Diclofinac suppositories for female diseases: when is it prescribed and how to use it?

Evgeniy Nikolaevich Konoplev

Reading time: 6 minutes

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Pharmacies offer a large number of anti-inflammatory drugs used to treat gynecological diseases, prostatitis, radiculitis and more. Among them are Diclofenac suppositories. This remedy is good because it does not contain hormones, has an analgesic effect, relieves swelling and successfully fights infections that cause diseases.

Main characteristics of Diclofenac suppositories

Diclofenac suppositories are a drug that has analgesic properties, as well as mild anti-inflammatory and antipyretic properties.

Compound

The suppositories contain the only active ingredient - diclofenac sodium, the content of which in one suppository can be 50 or 100 mg. It has a pronounced analgesic effect and also reduces/stops inflammation. Additional components include:

• Witepsol H15 is a solid fat, which is the basis for making candles;
• colloidal silicon dioxide – “works” as an enterosorbent;
• Miglione 812 is a solvent that promotes complete and rapid absorption of the main active ingredient.

We recommend reading the article about when Diclofenac suppositories are prescribed for prostatitis. From it you will learn about the principle of action of the drug Diclofenac for prostatitis, when the effect will be, instructions for using suppositories, possible side effects, what can be replaced. And here is more information about when to use Voltaren diclofenac suppositories.

Prescription for the drug

A prescription is not required to purchase the drug - Diclofenac suppositories are freely available. But at the same time, experts insist on their use only as prescribed by the attending physician.

How they work

The candles act in a complex way:

• relieve, make tissue inflammation less pronounced;
• do not have an intense antispasmodic effect;
• provide blood thinning and accelerate blood flow;
• lower body temperature;
• relieve pain (very quickly, the desired effect is achieved literally 1-3 minutes after administration of the suppository);
• reduce the severity of swelling of inflamed tissues.

The main effect of Diclofenac in suppositories is to suppress the synthesis of substances that provoke the progression of the inflammatory process.

How long does it take to work?

Depending on where the source of pain is located, the suppositories begin to act within 30-60 minutes. If they are used to relieve pain in the rectum (for example, with the progression of hemorrhoids), then a decrease in the severity of pain occurs almost immediately after the administration of the suppository.

The resulting effect lasts on average for up to 8 hours, sometimes the patient notes relief for 12 hours.

Which is better - injections or suppositories?

It is impossible to answer unequivocally what is better to use - injections or Diclofenac suppositories, because everything depends on the developing pathology and the location of the problem area. For example, if there is pain in the lower back or muscles of the cervical spine, then it is advisable to perform injections. And for gynecological diseases, during the treatment of diseases of the rectum, suppositories will be appropriate.

Release form, manufacturers

There are many medications based on the active substance diclofenac, many have the same commercial name. It is impossible to say which option is better, since each has a different composition, concentration of the active substance and different release forms. The most common types of drugs with diclofenac, except suppositories:

• cream;
• pills;
• injection;
• eye drops;
• ointment;
• gel.

The price for Diclofenac suppositories varies depending on the manufacturer, as does the drug in other forms. The product is produced in the form of rectal suppositories by different companies: Ratiopharm, MFF, Altfarm and others. They all have the same indications and active ingredients. The lowest cost is for those drugs that are produced in Russia, India or Belarus. The price will be higher for English, Dutch, German or Polish drugs.

As for analogues, their commercial name will be different, since they may differ in composition and form, and have slightly different indications for use. The most famous analogue is Voltaren. Also known are Diklak, Klafen, Naklofen, Diklovit, etc.

Before replacing one product with another, medical advice is required.

Diclofenac suppositories: instructions for use

Instructions for using Diclofenac suppositories involve performing the procedure strictly according to the algorithm:

1. Cleanse the intestines - visit the toilet or do an enema, take a laxative.
2. Wash your hands with soap, ideally treat them with any disinfectant solution.
3. Lie on your back, raise your legs and insert the suppository into the rectum - it should go completely there.
4. It is not advisable to get up and change body position for 1-2 hours.

The drug is prescribed in a minimum daily dose; it can be exceeded only with the permission of the doctor - for example, if the pain syndrome is too severe, the disease is severe. Adult patients and children over 16 years of age are prescribed 100-150 mg of the drug per day - 2-3 suppositories every 8 hours. This dosage does not require adjustment if the patient is elderly (65 years or older).

If the patient is severely weakened and has a deficiency of body weight, then he is allowed to administer only 1 50 mg suppository per day.

