Pharmacological properties of the drug Berocca
The pharmacological effect is determined by the complex of vitamins and minerals that make up the drug. The drug contains 7 B vitamins, vitamin C, calcium and magnesium. Vitamin B1 normalizes the activity of the heart and contributes to the normal functioning of the nervous system. Vitamin B 2 promotes tissue regeneration processes, including skin cells. Vitamin B 6 helps maintain the structure and function of bones, teeth, gums, and the normal functioning of the nervous system; affects erythropoiesis. Vitamin C (ascorbic acid) is a biological antioxidant and plays an important role in the inactivation of free radicals, increases the absorption of iron in the small intestine, affects the metabolism of folic acid and the function of leukocytes. Stimulates the formation of connective and bone tissue, normalizes capillary permeability . Calcium is involved in many physiological processes and enzyme systems; in combination with magnesium and vitamin B6 - in the process of transmitting nerve impulses. Magnesium is involved in various reactions, including protein synthesis, fatty acid metabolism, and sugar oxidation. Zinc as a catalyst activates more than 200 enzymes and is a component of many proteins, hormones, neuropeptides, hormonal receptors, and is also directly involved in the synthesis of coenzymes derived from vitamin B6. The content of vitamins in Berocca preparations has been selected for therapeutic use in conditions accompanied by a deficiency or increased need for vitamins (increased physical activity, during periods of prolonged nervous strain and stress; with poor and unbalanced nutrition (restrictive diets); in the elderly; in chronic alcoholism , nicotine addiction (in smokers), as well as when using oral contraceptives.Water-soluble vitamins do not accumulate in the body, therefore, in conditions accompanied by an increased need for vitamins and minerals, the content of the vitamin complex supplied with food may be insufficient.
Release form and composition
The Berocca® Plus vitamin and mineral complex is available in the form of tablets - effervescent, water-soluble or film-coated. The composition of both forms of release is almost identical, but has some differences.
Berocca vitamins are the best vitamins for your body.
For clarity, the list of biologically active components is presented in the table:
| Name | Effervescent tablets | Coated tablets |
| Active ingredients | ||
| Vitamin B₁ | 15 mg | 15 mg |
| Vitamin B₂ | 15 mg | 15 mg |
| Vitamin B₃ | 50 mg | 50 mg |
| Vitamin B₅ | 23 mg | 23 mg |
| Vitamin B₆ | 10 mg | 10 mg |
| Vitamin B₈ (biotin) | 0.15 mg | 0.15 mg |
| Vitamin B₉ (folic acid) | 0.4 mg | 0.4 mg |
| Vitamin B₁₂ | 0.01 mg | 0.01 mg |
| Ascorbic acid (vitamin C) | 500 mg | 500 mg |
| Calcium | 100 mg | 100 mg |
| Magnesium | 100 mg | 100 mg |
| Zinc | 10 mg | 10 mg |
| Excipients | ||
| Lactose monohydrate | — | 94.3 mg |
| Povidone K90 | — | 45 mg |
| Croscarmellose sodium | — | 44 mg |
| Talc | — | 15 mg |
| Magnesium stearate | — | 14 mg |
| Mannitol | 16.8 mg | 24.45 mg |
| Sodium bicarbonate | 840 mg | — |
| Sodium carbonate anhydrous | 60 mg | — |
| Sodium chloride | 40 mg | — |
| Citric acid anhydrous | 1700 mg | — |
| Aspartame | 25 mg | — |
| Acesulfame potassium | 20 mg | — |
| Polysorbate 60 | 0.9 mg | — |
| Sorbitol | 155.3 mg | — |
| Isomalt | 265.5 mg | — |
| Beta carotene | 40 mg | — |
The content of essential vitamins and mineral compounds in the tablets is the same; the difference lies only in the list of auxiliary components. They do not have a therapeutic or preventive effect on the body, but are used for technological purposes: they give the drug the desired shape and properties, and ensure the preservation of nutrients throughout the shelf life.
Special instructions for the use of Berocca
If allergic reactions develop, the drug should be discontinued immediately. Vitamin C may interfere with urinary glucose results, so use of vitamin C should be discontinued several days before such tests are performed. The coloring of urine yellow during use is due to the presence of vitamin B2 (riboflavin) in the drug. The drug does not contain fat-soluble vitamins. One tablet contains the maximum daily dose of vitamin B6 (pyridoxine), so do not exceed the recommended dose. One tablet contains 12.5% of the recommended daily intake of calcium and 33.3% of magnesium, however, for calcium and magnesium deficiency, using Berocca Plus alone is not enough. One Berocca Plus tablet contains 25 mg of mannitol, 94 mg of lactose monohydrate and 13.44 mg of dextrose, which corresponds to 0.02 XE and an energy value of 0.143 kcal, so the drug can be taken by patients with diabetes. The drug can be used during pregnancy and breastfeeding, subject to the recommended dosage.
Contraindications and side effects
The drug should not be taken by people diagnosed with the following pathologies:
- increased levels of calcium or magnesium in the blood;
- kidney stones and urolithiasis;
- oxalate nephropathy;
- hemochromatosis;
- deficiency of glucose-6-phosphate dehydrogenase.
