The symptoms of approaching menopause are difficult for most women. In addition to the fact that menopause is considered a kind of psychological blow, it is accompanied by many unpleasant manifestations. These include: a feeling of hot flashes to the head, increased blood pressure, emotional instability, etc. To ease this difficult period, there are anti-menopausal drugs. One of these medicines is the drug "Sagenite". Instructions for using this drug are included in the package. Before you start using the medication, you should consult a gynecologist.
pharmachologic effect
The medicine Sagenite is a hormonal drug that has an anti-menopausal effect.
Thanks to it, the mutual functioning of the ovarian→pituitary→hypothalamus system is stabilized.
Ovarian→pituitary→hypothalamus system
Also the drug in tablet form:
- Does not have an estrogenic effect on target organs.
- Activates uterine contractility .
- Stimulates placental perfusion .
- Helps increase the concentration of β-lipoprotein .
- Increases the body's sensitivity to insulin .
Action of the drug in the body
How does Sagenite work? Instructions for use of the drug contain a detailed description of the pharmacological properties of the drug. As is known, changes in hormonal regulation lead to the development of menopausal syndrome. To establish the feedback between the ovaries and the parts of the brain responsible for the normal functioning of the endocrine system, the drug “Sagenite” is used. The drug has a stabilizing effect on the hypothalamic center.
The target organs for this drug are the uterus and smooth muscles of the genitourinary system. Therefore, when entering the body, the drug produces an antispasmodic effect. In addition, it helps improve uterine circulation, thereby relieving pain in the abdomen.
Patients suffering from hypertension and diabetes mellitus should use the drug "Sagenite" with caution. The instructions indicate that the medication enhances the effect of other drugs. These include insulin, diuretics and antihypertensives.
Composition and release form
The drug Sagenite is available in two forms: tablets and capsules. An ointment under this name is not available.
The medicine in tablet form has a concentration of the active component sigetin in the amount of 100 mg.
Medicine in tablet form
The composition is also filled with additional substances :
- Stearic acid.
- Starch.
- Microcrystalline cellulose.
The drug Sagenite in capsules contains 100 mg of sigetin.
Auxiliary components are:
- Stearic acid.
- Potato starch.
- Sucrose.
- Indigo carmine.
- Titanium dioxide.
- Dye.
- Gelatin.
Both Sagenite tablets and capsules are packaged in 10 or 30 pieces.
The drug "Sagenite": instructions
The drug is prescribed by a gynecologist. In this case, the doctor must assess the dynamics of the woman’s condition. Improvement in well-being and disappearance of menopause symptoms should be observed within a week after using the drug "Sagenite". Instructions for use of the medication indicate that the dosage of the drug depends on the severity of premenopausal symptoms. If hormonal changes cause a violent clinical picture, then 100 mg (1 tablet) is prescribed. After a week, the woman should visit the doctor and talk about the effect of the drug. In case of side effects or symptoms of overdose (hypotension, weakness), the dosage is reduced to 50 mg per day. If no therapeutic effect is observed, the medication is discontinued and another drug is selected. The maximum daily dose is 2 tablets.
Women who have been prescribed the drug are often interested in how much Sagenite costs. The price of the medicine ranges from 450 to 600 rubles per package. The course of treatment is 1-2 months, depending on the severity of menopause and tolerability of the drug.
Contraindications
The medicine Sagenite has a small list of contraindications.
These include:
- Pregnancy.
- Metrorrhagia.
- Intolerance to the components of the drug.
- Lactation period.
- Liver dysfunction.
- Kidney failure.
- Hyperlipoproteinemia.
Photo gallery of contraindications:
Pregnancy
Metrorrhagia
Breast-feeding
Liver diseases
Kidney failure
Hyperlipoproteinemia
Side effects
Adverse reactions from the use of the drug Sagenit occur rarely.
No. | Organ system | Adverse reactions from tablets and capsules |
1 | Digestive system | Vomiting/nausea Cholestatic jaundice |
2 | Nervous system | Dizziness |
3 | Genitourinary system | Metrorrogia |
4 | The immune system | Allergic reaction: - Swelling of the eyelids. - Rash. |
In what cases are Sagenite tablets contraindicated?
It should be remembered that the use of the medication is not indicated for everyone. Even despite the presence of signs of menopausal syndrome, in some cases the drug "Sagenite" is prohibited. Contraindications to prescribing the medication include:
- The presence of an allergic reaction after the first use of the medication. Hypersensitivity can be not only to the active substance, but also to auxiliary substances (cellulose, stearic acid, starch).
- Metrorrhagia is bleeding from the genital tract during the period between menstruation.
