The most effective treatment for diseases of the upper and lower respiratory tract are inhalations. Inhalation therapy is prescribed to children of all ages, and if you once had to use a pan with a steaming broth in it to carry out the procedure, today inhalations are carried out using a nebulizer (inhaler device). There are many drugs that can be used in a nebulizer, for example Laferobion, which has recently appeared on the pharmaceutical market.
The drug Laferobion has established itself as a safe, non-toxic product, approved for use by children from the first month of life.
Interaction with other drugs
Without any problems, you can combine antibacterial agents with the drug “Laferobion”. Suppositories, reviews of which can be found on many forums, also combine well with antimicrobial drugs, as well as glucocorticosteroids. Practice shows that the drug “Laferobion” copes well with diseases in the initial stage. Therefore, it is advisable to give this drug to children at the first symptoms of ARVI, and then the baby will get rid of the disease in 1-2 days, while avoiding unwanted complications. In addition, the effectiveness of these suppositories increases significantly when used with other medications that have an immunomodulatory effect. The course of therapy with this drug is determined by the doctor individually, depending on the form of the disease, as well as the age of the child.
pharmachologic effect
The active ingredient Laferobion has antiviral, antitumor and immunomodulatory effects, while it is recombinant human interferon and has no toxic effects.
Laferobion reaches its maximum concentration when administered subcutaneously or intramuscularly after 4-10 hours.
Laferobion increases immunomodulatory activity, suppresses the proliferation and growth of viruses in infected cells. According to reviews, Laferobion is effective and safe in the treatment of infants from various infectious diseases.
Dosage for infants
Use the medication rectally.
"Laferobion 150000" - candles for children, namely, for newborns and premature babies. After all, this dosage is designed specifically for them. The drug is completely safe, so it is prescribed even from the first days of a baby’s life. A dosage of 150 thousand IU is suitable for children from birth to 1 year. One suppository of the drug is administered 2 times a day with an interval of 12 hours. If the baby has a bacterial infection, then the doctor can increase the amount of medication taken up to 3 times a day, with an exposure time of 8 hours. The duration of therapy is from 5 to 7 days. The product can be used in courses, with breaks between them of 5 days.
The recommended number of courses for ARVI is 1; pneumonia – 1 or 2; meningitis – from 1 to 2; sepsis – from 2 to 3.
Indications for use of Laferobion
According to the instructions, Laferobion is used as part of complex therapy for infections caused by:
- Hepatitis B virus, in severe and moderate forms;
- Mixed infections, viral or bacterial, including in infants under 1 month;
- Herpes virus, including herpetic eye lesions, herpetic skin rashes, genital herpes, herpes zoster;
- Human papillomavirus.
Laferobion is also used as part of complex therapy for multiple sclerosis and cancer:
- Tumors of various locations, including bladder, ovarian, kidney, and breast cancer;
- Melanomas of the skin and eyes;
- Kaposi's sarcomas;
- Multiple myeloma;
- Other malignant tumors of various localizations.
Dosage for children from 1 year
The drug is administered rectally.
For influenza and ARVI, Laferobion suppositories are placed for 5 days:
- Children from 1 to 7 years old - 500 thousand IU twice a day, 1 suppository.
— Children from 7 to 14 years old – 1 million IU 2 times a day, 1 suppository.
- Boys and girls over 14 years old - 1.5 million IU each. They will also have to administer Laferobion (suppositories) rectally twice a day.
The instructions for children and their parents also indicate that it is necessary to observe the interval between the use of suppositories. The interval must be at least 12 hours. The course of treatment is usually 10 days. If necessary, the doctor may prescribe repeated therapy 5 days after the end of the first.
Pharmacological authorities
Pharmacodynamics.
LAFEROBION – antiviral, antimicrobial, anti-inflammatory, immunomodulatory, antiproliferative agent. The biological action of interferon is characterized by the following effects: antiviral – suppresses the replication of viruses (adenoviruses, influenza viruses, etc.) due to the inhibitory effect on the transcription process and broadcasts; antiproliferative – suppresses the proliferation of cells (mostly DNA and RNA-borne viruses); Immunomodulation – enhancing the phagocytic activity of macrophages and the specific cytotoxicity of target lymphocytes. Interferon initiates the synthesis of a specific enzyme – protein kinase, which interrupts the translation of phosphorylation of one of the initiating factors of this process; activates a specific ribonuclease, which degrades the messenger RNA of the virus. The effects of interferon also include: stimulation of the production of other cytokines, induction of specific enzymes.
Pharmacokinetics.
I didn’t screw around.
Contraindications
“Laferobion” are candles (the instructions for children and adults describe in detail how to use them correctly), which are allowed for almost everyone and, by the way, are not addictive. Only in rare cases, young patients may experience increased sensitivity to the components of the drug, which manifests itself in the form of allergic reactions. This medicine is also not recommended for those who have problems with the thyroid gland, as well as for severely impaired liver and kidney function. However, such problems are rarely observed in children at their young age, so we can assume that the drug is suitable for everyone.
Contraindicated
Increased sensitivity to interferon alpha-2b and other components that are included in the medical supply, severe forms of allergic illness in the anamnesis; thyroid dysfunction; the presence of severe visceral damage in patients with Kaposi's sarcoma; serious heart-judgmental illness; psoriasis; manifestations of impaired liver function and/or liver function; epilepsy and other diseases of the central nervous system (including functional ones); chronic hepatitis due to aphids with progressive or decompensated liver cirrhosis; chronic hepatitis in patients who are recovering from or have recently stopped taking immunosuppressant therapy (in addition to a short course of corticosteroid therapy); history of autoimmune hepatitis or other autoimmune diseases. Suppression of the myeloid germ of hematopoiesis. Vaginism and breastfeeding period.
