Indications for use
As the instructions for use indicate, Amelotex suppositories are prescribed to eliminate ailments such as arthritis, ankylosing spondylitis, or, in other words, ankylosing spondylitis, as well as for the treatment of inflammation and degenerative conditions. The directly active substance contained in the drug is meloxicam, which helps eliminate pain and osteoarthritis.
Amelotex suppositories are produced in two versions depending on the degree of concentration of the active substance. Each package contains six suppositories.
Special Cautions
- All forms of Amelotext, except gel, disrupt concentration and relax. This must be taken into account by people who drive vehicles or complex machinery.
- During lactation, therapy with this drug is not carried out, since the active substance can pass into breast milk.
- The product should be used very carefully in case of kidney disease and severe liver pathology.
- If Amelotex is prescribed to elderly people, then medical supervision is necessary. It is better to start with a minimum dose and a short course of treatment.
- Some patients experience increased photosensitivity. To reduce the risk of developing photosensitivity, you should avoid visiting a solarium and UV irradiation.
Contraindications for use
Amelotex suppositories should not be used if the following symptoms are present:
- Wounds, scratches and ulcers in the area where the product is intended to be applied. Thus, Amelotex can be used only in those areas of the skin that are free of any damage.
- Inflammatory processes in the gastrointestinal system.
- Intolerance to meloxicam by the body, as well as general sensitivity to non-steroidal anti-inflammatory drugs, including allergic reactions to them.
- Renal and heart failure in patients.
- Nasal and sinus polyposis, bronchial asthma.
It should be noted that alcohol-containing drinks do not interfere with absorption and do not in any way affect the degree of effectiveness of the drug. However, it is necessary to take into account that Amelotex suppositories (the instructions for use confirm this) can have a negative effect on the liver and kidneys, for this reason it would be better not to put additional stress on these organs, and also to completely stop drinking alcohol during therapy.
Reviews
Doctors often prescribe painkillers to patients, as severe pain makes life unbearable. Among them, not the least is Amelotex, which is in great demand.
Numerous reviews from patients taking this remedy confirm the effectiveness of the drug , which quickly relieves painful symptoms.
The advantages include a relatively low price, even many analogs are much more expensive. When compared with similar medications, Amelotex is not toxic, although negative reactions do occur.
We kindly ask site visitors to share your experience of treatment with this drug. By leaving an honest review, you will help people suffering from diseases of the spine and joints to soberly assess the effectiveness of the medication.
Conflicting reviews may raise doubts about the effectiveness of the drug. Indeed, Amelotex is not able to completely cure the disease, but it is famous for its powerful pain relief .
That is why many doctors include this remedy in combination therapy, as it significantly enhances the effect.
Pregnancy and lactation period
The drug should not be used during pregnancy, and, in addition, during breastfeeding. This rule applies to all forms of release of this drug.
For women who have difficulty conceiving a child, it would be better to choose some other drug for treatment, since absolutely all drugs made on the basis of meloxicam have a depressing effect on fertile function. For this reason, in gynecology, when planning a child, this drug is not prescribed to women.
You should also pay attention to the fact that injections with meloxicam can also affect the effectiveness of intrauterine contraceptives, as a result of which they reduce it.
How does Amelotex work in the form of suppositories? Let's figure it out.
The principle of action of the drug "Amelotex" on the body
When it enters the systemic bloodstream in any of the ways (through the skin, the gastrointestinal system, the use of suppositories), Amelotex is able to penetrate the affected cells, and, in addition, to the tissues of the spine and its structure. In this area, a series of chemical reactions are triggered, as a result of which the substance cyclooxygenase-2 is inhibited. This causes a blockade of inflammatory mediators, which are prostaglandins and leukotrienes. This action entails an anti-inflammatory effect.
The antipyretic effect of Amelotex suppositories (15 mg) depends on the blockade of inflammatory mediators, and is also associated with a decrease in the degree of sensitivity of thermoregulation centers in the brain.
The analgesic effect is directly related to the ability of this medication to increase the degree of pain sensitivity, as well as block the pain center in the brain.
Composition of the drug
Gel
Active ingredient: meloxicam (1 mg)
Additional components: water, carbomer, lavender and orange oil, methylpyrrolidone, trometamol, ethanol 95%
Solution
Active ingredient: meloxicam (15 mg)
Additional components: water, glycofurfural, glycerol, meglumine, sodium hydroxide solution, poloxamer, sodium chloride
Pills
Active ingredient: meloxicam (7.5/15 mg)
Additional components: colloidal silicon dioxide, crospovidone, MCC, lactose monohydrate, povidone, magnesium stearate and citrate
Candles
Active ingredient: meloxicam (7.5/15 mg)
Additional components: solid fat, macrogol glyceryl hydroxystearate
Taking Precautions
In cases where patients experience the following symptoms, this drug should be used with extreme caution; the instructions for use for Amelotex suppositories confirm this:
- Hyperkalemia along with coagulation disorders.
- The presence of stomach ulcers, as well as duodenal ulcers, which are in the stage of exacerbation.
