Instructions for use of collagen hemostatic sponge for nosebleeds or dentistry

Hemostatic sponge

The detailed instructions indicate that this pharmaceutical product simultaneously combines the functions of a sorbent and an antiseptic and helps to avoid bacterial infection of open wounds. The composition of this drug is natural, so the only contraindication for use is the body’s hypersensitivity to the active substances. The mechanism of action of a hemostatic sponge is approximately as follows: upon contact with a damaged surface, platelet adhesion and aggregation occurs, as a result of which bleeding stops.

Compound

The collagen hemostatic sponge is made from a special collagen solution extracted from the tendons and skin of cattle. Auxiliary components in the natural composition of this medicinal product for external use are boric acid, nitrofural and furatsilin. This unique composition does not dissolve in organic solvents, is integral in water, but at the same time is productively absorbed into the wound, forming a so-called protective barrier. The hemostatic sponge is resistant to elevated temperatures up to 75 degrees.

pharmachologic effect

In terms of its pharmacological properties, this medical product has no analogues in its natural composition and is sold in every pharmacy. The hemostatic sponge not only prevents bleeding and large-scale blood loss, but also restores the integrity of damaged vessels and accelerates the process of restoration of damaged epidermal tissue. This universal remedy has bactericidal, aseptic, antimicrobial, regenerating, tonic and sorbing properties, and has a targeted effect on the source of pathology.

Release form

Essentially, it is a pressed yellow powder mass that has a mild odor of acetic acid. It dissolves in the body over 4-6 weeks, while the active substances overcome the systemic blood flow and maintain their concentration for several days. The hemostatic sponge productively absorbs biological fluids, slightly increasing in size and swelling. The dimensions of such a plate are 50x50 mm or 90x90 mm, packed in a plastic bag with cardboard packaging on top.

Indications for use

The hemostatic sponge stops heavy bleeding of parenchymal, alveolar and capillary origin. This medicine must be used immediately, without waiting for heavy blood loss. You must act according to the instructions included in the package. The attending physician strongly recommends using such a pharmaceutical product for its intended purpose in the following clinical pictures, without violating the method of use, daily doses, general advice:

• mechanical or chemical damage to the integrity of the skin;
• defects of parenchymal organs, as an option - liver, gall bladder;
• trophic ulcers of different localization;
• hemorrhages of the sinuses of the dura mater;
• progressive bedsores, open wounds;
• nosebleeds of unknown etiology;
• acute otitis;
• inflammation of internal and external hemorrhoids;
• closure of the gallbladder bed after cholecystectomy;
• progressive hemostasis of dental practice.

Biological dressing Digestol

Biological dressing "Digestol" - Self-absorbing collagen wound coverings with a cleansing and antibacterial effect, are highly porous white or cream-colored plates with a specific odor, made from a mixture of natural collagen biopolymer and trypsin-like enzymes digestase and collagenase (from the hepatopancreas of the Kamchatka crab). Ingredients: collagen at least 80%, digestase enzyme (collagenase) at least 1%, purified water Area of ​​application: Complex treatment of purulent wounds, trophic ulcers, treatment of infectious and inflammatory diseases of the oral cavity, complications of diabetic foot syndrome. It has a rapid hemostatic effect by stimulating platelet aggregation and an antimicrobial effect by destroying the walls of bacteria. For the complex treatment of purulent wounds, burns, trophic ulcers, bedsores, gunshot wounds, treatment of infectious and inflammatory diseases of the oral cavity, complications of the “diabetic foot” syndrome in surgery, tamponing of sockets in dentistry. Has a cleansing and antibacterial effect. It has a rapid hemostatic effect by stimulating platelet aggregation and an antimicrobial effect by destroying the walls of bacteria. Dimensions 100x100x5 No. 1, 50x50x5 No. 1, 10x10x5 No. 10. pH of the aqueous extract: 5.0-7.5 Sterile, single use Sterilization: radiation Guaranteed shelf life of the plates from the date of sterilization: 3 years. Manufacturer: ZAO “Zelenaya Dubrava” , Russia Price: on request

Hemostatic sponge - instructions for use

This medication is intended for external use to pack an open wound. The dry substance-solution is applied over the open wound, then wait a few minutes. During this time, the hemostatic sponge fills with blood and the bleeding stops. Its edges fit tightly to the wound, but for greater reliability it is better to use a second sponge on top of the first. When the hemorrhage has stopped, the treatment agent is fixed with a U-shaped suture and a bandage is applied. To enhance the effect, the sponge must be moistened with thrombin solution.

