How effective is Epigen gel in the treatment of papilloma: instructions for use, analogues, price of epigel

Compound

100 ml spray for topical use contains:

• glycyrrhizic acid – 0.1 g (the amount of the active component is equivalent to ammonium glycyrrhizinate);
• malic acid;
• fumaric acid;
• ascorbic acid;
• folic acid;
• propylene glycol;
• Tween 80 (polysorbate 80);
• purified water.

Composition of Epigen Labial (corresponds to gel for external use):

• ammonium glycyrrhizinate – 100 mg per 100 ml (active component concentration – 0.1%);
• Apple acid;
• fumaric acid;
• ascorbic acid;
• Polavax GP 200 (cetearyl alcohol-Peg-20 stearate);
• phenonip;
• butylated hydroxytoluene;
• flavor 195 AG;
• distilled water.

In what forms are they produced?

This medicine is presented in the form of a yellowish liquid with a specific aroma. For therapy, you need to choose the drug in the form of a spray. The gel is used for preventive purposes and to improve health.

The combined use of products has a better effect and affects the root of the problem. In addition to the spray, you can also use a gel, which is simply ideal for systematic use when taking a hygienic shower.

With the help of this product it is possible to maintain a normal balance of microflora and prevent the occurrence of such an unpleasant disease as candidiasis. A practical bottle with a convenient dispenser will make using this product even easier.

Release form

• Epigen intimate spray is presented in the form of a medicinal solution from light yellow to light brown in color, which has a characteristic odor. In pharmacy kiosks, the pharmaceutical drug can be found in 15 or 60 ml spray bottles with a nozzle for vaginal administration and an annotation.
• Epigen Intim gel (sometimes called cream in pharmacy kiosks or on thematic resources) with a concentration of the active component of 0.1%. Sold in a 250 ml container with a special dispenser for rational use.
• Epigen Labial is a cream for external local use (used primarily as a lip cream). A plastic tube with a medicine in an amount of 5 g or a sachet (a bag or pad with dry flavorings) weighing 2.5 g is placed in a cardboard package.

Is it safe to use the drug during pregnancy?

Epigen spray during pregnancy effectively protects the expectant mother from viruses and germs. The main active ingredient of the drug is practically not absorbed into the blood and has only a local effect. Thus, the possibility of a negative effect of the drug on the formation of the organs of the unborn child and his health is excluded.

If a woman suffers from chronic diseases of the gynecological organs, the use of the drug will help avoid exacerbation of the pathology.

If there is a danger of contracting a viral infection, the drug will kill viruses even before they penetrate the tissue cells of the genital organs. This will prevent the possible development of infection.

pharmachologic effect

Epigen Intim is an antiviral and immunostimulating pharmaceutical preparation based on a natural plant component - glycyrrhizic acid , which is obtained by extraction from licorice root. The active component of the drug has a complex therapeutic effect, however, first of all, its pharmacological effects on the immune system should be noted. Glycyrrhizic acid increases the number and activity of T-lymphocytes when applied topically, induces the formation of interferon , increases the concentration of immunoglobulins A and M , but reduces the concentration of IgG.

The mechanism of antiviral action is based on inhibition of replication processes in the early stages, which causes the release of the viral virion from the capsid, preventing its penetration into the cellular structures of the body. In clinical studies, it has been proven that glycyrrhizic acid inactivates herpes simplex virus types 1 and 2, herpes zoster virus (Varicella Zoster), cytomegalovirus and some other oncogenic viruses. Its effectiveness has also been confirmed against mutant strains of viruses that, during their life, have developed resistance to Acyclovir and Iodouridine .

Gel for intimate hygiene Epigen has antiviral properties, which are realized through stimulating effects on the cellular and humoral factors of the immune system. The active biological component significantly inhibits the release of kinins and the formation of prostaglandins by connective tissue cells in the pathological focus of inflammation. This is the basis for the regenerating effects of the pharmaceutical drug, manifested in improved repair of the skin and mucous membranes.

Analogue and substitutes for the active substance

There are no gels for intimate hygiene that are identical in composition. If a patient is intolerant to the components of Epigen gel, he can be recommended other products with lactic acid:

• Lactacyd Femina.
• Intimate Natural from Nivea.
• Sesderma Intimate Hygiene Gel.
• Carefree Sensitive.
• SebaMed.
• Clean Intimate.

