Vormil is an anthelmintic drug that is used to treat diseases of a parasitic nature. The active component of the drug is albendazole.
The drug is available in dosage forms such as chewable tablets and oral suspension. In 1 tablet the concentration of the active substance is 400 mg. In addition, it also contains auxiliary components such as microcrystalline cellulose, corn starch, magnesium stearate, purified talc, sodium starch glycolate, colloidal silicon dioxide, sodium propylhydroxybenzoate, sodium methylhydroxybenzoate, mixed fruit essence and aspartame.
Wormil in suspension contains 400 mg of albendazole per 10 ml (1 bottle), as well as excipients: sucrose, sodium methylhydroxybenzoate, croscarmellose sodium, sodium propylhydroxybenzoate, mixed fruit essence, purified water, polysorbate 80, erythrosine, raspberry essence, glycerol and sodium benzoate .
Release form and composition
The drug Vormil is an anthelmintic substance and eliminates a large number of parasites in the digestive organs.
Chewable tablets consist of the following components:
albendazole;- starch;
- cellulose;
- silica;
- magnesium stearate;
- sodium;
- aspartame.
White elongated tablets without shells. The drug has a special line for convenient dosing. Available in cardboard packaging, tablets are located on a plate of 3 pieces, one plate per package.
Suspension for internal use, contains the following components:
- albendazole;
- sodium;
- sucrose;
- fruit essence;
- water.
Produced in a dark glass bottle of 10 ml, located in a cardboard package.
pharmachologic effect
The medicinal substance Vormil belongs to the group of drugs that have an anthelmintic effect on the human body. Used to eliminate all types of parasites and their eggs and larvae.
The substance blocks the metabolism of parasites and destroys cells, which leads to death.
Proper use reduces the risk of re-emergence of microorganisms and destruction of digestive organ tissue by parasites.
Pharmacodynamics
The active substance Albendazole has an effect directed against various types of harmful microorganisms in the body and belong to the type of parasites.
Giardia lamblia
The action of the substance has the same effect on both adult parasites and their larvae, blocks further reproduction and removes them naturally from the human body.
The medicinal substance effectively eliminates all types of intestinal parasites, as well as protozoa such as Giardia lamblia, is prescribed to eliminate tissue parasites and eliminate cystic formations of granular echinococcus.
Pharmacokinetics
The medicinal substance Vormil is used for internal use.
After entering the stomach, the drug is practically not absorbed and is not transported throughout the body through the circulatory system.
After use, a metabolic process is observed that passes through the liver. It tends to accumulate in the body and is partially excreted after 9 hours.
The drug begins its action a few hours after entering the digestive tract.
It is excreted from the body via the biliary tract and naturally along with feces. With long-term use, prolonged elimination may occur, which can last up to 10 days.
Interactions with other medicinal drugs and other types of interactions
Albendazole induces enzymes of the cytochrome P450 system.
With one-hour administration of cimetidine, praziquantel and dexamethasone, there may be an increase in the level of albendazole metabolites in the blood plasma, which indicates the systemic activity of the drug, which in its turn can cause overdose.
Medications that may slightly alter the effectiveness of albendazole: anti-drug drugs (eg, phenytoin, phosphenytoin, carbamazepine, phenobarbital, primidone), levomizole, ritonavir.
The effectiveness of treatment in patients should be monitored, and alternative dosage regimens or therapy may be necessary.
Grapefruit juice also increases the level of albendazole sulfoxide in blood plasma.
Due to the possible disruption of the activity of cytochrome P450, there is a theoretical risk of interaction with the following drugs: oral contraceptives, anticoagulants, oral cutaneous drugs, theophylline.
When taking albendazole and theophylline for one hour, monitor the level of theophylline in the blood.
The systemic effect increases if the drug is taken within an hour.
Indications for use
The medicinal substance Vormil is used for the following situations:
- enterobiasis;
- necatoriasis;
- strongyloidiasis;
- trichocephalosis;
- clonorchiasis;
- ascariasis;
- capillariasis;
- hookworm;
- mixed type invasion;
- trichenellosis;
- toxocariasis;
- before the procedure for eliminating cystic echinococcosis;
- Giardiasis in childhood.
The drug can be prescribed both in complex and in independent therapy to eliminate parasitic accumulations from the human body.
