Vaginorm-S (Vagi C) vaginal suppositories/tab 250 mg 6 pcs

pharmachologic effect

Vaginorm C is a suppository for intravaginal use to improve vaginal microflora and prevent recurrent infections. The medication contains ascorbic acid, which has the following therapeutic effects:

• antiseptic and anti-inflammatory effect;
• a favorable environment for the growth and reproduction of lactobacilli, which improve the acidity of the vagina and make up a healthy microflora;
• preventing the development of anaerobic infections, since the acidic environment created by the main substance and lactobacilli is harmful to them;
• destruction of pathogenic microorganisms leading to vaginosis and vaginitis.

Release form

They produce Vaginorm suppositories for intravaginal use.

There are analogues of Vaginorm based on the active substance - Celascon effect Vitamin C, Cevicap, ascorbic acid. But you can discuss the possibility and method of using ascorbic acid according to Vaginorm’s indications only with your doctor.

Another widely used analogue of Vaginorm is the drug Acilact, which is indicated for diseases of the genitourinary system, but its active ingredient is lactobacilli acidophilus, so the question of replacing Vaginorm should also be discussed with your doctor.

Indications for use of Vaginorm S

The drug and analogues are used in the following cases:

• disruption of healthy vaginal microflora;
• reduction of adverse reactions after the use of antibiotics and certain groups of medications;
• frequent relapses of vaginosis and vaginitis;
• vitamin deficiency and vitamin C deficiency in the body;
• preparation for planned surgical interventions, improvement of the condition of the vagina before childbirth in pregnant women;
• reducing the risk of gynecological diseases due to the activity of anaerobic microorganisms.

Vaginorm S - instructions for use

There are 6 suppositories in a package of medicine. They are used 1 every evening, before bed, intravaginally, i.e. in a lying position, insert as deep as possible into the vagina. The course lasts 6 days; in special conditions it can be extended by a doctor to 2–3 weeks.

To protect your underwear from traces of dissolved candles, it is advisable to use panty liners. For best results, the suppository should be kept in cool water for a few seconds before insertion.

Before prescribing the medication Vaginorm S, the doctor must make sure that there are no restrictions on the use of suppositories - vulvovaginal candidiasis (also known as thrush) and intolerance to the components.

Vaginorm-S (Vagi C) vaginal suppositories/tab 250 mg 6 pcs

Dosage form

Vaginal tablets 6 pieces per package.

Composition in 1 vaginal tablet

Active substance: ascorbic acid 250 mg.

Excipients: polymethylsiloxane 10 mg, lactose monohydrate 670 mg, hypromellose 60 mg, magnesium stearate 10 mg.

Pharmacotherapeutic group

Antiseptic.

pharmachologic effect

Ascorbic acid lowers vaginal pH by inhibiting bacterial growth and helps restore and maintain normal vaginal pH and flora (Lactobacillus acidophilus, Lactobacillus gasseri). Thus, when the vaginal pH decreases over several days, there is a pronounced suppression of the growth of anaerobic bacteria, as well as the restoration of normal flora (Lactobacillus acidophilus, Lactobacillus gasseri).

Pharmacokinetics

It is found in the systemic circulation in small quantities and is excreted through the kidneys.

Indications for use

— Chronic or recurrent vaginitis (bacterial vaginosis, nonspecific vaginitis), caused by anaerobic flora (due to altered vaginal pH).

— To normalize the disturbed vaginal microflora.

Contraindications

- Hypersensitivity to any of the components;

— Vulvovaginal candidiasis.

Use during pregnancy and lactation

Not contraindicated during pregnancy and lactation.

Directions for use and doses

Intravaginally. 1 vaginal tablet is inserted into the vagina while lying on your back with legs slightly bent, 1 time in the evening before bed. The course of treatment is 6 days. Repeated courses of treatment are possible. If necessary, the course of therapy can be extended for a longer period.

Side effect

The drug is well tolerated. Very rarely (<1/10000) - hypersensitivity to one of the components of the drug. Rarely (< 1/100, ≥ 1/1000 cases), burning or itching in the vagina, increased mucous discharge, hyperemia, and swelling of the vulva are possible.

Overdose

Cases of overdose have not been described.

