Nowadays, more and more people suffer from all kinds of skin diseases. Psoriasis, the so-called scaly lichen, is widespread. Specialists can prescribe quite a lot of drugs, gels and creams, since the range in modern pharmacies is wide. Many note that Akriderm provides an excellent effect in the treatment of psoriasis.
This hormonal-type ointment attracts with its numerous advantages and delicate action. It is known that the drug copes well with inflammatory processes in the dermis, eliminates almost all pathogenic microorganisms, and successfully copes with the pathogenic environment. At the same time, regenerative functions are stimulated. One course is enough to get rid of psoriasis. In this case, it is then recommended to repeat the therapy for preventive purposes in order to avoid relapse.
Pharmacodynamics and pharmacokinetics
This combination drug combines the properties of a glucocorticosteroid and an aminoglycoside antibiotic.
of leukocytes is inhibited , the rapid release of lysosomal enzymes , as well as anti-inflammatory mediators in the area of inflammation. In this case, there is inhibition of phagocytosis , a decrease in vascular-tissue permeability and the formation of inflammatory swelling.
As for gentamicin, it is a broad-spectrum antibiotic belonging to the group of aminoglycosides. It is characterized by a bactericidal effect aimed at pathogens of both primary and secondary bacterial skin infections. Its activity is especially evident against various gram-negative and a number of gram-positive bacteria. Anaerobes, fungi and are not sensitive to this substance .
Analogs and prices in Russia
The cost of the drug in Russia depends on the region of sale and the type of pharmacy chain (as a rule, it is possible to place an order at a lower cost in online pharmacies). The average price for Akriderm Genta is about 180-250 rubles. The medication has several effective analogues:
- Akriderm GK. The ointment is almost a complete analogue of Akriderm Ghent in its main components, therefore it exhibits the same therapeutic properties. The price per package of the product is 180-230 rubles.
- Ecolos S. The product contains the substances mometasone furoate and salicylic acid, which also relieve inflammation and skin itching. Price – 340-400 rubles.
- Rederm. The product is based on two components: salicylic acid and betamethasone. Thanks to these substances, the ointment has antipruritic, anti-inflammatory, antibacterial and antiallergic effects. The cost of packaging is from 100 rubles.
Indications for use
Akriderm Genta cream and ointment are prescribed for the treatment of:
- dermatitis;
- eczema;
- simple chronic lichen;
- diaper rash;
- psoriasis;
- itching.
Overdose
Over the long period of existence of all varieties of Akriderm ointment in clinical practice, there has not been a single case of overdose. This, of course, is associated only with the external use of dosage forms and their low ability to penetrate the circulatory system. But theoretically, with very long and uncontrolled use of Akriderm (especially for other purposes, for example in gynecology or in the treatment of proctitis), a chronic overdose may occur, with clinical manifestations of Itsenko-Cushing syndrome, since the active component of all types of ointment/cream is a corticosteroid (betamethasone ). If symptoms of overdose appear, it is necessary to stop using the drug, gradually reducing the dosage by reducing the area of application.
Contraindications
The use of this product is not recommended for:
- hypersensitivity to it;
- skin tuberculosis;
- manifestation of syphilis on the skin;
- chicken pox;
- herpes simplex;
- skin post-vaccination reactions;
- open wounds;
- lactation;
- children under one year of age.
More information about the drug in ointment form
Translucent ointment "Akriderm Genta", containing betamethasone, has a white or yellow color, it is often used in the treatment of dermatitis, it perfectly relieves itching, constricting blood vessels and reducing the release of inflammatory interleukins and mediators, in addition, this remedy reduces the permeability of vascular walls, inhibiting hyaluronidase activity.
Within the framework of external use of the ointment in therapeutic dosages, the absorption of the main active ingredients occurs insignificantly. The presented product in the form of an ointment may have different compositions and corresponding additional names:
- Akriderm Genta is used for bacterial infections.
- Regular Akriderm is suitable for inflammatory processes complicated by allergic reactions.
- Akriderm SK ointment is advisable to use if there is hyperkeratosis.
- "Akriderm GK" is suitable against the background of a fungal infection.
In our article we will dwell in detail on the drug "Akriderm Genta".
Side effects
Treatment with Akriderm Genta may be accompanied by: burning, irritation, dry skin, folliculitis, hypertrichosis , acne-like rashes, hypopigmentation , perioral dermatitis , allergic contact dermatitis. With prolonged application, especially under occlusive dressings, the development of skin maceration, secondary infection, skin atrophy, miliaria and purpura is possible.