If you use a hemostatic sponge with Ambien, the rules for use are somewhat different. The contents of the bottle are intended for tamponing the cavity of an open wound, and the product itself must be held with a surgical instrument and a gauze swab for 5 minutes. You can leave a layer of gauze in the wound for a short period of time, but it must be removed the next day. A hemostatic sponge after tooth extraction is used exactly according to this principle. The attending physician will advise you on the correct choice of prescription and intensive therapy regimen.

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Side effects

Not all patients are allowed to stop bleeding using a hemostatic sponge, since side effects may occur in the form of allergic, local reactions on the skin. This is itching, burning, redness, increased swelling of the dermis. Therefore, if the body is hypersensitive to the active substances, it is better not to use the drug after surgery and during intensive care. In addition, doctors do not exclude the risk of secondary infection. Detailed instructions for using the hemostatic sponge do not report other side effects.

Contraindications

If the surface of the dermis is damaged, not all patients are allowed to use this inexpensive drug, since there are medical restrictions. For example, in case of arterial bleeding from large vessels after resection, it is better not to use a hemostatic sponge. This drug should be prescribed to a child with caution, but it is strictly prohibited if the body is hypersensitive to the active components. So dissolving the product in the cavity of an open wound does not help all patients, as stated in the detailed instructions.

Storage conditions

The sponge must be stored in a dry place, since with high humidity this medicine will soon become unusable. The instructions say that such a local antiseptic should not fall into the hands of children or be used for other purposes. Self-medication is possible, especially if you immediately need to stop heavy bleeding. There is an expiration date written on the packaging, which is also important not to violate, otherwise you may not get the desired result. The family first aid kit is the best place to store a hemostatic sponge.

Dental sponge

Dental sponge "Stimul Oss" with chlorhexidine based on hydroxyapatite and collagen is used for filling bone defects and intraosseous implantation, for contour osteoplasty, in the surgical treatment of periodontitis, periodontal disease, etc.

The dental hemostatic sponge “Stimul Oss” is unique. The collagen sponge, in contact with the wound surface, stimulates the growth of connective tissue, i.e. wound healing. Designed to optimize reparative osteogenesis, prevent jaw atrophy after removal of teeth, cysts, benign tumors, sequestration, as well as increasing bone volume (contour osteoplasty) in order to eliminate its deformation and prepare the mouth for prosthetics. It is also used for intraosseous implantation of supports for dentures and surgical treatment of periodontitis and periodontal disease. Dental sponge “Stimul Oss” is a dry porous material with a base in the shape of a circle or square, soft elastic consistency, white color, diameter 11 mm, welding temperature in water is not less than 45.0 ° C; pH of aqueous extract 5.0–7.5; sorption activity no more than 10 minutes; mass fraction of moisture no more than 18.0% Contains: hydroxyapatite, chlorhexidine, formaldehyde. Hydroxylapatite, which is part of the drug, has a stimulating effect on the activity of reparative osteogenesis in the socket of the extracted tooth. Chlorhexidine is introduced to increase antibacterial activity, and the dosage is selected so that it does not reduce the osteoinductive properties of the entire product as a whole. Indications for use:

• After tooth extraction in order to reduce atrophy of the alveolar edge of the jaw.
• After tooth extraction for the purpose of osteoreparation, which allows earlier intraosseous implantation of supports for dentures.
• During resection of the apex of the tooth root for chronic periodontitis, cystogranulomas.
• After removal of jaw cysts (odontogenic and non-odontogenic) and removal of benign jaw tumors (fibroma, adenoma, etc.)
• During sequestrectomy for destructive osteomyelitis of the jaws.
• For radical flap operations for periodontal disease and for filling the periodontal pocket after its curettage for local periodontitis in order to restore the walls of the alveoli.
• When implanting denture supports (to achieve osseointegration).
• For alveoplasty with atrophy of the alveolar process.
• To raise the floor of the maxillary sinus in order to create conditions for intraosseous implantation.
• For contour plastic surgery (hernioplasty, in particular for dentofacial deformities).