The duration of use of Diclofenac in suppositories is set strictly on an individual basis, but doctors strive to shorten the course, since the drug may cause too strong side effects.

Watch this video for instructions on how to use Diclofenac suppository:

Indications

The drug can be used as symptomatic therapy or as part of the main treatment, as an additional one, but in any case, suppositories are administered only according to indications:

• inflammatory processes in muscles, joints and ligaments;
• progressive/acute bursitis;
• pathologies of a neuralgic nature;
• cystitis of acute form or chronic in the acute stage;
• myalgia;
• gout at the initial stage of its course;
• prostatitis (inflammation of the prostate gland);
• hernias located in the intervertebral space;
• thrombophlebitis;
• gynecological diseases accompanied by severe pain;
• inflammatory processes in skeletal muscles;
• arthritis, regardless of the nature of their origin;
• painful menstruation.

Diclofenac suppositories can solve the problem of pain due to toothache and headache, unexplained pain in the spine, some ENT diseases of infectious origin, and in the postoperative period.

How to apply depending on temperature

At high body temperatures, Diclofenac suppositories are not prescribed as an exclusively antipyretic agent, but it is advisable to use them if pain syndrome is present against the background of hyperthermia. Suppositories are administered 1 piece 1-2 times a day, the dosage of the active substance is 50 mg per manipulation.

After administering Diclofenac, you need to wait 1-2 hours and monitor your body temperature. If they do not decrease, another antipyretic agent should be used.

How to use for back pain and other problems with the musculoskeletal system

For back pain, suppositories are used 2-3 times a day, suppositories 50 mg for each procedure. This drug is believed to be especially effective for many musculoskeletal problems:

• gout – Diclofenac inhibits the accumulation of uric acid in the joints;
• sciatica – stops the development of the inflammatory process;
• chronic juvenile arthritis – relieves inflammation in the joints, makes pain less pronounced;
• lumbago – relieves lower back pain during physical activity;
• Ankylosing spondylitis - the drug successfully fights inflammation, quickly and permanently relieves obsessive pain syndrome;
• arthrosis - does not affect changes in joint cartilage, but “works” well as a painkiller;
• radiculitis – eliminates inflammation in the nerve roots of the spine;
• rheumatism – stops the inflammatory process in connective tissue;
• neuralgia of the spine - suppositories quickly relieve a severe attack of pain.

For prostatitis, hemorrhoids

Regardless of the reason for the development of prostatitis, Diclofenac suppositories will definitely be introduced into the therapeutic course. The effect after administration appears within 40-60 minutes, the main active ingredient of the drug stops the inflammatory process in the tissues of the organ, and this leads to a decrease in swelling - urination is restored, the patient is practically not bothered by pain.

For hemorrhoids, suppositories are used to reduce inflammation and pain directly in the pathological focus. Since after the introduction of the suppository the main active ingredient almost immediately enters the problem area, the therapeutic effect occurs much faster (compared to the use of tablets).

The antipyretic properties of Diclofenac in suppositories are weak in these diseases, but the drug can relieve hyperthermia directly in the affected organs.

For migraine

It is advisable to use Diclofenac suppositories for migraines only if the attacks are accompanied by nausea and vomiting. This pharmacological form of the drug is recommended by doctors for those who have a history of diseases of the stomach/duodenum, liver, and are simply contraindicated from taking the drug in tablets.

Severe migraine involves the administration of 3 suppositories per day at equal intervals, each suppository 50 mg. If the headache is too severe, the attacks last continuously for several hours, then you can use suppositories with 100 mg of the active substance.

Pathogenesis of migraine

Can it be used for children

For children under 6 years of age, the drug is not used at all; for older children (up to 16 years), it is recommended to reduce the daily dosage to 50 mg - 1 suppository is administered. The time of administration is determined individually. For example, if the patient is bothered by pain in the morning, then the procedure is performed immediately before going to bed the night before.

Is it possible during pregnancy, lactation?

In the first and second trimester of pregnancy, Diclofenac suppositories are not prescribed, an exception is made only if the mother’s condition is very serious and the pain poses a real danger to her life. In the third trimester, the drug is strictly contraindicated for use - it reduces the contractility of the uterus, which provokes premature closure of the ductus arteriosus in the fetus.

During lactation, the main active ingredient of suppositories freely penetrates into breast milk, so a nursing woman should avoid using Diclofenac for the entire period.

Is the drug allowed in old age?