- Hyperlipidemia detected by the results of a biochemical blood test.
- Chronic liver diseases leading to organ failure.
- Severe chronic renal failure.
For women using antihyperglycemic drugs or insulin, antihypertensive and diuretic drugs, Sagenite should be prescribed with caution. If the condition worsens, the dosage is reduced or the hormonal pills are completely discontinued.
In some cases, a change in condition and a delay in menstruation do not indicate menopause, but the onset of pregnancy. This can be confusing for middle-aged women. Therefore, before you start using the drug "Sagenite", you should exclude the presence of pregnancy. If the lady is in an interesting position, the medicine is discontinued.
Drug interactions
The drug Sagenite enhances the effectiveness of:
- Diuretics.
- Antiarrhythmic drugs.
- Hypotensive.
- Anticoagulants.
Some medications (folic acid and drugs for the thyroid gland) enhance the effects of Sagenite tablets and capsules.
The medicine Sagenite reduces the therapeutic effect of male sex hormones.
Useful video:
Indications for use of the drug
The main indication for the use of the drug is menopausal syndrome. Treatment for this condition is not indicated for all women. The premenopausal period can occur in different ways. Hormonal medications are necessary only in cases of severe menopause. Thus, the following conditions are indications for the use of the drug “Sagenite”:
- Feeling of hot flashes and increased sweating.
- Tendency to depression and aggressive state.
- Memory and sleep disturbances.
- Edema syndrome.
- Degenerative processes of the skin.
Sometimes doctors recommend taking the drug "Sagenite" for preventive purposes. The instructions, however, do not provide for this. Therefore, it is worth approaching this issue individually. In case of severe arterial hypertension and emotional lability, prevention of menopause is allowed. However, the dose of the medication should be less than the therapeutic dose.
Analogues substitutes
Similar drugs to Sagenit are:
- Sigetin is available in the form of tablets, powder and solution. (Russia).
- Abyufen is made in the form of tablets with beta-alanine. (France).
- Sigetin-Standard is produced in tablets. (Russia).
- Klimadinon is available in the form of tablets and drops based on black cohosh. (Germany)
- Soifem is created in the form of tablets based on soybean seed extract. (Poland).
- Cimitsiplant is produced in the form of capsules based on cohosh. (Russia).
Photos of substitutes:
Abyufen
Klimadinon
Soifem
Szigetin
Reviews from doctors
Vanina Alexandra Viktorovna, gynecologist:
“I always give women a choice of several similar drugs, if possible. Most people settle on the drug Sagenite, because it costs less than its analogues. Its effectiveness helps relieve the symptoms of menopause within 14 days.”
Panchenko Alena Dmitrievna, gynecologist:
“I like the drug Sagenite because it almost never causes adverse reactions. This has never happened in my practice.”
Is Sagenit really that good: reviews from those who have taken the drug
Many women note an improvement in their condition after using the drug. Almost everyone points to the effectiveness of the drug "Sagenite". Reviews from those who have taken the drug are, however, not always positive. Some of the women surveyed complained of pain in the liver area. Some note an increase in the activity of ALT and AST enzymes in a biochemical blood test. Women suffering from liver and gallbladder diseases do not recommend the use of this medication. With regard to reducing the frequency and intensity of hot flashes, normalizing blood pressure and improving well-being, patients respond positively to the drug.
Reviews from women
Maria, 51 years old : “As soon as hot flashes and other manifestations of menopause began, I went to the gynecologist. He prescribed me a drug in Sagenite tablets. At first I was in no hurry to buy it, because I saw that the price was not low. But when I bought it, I didn’t regret it. The first two weeks there were no changes. Then the symptoms gradually began to weaken and bother me less often. I feel like I’m 30.”
Anna, 54 years old : “I’ve been taking these pills for several years. Everything is fine in my personal life. There is no discomfort."
Instructions for use Sagenite, dosage
For menopausal syndrome, Sagenit is prescribed orally (1 tablet). regardless of food intake. Daily dose – up to 2 tablets. The course of treatment is 30-40 days.
The advisability of taking this drug should be determined by the specialist observing you - a gynecologist, therapist, endocrinologist.
Features of application
The drug does not affect concentration and therefore does not affect the control of machines and mechanisms; there is no need to give up driving a car or other vehicles.
If there is no therapeutic effect during the first week of taking Sagenit, it should be discontinued.
When taking Sagenite and folic acid simultaneously, the effectiveness of treating thyroid diseases increases. Sagenite enhances the effect of antihypertensive, diuretic and sedative drugs, but reduces the effect of male sex hormones.
During therapy, it is undesirable to consume alcoholic beverages to prevent the development of side effects.