Showing
Intestinal forms of helminthiasis and skin syndrome Larva Migrans
(short-term treatment with small doses): enterobiasis, ankylostomiasis and necatoriasis, hymenolepiasis, teniosis, strongyloidiasis, ascariasis, trichocephalosis, clonorchiasis, opisthorchiasis,
Larva Migrans
, giardiasis in children.
Systemic helminthic infections (trival treatment with high doses):
cystic echinococosis (caused by Echinococcus granulosus
):
- in case of impossibility of surgical delivery;
- before surgical procedures;
- after surgery, if the preoperative treatment was short, to avoid the proliferation of helminths, or during the hour of surgery, living forms were found;
- after performing transcutaneous drainage of cysts for diagnostic or therapeutic purposes;
alveolar echinococosis (caused by Echinococcus multiocularis
):
- in case of inoperable illness, congestion in cases of local or distant metastases;
- after palliative surgical treatment;
- after radical surgical intervention or liver transplantation;
neurocysticercosis (caused by Taenia solium
):
- if single or multiple cysts are detected or with granulomatous lesions of the brain;
- with arachnoid or internal socket cysts;
- with racemic cysts;
capillarosis (caused by Capillaria philippinensis
), gnathostomiasis (caused by
Gnathostoma spinigerum
and related species), trichinosis (caused by
Trichinella spiralis
and
T.pseudospiralis
), toxocariasis (caused by
Toxocara canis
and related species).
Contraindications
Before starting to use the drug Vormil, you must carefully study the instructions for use.
Vormil is contraindicated:
sensitivity to the components of the drug;- pregnancy;
- breast-feeding;
- age under 2 years;
- pregravid period;
- diseases of the digestive system, which are accompanied by bleeding.
The use of a substance in the presence of contraindications can cause disruptions in the body and cause additional types of symptoms.
Dosage regimen
Vormil is recommended to be taken after eating; the tablets are chewed and swallowed, so the results are achieved much faster.
When using the substance in the form of a suspension, shake the bottle thoroughly. The dosage of the drug is determined for each patient.
The dosage regimen depends on the type of problem:
- Trichenellosis, ascariasis, hookworm, the drug is used once a day: for adults , 1 tablet (10 ml of suspension) therapy for up to 5 days;
- children : 1 tablet, course no more than 3 days.
- adults : 1 tablet for 3 days;
- children duration 5-6 days;
For other methods of treatment, the dosage is determined individually depending on the personal characteristics of the body and weight category.
If it is necessary to carry out a second course of treatment, it is necessary to wait a break of at least 14 days. The dosage is used in reduced quantities as recommended by a doctor.
Features of good stagnation
Short-term treatment of intestinal infections and skin syndrome Larva Migrans.
To help avoid taking Wormil during the early stages of gestation, women of reproductive age should be treated in the first week after menstruation or after a negative vaginity test. Reliable contraception is required throughout therapy.
Treatment with albendazole may reveal evidence of already established neurocysticercosis, especially in areas with a high rate of infection with Tenia solium
. Patients may experience neurological symptoms, such as vessels, displacement of the intracranial pressure, and focal symptoms due to a inflammatory reaction that causes the death of parasites in the brain. Symptoms may subside quickly after treatment, so it is important to begin appropriate therapy with corticosteroids and anti-drug medications.
Treatment of systemic helminthic infections was encouraged.
Treatment with albendazole is accompanied by slight or moderate shifts in the level of liver enzymes, which tend to normalize after treatment. It was reported that he was suffering from hepatitis. Therefore, the level of liver enzymes should be checked before the skin course of bathing and the last 2 hours of bathing. If the level of liver enzymes significantly increases (more than 2 times equal to the upper limit of the norm), treatment with albendazole is followed. Treatment can be renewed after normalization of enzyme levels, and the patient's condition is closely monitored.
Albendazole may cause suppression of the cerebrospinal fluid, so the patient's blood should be tested both on the scalp and on the skin over a 28-day cycle. Patients with hepatic diseases, including hepatic echinococosis, are more susceptible to suppression of the cerebrospinal fluid, resulting in pancytopenia, aplastic anemia, agranulocytosis and leukemia, and There is a need for careful monitoring of blood counts. In the event of a significant decrease in blood counts, follow the procedure (sections “Method of administration and dosage” and “Adverse reactions”).