In old age, the drug is permitted if there are no general contraindications to its use. The dosage remains unchanged, but if the progressive disease is very severe and the pain is constant, then the standard daily dosage may be exceeded by up to 200 mg of the main active ingredient. In this case, suppositories are administered 4 times a day at equal intervals.

Are suppositories prescribed for problems with the kidneys and liver?

Suppositories are prescribed for renal and hepatic colic (they resemble contractions in a woman during childbirth and are easily diagnosed by patients). The drug is suitable as an “ambulance” until doctors arrive.

With a full course of therapy for kidney/liver pathologies, suppositories can also be included in the prescription list. If they do not have the desired effect, then the doctor must change treatment tactics and adjust his own prescriptions.

How many days can you use and continue the course of treatment?

The course of treatment with suppositories is determined individually, but according to general recommendations, Diclofenac can be used for 3 days in a row. Sometimes, to improve and stabilize the patient’s condition, doctors extend the course of taking suppositories to 5-7 days.

Contraindications to rectal suppositories

Contraindications to rectal suppositories based on diclofenac sodium are:

• established hypersensitivity to the main or additional components of the drug;
• a history of bronchial asthma, rhinitis and conjunctivitis of allergic origin;
• diagnosed proctitis;
• third trimester of pregnancy;
• peptic ulcer of the stomach/duodenum;
• erosive damage to the mucous membrane of the gastrointestinal tract.

Bronchial asthma
Diclofenac suppositories are prescribed with caution for:

• high blood pressure;
• Crohn's disease;
• renal failure;
• infectious diseases of the respiratory system;
• suspected bleeding in the gastrointestinal tract;
• pathologies of the heart and blood vessels;
• previous myocardial infarction;
• critically low body weight;
• hepatic porphyria.

These conditions are not categorical contraindications, but it is better for such patients to use suppositories in therapy under the supervision of doctors.

Side effects of diclofenac sodium

Diclofenac sodium can have side effects on the functioning of almost all body systems:

• digestive - nausea and vomiting (may be with blood), diarrhea and flatulence, gastritis and ulcerative lesions of the mucous membrane, damage to esophageal tissue and jaundice (increased bilirubin in the blood), hepatitis and glossitis, stomatitis and pancreatitis, cirrhosis of the liver;
• central nervous – headaches of varying severity, convulsions of the upper/lower extremities, depression, psycho-emotional tension, apathy and drowsiness, memory problems, sleep disturbances, aseptic meningitis;
• dermis - hair loss, urticaria, development of Lyell's and Steven-Johnson syndromes;
• sense organs – tinnitus, blurred visual acuity, “veil” before the eyes, flickering black “fly spots”;
• urinary – nephrotic syndrome, renal failure, frequent urination, papillary necrosis;
• cardiovascular – pain in the area of ​​the anatomical location of the heart (in the sternum), myocardial infarction, complication of existing thrombotic diseases;
• respiratory – severe shortness of breath at rest and during physical exertion, asthma, pneumonia.

An allergic reaction, which manifests itself as anaphylactic shock and Quincke's edema, can also be a side effect.

Can there be an overdose?

Cases of overdose are not recorded if the suppositories are used strictly according to the instructions and in accordance with the prescriptions of the attending physician. Theoretically, if the daily dosage of the drug is exceeded, the following may occur:

• changes in the blood count - anemia, leukopenia;
• insomnia, nightmares during sleep;
• depression, emotional instability;
• headache;
• stroke;
• noise in ears;
• blurred vision;
• pronounced decrease in blood pressure;
• urinary retention in the body;
• yellowing of the sclera and skin;
• hallucinations;
• heart attack;
• severe tachycardia;
• skin rash, itching.

Low blood pressure
If at least one of the symptoms of an overdose is present, then you should immediately call an ambulance. Before the doctors arrive, you should do the following:

• cleanse the intestines with an enema (plain warm water);
• give a sorbent such as Polysorb, Enterosgel or activated carbon to drink;
• Provide the victim with plenty of fluids.

Indications for use

The drug can be used for symptomatic treatment or as part of complex therapy. The instructions list the indications for Diclofenac suppositories:

• inflammation of ligaments, joints or muscles;
• neuralgic pathologies;
• bursitis;
• myalgia;
• gout;
• intervertebral hernia;
• inflammation of skeletal muscles;
• arthritis of various origins;
• cystitis;
• prostatitis;
• thrombophlebitis, etc.

