Pharmacodynamics and pharmacokinetics
The Pharmacopoeia indicates that the formula of Sodium Sulfacyl is CsHgSaNaOsS-b^O. INN – Sulfacetamide . The recipe in Latin will contain the name Sulfacylum-natrium.
Eye drops inhibit the absorption of PABA and also prevent the synthesis of PABA-containing growth factors of microorganisms.
The medicine is characterized by antibacterial properties. It acts on streptococci , gonococci , E. coli , chlamydia , pneumococci , actinomycetes .
An aqueous solution of Sodium Sulfacyl has a slightly alkaline reaction, which allows it to be instilled into the conjunctival sac of the eye.
Properties
As the instructions indicate, “Sodium Sulfacyl” has a pronounced antimicrobial effect, influencing the life processes of harmful microorganisms and preventing their active reproduction. "Sulfacyl" is active against the following bacteria:
- streptococci;
- coli;
- gonococci;
- pneumococci;
- actinomycetes;
- toxoplasma;
- chlamydia.
After instillation, Sulfacyl penetrates into all fluids and tissues of the eye. The substance can enter the systemic bloodstream only through the inflamed conjunctiva in such small quantities that it has no effect on the human body.
So, “Sodium Sulfacyl” is “Albucid”? Yes, it's the same thing.
Indications for use
Eye drops are used for gonorrheal eye diseases, conjunctivitis , blenorrhea , purulent corneal ulcers, blepharitis and other eye diseases. The drug can be used by both children and adults, including for the prevention of blenorrhea in infants. In the case of purulent processes, it stops them and accelerates the healing of the cornea.
Prescribed for the treatment of streptoderma and staphyloderma , infections caused by Escherichia coli .
The medicine can be used orally in the case of colibacillary urinary tract infections, mastoiditis , puerperal sepsis and other infectious diseases .
Instillation into the nose and ears
Quite often, pediatricians prescribe Sulfacil instillation into the nose. The solution is widely used in the treatment of bacterial and purulent nasal discharge, as well as against the background of acute respiratory viral infections or mild acute respiratory infections. For more than one generation of parents, Sulfacil has been used to treat runny noses in children, and they are satisfied with the results obtained.
“Sulfacyl” dries out the nasal mucosa, reduces the amount of mucus secreted and makes the child’s breathing easier. It is important to remember that the drug can be used only in cases of uncomplicated diseases, when there is no risk of damage to the ENT organs and sinuses. Also, the solution should not be used if strong antibiotics are prescribed.
Another area of application for Sulfacyl is the treatment of external otitis in a child. However, its use is considered safe only if the eardrum is intact. At the moment, it is generally accepted that Sulfacil is not an effective otolaryngological drug. The main purpose of the solution is to eliminate diseases of the eyes, and not the nose and ears. However, the drug can be used in cases where classical otolaryngological medications are not available.
That is, in case of emergency, when nothing else is at hand, you can use Sulfacil, but its clinical effectiveness in the case of otitis media has not been proven. The drug is instilled in one or two drops into each ear up to four times a day for a weekly course. If there is no positive dynamics after several days of using the solution, you should stop using it and consult a doctor. The specialist will select another, more effective drug or prescribe antibiotics that will quickly and effectively relieve inflammation.
Instructions for use of Sulfacyl Sodium (Method and dosage)
For those who are indicated for Sulfacyl Sodium eye drops, the instructions for use indicate that instillations should be carried out into the conjunctival sac . For adult patients, a dosage of 1-2 drops is prescribed. The product is applied 5-6 times a day (every 4-8 hours). In childhood, a solution of 10 percent and 20 percent is indicated. To prevent the development of blenorrhea, immediately after birth, infants are instilled with 2 drops of the product, and then 2 drops every 2 hours.
The medicine can also be used in ointments based on petroleum jelly 10-30% in the case of blepharitis and eczema of the eyelid skin.
Instructions for use of Sulfacyl Sodium indicate that the duration of therapy directly depends on the severity of the disease. It is not recommended to use the medicine for longer without consulting a specialist.
In the case of gonorrheal eye diseases, combination therapy . Instill a 30% solution or dust the affected area with powder; in addition, take the drug by mouth.
Infected wounds are treated using the powder.
The maximum single dosage for adults orally is 2 g, the maximum daily dosage is 7 g.