Interaction with other drugs

Salicylates stimulate the process of removing vitamin C from the body. Estrogens improve the bioavailability of vitamin C. Vitamin C reduces the activity of anticoagulants.

special instructions

The drug does not inhibit the growth of fungal flora of the vagina. Interruptions in the use of Vaginorm S due to intercyclic or menstrual bleeding are not necessary. Vitamin C changes the pattern of glucose in the urine, as well as the pattern of transaminases, lactate dehydrogenase and bilirubin in the blood serum. Manifestations such as burning and itching may be due to the presence of a concomitant asymptomatic fungal infection. Therefore, when these symptoms appear, an analysis should be performed to exclude a fungal infection.

Best before date

3 years. Do not use after the expiration date indicated on the package.

Storage conditions

In a dry place at a temperature not exceeding 25 C. Out of the reach of children!

Vacation conditions

Over the counter.

Analogues of Vaginorm S

If you are not satisfied with the prices for the drug in the pharmacy (550–950 rubles), there is no desired effect, or symptoms of intolerance to a component arise, the question is what to replace Vaginorm S with. All analogues are available in the form of suppositories (candles). The most popular and available substitutes:

• Acylact;
• Bifidumbacterin;
• Lactagel;
• Lactonorm;
• Gynoflor E;
• Vagilak;
• Lactozhinal;
• Femilex;
• Lactobacterin.

Note! Analogs of the drug differ in composition, price per package and per course, and restrictions on use. The cost of medicines depends on the markup of the selected pharmacy organization, exchange rates, remoteness of the region and other factors.

Acylact

A cheap analogue that can replace Vaginorm S suppositories based on lactobacilli. One of the features of the drug is the need for storage in the refrigerator to ensure the proper quality of the medicine. Suppositories are used after antibiotic treatment for gynecological inflammatory diseases, bacterial vaginosis, colpitis, before surgery, to prevent complications before childbirth. Cannot be used for thrush, or scientifically for vulvovaginal candidiasis.

Bifidumbacterin

A preparation based on live bifidobacteria, stored in the refrigerator. It is indicated for various vaginosis, colpitis, dysbacteriosis and inflammatory processes of the urogenital tract. It is also used as a preventive and therapeutic agent before surgery and childbirth. When used simultaneously with antibiotics, the drug has a weaker effect.

Lactagel

The analogue is tubes with gel for one-time intravaginal administration, intended to normalize the acidity of the vaginal microflora. It contains lactic acid, which ensures normal pH values ​​(it acidifies the environment), and glycogen, which is a breeding ground for beneficial bacteria. The analogue is effective for unpleasant odor, discomfort and heavy vaginal discharge.

Lactonorm

Laktonorm is an analogue of the drug Vaginorm S based on live acidophilic lactobacilli of special strains. Its advantage is that it does not favor the proliferation of Candida fungi, which cause thrush. Can be used after local antiseptics and antibiotics.

Gynoflor E

A combined product containing lactobacilli and the hormone estriol. Its use is exclusively as prescribed by a specialist for urogenital infections, STDs, disorders of the vaginal microflora with bacterial vaginosis, vulvovaginitis and inflammation in postmenopause.

Important! The choice between Vaginorm or Gynoflor E is made only by a doctor because of the hormone content in the latter medication.

Vagilak

The analogue is also based on lactobacilli. Widely used for various bacterial infections, in preparation for childbirth and to reduce the side effects of antibacterial drugs. The manufacturer Vagilak also offers women liquid soap for intimate hygiene and a moisturizing gel to maintain the health of the vaginal microflora and prevent or supplement the treatment of inflammatory and infectious diseases of the urogenital tract.

Lactozhinal

Analogous to Vaginorm S in action, but different in composition. It is based on strains of lactobacilli that improve the vaginal microflora and prevent relapses of vulvovaginal candidiasis (thrush). In case of exacerbation of the disease, it is used only in the final stage of treatment after taking antifungal and anti-inflammatory drugs.

Femilex

Suppositories are Russian substitutes for Vaginorm S, used intravaginally on the basis of lactic acid and are similar in composition to Lactagel. They are prescribed to normalize vaginal pH and improve the state of microflora, improve protective properties against genital infections and prevent the growth of pathogenic flora. The package contains 5 or 10 vaginal suppositories.