The use of the drug for the treatment of children can cause systemic side effects such as: hyperglycemia, glucosuria, Cushing's syndrome, reversible inhibition of the adrenal cortex, and so on.
Compound
The chemical composition of Akriderm pharmaceutical preparations includes the following active ingredients:
| Trade name of the medicine | Chemical composition of the drug |
| Akriderm | Betamethasonum |
| Akriderm GK | Betamethasone Gentamicin Clotrimazole |
| Akriderm GENTA | Betamethasone Gentamicin |
| Akriderm SK | Betamethasone Salicylic acid (Acidum salicylici) |
Ointments differ slightly in composition from creams, due to additional substances that give the desired consistency to the medicine (creams are liquid and are better absorbed):
- Ointments, in addition to active substances, contain only petroleum jelly and/or petroleum jelly;
- Almost all creams contain many more components: nipagin (an antibacterial substance and preservative), petroleum jelly, propylene glycol, alcohol for emulsification, Trilon B and purified water.
Before starting treatment, many patients ask a dermatologist or pharmacists in pharmacies whether Akriderm is a hormonal drug or not. Since all types of the drug contain betamethasone, which is a corticosteroid, all these drugs are hormonal. But due to the fact that they are used only externally for a short period of time and under the supervision of the attending dermatologist, systemic effects on the patient’s body are practically excluded.
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Instructions for use Akriderm Genta (Method and dosage)
The instructions for the ointment state that it is used externally by applying a thin layer to damaged areas, 2 times daily. In special cases, the treatment regimen is established by the doctor, taking into account the severity of the disease. Mild forms of the disease allow the use of Akriderm Genta cream once every day.
The duration of therapy depends on tolerability and effectiveness, amounting to 2-4 weeks.
If there is no improvement for a long time, clarification of the diagnosis is required.
We use the drug correctly
Akriderm is used only as an external agent. It cannot be used internally! It is necessary to carry out therapy under the constant supervision of a doctor, since the remedy is quite strong.
Apply the composition directly to psoriatic plaques. It is recommended to do this twice throughout the day. When the disease is mild, there are no complications, you can limit yourself to even one application per day.
There is one common myth that for the best effect of the ointment, you need to insulate the area to which it was applied. This is wrong. There is no need for such insulation, since the composition was developed in such a way that the efficiency was already high, without any additional manipulations. All active components will have a targeted effect on the lesions of the dermis. When there are remnants of ointment that are poorly absorbed, you just need to carefully remove them with a napkin.
Pay attention to how to apply the product correctly. Movements should be light, massage. Do not put too much pressure on the skin. Be sure to thoroughly clean and dry your skin first. This way you will reduce the likelihood of various harmful bacteria and microorganisms entering. To soften the keratinized layers of the skin, you should use a cotton swab.
special instructions
If signs of hypersensitivity, skin irritation and other undesirable symptoms caused by the use of the drug appear, you should abandon this treatment and choose a more suitable one.
Long-term therapy, application of the product to large surface areas of the skin, use of occlusive dressings and treatment of children can lead to systemic absorption of GCS.
The drug for the treatment of small children over one year of age can be used only as prescribed and under the supervision of a doctor to avoid the development of systemic side effects. If Akriderm Genta cream is used for a long time over large areas, this can lead to inhibition of the functions of the hypothalamic-pituitary-adrenal system, the development of hypercortisolism, decreased excretion of hormone and a significant increase in intracranial pressure.
Also, prolonged application to the face can cause atrophic changes to appear more quickly than in other areas. Therefore, it is necessary to adhere to the average therapeutic course of 5 days.
The use of any form of the drug in ophthalmology is not allowed. Avoid contact of the product with the eyes and mucous membranes.
How long to use the product?
Only a specialist, precisely the doctor who is involved in the treatment, will be able to accurately determine the optimal course of therapy. This will directly depend on the course of the disease, on the total area of the affected skin, and on numerous characteristics of the body. The patient’s body’s reaction to the components of the hormonal drug is also of great importance. Sometimes treatment goes faster (if the body is susceptible to the drug), and in some cases such therapy has to be abandoned (when side effects occur, there is no reaction to the active components).
Analogs
Level 4 ATX code matches:
Rederm
Losterine
Akriderm SK
Akriderm
Akriderm GK
Elokom S
Diprosalik
Belosalik
Triderm
Kanizon Plus
Betasalik
Triacutan
Momat-S
Main analogues: Triderm and Kanizon plus.
