"SEPTOLETE total" (spray): instructions for use, price, analogues

"SEPTOLETE total" (spray): composition

The instructions for use of Septolete total spray provide a detailed composition of the drug, which includes:

Active components:

• benzydamine hydrochloride is a synthetic analgesic and antiseptic that has an anti-inflammatory effect;
• Cetylpyridinium chloride is a medicinal antiseptic with an antifungal and antimicrobial effect.

1. Additional components:

• 96% ethanol solution - tartaric acid, which acts as an antioxidant;
• peppermint oil – metabolite with local analgesic, antiseptic and irritant effect
• glycerin is a dehydrator and dermaprotector, with a mild laxative effect"
• saccharin – food additive as a sugar substitute;
• emulsifier macrogolglycerol hydroxystearate ( macrogol glyceryl hydroxystearate);
• purified water as a base.

Available in the form of a transparent yellowish solution. Sold in 30 ml plastic bottles with a dispenser and cannula.

How does it affect the body? (Pharmacodynamics)

The active component benzydamine belongs to the group of non-steroidal anti-inflammatory drugs and acts as an antiseptic, analgesic and local anesthetic. The second main substance – cetylpyridinium chloride – has antimicrobial, antifungal and virucidal pharmacological effects

Only benzydamine is absorbed into the body, penetrating into the blood plasma through the mucous membrane. As a result, there is no systemic interaction between both active ingredients. At the same time, the amount of benzamidine is not enough for systemic manifestations. The level of absorption of benzydamine in a spray that has a local effect is lower than when taken in those dosage forms that promote its complete dissolution in the oral cavity.

Elimination of active components from the body is carried out through the kidneys with urine, mainly in the form of inactive metabolites.

Indications for use:

The medicine is used to treat symptoms:

• acute and chronic pharyngitis;
• acute forms of tonsillitis (angina);
• acute and chronic laryngitis
• stomatitis;
• alveolitis;
• periodontal diseases (gingivitis, periodontal disease, etc.).
• sore throat and other symptoms of ENT diseases.

Contraindications

Aerosol is not recommended for use in the following cases:

• high individual intolerance to the components of the spray;
• under 6 years of age.

Important! Since the instructions for use of the Septolete total spray do not contain information about laboratory studies on the effect of the drug on the development of the fetus and the likelihood of its active components getting into breast milk, use during pregnancy and lactation is allowed under the supervision of a therapist and if there are vital indications for the mother.

It is recommended to stop breastfeeding while using the aerosol.

Patients with bronchial asthma should also take it with caution.

Side effects

During treatment, adverse reactions of the body may occur in the form of allergic rashes and itching, nausea and diarrhea. In case of ulcerative lesions of the mucous membrane, you should seek help from a physician.

Pharmacological properties

The therapeutic effect of the drug is determined by its composition. So benzydamine belongs to the group of NSAIDs. This means that the substance has a local anesthetic, anti-inflammatory and analgesic effect.

The pharmacological effect of benzydamine is achieved by blocking the production of prostaglandins, which provoke the inflammatory process. Therefore, the substance is used to relieve swelling, pain and hyperemia in the oropharynx.

The price of the medicine is 400 rubles.

Cetylpyridinium chloride is an ammonium compound that has a powerful antiseptic and antimicrobial effect. The substance also has disinfectant and antifungal properties.

The principle of action of cetylpyridinium is based on interaction with lipoproteins of the cell membranes of pathogens, as a result of which the membranes are destroyed and the microbes die. The substance destroys gram-positive bacteria, viruses and yeast-like fungi.

Most of the active components of Septolete are excreted in urine in the form of inactive metabolites. T ½ and C-max for the drug are the same as for most drugs.

"SEPTOLETE total" (spray): instructions for use

The drug is used topically. The permissible dosage depends on the age of the patient:

1. children from 6 to 14 years old - 1 injection 3-4 times a day, no more than 4 times a day;
2. adolescents from 14 years of age and adults - 1-2 injections every 2 hours, but not more than 5 times a day.

The duration of treatment is no more than a week. If there is no improvement, consult a therapist.

Considering the local effect of the drug, it does not have a direct effect on the patient’s psychosomatics, which allows it to be taken while working with precision mechanisms and automation, or while driving vehicles.

Overdose

In rare cases, when the permissible daily dose is increased, an overdose is possible, which can manifest itself in the form of:

• profuse sweating,
• ataxia,
• vomiting,
• hives,
• skin itching,
• increased dryness and irritation of the mucous membranes,
• bronchospasms,
• xerostomia,
• laryngospasms,
• emotional excitability,
• photophobia,
• hypotension,
• convulsive conditions, etc.

In this case, you must seek urgent medical help.

There is no exact data on the interaction of the aerosol with other drugs. However, it is not recommended:

• use it simultaneously with other local antiseptics;
• combine with drugs that contain anionic compounds (for example, in toothpaste).

How to take it correctly?

1. Do not brush your teeth an hour before or after the procedure.
2. Before use, remove the protective cap and check the serviceability of the dispenser-sprayer by pressing the pump 1-2 times.
3. Insert the cannula into the mouth, pointing it at the sore spot and give 1 (children) or 2 (adults) injections.
4. After use, wipe the nebulizer and cannula with an antibacterial wipe and close the cap.
5. Do not eat or drink for at least 30 minutes after using the aerosol.

