Omaron - description of the drug, instructions for use, reviews

To treat neurological pathologies, specialized drugs are used that improve mental activity, memory, and increase concentration by normalizing blood circulation and metabolism in the brain. One of these remedies is Omaron. The drug simultaneously has vasodilating, antihypoxic and nootropic effects.

The medicine belongs to the clinical-pharmacological group of psychostimulants and neurotropic medications and the class of nootropics in combinations. Omaron is an inexpensive drug, available in pharmacies only with a doctor's prescription. The price depends on the number of tablets - 110-120 rubles (30 pieces), 160-170 rubles (60), 210-220 rubles (90).

A general description of Omaron, instructions for using the tablets, substitutes and reviews from people taking the tablets are in our article.

Pharmacological properties of the drug Omaron

Pharmacodynamics. A combined drug that has a pronounced antihypoxic, nootropic and vasodilating effect. Piracetam activates metabolic processes in the brain by enhancing energy and protein metabolism, increasing the utilization of glucose by cells and their resistance to hypoxia, improves the processes of interneuronal transmission in the central nervous system, and regional blood flow in the ischemic area. Cinnarizine is a selective blocker of slow calcium channels, prevents the entry of calcium ions into cells and reduces their content in the plasma membrane depot, reduces the tone of smooth muscles of arterioles, reduces their response to biogenic vasoconstrictors (epinephrine, norepinephrine, dopamine, angiotensin, vasopressin). It has a vasodilating effect (especially of cerebral vessels, enhancing the antihypoxic effect of piracetam), without significantly affecting blood pressure. It exhibits moderate antihistamine activity, reduces the excitability of the vestibular apparatus, and reduces the tone of the sympathetic nervous system. Increases the elasticity of red blood cell membranes, their ability to deform, and reduces blood viscosity. Pharmacokinetics. Piracetam: quickly and completely absorbed into the gastrointestinal tract. The maximum concentration of piracetam in the blood plasma is achieved after 2–6 hours. The maximum concentration in the cerebrospinal fluid is achieved after 2–8 hours. Bioavailability is 100%. Does not bind to blood plasma proteins. Penetrates into all organs and tissues, passes through the placental barrier. Selectively accumulates in the cerebral cortex, mainly in the frontal, parietal and occipital lobes, cerebellum and basal ganglia. Not metabolized. After 30 hours, more than 95% is excreted by the kidneys. Cinnarizine: the maximum concentration of cinnarizine in the blood plasma is determined after 1–4 hours. It is 91% bound to plasma proteins. Actively and completely metabolized. The half-life is 4 hours. 1/3 m of metabolites are excreted in the urine, 2/3 in feces.

general information

Omarone belongs to the class of psychostimulants and neurotropic drugs and the group of nootropics in combinations. The drug contains two active components: piracetam and cinnarizine, which complement each other and determine the pharmacological specificity of the drug’s action. Omaron comes in one form. Omaron is a tablet, each of which contains 400 mg of piracetam and 25 mg of cinnarizine.

Piracetam is historically the first and main drug of the nootropic group, used in the treatment of neurological, psychiatric diseases, and drug addictions. Piracetam in Omaron activates metabolic processes in the brain by accelerating protein and energy metabolism, helping to normalize interneuron transmission and blood circulation in the brain. Piracetam also increases the resistance of brain cells during hypoxia. The mechanism of action of piracetam on the human body has not yet been fully studied.

Cinnarizine is a drug claimed to improve blood circulation in the brain and as a peripheral vasodilator (vasodilator). This drug has a vasodilating effect, which helps normalize blood circulation, while the drug does not affect blood pressure. The action of the drug is mainly aimed at the cerebral vessels. Cinnarizine in Omaron helps improve the rheological characteristics of blood, reducing its viscosity and increasing the elasticity of membranes in red blood cells. The bioavailability of the drug Omaron is 100%.

Indications for use of the drug Omaron

Insufficiency of cerebral circulation (atherosclerosis of cerebral vessels, the recovery period of ischemic and hemorrhagic stroke, traumatic brain injury, encephalopathy of various origins, intoxication; other diseases of the central nervous system, accompanied by a decrease in intellectual and mnestic functions (impaired memory, attention, mood), psychoorganic syndrome with a predominance signs of asthenia and adynamia, asthenic syndrome; labyrinthopathy, Meniere's syndrome; mental retardation in children; prevention of migraine and kinetosis.

