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Manufacturers: Krewel Meuselbach GmbH
Active ingredients
- Ivy leaf extract
Disease class
- Acute upper respiratory tract infection of multiple and unspecified localization
- Bronchitis, not specified as acute or chronic
- Chronic bronchitis, unspecified
- Sputum
Clinical and pharmacological group
- Not indicated. See instructions
Pharmacological action
- Mucolytic
- Expectorant
- Antispasmodic
Pharmacological group
- Secretolytics and stimulants of motor function of the respiratory tract
Release form and composition
Gedelix is available in the following dosage forms:
- Drops for oral administration: a brownish transparent liquid with an aromatic odor, at the bottom of the bottle after long-term storage a sediment may form, causing the drug to become cloudy when shaken (50 ml in dark glass dropper bottles, 1 bottle in a cardboard box);
- Syrup: a thick liquid from yellow-brown to yellow with a peculiar odor, the drug may become cloudy and sediment may form (100 ml in dark glass dropper bottles or bottles, 1 bottle in a cardboard box complete with a measuring spoon (spoon)).
100 ml drops contain:
- Active ingredient: ivy leaf extract (2.2-2.9:1) – 4 g;
- Auxiliary components: propylene glycol – 83.69 g; glycerol – 20 g; peppermint oil – 0.03 g; flavoring (100 g contains: star anise oil - 47.95 g; levomenthol - 27.4 g; eucalyptus oil - 24.65 g) - 0.13 g.
100 ml of syrup contains:
- Active ingredient: ivy leaf extract (2.2-2.9:1) – 0.8 g;
- Auxiliary components: hyaetellose – 0.15 g; propylene glycol – 13.877 g; macrogol glyceryl hydroxystearate – 0.5 g; star anise fruit oil – 0.015 g; glycerol – 10 g; 70% sorbitol solution (non-crystallizing) – 50 g; purified water – 39.9605 g.
Contraindications to the use of Gedelix
syrup Hypersensitivity to the components of the drug; with argininosuccinate synthetase deficiency (metabolic disorder in the urea cycle); with hereditary fructose intolerance; children under 1 year of age. Drops for oral use Hypersensitivity to the components of the drug; BA; deficiency of argininosuccinate synthetase in the body (metabolic disorder in the urea cycle); tendency to laryngospasm; children under 2 years of age (due to the presence of menthol, peppermint oil, eucalyptus oil).
Contraindications
- Arginine succinate synthetase deficiency;
- Hypersensitivity to the components of the drug.
Additionally, contraindications to the use of Gedelix in the form of drops are:
- Predisposition to laryngospasm;
- Bronchial asthma;
- Age up to 2 years.
The drug in syrup form is not prescribed to patients with hereditary fructose intolerance.
Breastfeeding and pregnant women are not recommended to use Gedelix (due to insufficient clinical data).
Pharmacological properties of the drug Gedelix
Gedelix is a herbal medicine containing an extract of thick ivy leaves, the therapeutic effect of which for inflammatory diseases of the respiratory tract is based on the secretolytic, mucolytic and antispasmodic action of glycosidic saponins contained in ivy leaves. The most valuable component of the drug are saponins from the group of triterpene glycosides; Hederasaponin C (Hederacoside C) dominates in quantity. When using the drug, mucus becomes less frequent, expectoration becomes easier, breathing improves, and irritating cough decreases. Pharmacokinetics have not been studied.
Directions for use and dosage
Gedelix is taken orally after meals.
Unless the doctor has prescribed another regimen, Gedelix in the form of drops should be taken 3 times a day in the following doses (single/daily dose):
- Adults and children over 10 years old – 31/93 drops;
- Children 4-10 years old – 21/63 drops;
- Children 2-4 years old – 16/48 drops.
Drops should be taken undiluted with a sufficient amount of water (up to 200-250 ml). The bottle with the drug should be shaken before use.
Unless the doctor has prescribed another regimen, Gedelix in syrup form is taken in the following doses (single/daily dose):
- Adults and children over 10 years old – 5/15 ml, dosage frequency – 3 times a day;
- Children 4-10 years old – 2.5/10 ml, frequency of administration – 4 times a day;
- Children 1-4 years old – 2.5/7.5 ml, frequency of administration – 3 times a day;
- Children under 1 year – 2.5/2.5 ml, frequency of administration – 1 time per day.
The package with the drug contains a measuring spoon corresponding to 5 ml.
It is recommended that adolescents and adults take the syrup undiluted. For small children and infants, the drug should be diluted with a small amount of water.
The duration of taking Gedelix is determined by the severity of the disease. The therapeutic course should not be less than 7 days. It is recommended to continue taking the drug for another 2-3 days after the symptoms of the disease disappear.
Use of Gedelix
The syrup should be used undiluted, regardless of meals. Infants and children are recommended to give the drug diluted in fruit juice or tea. The syrup is taken 3-4 times a day.