- Bleeding in the digestive system.
- Inflammatory processes occurring in the intestines, for example, ulcerative colitis or Crohn's disease.
- Progressive renal pathologies.
- Liver diseases in the active stage, including failure of this organ.
- Chronic failure of the heart muscle.
It is important to pay attention to the fact that if a person smokes, abuses alcohol, has diabetes or is infected with Helicobacter pylori, then he is at risk and should use this drug with caution. Amelotex suppositories are very popular in gynecology.
The effect of Amelotex suppositories on the concentration of attention of patients
When using Amelotex, patients should take into account that therapy may affect the ability to drive normally. When using it, drowsiness is likely to occur, and you may also feel dizzy. Some patients prescribed this drug may even develop severe headaches. Against the backdrop of all this, the required concentration of attention drops noticeably; for this reason, it would be best to refuse to work with all kinds of mechanisms that require maximum concentration.
We will look at reviews and analogues for Amelotex candles below.
Interaction of the drug "Amelotex" with other drugs
When prescribing Amelotex for therapy, it is important to keep in mind that the active substance meloxicam has the following effects:
- The drug should not be used simultaneously with acetylsalicylic acid.
- Along with myelotoxic drugs such as Cyclosporine and Cholestyramine, Amelotex should be used with great caution.
- This provokes an increase in the concentration of lithium contained in the blood plasma.
- The compatibility of Amelotex suppositories, according to reviews, with diuretics represents an additional risk of possible disturbances in the functioning of the kidneys.
- There is a possibility that antihypertensive medications will not be effective enough when interacting with meloxicam.
A doctor should select analogues for Amelotex suppositories.
Amelotex
Active substance:
Meloxicam*
Pharmgroup:
NSAIDs. Oxycams
Average price in pharmacies
Name | Manufacturer | average price |
Amelotex 0.0075 n20 tablet | Pharm, JSC | 138.00 |
Amelotex 0.0075 n6 supp | Pharm, JSC | 136.00 |
Amelotex 0.01/ml 1.5ml n10 amp solution IM | Pharm, JSC | 466.00 |
Amelotex 0.01/ml 1.5ml n3 amp solution IM | Pharm, JSC | 262.00 |
Amelotex 0.01/ml 1.5ml n5 amp solution IM | Pharm, JSC | 345.00 |
Analogs for the active substance:Arthrozan Bi-xicam Lem M-Kam Mataren MELBEC Melbek forte Melox Meloxam Meloxicam Meloxicam DS Meloxicam Pfizer Meloxicam Sandoz Meloxicam STADA Meloxicam-Prana Meloxicam-Teva Meloflam Meloflex Rompharm Mesipol Mixol-Od Mirlox Movalis Movasin Movix Exen-Sanovel | Application area:Ankylosing spondylitis Pain syndrome in muscular and joint diseases Pain syndrome in osteoarthritis Pain syndrome in osteoarthritis Pain syndrome in osteoarthritis Pain syndrome in osteoarthritis Pain syndrome in acute inflammatory diseases of the musculoskeletal system Pain syndrome in acute inflammatory diseases of the musculoskeletal system Pain syndrome in acute inflammatory diseases of the musculoskeletal system Pain syndrome in acute inflammatory diseases of the musculoskeletal system Pain syndrome in rheumatic diseases Pain syndrome in chronic inflammatory diseases of the musculoskeletal system Pain syndrome in chronic inflammatory diseases of the musculoskeletal system Pain syndrome in chronic inflammatory diseases of the musculoskeletal system Pain syndrome in chronic inflammatory diseases of the musculoskeletal system Pain in the joints Joint pain Joint pain during heavy physical activity Painful inflammatory joint lesions Painful conditions of the musculoskeletal system Painful joint conditions Painful traumatic joint lesions Diseases of the spinal column Ankylosing spondylitis Ankylosing spondylitis-Marie-Strumpell disease Pain in the musculoskeletal system Shoulder pain Joint pain Joint pain Joint pain due to injury Musculoskeletal pain Osteoarthritis pain Osteoarthritis pain Pain due to joint pathology Rheumatoid arthritis pain Rheumatoid arthritis pain Pain in chronic degenerative bone diseases Pain in chronic degenerative joint diseases Inflammation in osteoarthritis Inflammation in rheumatoid arthritis Inflammatory arthropathy Inflammatory and degenerative joint diseases Inflammatory disease of the musculoskeletal system Inflammatory joint disease Inflammatory diseases of the musculoskeletal system Gonococcal arthritis Degenerative forms of rheumatoid arthritis Destructive arthritis Pediatric rheumatoid arthritis Deforming arthrosis Deforming osteoarthritis Deforming osteoarthritis of joints Musculoskeletal disease Diseases of the musculoskeletal system Diseases of the musculoskeletal system and connective tissue Changes in the hand with osteoarthritis Musculoskeletal infections Osteoarticular pain Marie-Strumpel's disease Monoarthritis Non-infectious arthritis Non-rheumatic arthritis Exacerbation of rheumatoid arthritis Exacerbation of rheumatoid arthritis Osteoarthritis Osteoarthritis Osteoarthritis in the acute stage Osteoarthritis of large joints Acute inflammation of musculoskeletal tissue Acute inflammatory disease of the musculoskeletal system Acute inflammatory condition of the musculoskeletal system Acute arthritis Acute pain syndrome in osteoarthritis Acute osteoarthritis Acute gouty arthritis Acute rheumatism Acute rheumatoid arthritis Acute articular rheumatism Post-traumatic osteoarthritis Post-traumatic osteoarthritis Reactive arthritis Rheumatic pain Rheumatoid arthritis Rheumatic pains Rheumatic arthritis Rheumatoid arthritis Rheumatic osteoarthritis Rheumatic arthritis Rheumatic spondylitis Rheumatoid arthritis Rheumatoid arthritis Active rheumatoid arthritis Rheumatoid periarthritis Rheumatoid polyarthritis |
Side effects from Amelotex
Side effects are expressed in the manifestation of symptoms in patients such as hyperemia, peeling of the skin, allergic reactions in the form of burning, itching and urticaria. In addition, erythema multiforme, papular-vesicular rashes and photosensitivity are observed.