Before using the drops for the first time, the cap is screwed all the way down. A spike on the inside pierces a hole in the membrane. Before use, you need to hold the bottle in your palm for a while to warm the product to body temperature. The cap is unscrewed and after light pressure on the body of the bottle, the solution is dripped into the eyes. Then the bottle should be closed again.
Additional Information
The main indication for treatment with Sulfacyl sodium drops is conjunctivitis of a viral or bacterial nature. It is necessary to instill drops in each eye, even if there is no inflammation in one. During the procedure, the dispenser should not touch the affected area: otherwise, there is a risk of infection of the healthy cornea, and the course of therapy will be delayed.
Interaction with other drugs
Drops have a depressing effect on some medications, so before treatment you should discuss the dosage and possible replacement with your doctor. It is prohibited to instill simultaneously with any alkaloids and silver-based products: the components enter into a chemical reaction, provoking severe allergies.
The antibacterial effect is significantly reduced when used simultaneously with the following medications:
- Novocaine;
- Dicaine;
- Anestezin;
- direct acting anticoagulants.
When used with Diphenin or salicylic acid, the drug may exhibit toxicity and side effects. Drops should be used with extreme caution in patients who constantly use Furosemide or thiazide diuretics: eye hypersensitivity is often observed when sodium balance is disturbed.
Vacation conditions and shelf life
To purchase the drug, you do not need a doctor's prescription: the prescribed composition can be found in any pharmacy. When sealed, the bottle with dispenser can be stored for up to 2 years from the production date at room temperature 20–25°C. Sulfacyl drops should be left in a place protected from direct sunlight to avoid heating or oxidation of the composition.
The shelf life of the medicine after opening is no more than 4 weeks. This short-term storage is due to the peculiarities of the chemical formula: with prolonged contact with oxygen after opening the bottle, sulfacyl oxidizes and loses its medicinal properties. Therefore, for the treatment of mild forms of conjunctivitis, it is better to purchase a small package of 5 ml.
The price of the drug depends on the manufacturer and the volume of the bottle. Children's drops with a concentration of 10% cost from 19 rubles. The cost of Sulfacyl sodium 20% starts from 23 rubles.
Special instructions and precautions
The drug does not affect the patient’s ability to drive vehicles and machinery. Mild impairment of visual acuity disappears within 10–15 minutes, so it can be used for work that requires precision and coordination.
Sulfacyl sodium 10% is often used to prevent eye infections in newborns: when passing through the birth canal, infection with pathogenic microflora occurs, increasing the risk of blenorrhea. It is used once after delivery, treating each eye. In rare cases, with bacterial rhinitis, you can drop drops into the baby’s nose, replacing more allergenic antibiotics with a simple and safe remedy.
Read more Trilactan eye drops: instructions for use and reviews
Sulfacyl sodium has repeatedly participated in clinical trials. It is not absorbed into the bloodstream, so many experts approve of its use in the treatment of women at any stage of pregnancy, during breastfeeding. The only recommendation is strict adherence to dosage and precautions when treating inflamed eyes.
Interaction
If you need to take other drugs in combination with Sulfacyl Sodium, you should consult your doctor.
The bacteriostatic effect of the drug is reduced when combined with Novocaine , Anestezin and Dicaine . And its toxicity increases when interacting with Diphenin , salicylates and para-aminosalicylic acid . When used together with indirect anticoagulants, their specific activity may increase.
Drops should not be used together with salts of some alkaloids, with agents containing silver salts, with zinc sulfate, as well as with acids and substances that have an acidic reaction.
Storage conditions
The drug should be stored at a temperature not exceeding 15 degrees. What is the shelf life of Sodium Sulfacyl after opening? As a rule, after opening the bottle, the drops should be stored in the refrigerator. However, unopened packaging can also be placed on the refrigerator door. If the bottle is kept sealed, the drug can be stored for no more than two years. Once opened, the drops can be used for four weeks. The formation of a precipitate in the solution indicates the expiration of the shelf life or deterioration of the contents of the bottle.
Is it possible to instill sodium sulfacyl in a child?
Analogs
Level 4 ATC code matches:
Albucid
The following analogues of the drug are known: Albucid , Acetopt , Ophthalemide , Sebizon , Sulfaprocul , Sulfacyl , Sulfacyl soluble , Almocetamide , Octzetan , Prontamide , Sobizon , Sulfacetamide Sodium , Sulfacyl Sodium-DIA .