Lactobacterin

Contains lactobacilli. It is used intravaginally in the form of suppositories, lotions and applications. Stored exclusively in the refrigerator.

Prices for analogues of Vaginorm S in Moscow

Vaginorm or Acylact

When choosing between Vaginorm S and Acylact, you should decide on the goals of treatment and the main drugs. The Acylact analogue is used as the second stage after antimicrobial and antibacterial therapy. The first medication itself has an antimicrobial effect and can be prescribed simultaneously.

Advantages of Vaginorm S compared to Acylact:

• shorter course (package contains 6 suppositories, Acylact – 10 pcs.);
• simultaneous restoration of vaginal microflora and prevention of the development of anaerobic infections, their treatment;
• no need to refrigerate.

In other respects, both drugs are similar.

The same choice can be made between Vaginorm or Laktonorm.

Vagilak or Vaginorm

For frequent relapses of vaginitis and vaginosis, you can use Vagilac or Vaginorm S. The second drug should not be used when planning pregnancy, since it acidifies the vaginal environment and makes it unsuitable for sperm.

In general, the two analogues are aimed at restoring the vaginal microflora. They differ in the main component and course of application: Vaginorm C 6 days, analogue - 15 days. The cost is approximately the same.

Doctor's review

Alexander Pichugin Doctor of the highest category, Falkenstein

“Vaginorm-s is suitable for seasonal and regular use; its effect is manifested not only in eliminating allergic symptoms, but also in eliminating the causes. From the first use, it eliminates lacrimation, swelling, runny nose and nasal congestion, skin itching and rashes, cough, asthmatic attacks, shortness of breath. By using the drug in courses several times a year, you will not encounter allergies even at the peak of its aggravation. As an additional effect, the drug restores metabolic reactions, cleanses the body of toxins and waste, increases immune resistance, improves overall well-being, and increases performance. Passed clinical studies and has certificates of conformity.”

Femilex or Vaginorm

Femilex contains lactic acid, which is beneficial for restoring microflora and maintaining vaginal acidity. The course is short – 5–10 days. Can be used after treating thrush or using antibacterial drugs. The price per course is lower than that of Vaginorm S (on average 350–750 rubles).

Vaginorm C has the same effect and consists of ascorbic acid. The disadvantage is the high price of the course if the treatment is long-term, over 6 days.

When choosing a medication, you can give preference to an analogue.

Pharmacological properties of the drug Vaginorm S

Ascorbic acid lowers the pH level in the vagina, which inhibits the growth of anaerobic bacteria, which cannot reproduce at a pH of 4.0 or lower. Lactobacilli can multiply at pH ≤4.0. Thus, when the pH of the vagina decreases, the growth of anaerobic bacteria is inhibited, as well as the restoration of normal flora. On the other hand, the growth of yeasts that can proliferate at low pH is not inhibited. In vitro studies have shown that the bacteriostatic and bactericidal effects of ascorbic acid on vaginal flora are mediated primarily by a decrease in pH. A slow release of ascorbic acid is observed, with approximately 70% entering the dissolution medium over 4 hours. There is also a rapid decrease in pH of the medium from 6.8 to 4 over 30 minutes and a slow decrease by 0.72 over the next 4– x h. The maximum plasma concentration is reached after 1.5 hours, and the half-life in the terminal phase is 61 hours. Ascorbic acid enters the systemic circulation in small quantities and is excreted in the urine.

Vaginorm or Laktozhinal

Vaginorm C packaging is designed for 6 days of use, sometimes up to 2-3 weeks at a price of 550-950 rubles. An analogue costs 750–1050 rubles. for 14 capsules, which is 8 capsules more. It is used for up to 2 weeks, 1 capsule intravaginally, or the course is halved when used morning and evening.

In terms of action, Vaginorm S and its analogue are similar: they are not used for exacerbation of thrush, they improve the acidity of the vagina and normalize the microflora, and prevent the development of anaerobic infections. For chronic infectious and inflammatory processes of the urogenital tract, it is better to choose an analogue, since the course of treatment is long.

The choice of drugs that can replace Vaginorm S is best made together with a gynecologist. It is important to take into account the presence of gynecological diseases, the frequency of their relapses, and special contraindications.