Suppositories for rectal administration can be prescribed by doctors for inflammatory processes and pain after operations, for acute pain in the spine, for headaches or toothaches, infectious ENT diseases and more.

Renal or hepatic colic can be relieved with their help when used together with antispasmodic drugs.

Suppositories are also recommended for prostate pathologies of various types, except for prostate cancer. For prostatitis, the product is good because all its components enter the diseased organ as quickly as possible thanks to the method of administration - rectally, and do not cause harm to the mucous membranes and other organs. But Diclofenac suppositories for prostatitis will only effectively help with an integrated approach to therapy, which includes not only taking this and other drugs, but also performing special exercises and undergoing procedures.

Diclofenac suppositories in gynecology: what they help with, how to use

In gynecology, Diclofenac suppositories help with pain of any etiology; they are used for:

• pain syndrome during menstruation;
• inflammatory processes in the ovaries (adnexitis);
• pathologies of the fallopian tubes;
• adhesive process;
• infectious diseases of the genital tract;
• salpingophritis;
• polycystic ovary syndrome;
• cysts in the fallopian tubes and ovaries.

Where to insert - into the rectum or vaginally

Suppositories need to be inserted into the rectum, but sometimes doctors prescribe them vaginally - for example, if the source of pain is located directly in the vagina. Often this use is practiced for inflammatory processes in the vagina - colpitis, as well as for thrush (candidiasis), which is severe and accompanied by severe pain.

It should be borne in mind that vaginal administration of Diclofenac suppositories often provokes the development of a powerful allergic reaction - a woman will complain of itching, heavy discharge, and swelling of the vulva. The main active substance can act on the mucous membrane of the organ as an irritant, and this leads to the formation of erosive lesions.

Watch this video on how to properly insert a rectal suppository:

After childbirth

After childbirth, Diclofenac is highly undesirable to use if the patient is breastfeeding a newborn. Such prescriptions are advisable only for severe pain in a woman that cannot be relieved by other drugs. Doctors recommend using 1 50 mg suppository per day and inserting it into the rectum.

The duration of use of suppositories is 3 days, during this time and plus another 2 days you need to stop breastfeeding the baby.

For inflammation of the ovaries

For inflammation of the ovaries, Diclofenac in the form of suppositories is used twice a day with a gap of 8-10 hours between manipulations. The daily dosage should not exceed 100 mg, but in case of particularly severe pathology, the concentration of the main active ingredient may be increased to 200 mg per day.

The duration of use of the drug depends on the patient’s condition and the dynamics of the disease, but doctors do not prescribe it for longer than 5 days.

During menstruation

For painful periods, suppositories help alleviate the patient’s condition for the entire period of regular bleeding. Suppositories can be used every day throughout the entire period of menstruation, but gynecologists recommend limiting it to 3 days.

Suppositories are administered 1 piece 2 times a day; it is better to choose a drug with a lower concentration of diclofenac sodium - 50 mg in one suppository.

From thrush

For thrush, the drug is used for 5-10 days (full course of therapy), but only if the patient has no contraindications or conditions requiring caution. Suppositories are administered once a day; it is advisable to perform the procedure at night - this way the maximum effect is achieved.

If suppositories are prescribed vaginally, this is done only in the first 1-2 days of treatment of the disease to relieve an acute condition. Further therapy is the introduction of suppositories rectally.

Cost and special instructions

Before use, a number of special instructions should be taken into account, in particular when it comes to use during pregnancy. Treatment is possible, but under strict control and only in the first two trimesters; it is better not to use the product during breastfeeding. If therapy continues for a long time, you need to be checked in the laboratory for indicators of blood clotting and liver and kidney function.

As for interactions with other drugs, compatibility gives the following effects:

• diuretics - their effect is reduced, the risk of developing hyperkalemia increases;
• acetylsalicylic acid - the concentration of the active substance of suppositories in plasma decreases, the risk of bleeding increases (as with other anticoagulants);
• sleeping pills, hypoglycemic and antihypertensive drugs - their effect is reduced;
• glucocorticoids and other non-steroidal anti-inflammatory drugs - increased risk of side effects;
• Cyclosporine or Paracetamol - increases the likelihood of nephrotoxic effects;
• Sertraline, Citalopram, Fluoxetine and other selective inhibitors - increases the risk of bleeding in the gastrointestinal tract;
• Colchicine and Corticotropin - increased risk of gastric bleeding;
• Verapamil, Diltiazem, Nifedipine and other drugs for blocking tubular secretion - the concentration of the active substance in the plasma increases, which increases the toxicity of the drug;
• Antibacterial drugs based on quinolone - a high risk of seizures.