Age group | Number of appointments per day | Single dose, ml | Maximum daily dose of active ingredient, mg |
| Adults and children over 10 years old | 3 | 5 | 300 |
| Children aged 4–10 years | 4 | 2,5 | 200 |
| Children aged 1 to 4 years | 3 | 2,5 | 150 |
The Gedelix cough syrup package contains a measuring spoon, which corresponds to 5 ml and has divisions of “1/4”, “1/2” and “3/4”, which corresponds to 1.25 ml, 2.50 ml and 3.75 ml. Drops for oral use The drug should be taken undiluted, regardless of meals, with a sufficient amount of water. It is recommended that children be given the drug diluted in fruit juice or tea. Drops are taken 3 times a day.
Age group | Single dose, cap. | Frequency of application, once/day. | Daily dose, cap. |
| Adults and children over 10 years old | 31 | 3 | 93 |
| Children aged 4–10 years | 21 | 3 | 63 |
| Children aged 2–4 years | 16 | 3 | 48 |
The duration of use depends on the severity of the disease, but even with mild respiratory tract disease, treatment with the drug must be carried out for at least one week. After the symptoms of the disease disappear, treatment should be continued for another 2-3 days.
Special instructions for the use of Gedelix
Syrup Can be used by patients with diabetes, 5 ml of syrup contains 1.75 g of sorbitol (corresponding to 0.44 g of fructose), which corresponds to approximately 0.15 XE (bread units). Sorbitol may have a slight laxative effect. Drops for oral use Since the drug does not contain alcohol and sugar, it can be used by patients with diabetes. If there is no improvement in the patient's condition, if there are attacks of suffocation, purulent sputum, or increased body temperature, it is necessary to immediately consult a doctor. Use during pregnancy and lactation. The drug is not recommended for use during pregnancy and breastfeeding (due to insufficient clinical data). Children. The drug for oral use in the form of drops without alcohol should not be used in children under 2 years of age. The ability to influence the reaction speed when driving vehicles and other mechanisms. The use is possible because the drug does not contain alcohol.
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** The Drug Directory is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; Before starting to use Gedelix, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace medical advice and cannot serve as a guarantee of the positive effect of the drug.
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Hedelix oral drops
Instructions for medical use of the drug
Description of pharmacological action
Herbal product. Has anti-inflammatory, wound-healing, antioxidant effects. Saponins exhibit antibacterial and antifungal activity. Triterpenoids alpha-hederin, hederosaponins have antispasmodic, mucolytic and expectorant effects. Flavonoids (rutin, kaempferol derivatives) improve microcirculation, exhibit hepato- and nephroprotective properties, increase diuresis, and promote the excretion of uric acid salts.
Indications for use
As an expectorant for infectious and inflammatory diseases of the upper respiratory tract and bronchi with difficult to separate sputum.
Release form
drops for oral administration; dark glass dropper bottle 50 ml box (box) 1
Pharmacokinetics
The pharmacokinetics and bioavailability of the drug have not been studied.
Use during pregnancy
Should not be used during pregnancy and breastfeeding (due to insufficient clinical data).
Contraindications for use
- hypersensitivity to the components of the drug; - deficiency of arginine succinate synthetase; - hereditary fructose intolerance.
Side effects
Allergic reactions, nausea, and, in rare cases, pain in the epigastric region are possible.
Directions for use and doses
Orally, after meals, for adults and older children - undiluted; for young children and infants - diluted with a small amount of water. Adults and children over 10 years old - 5 ml 3 times a day, children 4-10 years old - 2.5 ml 4 times a day, children 1-4 years old - 2.5 ml 3 times a day, children under 1 years - 2.5 ml once a day. The duration of use depends on the type and severity of the disease, but not less than 1 week; It is recommended to continue treatment for 2–3 days after the symptoms of the disease disappear. It is acceptable to use cloudy solutions.
Overdose
Symptoms: possible nausea, vomiting, diarrhea, gastroenteritis, which is explained by the content of saponins in the drug. Treatment: drug withdrawal, symptomatic therapy.
Interactions with other drugs
Should not be taken simultaneously with antitussive drugs, because this makes it difficult to clear liquefied sputum.
Special instructions for use
If the patient’s condition does not improve, or if there are attacks of suffocation, purulent sputum, or if the temperature rises, you should immediately consult a doctor. Since Gedelix does not contain sugar, it can be used by patients with diabetes. 5 ml of syrup (1 measuring spoon) contains 1.75 g of sorbitol (0.15 XE).
Storage conditions
In a place protected from light, at a temperature of 5–25 °C. Cloudiness of the drug or the formation of sediment that formed during storage during the shelf life does not reduce the activity of the drug and is not an obstacle to its use.
Best before date
48 months
ATX classification:
R Respiratory system
R05 Medicines used for coughs and colds
R05C Expectorants (except combinations with antitussives)
R05CA Expectorants