On the part of the skin, there is a possibility of the formation of epidermal necrolysis. In relation to the respiratory system, the occurrence of bronchial spasms cannot be ruled out.
The body’s nervous system is able to respond to the administration of the drug with the following symptoms:
- The occurrence of tinnitus, headaches.
- Decreased concentration along with confusion.
- Disorientation in space and drowsiness. This is confirmed by the instructions for Amelotex candles.
There is also the possibility of disturbances in the functioning of the hematopoietic organs, which can be expressed in anemia, leukopenia and thrombocytopenia. Regarding the functioning of the cardiovascular system, there are risks of developing the following unpleasant symptoms:
- Peripheral edema.
- Increased blood pressure is common.
- Cardiopalmus.
- A feeling of a rush of blood, which is most often felt in the chest area, as well as on the face. This is confirmed by the instructions for use and reviews of Amelotex.
Many side effects can be mentioned regarding the functioning of the digestive system:
- The stomach may ache and, at the same time, gastritis may develop or worsen.
- Hepatitis and hyperbilirubinemia are possible.
- Bleeding in the digestive organs, including those that occur in a latent form, cannot be ruled out.
- Abnormal bowel habits occur, with possible constipation and diarrhea, as well as colitis, belching and flatulence.
- Perforation of the gastrointestinal tract occurs.
- The activity of liver transaminases increases.
- Nausea, stomatitis, vomiting, esophagitis and erosive and ulcerative lesions of the digestive organs are likely.
Quite often, some problems arise in the functioning of the urinary system, which are expressed in the form of hematuria, hypercreatininemia and albuminuria. On this basis, the development of interstitial nephritis and acute renal failure also occurs, which may be accompanied by swelling and an increase in the concentration of urea in the blood serum.
Among other things, vision problems are likely, for example, a decrease in visual acuity and the occurrence of conjunctivitis. Patients often develop allergic reactions to the substances of the drug, which result in angioedema.
This is indicated in the instructions for use for Amelotex candles. Analogues of the drug are also used in gynecology.
Analogs
Medicinal drugs such as Movalis and Meloxicam have properties and degrees of impact similar to Amelotex.
The drug "Movalis" was developed in Germany, and its price reaches eight hundred rubles per package. This product is produced in the form of tablets, as well as injections, suspensions and rectal suppositories, like Amelotex. Dosing, as well as the method of using this medication, directly depends on the severity of the patient’s disease.
The advantages of this medicine include the fact that it can be prescribed to adolescents starting from the age of twelve. In addition, the drug acts as an original medicine.
Its unconditional disadvantage is the price, as well as the fact that it cannot be used during pregnancy, during the lactation period, and, moreover, against the background of systematic alcohol consumption.
As for Meloxicam, its price is significantly lower compared to its previous analogue and amounts to no more than three hundred rubles per package. This product is produced in Israel. It is produced in the form of suspensions, tablets, as well as rectal suppositories and injections. It has antipyretic, anti-inflammatory and analgesic effects.
The advantage is, as already noted, low cost. Due to the fact that this medical product has a protective shell, it does not have a noticeable negative effect on the organs of the digestive system.
The downside is a large list of various contraindications along with side effects. Meloxicam negatively affects the health of the liver and kidneys. In addition, there is a high possibility of purchasing a fake.
Price
You can purchase this product at any pharmacy in Russia or order it in an online store. The price of the drug depends on the form of the drug.
Release form | On Russian territory | On the territory of Ukraine |
5 ampoules of solution | 390 rubles | from 380 to 520 hryvnia |
20 tablets (7.5 mg) | 64 rubles | 150 hryvnia |
10 tablets (15 mg) | 130 rubles | — |
6 candles | 140 rubles | 500 hryvnia |
Gel (50 g) | 350 rubles | 350 hryvnia |