Bronchorus is a mucolytic expectorant that can thin mucus and effectively remove it from the lungs. A cough reflex without sputum production - a reflex contraction of the bronchi - can lead to various complications and pathologies.
In a healthy person, the moisturizing secretion protects the mucous membrane of the respiratory organs from internal and external influences, being a vital protector of the body. Coughing with copious amounts of secretions makes breathing difficult and leads to blockage of the airways. The medication acts on the cough center, stimulating the bronchi to contract, cleanse, and push out secretions.
Release form and composition
- tablets: round, flat-cylindrical, white, chamfered (10 pieces in blister packs, 2 or 5 packs in a cardboard box);
- syrup: transparent colorless or yellowish liquid (100 ml in dark glass bottles, 1 bottle in a cardboard box, complete with or without a 5 ml measuring spoon).
Each pack also contains instructions for using Bronchorus.
1 tablet contains:
- active ingredient: ambroxol hydrochloride – 30 mg;
- auxiliary components: magnesium stearate, corn starch, lactose, talc.
1 ml of syrup contains:
- active ingredient: ambroxol hydrochloride – 3 mg;
- auxiliary components: sorbitol, propyl parahydroxybenzoate, raspberry flavor, methyl parahydroxybenzoate, sodium saccharinate dihydrate, propylene glycol, purified water.
Side effects
Does the medicine "Bronchorus" (tablets) cause allergic reactions? The instructions for use state that taking both forms of the drug in question can cause undesirable effects such as skin rash, angioedema, urticaria, anaphylactic shock and allergic dermatitis. The following reactions are also often observed:
- diarrhea, dry mucous membranes of the respiratory tract, dry mouth, constipation and vomiting;
- gastralgia, rhinorrhea and nausea;
- general weakness, exanthema, headache and dysuria.
Pharmacological properties
Pharmacodynamics
The active ingredient of Bronchorus is ambroxol, a mucolytic and expectorant with secretolytic and secretomotor effects.
Ambroxol has several mechanisms of action:
- stimulates the motor activity of the cilia of the ciliated epithelium of the bronchial mucosa (secretomotor and mucokinetic activity). Due to peristaltic contractions along the spiral of the ciliated cells of the bronchial epithelium, mucus is removed from the bronchial tree, i.e., mucociliary transport is significantly improved;
- increases the content of the mucous component in sputum, stimulates the serous cells of the glands of the bronchial mucosa, and also normalizes the disturbed ratio of the mucous and serous components of sputum;
- activates hydrolyzing enzymes and enhances the release of lysosomes from Clara cells, thereby reducing the viscosity of the secretion and its adhesive properties (secretolytic and mucolytic properties);
- increases the synthesis and secretion of surfactant (surfactant) in the alveoli and bronchi.
Due to the described mechanisms of action, ambroxol significantly reduces the viscosity of sputum and improves its discharge. It begins to act after 30 minutes, the effect lasts for 6–12 hours.
Pharmacokinetics
After oral administration, ambroxol is well absorbed. Maximum plasma concentration is reached within 2 hours after administration.
80% bound to plasma proteins. Penetrates through the blood-brain and placental barriers and is excreted in breast milk.
It is metabolized in the liver, resulting in the formation of dibromanthranilic acid and glucuronic conjugates.
Excreted from the body by the kidneys: 90% - in the form of water-soluble metabolites, 10% - unchanged.
The half-life is 7–12 hours, increases with chronic renal failure, and does not change with impaired liver function.
Mechanism of action of the drug
Do you know how Bronchorus works? The medicine we are considering is an expectorant and mucolytic drug. It has secretolytic and secretomotor properties.
The active ingredient of this drug is capable of stimulating the activity of the cilia of the ciliated epithelium, which are located on the bronchial mucosa.
As a result of spiral peristaltic contractions, all mucus is removed from the bronchial tree. It should also be said that ambroxol hydrochloride significantly improves mucociliary transport.
Contraindications
- first trimester of pregnancy;
- hypersensitivity to the components of the drug.
In addition, there are separate contraindications for each of the dosage forms of Bronchorus:
- tablets: age up to 12 years; lactose intolerance, glucose-galactose malabsorption syndrome, sucrase-isomaltase deficiency;
- syrup: hereditary fructose intolerance.
The drug should be prescribed with caution to patients with liver and/or kidney failure, gastric and duodenal ulcers, in the second and third trimesters of pregnancy and during breastfeeding.
additional information
In order for treatment with the drug “Bronchorus” to be effective, and the result to be immediate, you need to know additional information about this drug:
You should not combine the use of the suspension with any antitussives. This combination will not bring any results. The medication can have a laxative effect, since it contains sorbitol.
The suspension contains sugar, so the suspension should be administered to children with diabetes mellitus with caution. If possible, Bronchorus (syrup) should be replaced with medications similar in effect
When combined with antibiotics, you need to know that the active ingredient of the mucolytic agent enhances the effectiveness of amoxicillin, doxycycline, erythromycin and cefuroxime.
Bronchorus, instructions for use: method and dosage
Pills
Bronchorus tablets are taken orally after meals and washed down with plenty of liquid.
Recommended dosage regimen for patients over 12 years of age: 1 pc. (30 mg) 3 times a day, in the absence of the required effect, a dose of 2 pieces can be prescribed. (60 mg) 2 times a day. For the treatment of severe forms of the disease, the increased dose is maintained throughout the entire course. Duration of use – 5 days.
