Cerebrolysin solution contains a complex of peptides obtained from pig brain and auxiliary ingredients: sodium hydroxide, water for injection. One package contains 5 or 10 ampoules of 1, 2, 5 and 10 ml, and instructions for use of the drugs. Where is Cerebrolysin injected? The medical staff of the Yusupov Hospital, as prescribed by doctors, administers the drug intramuscularly or intravenously.
Neurologists prescribe Cerebrolysin and other medications after examining patients using the latest equipment from leading manufacturers. Severe cases of disease are discussed at a meeting of the Expert Council. Professors and doctors of the highest category take part in its meeting.
Description of release form and composition features
This medicine comes in the form of a clear, yellowish-brown solution that is intended for intravenous or intramuscular administration. The medicine is placed in dark glass ampoules of 1, 2, 5, 10 and 20 ml. You can also purchase 30 ml bottles at the pharmacy.
1 ml of solution contains about 215 mg of Cerebrolysin concentrate (this is a complex of specific peptides that are obtained from pig brain tissue). The list of excipients is small - in addition to the active ingredients, the solution contains only purified water for injection and sodium hydroxide.
Best before date
The release and expiration dates of Cerebrolysin are indicated on one of the sides of the cardboard packaging - right or left. The product is available in the form of an injection solution. In bottles its shelf life is 4 years, in ampoules – 5 years. Storing in the refrigerator is pointless, since it has no effect on the shelf life.
Use of the product 5-10 days before the expiration date is acceptable, but only under the supervision of the attending physician.
After opening the ampoule or bottle of solution, it should be used immediately. Residues must be disposed of.
Over time, Cerebrolysin, like all drugs, may lose some of its effectiveness and may also produce sediment (if stored improperly).
Identifying an unusable drug is a simple procedure. First of all, you need to make sure that the expiration date is appropriate. Next, inspect the solution itself. It is a transparent amber-colored liquid, without impurities or undissolved particles.
The use of expired medicine is strictly prohibited, as this may lead to complications in the functioning of some body systems.
What properties does the medicine have?
Why do experts prescribe the drug Cerebrolysin to children? Reviews from experts indicate that the medicine has many beneficial properties. The solution is a nootropic agent that contains biologically active, low-molecular-weight neuropeptides. These compounds penetrate directly into nerve cells, improving their functioning.
- The medicine activates the processes of energy metabolism and intracellular synthesis of protein components, which improves the functioning of the developing and aging brain.
- The drug prevents the formation of dangerous free radicals, protects nerve cells, and prevents the death of neurons under conditions of oxygen starvation and ischemia.
- It has been proven that this remedy improves cognitive functions and also has neurotrophic activity.
The drug "Cerebrolysin": indications for use
For children, any, even short-term, disturbances in blood circulation in the brain are dangerous. Therefore, an important point for many patients is the list of indications. In what cases is it advisable to take the drug Cerebrolysin? Why is this drug prescribed to children?
In pediatrics, this drug is widely used for various cerebrovascular disorders. Indications include mental retardation. Cerebrolysin (injections) is often prescribed to children for speech - reviews confirm that the medicine is really effective for such disorders.
Less commonly, the remedy is recommended to young patients suffering from clinical forms of hyperactivity and attention deficit. Sometimes the drug "Cerebrolysin" is used for enuresis (the dosage for children is determined individually; the medicine is effective only if urinary incontinence is associated with disturbances in the functioning of the central nervous system).
The solution is administered to adult patients in order to speed up rehabilitation after a previous ischemic stroke, encephalitis, meningitis and some other diseases.
Indications include severe forms of depression. The solution is prescribed if classical therapy with antidepressants does not give the desired result.
Naturally, there are other indications. The drug is used to treat dementia, Alzheimer's disease and other diseases that are accompanied by absent-mindedness and memory problems.
Instructions for use. Recommended Doses
How to use Cerebrolysin correctly? The dose for children is determined individually. As a rule, the daily amount is calculated according to the formula: 0.1-0.2 ml of solution per 1 kg of body weight.
If we are talking about the treatment of adult patients with strokes, damage to the nervous system, depression, dementia, then they are administered from 5 to 30 ml of solution per day.
The solution can be administered intramuscularly, but only if the dose does not exceed 5 ml. If we are talking about intravenous injections, then the maximum amount is 10 ml. In some cases, it is necessary to administer a large volume of solution (for example, 20 or 50 ml) - this is only possible through a slow intravenous infusion.
Sometimes the doctor decides to administer a large dose of medication (50 ml) once. However, in most cases, long-term therapy is more effective, in which the patient is given a small amount of the drug for 10-20 days.
Additional Information
To dilute the ampoule and intravenous drip, you need to use one of the following solutions:
- 0.9% sodium chloride solution.
- Ringer's solution.
- 5% glucose solution.
Intravenous and intramuscular administration is possible with simultaneous treatment with vitamins and medications that improve cardiac activity.
One of the most popular analogues today is the Russian drug Cerebrolysate, but the active substance here is obtained from the brain of cattle. Both of these solutions should never be used during pregnancy, but the issue of treatment during breastfeeding should be decided individually each time.
List of contraindications
Is it always advisable to prescribe Cerebrolysin to children? Reviews from experts indicate that this is a fairly powerful medicine. Nevertheless, there are not many contraindications to its use.
To begin with, it is worth saying that in pediatrics this drug is used only if there are significant indications, since there is a high probability of developing side effects. The drug is not recommended for use in the presence of epilepsy, since therapy can provoke an increase in the number of attacks.