In case of diseases of the digestive tract, congenital deficiency of glycomucoproteins, cobalamin malabsorption syndrome or hypersensitivity to individual components, Berocca Plus should be taken with caution. It is necessary to monitor your well-being in the first days of taking it and, if there are signs of intolerance, stop taking the pills.
The manufacturer assures that the vitamin and mineral composition does not affect the course of pregnancy or the development of the fetus or breastfed infant. But it is advisable for pregnant and lactating women to consult a gynecologist or pediatrician before starting treatment.
The drug is well tolerated, however, if you are allergic to the main or auxiliary components, skin rash, urticaria, and laryngeal edema may occur. Symptoms of flatulence, constipation or diarrhea may appear in the stomach and intestines.
Berocca drug interactions
Oral contraceptives reduce the amount of vitamin C in the body, possibly due to increased levels of ceruloplasmin. GCS increase its oxidation. Calcitonin increases the utilization of vitamin C. Salicylates inhibit active transport through the intestinal wall. Tetracycline inhibits intracellular metabolism and reabsorption of vitamin C in the renal tubules. Acetylsalicylic acid, barbiturates and tetracycline increase the excretion of vitamin C in the urine. Vitamin B6 (pyridoxine) in doses greater than 5 mg may counteract the effects of levodopa in patients with parkinsonism. However, such antagonism is not observed if levodopa is used in combination with a decarboxylase inhibitor (eg, benserazide, carbidopa). Thiosemicarbazone and fluorouracil neutralize the effect of vitamin B1. Antacids inhibit the absorption of vitamin B1. Neomycin, aminosalicylic acid and H2 receptor blockers reduce the absorption of vitamin B12. Acetylsalicylic acid reduces the absorption of ascorbic acid by approximately one third. Oral contraceptives can reduce serum levels of vitamin B12, folic acid, pyridoxine, and ascorbic acid. Some patients who take deferoxamine and vitamin C 500 mg daily may experience reversible left ventricular dysfunction.
Berocca remedy: effect on the body
As a rule, this drug is purchased in order to strengthen the immune system and replenish vitamins in the body, especially in the spring. It is available without a prescription, so many people prescribe it themselves or on the recommendation of a pharmacist. However, solving these problems is just the tip of the iceberg, and the basis for taking it is precisely the restoration of psychological health, relief from stress and prolonged nervous tension. For these purposes, the drug is often prescribed by doctors themselves, citing its high effectiveness with a fairly gentle effect on the human body.
How did the Berocca complex deserve such a loyal attitude? Reviews from doctors are based on observation of their patients who took this remedy, and indicate that it can be quite effective. After just two weeks of regularly taking effervescent tablets, many experienced noticeable improvements: energy levels increased, weakness and constant fatigue disappeared. A number of patients especially praised the Berocca remedy for getting rid of insomnia and reducing irritability during the day. Some of the conditions such as apathy, sleep disturbances, and anxiety are caused by a lack of magnesium in the body. The drug "Berocca" contains this element in an amount sufficient to increase it to the required level (100 mg). And in combination with other substances, its effect is only enhanced.
In addition, a vitamin-mineral complex can very quickly (especially effervescent tablets) compensate for the lack of necessary elements caused by an unbalanced diet, taking antibiotics and even a course of chemotherapy. It will also be useful during recovery after getting rid of alcohol and nicotine addiction, helping to return the body to a full life.
Analogs
Berocca is a quality drug. It's a stretch. You can call it an original remedy (since the dosages of vitamins are unique to the drug).
Relative analogues are such drugs as Combilipen tabs, Milgamma compositum, Pentovit and other drugs. Contains a complex of B vitamins.
Price
Berocca Plus is available without a doctor's prescription. Prices vary greatly depending on the markups of a particular pharmacy and the state of the drug market. Average prices are shown below:
- Pack of 15 effervescent tablets 683-813 rubles.
- Pack of 20 effervescent tablets 788-975 rubles.
- Pack of 15 effervescent tablets 824-1250 rubles.
- Pack of 30 coated tablets 845-1054 rubles.
You should not self-medicate. There are contraindications. Before using Berocca Plus, consult your doctor!
Mode of application
For oral administration. Effervescent tablets are pre-dissolved in a glass of water.
Typically, adult patients and children over 15 years of age are prescribed 1 tablet per day.
Course duration is 30 days. Repeated courses are carried out after consultation with a doctor.
When taking Berocca Plus in the recommended dosage, there is no evidence of a negative effect on pregnancy or the health of the child. At the same time, the drug should be taken strictly for medical reasons.
You should take into account the fact that the vitamins and minerals included in the drug pass into breast milk. That is why, due to ethical considerations, there is no data on the safety of the drug when used during lactation.
Coated tablets: features
The Berocca Plus complex has a longer and more stable effect. Reviews from those who have taken it indicate that the drug really restores the exhausted nervous system, strength appears (including physical strength), and well-being significantly improves. The course lasts 30 days, and the results last much longer. Let's see what these vitamins are capable of, according to doctors:
- stimulate metabolism in tissues (nervous and muscle);
- improve the functioning of the nervous system, provide favorable conditions for the transmission of nerve impulses to muscles;
- relieve nervous tension and irritability;
- help with insomnia, overwork and chronic fatigue.
All this is possible thanks to the replenishment of substances missing in the body, including important minerals, which Berocca vitamins fully supply it with. Reviews are numerous from both specialists and patients, and therefore deserve trust.