The warranty shelf life is 3 years from the date of manufacture. Packaging: double bag made of polyethylene film, combined material or other materials approved for packaging medical products. The product is sterilized upon release by gamma rays at a dose of 1.5 MRAD. Contraindication:

• Polyallergy.
• Allergy to chlorine-containing substances.
• Allergy to collagen-containing drugs.

Instructions for use: After removing a tooth, cyst shell, sequestrum, benign tumor or other pathological tissue, blood clots are removed from the resulting bone defect with a stream of saline solution, a curettage spoon or a gauze swab. After treating the outer surface of the outer package - container with an antiseptic solution (furacilin, chlorhexidine, etc.), it is opened with sterile scissors and the small packaging bag containing a dental sponge is removed with sterile tweezers, the small package is opened with sterile scissors, the GSK-X-GA block is removed with tweezers -50 and inject it into the bone tissue defect. The number of blocks used is determined by the volume of the bone defect. Having ensured hemostasis, the edges of the soft tissue wound over the bone defect are brought together with sutures. After its removal, the tooth socket is filled with 1–2 GSK-Kh-GA-50 blocks to 1/4 of its depth. The edges above the hole are brought together with sutures or applied for 20–30 minutes. gauze swab. The patient is not recommended to eat for 4 hours. With contour osteoplasty and alveoplasty, the periosteum is peeled off from a small soft tissue incision. The resulting cavity (tunnel) is tightly filled with GSK-Kh-GA-50 blocks. The edges of the soft tissue wound are brought together with sutures. STORAGE CONDITIONS "Stimul Oss" in packaging of the enterprise is stored in protected from light, closed, clean warehouses without foreign odors. Manufacturer: JSC Luzhsky, Russia Price: 48.00 rub.

Analogs

Some patients believe that a hemostatic sponge is not able to stop bleeding and alleviate the patient’s plight. In reality, the effect of this medication is selective, and it is also important to consider the risk of side effects. In such clinical pictures, the attending physician introduces a replacement and suggests using an analogue of the specified pharmacological group. Here is a replacement worthy of modern pharmacology, which can also be purchased over the counter, but after consulting with your doctor first:

• Kaprofer;
• Alginatol;
• Natalsid;
• Eavisel;
• Polyhemostat;
• Tissucol Keith;
• Posterisan;
• Feracryl;
• Tachocomb;
• Styptic pencil;
• Tissucol.

Instructions:

Clinical and pharmacological group

20.015 (Hemostatic drug for local use)

Release form, composition and packaging

The sponge measures 2.5x3x0.5 cm, almost white, with a yellow coating on one side.

Excipients: albumin, arginine hydrochloride, collagen, sodium chloride, sodium citrate, riboflavin.

1 PC. — paper-polymer containers (1) — cardboard packs. 1 pc. — paper-polymer containers (3) — cardboard packs.

The sponge measures 4.8x4.8x0.5 cm, almost white in color, with a yellow coating on one side.

Excipients: albumin, arginine hydrochloride, sodium chloride, sodium citrate, collagen, riboflavin.

1 PC. — paper-polymer containers (2) — cardboard packs.

The sponge measures 9.5x4.8x0.5 cm, almost white, with a yellow coating on one side.

Excipients: albumin, arginine hydrochloride, collagen, sodium chloride, sodium citrate, riboflavin.