After taking it, it is not recommended to drive or perform other work that requires quick reactions, as there is a risk of developing side effects from the central nervous system. Combining the drug with alcohol is prohibited, since the gastrointestinal tract must be healthy and clean before administering suppositories.

The cost of the product depends on the manufacturer, the amount of active substance, general composition and other factors. The cheapest options are Russian-made; English ones will cost much more.

For example, for Diclofenac 100 mg suppositories the price will be from 40 to 100 rubles, and if they have a dosage of 50 mg, then from 15 to 70 rubles, respectively. English-made candles cost 150 rubles and more at the pharmacy.

Doctors recommend that before starting therapy, at least temporarily, stop drinking alcoholic beverages and quit smoking. In addition, the doctor should be informed about concomitant diseases and methods of their treatment. In some cases, together with other drugs, suppositories can cause side effects that are difficult to get rid of.

Despite the relatively large number of possible side effects, the drug is effective and popular. It quickly affects the affected area and can simultaneously cope with several symptoms of a particular disease.

Why do you want to go to the toilet after using Diclofenac?

After using the Diclofenac suppository, the patient always wants to go to the toilet - this is a natural reaction of the body, which is why the instructions indicate the need for preliminary bowel movements. Additional components in the suppository act on the rectal mucosa as an irritant and provoke an act of defecation. It is difficult for the patient to restrain the urge, so it is recommended not to change the lying position for 2 hours after inserting the suppository.

If bowel movement does occur, then it is necessary to use Diclofenac again - the active substance is released in the feces, and there will be no therapeutic effect.

Overdose and side effects

Unlike other drugs based on the same active substance, but in other dosage forms, suppositories do not have a negative effect on the liver, kidneys and digestive organs. But they can still cause a number of side effects , including:

• unpleasant taste in the mouth;
• flatulence;
• abdominal pain;
• diarrhea and constipation;
• burning in the area of ​​insertion;
• nausea.

In case of individual intolerance to the components of the drug, side effects increase, as when used together with other anti-inflammatory non-steroidal drugs.

An overdose can manifest itself in the form of the listed symptoms, and also be accompanied by headache, vomiting, and tinnitus. Sometimes blood pressure may rise and seizures may occur.

Causes of pain from Diclofenac suppositories

Pain from Diclofenac suppositories can also appear in a new place - directly in the rectum; such a reaction is provoked by internal hemorrhoids (inflamed, with bleeding) and fissures in the anus or intestinal mucosa. The use of Diclofenac on open wounds is contraindicated, even if it is supplemented with other components.

If such a syndrome occurs, you must immediately cleanse the rectum of the drug (give an enema) and change treatment tactics.

Contraindications

Before treatment, you need to study the list of contraindications, in the presence of which suppositories cannot be administered to patients. It is strictly forbidden to use them in such cases as:

• haemorrhoids;
• colitis;
• heart, liver or kidney failure;
• colitis;
• cervical erosion;
• bronchial asthma;
• ulcer at the acute stage;
• performing coronary artery bypass grafting;
• hyperkalemia;
• proctitis;
• bleeding;
• children under 16 years of age.

Under strict control, use is possible in the presence of a number of diseases and symptoms. For example, the drug is prescribed with extreme caution to patients with diabetes mellitus, those with coronary heart disease, stomach ulcers, vascular diseases, Crohn's disease, general weakness of the body, low body weight and the elderly.

The dosage is selected individually, taking into account all the characteristics of the body.

Drug interactions

It is prohibited to use Diclofenac suppositories in combination with other medications without the consent of your doctor. Such “complex” therapy can give an unexpected effect:

• with digoxin and lithium - these substances are detected in the blood after 5 days of administration;
• with diuretics and blood pressure lowering drugs – they stop providing the proper therapeutic effect;
• with cyclosporine - a toxic “blow” occurs to the kidneys;
• with non-steroidal or glucocorticosteroid drugs - the adverse reaction to them increases significantly;
• with anticoagulants – the risk of internal bleeding becomes maximum;
• with Methotrexate - it becomes a toxin for the body, poisoning occurs.

You cannot use suppositories and take hypoglycemic drugs at the same time - the latter have too pronounced an effect, the patient may fall into a coma. If, in parallel with suppositories, the patient takes antibacterial drugs from the quinolone category, then convulsions of the lower or upper extremities are possible.