Treatment should be supplemented with Acyclovir or Zovirax.

Indications for use

• comprehensive prevention of gynecological diseases of viral etiology, sexually transmitted diseases;
• infectious diseases caused by the human papillomavirus ;
• erosions and other pathologies of the cervix;
• treatment and prevention of genital warts ;
• as part of complex therapy in the treatment of herpes simplex virus infections types 1 and 2;
• itching, burning, dryness and other unpleasant sensations in the genital area;
• bacterial vaginosis;
• herpes zoster and infection with the Varicella Zoster virus ;
• nonspecific vulvovaginitis;
• nosological units in which the etiological factor is cytomegalovirus ;
• insufficiency of ovarian function.

Reviews about the drug

Reviews of Epigen gel are mostly positive, patients note an improvement in their general condition, relief of itching, burning and dryness in the intimate area, and also talk about the therapeutic effect of the hygiene product on viral pathologies of the genital organs.

Petrova Marina, Nalchik. “During pregnancy, I discovered condylomas on the labia, and in addition, thrush appeared. I decided to remove the tumors after giving birth and tried using Epigen gel. The result is that the warts began to fall off halfway through the bottle. In addition, I got rid of thrush with the help of this remedy.” Romanov Alexander, Petro. Morozova Galina, Moscow. “I have been using Epigen gel regularly for many years. Previously, I constantly felt itching and burning in the genital area, but now such symptoms are no longer observed. I recommend Epigen to everyone."

Skvortsova Irina, Krasnodar. “I tried to independently treat papillomas on the genitals using Epigen gel - there was no result. Then she went to the doctor and had the tumors removed mechanically. Now I use the product to consolidate the result.”

Despite all the beneficial properties of Epigen gel and numerous positive reviews, in the presence of human papillomavirus infection it is not advisable to use it as the main therapy. It is imperative to consult a doctor and treat the pathology with medication or remove it surgically.

Instructions for use (Method and dosage)

Instructions for Epigen intimate spray

The intimate spray is intended for external, intraurethral and intravaginal use. Before use, be sure to shake the container so that the medicinal solution is evenly distributed inside the container. Directly during use, the cylinder must be kept in an upright position. For external treatment of the skin and genitals, the pharmaceutical drug is applied to the entire pathological focus from a distance of 4-5 cm in 1-2 presses, which corresponds to the optimal dosage.

To administer the drug intravaginally (this is how a spray is used for cervical erosion, for example), a special nozzle with a sprayer is used, which is included in the kit. After placing the atomizer on the balloon instead of the original valve, insert it into the vagina and spray the pharmaceutical drug with 1-2 presses.

Intraurethral use of the spray by men also involves the use of a spray bottle. The drug is injected directly into the external opening of the urethra with 1-2 presses. If external treatment of the genital organs is performed, then the use of a sprayer is not necessary.

Frequency and duration of use of Epigen Intim spray

For herpesvirus infection type 1 and herpes zoster , the drug is used 6 times a day by applying directly to the pathological focus. The duration of drug treatment is usually 5 days, however, if the disease persists, therapy should be continued until all symptoms disappear completely.

For infection with herpes virus type 2 and cytomegalovirus infection, the drug is used 5 times a day for 14 days. It is recommended to combine external and intravaginal use of the drug. After the elimination of acute symptoms, active prevention of a recurrent course should be carried out by external and intravaginal use of the spray 3 times a day for 10 days.

In case of papillomavirus infection, treatment with a pharmaceutical drug is carried out through surgical procedures. Before removing condylomas, etiotropic therapy involves applying the spray three times throughout the day. Against the background of destruction (the method of surgical intervention is not taken into account), the drug is used five times for 10 days or more. The criterion for completing medicinal sanitation is complete healing of the pathological focus. In order to prevent immediate relapses, the spray is applied 3 times a day for 1 month.

In the long-term prevention of human papillomavirus infection, the use of a pharmaceutical drug is determined by the appearance of various provoking factors, which can be stress, respiratory viral diseases, taking antibiotics or cytostatics, microflora disturbances, and prolonged fatigue. The drug is used before and after sexual intercourse or 3 times a day during the entire period of influence of external factors of aggression.