1 PC. — paper-polymer containers (1) — cardboard packs. 1 pc. — paper-polymer containers (5) — cardboard packs. 1 pc. — paper-polymer containers (10) — cardboard packs.

pharmachologic effect

Hemostatic drug for local use. Tachocomb consists of a collagen sponge coated on one side with components of fibrin glue (highly concentrated fibrinogen and thrombin), which promotes blood clotting. Upon contact with a bleeding surface or body fluids, the clotting factors contained in the coating are released. Thrombin converts fibrinogen into fibrin.

Pharmacokinetics

In the body, the components of Tachocomb undergo enzymatic breakdown within 3-6 weeks. A special production and sterilization process guarantees maximum safety of viruses and bacteria entering the sponge contents.

Dosage

Tachocomb should be applied to surgical wound surfaces under sterile conditions.

Before use, the wound surface must be cleaned as much as possible (including from blood, disinfectants).

The side covered with coagulation factors and marked in yellow should be applied to the wound surface and pressed for 3-5 minutes. When applying the sponge to sufficiently damp wound surfaces, no additional moisture is required. For dry wound surfaces, the sponge should be moistened with saline before application to achieve complete adhesion to the dry areas of the wound surface. The moistened Tachocomb sponge should be used immediately.

The size and number of Tachocomb sponges depend on the size of the wound surface. The edges of the wound should be covered with a sponge by 1-2 cm. If more than one sponge is required to close the wound, then when applied to the wound their edges should overlap each other.

Using sterile scissors, you can cut the sponges to the required size both before and after application to the wound surface. Unused sponge fragments must be destroyed.

Overdose

There are no reports of cases of overdose. Since the content of active components is very small, cases of overdose when using the drug are virtually impossible.

Drug interactions

No interaction with other drugs has been established.

Side effects

Possible increase in body temperature.

Storage conditions and periods

Should be stored out of the reach of children, at a temperature not exceeding 25°C. Shelf life: 3 years. Do not use after expiration date.

Indications

- in cases where bleeding, as well as biliary, fluid, lymphatic and air fistulas cannot be controlled by traditional methods or when the expected results of these methods are insufficient;

- to achieve hemostasis and “gluing” of tissues, especially during surgical interventions on parenchymal organs (liver, spleen, pancreas, kidneys, lungs, adrenal glands, thyroid gland);

- to stop bleeding during surgical interventions on ENT organs, gynecology, urology, vascular surgery, traumatology;

— for prevention of lymphatic, biliary and fluid fistulas;

- to create a seal during lung operations.

Contraindications

- hypersensitivity to the components of the Tachocomb sponge.

special instructions

The drug Tachocomb is available in sterile packages. Only undamaged packaging should be used. Repeated sterilization is not possible.

Conditions for dispensing from pharmacies

The drug is available with a prescription.

Hemostatic sponge price

The specified drug is easy to find on the open market, but it is also easy to order via the Internet on thematic websites from detailed catalogs. In the latter case, it turns out to be somewhat cheaper, and delivery is not delayed. Before making such a relevant purchase for yourself, it is important to find out not how much the hemostatic sponge costs, but whether it is suitable for the patient’s specific clinical picture or not. If there are no medical contraindications for use, you can use reliable information from the table below with metropolitan prices:

Contraindications

There are no indications for limiting the use of collagen plates in children, the elderly, pregnant women and nursing mothers .

Contraindications: - Increased individual sensitivity to the components of the drug; — Intolerance to nitrofuran drugs (furacilin, furagin); - Arterial bleeding; — Purulent wounds, pyoderma.

Sources:

Spoiler

https://medi.ru/instrukciya/gubka-gemostaticheskaya-kollagenovaya_3437/

https://sovets.net/12436-gemostaticheskaya-gubka.html

https://medams.ru/gybka_kollagenovaya_krovoostanavlivayushaya

https://DentConsult.ru/udalenie/gemostaticheskaya-gubka-v-stomatologi.html

https://dantist55.ru/hirurgiya/alvostaz-gubka.html

https://zubodont.ru/alvostaz-gubka/