It can be used during obligatory deworming (prevention) before vaccination, as well as for preventive treatment twice a day.
In patients with neurocysticercosis treated with albendazole, symptoms may develop (for example, strokes, displacement of the intracranial pressure and focal symptoms), associated with a fiery reaction, causing the death of parasites. This should be treated with corticosteroids and anti-seizure drugs. To prevent the onset of cerebral tension during the first stretch of treatment, it is recommended to take oral or internal corticosteroids.
To avoid stagnation of Wormil for women during the early stages of gestation, as well as for women of reproductive age, follow:
- to begin to indulge more after a negative vaginosis test;
- be aware of the need to maintain effective methods of contraception within an hour
Treat with the drug for a month after your appointment.
Treatment with albendazole may reveal evidence of already established neurocysticercosis, especially in areas with a high rate of infection with Tenia solium
. Patients may experience neurological symptoms, such as vessels, displacement of the intracranial pressure, and focal symptoms due to a inflammatory reaction that causes the death of parasites in the brain. Symptoms may subside quickly after treatment, so it is important to begin appropriate therapy with corticosteroids and anti-drug medications.
Please ensure that the drug contains sucrose. If you have an intolerance to certain herbs, consult your doctor before taking this medicine.
The presence of propylparaben sodium and methylparaben sodium in the drug may cause allergic reactions (possibly enhanced).
Suspension during pregnancy or breastfeeding.
The drug is contraindicated for use during pregnancy or breastfeeding and for bathing women who are planning to become pregnant. Before the drug starts to dry, it is necessary to wash your chest.
This has to do with the speed of the reaction when using vehicles using other mechanisms.
Based on the presence of such a side reaction, such as congestion, it is recommended that during the period of albendazole stagnation, avoid treatment with vehicles or robots with other mechanisms.
Side effects
The medicinal substance Vormil during treatment can contribute to the formation of the following side symptoms:
- From the digestive system - nausea, vomiting, abdominal discomfort, bloating, indigestion.
- From the nervous system – dizziness, headache, nervousness, sleep disturbance.
- From the hematopoietic organs – leukopenia.
- On the part of the visual system - a decrease in the level of vision, the appearance of ripples before the eyes.
- From the skin system - allergic rashes, itching and swelling of the skin.
- Others – fever, general muscle weakness, bitter taste in the mouth.
- From the respiratory system – rapid breathing, shortness of breath.
Most often, side effects go away on their own after a short time, without requiring a change in the dosage of Vormil. If adverse symptoms continue for more than 2 days, you should contact your healthcare professional to review the dosage or prescribe a different type of drug.
Overdose
When the drug Vormil is used correctly, side effects rarely occur.
However, depending on the characteristics of the patient’s body, the following symptoms may be observed:
- vomit;
- hallucinations;
- stomach ache;
- loss of consciousness.
If this type of overdose symptoms occurs, you must stop using the drug and rinse your stomach with plenty of warm water.
If symptoms do not stop, you should contact a medical facility.
special instructions
To achieve positive results during treatment with the drug Vormil, it is recommended to observe the following treatment features:
- If laboratory parameters are violated, therapy with Vormil is stopped until normal is completely restored;
- Treatment of elderly patients requires special care, especially with a reduced level of the immune system;
- During long-term therapy, it is necessary to regularly monitor the status of leukocyte counts;
- During the therapy period, the use of laxatives is not required;
- The drug Vormil is recommended for use by all family members to prevent the risk of re-infection.
Long-term use of the drug Vormil is permissible as prescribed by the attending physician, in individually determined dosages.
Side effects
On the side of the grass tract and liver:
stomatitis, dry mouth, baking, boredom, vomiting, abdominal pain, flatulence, diarrhea, constipation, transient increase in the activity of liver enzymes, diarrhea, hepatitis, hepatocellular damage.
On the side of the cardiovascular system:
arterial pressure, tachycardia.
On the side of the central nervous system and peripheral nervous system:
insomnia or drowsiness, headache, confusion, confusion, disorientation, hallucinations, seizures, decreased visual acuity.
On the side of the blood and lymphatic systems:
leukopenia; neutropenia; thrombocytopenia; anemia, including aplastic anemia; agranulocytosis, pancytopenia. Patients with liver diseases, including hepatic echinococosis, are more susceptible to suppression of the cerebrospinal fluid.