Side effects
In some situations, girls and boys may experience undesirable manifestations after rectal use of the drug Laferobion 500000. Candles, the instructions for use of which are clear and accessible, may have the following side effects, which, by the way, occur extremely rarely:
- Hives.
- Chills and lethargy.
- Increased body temperature.
But if the listed symptoms in children take their parents by surprise, then it is worth warning them in advance so that they do not worry: these signs are observed sporadically, and if they exist, they disappear immediately after stopping the medication.
Price
"Laferobion" - candles whose price is not fixed. They can be purchased at any pharmacy. After all, this drug is quite popular and effective. Its cost is influenced by several parameters: dosage, the number of suppositories included in the package, as well as the markup of the pharmacy where the medicine Laferobion is sold. Candles, the price of which, by the way, is quite reasonable, given the excellent effect, on average can be purchased at the following cost:
— Suppositories 150 thousand IU in the amount of 5 pieces - about 200 rubles.
- Candles 500 thousand IU in the same quantity - approximately 280 rubles.
— Suppositories 1 million IU per 10 pcs. – 660 rubles, and for 5 pcs. – 370 rubles.
Compound
active ingredient:
interferon alfa-2b;
1 bottle contains 100,000 IU of recombinant human interferon alpha-2b;
Excipients:
sodium chloride, dextran-70, potassium dihydrogen phosphate, disodium phosphate dodecahydrate.
Dosage form.
Nasal powder.
Basic physical and chemical properties:
lyophilized powder or white porous mass. Hygroscopic. The dissolved drug is a clear, slightly colored liquid.
Pharmacotherapeutic group.
Interferons. ATX code L03A B05.
Positive opinions of people
Laferobion candles for children have mostly positive reviews. So, many mothers write that this drug saves their offspring from another viral attack. And if a parent lights a candle for his son or daughter on time, then the very next day the child feels much better. And a day later, not a trace of the disease was visible. The remedy simply does not allow the infection to penetrate deeper, it blocks it. Therefore, the effectiveness of the drug “Laferobion” is obvious and practically proven.
Also, many parents who have discovered this remedy like that it comes in the form of candles. For them, this is a fairly convenient way to administer the medication. After all, children for the most part do not like to drink any syrups or swallow tablets. And then I put in a candle - and that’s it! The child may not even feel it, because the suppository can be inserted without problems even when the child is sleeping. And the very next day you can admire the excellent condition of your son or daughter. Another plus is that the suppositories themselves are small in size, unlike suppositories of other medications.
This drug also impresses with its price. True, recently the cost of Laferobion suppositories has increased, but not only this medicine has become more expensive. But, despite this, the product remains quite popular, because the price relative to the effect is still quite adequate. Therefore, if you want your child not to get sick for 2 weeks, and, God forbid, he does not develop complications, then purchase Laferobion suppositories just in case. Put them in the refrigerator and use them when the first signs of ARVI appear in your offspring.
When to use
The drug can be used in children both for the treatment and prevention of viral diseases of acute respiratory infections, acute respiratory viral infections, and influenza. Laferobion is also indicated for mixed viral-bacterial and herpes infections, hepatitis B, C, D, leukemia, meningitis and many other ailments.
For children
The drug is prescribed to newborns and premature babies for the treatment of respiratory diseases, pneumonia, intrauterine infection with herpes, candidiasis, chlamydia and other infections.
Spectrum of action
Diabetes mellitus, gastritis, asthma, gastrointestinal inflammation, pyelonephritis, cancer - this is not the entire list of problems for which Laferobion is prescribed.
For colds
Most often, the drug is used as a nasal remedy for the prevention and treatment of colds accompanied by a runny nose, inflammatory processes in the nasopharynx and lower respiratory tract. However, inhalations with Laferobion carried out through a nebulizer are most effective. You should start nebulizer treatment at the first signs of a cold, since after 3 days from the onset of the disease the drug will not have the desired effect.
Negative reviews from people
Unfortunately, the drug “Laferobion” also has negative reactions. But, fortunately, their number is so small that it is easily covered by positive reviews. The fact is that negative opinions are left by those parents who used this tool incorrectly. Thus, many mothers and fathers lit these candles when their children were already developing an active form of the disease: their daughter or son had been lying with a fever for two days, a runny nose and cough did not allow them to sleep. It is not surprising that the drug “Laferobion” did not help them in this case. After all, it is in such a situation that the remedy is useless. And you need to know about this. The drug is effective only at the initial stage of the onset of the disease. Laferobion suppositories are essentially a protective and prophylactic agent. And if the child already has a stuffy nose, has a fever and a whole bunch of cold symptoms, then there is no point in taking this drug. After all, viruses in this case already feel great in the body, and interferon (a substance of protein origin that is secreted by healthy cells) will no longer penetrate into infected cells.
And if the cells are still healthy and they are filled with this substance, then they will not allow viruses to reproduce further, and the remaining infected ones will be in such small quantities that the body will simply eliminate them. Therefore, the child will have a very mild form of the disease or the cold will not be noticeable at all.
Now you know a lot of interesting and important information about the drug "Laferobion". Suppositories, instructions for use of which must be included in the package with the medicine, are a real salvation for many parents in the early stages of colds in their sons and daughters. After all, the drug is able to suppress viruses in the first days of the onset of ARVI, and the very next day the child will feel better, if not excellent. Therefore, parents should take note and, if possible, purchase Laferobion suppositories for their children, purchasing those suppositories that correspond to the age of their boy or girl.