Epigen spray for thrush , vulvovaginal candidiasis, nonspecific vulvovaginitis or its bacterial etiology is used intravaginally 3-4 times a day for 7-10 days. The therapeutic course should be repeated after 10 days, since the causative agents of these pathological conditions are able to avoid the influence of the pharmaceutical drug due to individual characteristics.

If any provoking factors appear (see above), then the thrush spray is applied 3 times a day externally and intravaginally until the harmful factors cease their effect.

The spray during pregnancy and breastfeeding should be used according to standard conservative therapy regimens, since the pharmaceutical drug is intended for local action on pathological microflora and enters the systemic bloodstream only in trace concentrations, which does not have an adverse effect on the body of the child or mother.

Instructions for Epigen gel

As a rule, the cream is used for intimate hygiene , and not for therapeutic purposes. The method of using it is to apply it externally to the genitals, after which it should be foamed and rinsed thoroughly with warm running water. The natural ingredients in the base of the cosmetic product allow you to repeat the procedure several times a day.

The gel can also be used for prevention against thrush , since glycyrrhizic acid normalizes the acidity of the intimate areas, cleanses the skin and maintains the natural microflora of the mucous membranes of the genital organs.
Daily use of intimate hygiene gel helps prevent damage by fungal cultures and avoid the very unpleasant discomfort associated with the problem of thrush.

Properties

One of the few remedies that can be used by expectant mothers for treatment is Epigen spray. Moreover, the product is approved for use throughout the entire period of gestation. There is no prohibition on the use of the spray even in the early stages, when the fetus does not yet have reliable protection in the form of the placental barrier.

Active substance

The main component of this drug is a substance of plant origin with an unpronounceable name - glycyrrhizic acid. The raw materials for its production are the rhizomes of licorice. The plant has medicinal properties and stimulates the synthesis of its own interferons in the body. The product is most effective in the fight against viruses.

Glycyrrhizic acid has the mildest and most delicate effect on the mucous membranes, so using Epigen Intim spray does not cause discomfort. Moreover, the drug helps relieve inflammatory processes and tissue regeneration.

Advice! Epigen Intim spray exhibits the greatest activity against cytomegalovirus, herpes viruses and human papilloma.

An important property of the described drug is that it acts locally without entering the bloodstream. It is for this reason that the product is allowed to be used even during pregnancy. Epigen Intim spray, if used correctly, cannot have a negative effect on the developing fetus. Mechanism of action of the drug:

• stops the uncontrolled reproduction of pathogenic microflora in the early stages of the disease;
• removes extracellular forms of the virus from the outer shells, reducing the risk of infection of healthy cells;
• increases local immunity;
• effectively relieves itching and inflammation, which often accompany genital diseases.

Interaction

Glycyrrhizic acid has synergistic pharmacological effects with other pharmaceutical antiviral drugs , in particular with derivatives of Acyclovir , Iodouridine , Interferon and some immunomodulators.

Drug interactions with basic medications used to treat these pathological conditions and nosological units (for example, antibiotics , antiseptics or painkillers) were not identified during clinical studies.

How to use?

The duration of the course of use and dosage are prescribed by the doctor individually. The choice of treatment regimen is influenced by the following factors:

• treatment of a disease is required or the drug is prescribed for prevention;
• type of pathogen - viruses, fungi or bacteria;
• degree of severity of symptoms.

Advice! If the disease is mild, then the spray can be used as the main treatment. If the disease is advanced, then a complex of remedies will be required.

Epigen analogs

Level 4 ATX code matches:
Aldara

Viru-Merz Serol

Zovirax Duo-Active

Acyclovir

Fenistil Pencivir

Bonafton

Zovirax

Atsik

Alpizarin

Herpferon

Lysozyme

Gerpevir

Kondilin

Virolex

Gevisosh

Analogs of Epigen Intim spray are presented in various pharmaceutical forms from tablets for oral use to granules for preparing a medicinal solution. If there are contraindications to Epigen spray, Glyciram , Glycyrrhizic acid or Epigen Labial are prescribed. The price of analogues of the Epigen intimate spray at licensed points of sale is, as a rule, lower, but the effectiveness of such therapeutic agents is relative, because they realize their beneficial properties indirectly, unlike a spray that acts directly on the pathological focus of the disease.