From the side of the skin and under the skin:
scalp swelling, hyperemia, polymorphic erythema, Stevens-Johnson syndrome, renal alopecia, dermatitis, pimples.
On the side of the thyroid system:
impaired function of nitric acid, hypothyroidism deficiency, proteinuria.
Allergic reactions:
hypersensitivity reactions, including huffing; sverbizh; kropiv'yanka; puffy grass; dermatitis; fever.
Zagalni discord:
pain in the hands, throat; gap; weakness.
Patients with liver disease, including hepatic echinococosis, are more vulnerable to suppression of the cerebrospinal fluid.
Drug interactions
The medicinal substance Vormil is used in complex therapy with other types of medications as prescribed by the attending physician.
The use of Vormil with dexamethasone and cimetide tends to increase the concentration of albendazole in the patient’s liver.
It is forbidden to use Vormil with other similar drugs; it can lead to an overdose and a reduced effect of the drugs on the problem.
Impact on the management of transport and mechanisms
The drug Vormil can cause dizziness, so during the treatment period you should refrain from driving.
Wormil and alcohol
The medicinal substance Vormil is not recommended for use in combination with alcoholic beverages.
Symptoms of poisoning may occur and the patient’s well-being may worsen.
Alcoholic drinks tend to reduce the effect of the active component on the problem and prevent the desired result from appearing.
Additional Information
During the course of therapy, you must carefully monitor your condition. If side effects or undesirable reactions occur, you must stop taking the drug and consult a doctor to decide whether to replace the drug with an analogue.
It is necessary to strictly monitor laboratory blood tests (liver enzymes) and if they double, stop taking the drug until they are restored. Reception should be continued immediately after the blood picture normalizes and continue to monitor their indicators.
Price
Wormil has the following costs:
- Chewable tablets – 200 rubles :
- suspension from 250 rubles .
The price of Vormil may vary depending on the area where the pharmacy kiosk is located.
Storage conditions
The medicinal substance Vormil is dispensed at the pharmacy kiosk without the need to provide a prescription. Vormil should be stored in a dark, cool place for no more than 3 years; for tablets, 2 years from the date marked on the packaging for the drug in suspension form.
Analogs
The drug substance Vormil may cause side symptoms and is not suitable for every patient.
For such cases, similar medicinal substances with similar effects on the human body can be prescribed.
- Aldazole is an anthelmintic drug produced in Ukraine. Reduces the proliferation of microorganisms that belong to the group of parasites and acts with equal effectiveness on both adults and larvae. It is prescribed for all types of parasites; it tends to accumulate in the human body and, with long-term treatment, can cause a number of side effects. Cost 130 rubles .
- Vermox is a drug produced in Romania. Eliminates most harmful organisms, which are classified as parasites. Almost completely eliminated from the body naturally during bowel movements. Prohibited for use in case of impaired functioning of the kidneys and biliary tract. Before starting therapy, it is recommended to consult with your doctor. On the first day of therapy, it may cause unpleasant symptoms of nausea and discomfort in the abdominal area, but such adverse reactions go away on their own. Cost 160 rubles .
- Zentel - the main component of the substance is albendazole. It is recommended to use the drug during meals. For children, it is recommended to use the drug in the form of a suspension, since the liquid form has a quick effect on the problem. The substance tends to cause a large number of side symptoms, therefore, before starting therapy, it is recommended to carefully study the instructions and, if possible, consult with a specialist. Cost 90 rubles .
- Nemozol is an anthelmintic drug produced in the form of one tablet on a plate. It has a high level of effectiveness in eliminating a large number of parasites in the human body. When conducting therapeutic therapy, it is recommended that all family members undergo treatment. It may cause overdose symptoms if used incorrectly; in case of such symptoms, gastric lavage should be performed and contact a medical facility. During therapy, the drug reduces the effect of oral contraceptives. Cost 190 rubles .
- Pharmox is a substance that has a mild effect on the digestive organs and blocks the proliferation of parasites. The antihelmintic effect is achieved due to the property of the substance to destroy the cell membranes of microorganisms, which leads to the death and elimination of microorganisms naturally. Can be used for patients under 2 years of age in urgent need, under the close supervision of a pediatrician. If used incorrectly, it causes a large number of side symptoms. Cost 230 rubles .