Pharmacological group

The drug Diclofenac belongs to the group of non-steroidal anti-inflammatory drugs and is a derivative of phenylacetic acid. The product has a pronounced analgesic and anti-inflammatory effect. Has moderate antipyretic activity. The mechanism of action of the drug is closely related to the inhibition of the activity of the main enzyme due to the metabolism of arachidonic acid, which acts as a precursor of prostaglandins, which have an important role in the development of inflammatory processes, pain and increased body temperature.

The analgesic effect is due to peripheral and central mechanisms. The active substance in concentrations equivalent to those recommended for a specific category of patients does not suppress the synthesis of proteoglycans in cartilage tissue. For rheumatic diseases, the medicinal composition reduces the intensity of pain in the joints, at rest and during movement, and also eliminates morning stiffness and swelling in the joints.

The product provides an increase in the range of movements and their amplitude. The drug relieves post-traumatic and post-operative pain. The product can be used to eliminate various inflammatory edemas. The drug actively relieves pain during the period after injuries and after surgical interventions, the drug relieves swelling of postoperative wounds.

It is worth considering that the drug inhibits platelet aggregation and, with prolonged use, has a stabilizing effect. About 50% of the active substance is metabolized when passing through the liver. When used rectally, metabolism occurs slowly, the time to reach maximum plasma concentration is about 3 hours. The concentration of the active substance depends on the dose used by a patient of a certain age. Maximum concentrations vary significantly in a linear relationship with the dosages used.

The active substance does not accumulate. Binding to blood proteins, namely albumin, reaches 100%. The active substance penetrates into the synovial fluid, the maximum concentration is observed in the third hour after use. It is metabolized in significant quantities to form some metabolites that are pharmacologically inactive. The half-life from blood plasma is 2 hours, from synovial fluid 6 hours. About 60% of the received dose is excreted through the formation of metabolites through the kidneys. Less than 1% is excreted unchanged. The remaining mass of metabolites is eliminated from the patient’s body with bile.

Analogues of the drug

Analogues of the drug include:

• Voltaren - rectal suppositories, available in dosages of the main active ingredient of 50 and 100 mg, have an identical analgesic effect, cost - 315-367 rubles;
• Diclovit - rectal suppositories of 50 mg, produced in Russia, 10 pieces of suppositories cost 145 rubles;
• Diclofenac - rectal suppositories 100 mg, have a more pronounced effect, cost 10 pieces - 94 rubles.

We recommend reading about the form in which Diclofenac is prescribed for radiculitis. From the article you will learn about how Diclofenac will help with radiculitis, a treatment regimen for radiculitis with Diclofenac injections and tablets, and alternative treatment options. And here is more information about how to correctly perform electrophoresis with Diclofenac.

Diclofenac suppositories are an effective pain reliever, which is intended for rectal administration and is used to alleviate the condition of patients with gynecological diseases, pathologies of the musculoskeletal system and pain of any origin. It has many side effects, so it should be used only as prescribed by a doctor, although it is available without a prescription.

Description and composition

Diclofenac is a suppository presented in the shape of a cylinder with a pointed end. Rectal suppositories are white or almost white in color; the presence of minor yellow inclusions is acceptable. The active ingredient of the medicinal composition is Diclofenac sodium. Auxiliary components included in the product:

• colloidal silicon dioxide;
• Magliol;
• hard fat.

Applications and dosages

The dosage regimen is determined individually. It is recommended to use the drug with a minimally effective and short course of therapy. The drug is used rectally.

for adults

The maximum daily dose for patients in this age category is 150 mg per day. If the patient is indicated for long-term treatment, it is optimal to use the drug 50 mg 3 times a day. The exact dosage regimen is determined together with the attending physician.

for children

Diclofenac sodium can be used by children over 6 years of age. In this case, the maximum effective dose of the drug is determined based on the patient’s body weight. The maximum daily dose for children should not exceed 150 mg.

for pregnant women and during lactation

It is not recommended to use the drug during pregnancy and breastfeeding due to the high risk of adverse reactions. The use of the drug during lactation requires the patient to stop breastfeeding.

Side effects

During the use of the drug, various adverse reactions may occur. As a rule, such violations are observed quite rarely. Patients may experience manifestations of disorders of the digestive tract and nervous system. Dermatological reactions cannot be excluded. With prolonged use, the genitourinary system may develop acute renal failure. From the hematopoietic system, acute thrombocytopenia may develop. Patients suffering from individual sensitivity to the active substance may develop allergic reactions.