 10ml)Merck KgaA
RUB 142 order
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Pharmacy24
- Nazivin Sensitive 0.05% 10 ml spray Merck Selbstmedication GmbH, Nimechchina/Merck KgaA & Co.
Werk Spittal, Austria 65 UAH.order - Nazivin 0.01% 5 ml drops Merck KGaA, Nimechchina
53 UAH order
- Nazivin Sensitive 0.025% 10 ml spray
66 UAH order
- Nazivin 0.025% 10 ml drops Merck KGaA, Nimechchina
55 UAH order
- Nazivin 0.05% 10 ml spray Merck KGaA, Nimechchina
55 UAH order
PaniPharmacy
- Nazivin sensitive liquid Nazivin Sensitive nasal spray 0.025% 10ml Germany, Merck Selbstmedikation GmbH
79 UAH order
- Nazivin liquid Nazivin nasal drops 0.01% 5ml Germany, Merck KGaA
57 UAH order
- Nazivin liquid Nazivin nasal drops 0.025% 10ml Germany, Merck KGaA
58 UAH order
- Nazivin sensitive liquid Nazivin Sensitive nasal spray 0.05% 10ml Germany, Merck Selbstmedikation GmbH
87 UAH order
- Nazivin liquid Nazivin spray 0.05% 10ml Germany, Merck KGaA
64 UAH order
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Doctors' opinions
As mentioned above, Nazivin is considered a fairly effective drug for the treatment of many types of rhinitis. But in some cases, its use can do more harm than good. If you have an individual intolerance to some components of the drug, doctors may prescribe analogues.
Nasal drops containing xylometazoline are often prescribed for treatment. This main active ingredient is found in Rinostop and Xylene. The presented drugs can be used for children aged two years and older. They cannot be used for infants.
Domestic analogues of Nazivin containing oxymetazoline include Nesopin, Nazol and Sialor Rino. It is worth noting that they can only be used by children over 6 years of age. In other cases, use is prohibited.
In some cases, foreign generics can be used. They are similar to Nazivin, but also have a number of limitations. Therefore, in each specific situation, it is recommended that you first carefully read the instructions for the medicine and consult in detail with your doctor.