- Pyrantel is a substance that affects the muscles of parasites and leads to their temporary blocking, which prevents their normal functioning and leads to death. The greatest effectiveness of the drug is achieved on adults; to completely remove the eggs, it is recommended to undergo two courses of treatment. Used after meals, the tablet is chewed. In cases where the patient cannot chew the tablet, it can be crushed and mixed with water and consumed. Cost 60 rubles .
- Decaris - the substance has the ability to paralyze parasites and removes them from the body naturally. After using the drug, the effect is achieved within 24 hours; if necessary, therapy is recommended to be repeated after 14 days. May cause allergic reactions and stomach upset. To achieve more visible results, it is recommended to use a laxative to increase intestinal motility. Cost 210 rubles .
- Angelmin - used to eliminate all types of parasites in the digestive organs. Prescribed before a surgical procedure in the area of the digestive organs. Experts recommend stopping medical therapy before planning a pregnancy. Not suitable for long-term treatment; the effect of the substance begins 2 hours after consumption. Cost 95 rubles .
- Phytoglistocide is a medicinal substance that contains plant components. The drug not only eliminates harmful microorganisms, but also improves the condition of microflora in the digestive organs. Proper use eliminates parasites and prevents their reoccurrence. Cost 140 rubles .
Aldazole
Vermox
Zentel
Nemozol
Pharmox
Pirantel
Dekaris
Angelmin
Phytoglystocide
Drugs can have different effects on the characteristics of each organism. Therefore, before starting treatment, it is recommended to carefully study the instructions for use for possible side symptoms.
Wormil or Vermox?
The drugs Vormil and Vermox have similar effects on the human body. It is impossible to clearly identify which type of drug is better. Since each person may have individual characteristics of the body, and react to varying degrees to the constituent components of medications.
Medicines eliminate adult parasites and block further development of eggs, which leads to their natural passage during the bowel movement.
The following distinctive features are distinguished:
- drugs have different active substances, so the type of drug substance can be prescribed depending on the individual characteristics of the patient;
- Vormil can be used in the form of a suspension, which accelerates the effect of the active substance and simplifies the process of use;
- the drug Vormil eliminates parasites that form in tissues, Vermox acts only in the digestive organs;
- Vormil has a higher cost;
- Vormil is more often recommended for acute forms of diseases, while Vermox is prescribed as a prophylactic agent.
Only a specialist can correctly determine the most suitable type of drug after examining the patient.
Wormil or Nemozol?
| Wormil | Nemozol |
| Medicines have a similar effect on the problem. The same active substance can cause similar side symptoms, and there is a list of diseases that the drugs are used to eliminate. | |
| Vormil can eliminate various types of parasites, regardless of the degree of progression of their reproduction. | The drug Nemozol has weaker characteristics and is used in non-advanced stages of the disease. |
| Vormil contains fewer toxins in its composition, so it can be used for children. | Nemozol is used for patients over 6 years of age. |
| During the treatment period using Nemozol, experts recommend using contraceptives, since the substance tends to disrupt the development of the fetus. | |
| The drug Vormil is a newer substance, while Nemozol has been used in medicine for a long time, and is very often prescribed by medical staff. | |
How to take Vormil for prevention
For preventive purposes, following the instructions, you should take one Vormil tablet for three days in a row, then repeat the course after six months. However, it should be said that the medication has many side effects and can behave unpredictably, as evidenced not only by the positive reviews of people who once decided to buy Vormil at the pharmacy and entrust their health to it. There have been cases where albendazole had a negative effect even on adults.
It may be worth choosing more gentle anthelmintic drugs, considering analogues of the drug with a similar effect, but a different active component - Vermox, Zentel. There are effective herbal anthelmintic preparations, which include sage, tansy, wormwood, dried grass, oak bark, yarrow, agrimony, mint, calendula, and birch leaves.
If you don’t want to treat one thing and cripple the other, think a hundred times whether your health is worth such sacrifices, because there are very effective naturopathic remedies that can be ordered in any specialized online store with delivery by mail. They are not only able to expel parasites, but also strengthen the immune system, support the liver, and cleanse the body of toxins. Maybe it will not be so cheap, but without chemicals.
Reviews
Marina Maksimova
Gastroenterologist, Candidate of Medical Sciences and editor of articles at gastro911.com. For more than 10 years I have been helping to recover from gastrointestinal diseases.