Albucid and Sulfacyl Sodium
Which is more effective, Albucid or Sulfacyl Sodium, is often asked on forums. Experts answer that these are actually synonyms. Thus, Albucid is Sodium Sulfacyl. This drug is also available in the form of eye drops and is used for diseases caused by streptococci , pneumococci , and gonococci . At the same time, relatively recently, Albucid and Sulfacyl Sodium began to be used for instillation into the nose.
Contraindications
The only contraindication that the manufacturer points out in the instructions is intolerance to chemical components. It manifests itself with the following symptoms:
- burning;
- redness of the sclera;
- increased itching;
- the appearance of swelling of the lower or upper eyelid.
To exclude the problem, you should conduct an allergy test on the skin of your hand before the first procedure. There is no clear restriction on the age at which Albucid and Sulfacyl sodium are used, and whether it can be used for newborns. Given the simplicity of the composition and the low percentage of adverse reactions, it is recommended for young children in the treatment and prevention of viral conjunctivitis.
Side effects
In rare cases, eye drops provoke temporary complications, accompanied by itching and burning. This is due to the appearance of erosions or an allergic reaction. In the absence of swelling and other unpleasant symptoms, treatment with Sulfacil can be continued.
Some patients experience a white coating during therapy after using sulfacylamide-based drops. This is not a side effect, but residues of the active substance on the skin of the eyelid. It can be washed off with saline solution, clean water or Furacilin diluted in water.
Overdose
Before using the solution, you must carefully read the instructions. If the dosage is violated, a temporary deterioration in the condition, a sensation of a foreign body or “sand” in the eyes, redness, itching or swelling of the eyelid may occur. In such a situation, it is better to stop using the drops before visiting an ophthalmologist.
Read more Instructions for using Okulohel drops for children
Price of Sodium Sulfacyl, where to buy
The price of Sulfacyl Sodium eye drops 20% is about 50 rubles. In some pharmacies the cost of this product reaches 85 rubles. The average price of Sulfacyl Sodium in Ukraine is 10 hryvnia.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
ZdravCity
- Sulfacyl sodium eye drops 20% tube-drops.
2ml 2 pcs. PFK Renewal JSC Renewal PFK 80 RUR order - Sulfacyl sodium eye drops 20% 1.5 ml 2 pcs. Federal State Unitary Enterprise Moscow Endocrine Plant
69 RUR order
- Sulfacyl sodium-DIA eye drops 20% vial - cap. 10ml JSC Diapharm
27 RUR order
- Sulfacyl sodium-SOLOpharm eye drops 20% tube-dropper 0.5 ml 5 pcs Grotex LLC
118 RUR order
- Sulfacyl sodium-SOLOpharm eye drops 20% vial. 5ml "Grotex" LLC
136 RUR order
Pharmacy Dialogue
- Sulfacyl sodium 20% dropper tube 1.5 ml No. 2Moscow endocrine plant
48 RUR order
- Sulfacyl sodium bufus dropper tube 20% 2ml No. 2Update PFK JSC
69 RUR order
- Sodium sulfacyl 20% dropper tube 1.5 ml No. 2Update PFC JSC
21 rub. order
- Sulfacyl sodium-Solopharm (tube drops 20% 5ml)Grotex LLC
71 RUR order
show more
Pharmacy24
- Sulfacyl sodium 30% 10ml eye drops TOV"FZ"Biopharma", Ukraine
16 UAH.order - Sulfacyl Sodium 20% 10 ml No. 1 eye drops PAT "Farmak", Ukraine
14 UAH order
Reviews
Andrey, 22 years old: “I work at a construction site, and on one of my usual days a wooden sliver got into my eyes. The first symptom was pain, then it went away, but in the morning irritation arose, followed by inflammation. There was a cutting pain, a burning sensation, and increased lacrimation. The doctor prescribed Sulfacyl, which I used 5 times a day. I only needed 5 days for my illness to subside.”
Maria, 35 years old: “For 3 years I suffered from conjunctivitis 2 times. After the first infection, I was prescribed the drug Sulfacyl sodium. I carried out installations 5 times a day for 7 days. After just 3 days, the long-awaited relief came, and at the end of the therapeutic course, the disease completely left me. And when the inflammation recurred, I no longer thought about what to do, but immediately bought sodium sulfacyl.