Epigen intimate gel also has its analogues on the pharmaceutical market, but the proven therapeutic properties of the licorice root extract and effects such as normalizing acidity and maintaining the physiological level of microflora of the genital organs predispose you to choose Epigen gel.

Who should not use it?

The instructions give the only contraindication to the use of Epigen Intim spray - these are the individual reactions of the body. In this case, local and systemic allergic reactions may develop. In rare cases, after using the spray, the development of urticaria, a small rash of an allergic nature, is observed.

Since the likelihood of developing an allergy increases during pregnancy, it is necessary to do a test test. To do this, it will be enough to spray a little spray on the skin of the wrist, and then observe the skin’s reaction throughout the day.

If during this time no redness, rash or other negative reaction appears on the skin, then the spray can be used for treatment and prevention. If there are signs of irritation on the skin, you need to consult a doctor to choose another drug for treatment.

Reviews about Epigen

Reviews of Epigen Intim spray characterize the pharmaceutical drug on the positive side. Patients with various infectious diseases of viral etiology recommend the drug on thematic forums and Internet resources, because the spray allows you to eliminate the pathological focus of the nosological unit and normalize the functioning of the genital organs and skin. For thrush, the medicine allows you not only to get rid of unpleasant discomfort and odor, but also to avoid this problem in the future, since the intimate gel effectively prevents this disease.

The anti-condylomas spray, in combination with surgical treatment, completely neutralizes the human papillomavirus, which ensures rapid healing of the skin defect and the fight against further relapses. The spray for HPV activates the humoral and cellular immunity, allowing you to further recognize the structure of the pathological agent and eliminate possible re-infection.

The pharmaceutical drug also helps with bacterial and nonspecific inflammatory diseases of the genital organs. An intimate spray allows you to maintain a physiological level of acidity, providing a feeling of cleanliness and freshness. Thanks to the drug Epigen intimate, the genital area of ​​both partners is protected from unpleasant consequences in the form of irritation, redness or other natural reactions.

Reviews from doctors are based primarily on the pharmacological effects and duration of the course of conservative therapy. Both indicators of a drug in the form of a spray allow us to give professional and qualified preference, based on reliable clinical studies, to this drug. On thematic resources, some medical professionals even openly admit about the independent use of Epigen Intim, which cannot but tip the scales in favor of the medicinal spray.

Separately, it should be noted reviews of Epigen Intim gel, which is often used incorrectly. The cream is designed to keep the genitals clean during daily intimate hygiene, unlike a spray. Of course, both pharmaceutical forms of the drug are based on licorice root extract, but the gel has a milder effect. The absence of soap and some other auxiliary components allows the gel to be used exclusively for cosmetic purposes.

This dosage form receives good recommendations from women who are carrying a child. Gel during pregnancy allows you to avoid a large number of aesthetic consequences of this physiological process, caused by changes in hormonal levels and some other features of the female body. The chemical formula of Epigen cream is specially designed for daily care, which in practice is manifested by the absence of dryness and various types of irritation after its use.

The price of the intimate gel is indicated below, but it is worth noting that among hygiene products it is the best, because it contains a plant with therapeutic properties. Licorice root has long been used for medicinal and cosmetic purposes, which creates a certain level of trust in this pharmaceutical drug, which is why women tend to choose an experienced method of daily intimate hygiene.

Treatment with Epigen spray during pregnancy

During pregnancy, a woman's body is exposed to increased stress. Against this background, the immune system of the expectant mother becomes weaker, its protective functions decrease. Pathogenic microorganisms, fungi, viruses can have a negative impact on the health of the woman and the fetus, so additional protection is necessary. Epigen spray during pregnancy helps solve this problem.

The drug successfully stops the proliferation of microbes that have entered the woman’s body, thereby protecting the fetus. To avoid complications, you need to know the mechanism of action of the drug and the rules for its use.