Important! It is not recommended to combine the drug with milk (drink before or after taking it), since milk reduces the therapeutic effect of cetylpyridinium chloride.

Contraindications

Septolete-Plus cannot be used for:

• Individual hypersensitivity to contained substances
• History of intolerance to local anesthetics
• Alcohol addiction
• Methemoglobinemia (increased hemoglobin levels with a high concentration of oxidized iron in red blood cells)
• Children and teenagers up to 18 years of age (for spray), up to 6 years of age (for lozenges)
• Genetic fructose intolerance.

The use of Septolete should be carried out under medical supervision when:

• Brain diseases
• Head injuries
• Bronchial asthma
• Old age
• Lesions in the oral cavity
• Disorders of the respiratory system.

"SEPTOLETE": analogues

Considering the multicomponent composition of the drug, there are no completely direct structural analogues of Septoleta. However, pharmacies offer many medications based on benzydamine. These include:

Agidak Grotex is a domestic pharmaceutical product with a local spectrum of action. is prescribed in complex and monotherapy for inflammation and infections of various etiologies of the oral mucosa. Price – from 240 rubles;

Benzydamine Akrikhin is a medicine from a Moldovan pharmaceutical manufacturer. Acts as an analgesic and anti-inflammatory in the treatment of dental and ENT diseases. Price – from 190 rubles;

Tantum Verde is an Italian spray that has an anti-inflammatory and analgesic effect. Used topically to treat pain syndromes, oral infections and ENT diseases. Price – from 300 rubles;

Oralcept is a Macedonian medicine produced in the form of a spray. It has an anti-inflammatory, analgesic and antifungal effect. It is used in the treatment of acute and chronic forms of pharyngitis, tonsillitis, laryngitis, periodontal diseases and oral mucosa. Price – from 260 rubles;

Asterisk ENT is a famous Vietnamese medication, now produced in aerosol form. It effectively helps in the treatment of infectious-inflammatory diseases of the oral cavity and periodontium. Price – from 150 rubles;

Vertum ENT is a Russian structural analogue with a pronounced anti-inflammatory and antiseptic effect. Effective in the treatment of inflammation of the oral and periodontal mucosa of various etiologies. Price – from 200 rubles.

In terms of the second active component, analogs of Septolete are:

Gramidin is a throat spray from a pharmaceutical manufacturer with a dual active composition, including gramicidin C dihydrochloride and cetylpyridinium chloride. It is an anti-inflammatory antiseptic. Used to treat pharyngitis, tonsillitis, laryngitis, stomatitis and periodontal diseases. Price – from 330 rubles.

Release forms

Average cost – 287 rubles.

Septolete Plus Spray is produced in the form of a transparent liquid of a colorless or yellowish tint. Packaged in 30 ml, which is equivalent to 160 doses. The antiseptic is placed in a dense polyethylene bottle with a built-in dispenser (pump) and sprayer. In a cardboard pack there is a bottle and an accompanying insert-description.

Septolete-Plus lozenges are biconvex lozenges with a bright blue coating. The product is packaged in blisters of 9 pieces. A cardboard pack contains 2 plates and an accompanying annotation.

Med-Lime lozenges are biconvex lozenges in a dark yellow coating. The drug is also placed in blisters of 9 pieces. The pack contains 2 packs, instructions.

"SEPTOLETE": reviews

Mom often complained of pain and burning in her throat (you know what it’s like). All kinds of remedies that the local local doctor prescribed did not help. At first we tried traditional methods - the result was zero. One day she went to a pharmacy, where a pharmacist friend recommended Septoleta Total in the form of a spray. The instructions were followed strictly, and after a couple of days my mother felt relief, after which all the symptoms went away. For almost the entire winter she has not complained of unpleasant symptoms, she feels well, and probably the remedy suited her perfectly.

After such an unpleasant procedure as FGDS, I felt discomfort in my mouth. For the first day I thought it was the consequences of the procedure. Then, looking in the mirror, I opened my mouth and examined the mucous membrane, I realized that it was nothing more than stomatitis ulcers all over the mucous membrane, it was painful not only to eat, but also to speak, and considering that I also had to work with stomatitis, I began treatment. I bought this spray at the pharmacy; it combines an antibiotic + pain relief; such an integrated approach literally saved me. Applying to stomatitis ulcers is a little painful (burning and pain in the first few seconds) then replaced by a feeling of freshness and painlessness. I was actively treated with it for the first 3 days, and it worked.

Precautionary measures

When using an antiseptic you should consider:

• The bottle of Septolete-Plus spray is intended for individual use only. During treatment, it should not be given to other people.
• The spray is not intended for inhalation and should not come into contact with the eyes.
• It is not recommended to take tablets before meals or during meals.
• If there are wounds in the oral cavity, then you should refrain from using the product in any form, since the active substance interferes with healing.
• If after three days of treatment with Septolete-Plus the disease intensifies and the temperature does not drop, then the antiseptic should be discontinued and consult a doctor to adjust the treatment regimen.

Overdose

To date, there has been no information about cases of overdose. Due to the fact that Septolet-Plus contains a minimal amount of active substance, intoxication is practically impossible. It is assumed that after taking a large amount of the drug, disturbances in the gastrointestinal tract, diarrhea, nausea, vomiting, and stomach pain are possible. Symptoms of overdose develop especially quickly in children. To eliminate an overdose, it is necessary to stop taking the antiseptic, empty the stomach, and carry out symptomatic therapy.