It is not recommended to prolong the use of Bronchorus without consulting a doctor.
Syrup
Bronchorus syrup is taken orally, during or after meals, with a sufficient (100 ml) amount of liquid, including water, tea or juice.
One scoop (or teaspoon) of syrup (5 ml) contains 15 mg of ambroxol hydrochloride.
For adult patients and children over 12 years of age, the recommended initial dose (during the first 2–3 days of treatment) is 10 ml 3 times a day, then the same dose with a frequency of administration 2 times a day or 5 ml 3 times a day . When treating severe pathologies, the initial dose is not reduced throughout the course.
For the treatment of children under 12 years of age, Bronchorus is used only in the form of syrup.
Recommended dosage regimen for children:
- 5–12 years: 5 ml or 1 measuring spoon 2–3 times a day;
- 2–5 years: 2.5 ml or 1/2 measuring spoon 3 times a day;
- up to 2 years: 2.5 ml or 1/2 measuring spoon 2 times a day.
You should not take the syrup for more than 5 days without a doctor’s advice.
The use of Bronchorus in children under 2 years of age is possible only under the supervision of a physician.
During the treatment period, the patient should be provided with plenty of fluids.
Indications and at what age is it allowed to take
The medication is prescribed for pneumonia, bronchitis, bronchial asthma with all possible complications, to eliminate and remove mucus in chronic and acute conditions of the respiratory tract.
An age limit for this drug is recommended: only children over 2 years of age are allowed to take it without a medical examination. However, in case of urgent need, syrup is still prescribed to babies under 1 year of age, after a thorough examination and under the strict supervision of a specialist throughout the entire treatment course.
special instructions
The simultaneous use of antitussives that impede the removal of sputum is contraindicated.
The syrup does not contain sugar, so it can be prescribed for diabetes mellitus, taking into account that the content of sorbitol and saccharin in 5 ml of syrup corresponds to 0.18 bread units (XE).
The sorbitol content in the syrup can cause a laxative effect in the patient.
Impact on the ability to drive vehicles and complex mechanisms
During the period of taking Bronchorus, it is recommended to be careful when operating complex mechanisms and vehicles.
Video
This video contains useful information about the causes of cough and expectorants. Dr. Komarovsky talks briefly and clearly, giving useful advice.
Cough syrup is the most convenient form of cough medicine for children. Lazolvan syrup is an original imported analogue medicine in liquid form. It is also available in other forms, and its formula has been tested and proven in medical practice for many years. There is also a known cheap Russian-made analogue of Lazolvan - Ambrobene syrup. Reviews about the medication are positive, and its tangible advantage is its low price. It is inexpensive and has a similar effect to Althea syrup, better known as Alteyka. It consists of plant components: the root itself and sugar liquid; enveloping the mucous membrane relieves inflammation and helps eliminate phlegm.
To choose the right remedy for you, consulting a doctor is the first sensible step towards recovery. When self-medicating, studying the instructions for use is a necessary condition for the safety of your health.
Write to us if this article was useful to you and what new things you learned. Which is right for you? Share your comments and be healthy!
Reviews about Bronchorus
Reviews about Bronchorus are mostly positive. Patients note its high effectiveness, accessibility and low cost.
Bronchorus syrup is often prescribed to children to treat coughs with viscous, difficult-to-discharge sputum. As parents write, the drug thins mucus and improves coughing, but does not increase bronchial secretions. Bronchorus reduces bronchial obstruction, is well tolerated and causes almost no side effects. It also has a moderate anti-inflammatory effect. When administered simultaneously with an antibiotic (for example, cefuroxime, erythromycin, doxycycline or amoxicillin), it enhances its penetration into the bronchial mucosa, thereby increasing the effect of antibacterial therapy. In addition, the syrup has a pleasant raspberry taste, so children drink it with pleasure.
There are reports in which patients note the lower effectiveness of ambroxol compared to acetylcysteine, which retains its activity not only in mucous sputum, but also in mucopurulent and purulent secretions.
Analogs
Analogues of this medicine include medicines containing ambroxol. They are available in different forms: capsules, tablets, mixture, solution, lozenges. There are several medicinal analogues that have already proven themselves: Ambroxol, Lazolvan, Ambrobene, AmbroHEXAL, Halixol, Flavamed, Medox, Ambrosan.
The following medicinal mixtures have similar medicinal properties: Gerbion, Mucaltin, Althea, Bronchipret, Prospan, Bromhexine and ACC 200 powder.
The medication can be purchased at a pharmacy without a prescription and treated independently. But! A preliminary examination and consultation with a doctor will help you complete the course of treatment effectively and quickly without possible complications.
Users say
What reviews are known about Bronchorus (tablets)? Consumers say that the advantage of the medicine is its cost. You can purchase a package of medicine by spending no more than 50 rubles. At the same time, the effectiveness of the drug, according to patients, is no lower than that of expensive analogues.
The tablets have a small diameter, which is very convenient for use. The tablet can be easily swallowed with a small amount of liquid. But the manufacturer recommends taking each pill with a glass of water to increase the effectiveness of the medicine.
Consumer reviews mention syrup along with Bronchorus tablets. This medication is intended for the treatment of children under 12 years of age. The suspension has a pleasant taste. It also has a low cost (within 100 rubles).