The medicine is not prescribed to people with hypersensitivity to one or another component. Contraindications include renal failure and some other serious diseases of the excretory system. Injections are not given to women during pregnancy, as there is always a risk to the fetus.
Conditions for storing the drug in pharmacies and clinics
When storing medicines, professionals working in clinics and pharmaceutical points are guided by the standards of GOST 17768-90. Cerebrolysin is stored in its original packaging on the shelves of a display case next to other drugs of similar action.
If a defective or expired batch is detected, the product is withdrawn from sale or use and transferred to employees of special companies. They destroy medicines at landfills using special equipment.
Transportation is carried out subject to instructions for use. The ampoules are placed in plastic contour cells and only then - into packaging.
Description of side effects
Statistics show that patients tolerate treatment well in most cases. Nevertheless, the possibility of adverse reactions cannot be completely ruled out.
- Local reactions. Redness, itching and slight swelling may occur at the injection site.
- The immune system. Some patients develop allergic reactions, which are accompanied by skin itching, rash, redness, and hives.
- Mental disorders. Occasionally, the drug provokes confusion, sleep problems, and increased aggression.
- Heart and blood vessels. Some patients experience arrhythmia and rapid heartbeat immediately after the injection, which in most cases is associated with too rapid administration of the solution.
- Digestive organs. Sometimes people complain of nausea, loss of appetite, stool disorders, and dyspeptic symptoms.
It is worth noting that in most cases the above complications go away on their own. Most often, to eliminate adverse reactions, it is enough to just adjust the dose.
How much will the medicine cost?
Unfortunately, many people are faced with the need to take the medicine Cerebrolysin. The injections are certainly effective and have a positive effect on the functioning of the nervous system. But for many patients, cost is an important factor.
The price of the drug depends on the manufacturer, as well as the dose and volume of the solution. A package of ten 1 ml ampoules will cost approximately 900-1000 rubles. The cost of the same number of 2 ml ampoules ranges from 1600 to 2000 rubles. If we are talking about ampoules with a volume of 10 ml, then for 5 pieces you will have to pay about 3,000 rubles. Of course, therapy will cost a large amount, because sometimes it is necessary to use several packages to complete the full course. But the effect of the drug is worth the money spent.
Features of interaction with other drugs
In modern medicine, the Cerebrolysin solution is often used to treat children. Reviews from experts confirm that the drug really helps improve the functioning of the nervous system.
This remedy combines well with other medications, making it ideal for complex therapy. But it is worth considering that this drug is incompatible with solutions that contain lipids. For infusions, you cannot use liquid whose pH is 5.0-8.0.
If we are talking about the treatment of an adult patient, then it must be taken into account that simultaneous use of Cerebrolysin with MAO inhibitors or antidepressants can increase the degree of effect of the drugs on the body. That is why experts recommend reducing the dose of antidepressants.
special instructions
There are a number of special instructions that you should read before using the drug:
- After opening, the drug is used immediately.
- The drug must be administered slowly.
- It can be used with vitamins and drugs that improve cardiac circulation, but administration in one syringe is unacceptable.
- Amino acid solutions and Cerebrolysin should not be mixed in the same solution.
- Clinical trials showed no effect on the ability to drive or operate machinery.
- A mutually enhanced effect is possible when used together with MAO inhibitors and antidepressants. It is recommended to reduce the dose of antidepressants.
- Cerebrolysin should not be used with solutions containing lipids or pH altering media.
What can replace the drug "Cerebrolysin"? Analogues for children
Statistics show that this medicine is used quite often in modern medicine. But what to do if, for one reason or another, this drug is not suitable for the patient? Analogues of this product exist, and their choice is quite large. Below are effective substitutes.
- Doctors often prescribe Cortexin to patients. The medicine contains peptides obtained from the brain tissue of cattle. The drug is produced in the form of a powder used for the preparation of injection solutions.
- In domestic medical practice, the drug "Actovegin" is often used. It is a biogenic stimulant, which contains an extract from the blood of calves. The drug is effective for various disorders of cerebral circulation.
- The list of analogues also includes such a product as Mexidol. This medicine has antihypoxic and antioxidant properties and helps normalize blood circulation in the brain.
Despite the fact that the medications described above have similar composition and properties, it is not recommended to use them without permission. Only a doctor can select an effective and safe analogue.
How to store
It is easy to store Cerebrolysin at home. The ideal option would be a dark and dry place with a temperature no higher than +25°C. This could be a box, cabinet drawer or cabinet. The main thing is inaccessibility for children.
It is not recommended to freeze the solution or, conversely, to heat it. Sun rays and excessive artificial lighting also have a detrimental effect on the quality of the product.
Analogue drugs:
- Kwanil;
- Axotilin;
- Dendrix;
- Kemodin;
- Neuroxon.
Patient reviews of therapy
Doctors quite often prescribe the drug Cerebrolysin to patients. Injections help to cope with a lot of problems, normalize blood circulation and trophism of nerve tissue, and improve brain function.
Experts, as well as patients, speak well of this drug. The course of therapy gives good results. As already mentioned, experts often prescribe Cerebrolysin solution to children. Reviews confirm that therapy significantly improves the condition of young patients - therapy has a positive effect on the level of development. The medicine stimulates speech activity and helps cope with attention deficit disorder.
Older patients say that the first results appear after a few days. People with dementia experience clearer minds and less severe memory problems. The medicine also helps with depression.
It is worth noting that sometimes the patient needs to undergo several repeated courses to normalize the condition. If we talk about the disadvantages, then their list can only include high cost.