Epigen Intim price, where to buy

The pharmaceutical drug cannot be classified as cheap, but the evidence of therapeutic effects and production in Spain is really worth the money. In the Russian Federation, the price of Epigen Intim spray starts at 600 rubles - for such a minimum price a 15 ml bottle is purchased. You can buy a spray in a 60 ml bottle for between 1100 and 1500 rubles - this form of the drug may be required, for example, for thrush due to a decrease in the body’s own immune parameters. In St. Petersburg, the drug is distributed by the Ozerki Pharmacy - intimate hygiene gel can be purchased from the distributor for an average of 650 rubles.

The price of Epigen intimate spray in other post-Soviet countries may vary not only from the form and quantity of the drug, but also from the place of purchase, since some pharmacy chains enter into individual contracts with foreign suppliers. Ukraine demonstrates this situation: in first place is Dnepropetrovsk, where a 60 ml cylinder can be purchased for 400 hryvnia. Next comes Kharkov - the price of a spray for intimate hygiene is 460-480 hryvnia, and you can buy a spray in Kyiv for 500 hryvnia. The price of Epigen Intim gel is the same throughout almost the entire country and is about 300-350 hryvnia.

In Belarus, a medicinal spray with a capacity of 15 ml can be purchased for 370,000 BYN. rubles The price of intimate hygiene gel is almost 2 times less and in Minsk is about 170,000 BYN. rubles Such a large difference in the cost of various pharmaceutical forms of Epigen Intim is justified by the scope of application, because the gel is used mainly for everyday hygiene procedures, and the spray is prescribed for therapeutic purposes by qualified medical specialists.

You should find out how much a medicine costs in Kazakhstan yourself, since there is no reliable data provided by licensed points of sale.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Epigen intimate gel 250mlCHEMIGROUP FRANCE
  RUR 1,081 order
• Epigen Intim spray for local use. and outside approx. 0.1% 60ml Cheminova/B. Brown Medical S.A.

  RUB 2,433 order

• Epigen Intim spray for local use. and outside approx. 0.1% 15ml Cheminova/B. Brown Medical S.A.

  RUB 1,223 order

Pharmacy Dialogue

• Epigen Intim gel for intimate hygiene 250ml Cheminova

  RUB 1,351 order

• Epigen Intim spray 0.1% 15mlB.Braun

  RUB 1,244 order

• Epigen Intim spray 60mlB.Braun

  RUB 2,452 order

show more

PaniPharmacy

• Epigen intimate gel 250ml Ukraine, Heminova
  404 UAH. order

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Indications and contraindications

The drug can be the main remedy in the treatment of mild infections, and can also be used for preventive purposes. In difficult cases, Epigen spray acts as an element of complex therapy. It combines well with other antiviral agents, increasing their effectiveness.

In what cases should Epigen be used?

Epigen Intim spray has a wide range of indications for use. The drug is effective for viral diseases such as:

• inflammatory lesions of the genitals by the herpes simplex virus;
• vulvovaginitis caused by human papillomavirus;
• inflammation of the vulva and vagina due to cytomegalovirus infection.

In addition, the medicine is prescribed in the following cases:

• bacterial infections caused by pathogenic and opportunistic microorganisms;
• fungal infections - vulvovaginal candidiasis, thrush;
• nonspecific colpitis.

The wide range of indications is explained not only by the antimicrobial activity of the drug, but also by its ability to have a beneficial effect on local immunity. The spray eliminates the phenomena of vaginal dysbiosis and improves capillary blood circulation.

The drug has a symptomatic effect, relieving many unpleasant sensations, the woman’s well-being and mood are significantly improved. Epigen spray is also used for preventive purposes.

What can be replaced

If the expectant mother develops bacterial and viral infections of the genital area, other drugs may be prescribed. The choice of a specific medication depends on the diagnosis and the extent of the damage. Thus, herpes and herpes zoster are successfully treated with Acyclovir, fungal infections with Terzhinan, and daily care of the intimate area can be carried out with Lactacid.

Table: options for replacing Epigen during pregnancy

Photo gallery: drugs that a doctor can use to replace the prescription of Epigen Intim spray

Lactacid - a cosmetic product for daily intimate hygiene Terzhinan - vaginal tablets with antibacterial, antifungal and anti-inflammatory effects for topical use Acyclovir - an antiviral drug with a highly selective effect on herpes viruses