Akriderm GK
Many patients wonder what Akriderm GK ointment helps with? In fact, the composition of the drug is not very different from the usual Akriderm, but there is another active substance that allows you to enhance the effect on some skin diseases.
In addition to the standard betamethasone, the drug contains gentamicin, as in Akriderm Genta, as well as clotrimazole. The latter substance has an antifungal effect and, accordingly, will be useful in eliminating skin diseases associated with fungal infections.
Therefore, this substance is used for diseases such as psoriasis, pemphigus, neurodermatitis, herpes, Lyell's syndrome, Dbuhring's disease, blistering dermatitis. In addition, the drug allows you to cope with diseases such as pityriasis versicolor, atopic dermatitis, and also treat dermatomycosis, regardless of the location of the skin lesion
But before eliminating the disease, it is important not only to know what Akriderm GK ointment helps with, but to consult with your doctor, who will prescribe the dosage and duration of treatment with this drug
Reviews of Akriderm Ghent
In most cases, reviews of Akriderm Genta ointment are positive and confirm its effectiveness. This drug is usually prescribed to treat various skin diseases. However, many users report that improvement occurs within just a few days.
In addition, you can find reviews about Akriderm Genta cream, when after stopping its use the symptoms of the skin disease return. As one patient reported, this situation can arise when treating seborrheic dermatitis on the face. This drug was prescribed by a doctor and helped quickly eliminate the symptoms of the disease. However, after completing the 5-day course, spots and peeling appeared on the skin of the face again.
Unfortunately, such messages are not uncommon.
Moreover, some patients say that the treatment, on the contrary, contributed to the deterioration of the skin condition, so they replaced it with another drug.
When starting to use this remedy, you need to know that Akriderm Genta is a symptomatic drug with high activity. Such treatment is unlikely to help eliminate the cause of the disease, only suppressing its manifestations. An ointment or cream quickly alleviates the patient's condition, but to treat the disease, basic treatment is necessary.
Therefore, it is not recommended to take this drug without a doctor’s prescription, especially for treating children. It is also important that combination therapy is carried out with precise dosages and a competent regimen.
Features of the ointment
Akriderm is a professional ointment for the effective treatment of psoriasis. The main active component here is the hormonal steroid betamethasone. This steroid is synthesized artificially. It has been revealed that in the vast majority of cases, the product has a delicate effect on the body, does not provoke hormonal imbalances, and does not put internal organs and systems at risk. That is why there are practically no contraindications for the use of the drug.
It is extremely important during therapy to relieve inflammation and restore damaged areas of the skin. Here are the main directions of action of Akriderm cream in the treatment of psoriasis:
- The level of vascular permeability decreases, swelling is relieved;
- Inflammation is eliminated;
- Hyperemia of the skin goes away;
- Burning, itching, as well as many other signs of the disease are significantly reduced;
- The pain syndrome goes away.
Akriderm ointment can be easily selected, taking into account the stage of development of the disease. It is very important to get advice from a competent doctor and not to self-medicate, since only the right complex therapy will help get rid of psoriasis.
Akriderm Genta price, where to buy
The price of Akriderm Ghent varies between 130-400 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Akriderm Genta ointment 0.05%+0.1% 15gAO Akrikhin
RUB 201 order - Akriderm Genta ointment 0.05%+0.1% 30g Akrikhin JSC
RUR 379 order
- Akriderm Genta cream 15gAO Akrikhin
RUB 263 order
- Akriderm Genta cream 30gAO Akrikhin
300 rub. order
Pharmacy Dialogue
- Akriderm GENTA ointment (tube 30g) Akrikhin OJSC
RUB 382 order
- Akriderm GENTA cream (tube 30g) Akrikhin OJSC
RUR 387 order
- Akriderm GENTA ointment (tube 15g) Akrikhin OJSC
RUB 247 order
- Akriderm GENTA cream (tube 15g) Akrikhin OJSC
RUB 238 order
show more
Use in pediatrics
There are no special restrictions or instructions for the treatment of skin diseases in children, therefore Akriderm Genta cream, according to the instructions, is actively used in pediatrics. However, in this case, it is necessary to pay attention to the following three rules of application:
- The minimum age of a child to include ointment in the list of medications is two years.
- Therapy should be carried out under the close supervision of a dermatologist and pediatrician. In this case, intermediate results of treatment should be recorded.
- The period of use should be shortened as much as possible due to the increased absorption of the medication into the bloodstream.
If negative side effects occur, it is necessary to stop treatment and consult a doctor to replace the drug with an analogue.