Reviews from patients, recommendations from doctors

The drug Omaron, reviews of which can be found on the Internet, is effective for impaired cognitive function, memory disorders, headaches, migraines, and seizures. Many patients note an improvement in memory and thought processes. However, it is worth considering that many disorders in the brain are a consequence of age-related changes in the body. Doctors do not recommend using Omaron, reviews of which indicate positive dynamics during treatment, for more than 3 months. Some patients note a resumption of symptoms with the abolition of Omaron. Today, Omaron is one of the most effective and harmless drugs for normalizing cerebral circulation and improving memory.

Special instructions for the use of the drug Omaron

Should be used with caution in persons with liver and/or kidney disease. For mild to moderate renal failure (especially with creatinine clearance ≤60 ml/min), the therapeutic dose should be reduced or the interval between doses should be increased. In persons with impaired liver function, it is necessary to monitor the level of liver enzymes. You should avoid drinking alcohol during treatment. The drug is prescribed with caution for increased intraocular pressure, as well as Parkinson's disease. During treatment, caution should be exercised when driving vehicles and operating machinery.

Application, contraindications, side effects, interactions with other drugs

The drug Omaron, the use of which is effective for various disorders of brain activity, is indicated in the following cases:

• Asthenic disorders;
• Mental retardation of unspecified etiology;
• Encephalopathy of various etiologies;
• Cerebral infarction and elimination of consequences;
• Intellectual-mnestic disorders;
• Intracranial injuries, intracranial hemorrhages and elimination of consequences;
• Cerebral atherosclerosis;
• Migraine;
• Dizziness, imbalance;
• Vestibular dysfunction;
• Meniere's disease.

Omarone is also used to eliminate the symptoms of kinetosis (seasickness), the leading role in the development of which is played by the receptors of the vestibular apparatus, which respond to changes in body position, transmitting signals about the speed of these changes to the brain. The causes of seasickness still remain unclear. It is also believed that one of the possible reasons for the appearance of symptoms is a conflict of signals received by the brain from the visual apparatus and from the receptors of the vestibular apparatus. To relieve symptoms of kinetosis and prevent motion sickness (sickness when moving), you should take one Omaron tablet 30 minutes before the intended trip.

Omarone, the use and dosage of which is prescribed by the attending physician, is a relatively safe drug. Side effects of the drug Omaron:

• Dyspepsia;
• Drowsiness, depressive disorders, excitability, irritability;
• Allergic reactions, dermatitis (rash, redness of the skin);
• Sleep disturbance;
• Slight fluctuations in blood pressure;
• Increase in body weight;
• Headaches, dizziness.

The main contraindications for the use of the drug Omaron are:

• Impaired kidney and liver function;
• Pregnancy and lactation;
• Allergic reactions to drugs of the group;
• Age up to 5 years.

Impaired renal and liver function is not an absolute contraindication to the use of the drug. Omarone is prescribed to patients with mild or moderate renal failure in lower therapeutic doses and at longer intervals. If liver function is impaired and Omaron is used, it is necessary to monitor the level of enzymes over time. Omarone may increase the manifestation of the symptomatic complex of Parkinson's disease.

The drug Omaron can have an activating effect on sedatives that depress the activity of the central nervous system, antihypertensive and nootropic drugs, and alcohol. Omarone improves the tolerability of tricyclic antidepressants.

When prescribing Omaron tablets, the use of other medications must be agreed with your doctor.

In case of an overdose of Omaron, pronounced side effects occur. To eliminate the consequences of an overdose, symptomatic treatment is used.

Omaron

Omarone (piracetam + cinnarizine) is a combined nootropic drug. It is used for circulatory disorders in cerebral vessels (in the presence of atherosclerotic plaques in their lumen, during the rehabilitation period after an ischemic or hemorrhagic cerebral hemorrhage, TBI), diseases of the central nervous system, the manifestations of which are depression of cognitive functions, organic defects with asthenic and adynamic manifestations, diseases Meniere, delayed intellectual development in childhood, in order to prevent motion sickness syndrome and migraines. Piracetam stimulates metabolic processes in brain cells by intensifying protein metabolism and energy metabolism, increasing the ability of cells to absorb glucose and tolerate a lack of oxygen. Piracetam also promotes more productive transmission of nerve impulses to the central nervous system and improves regional blood circulation in ischemic areas. Cinnarizine – selectively blocks L-type calcium channels (the so-called “slow calcium channels”), prevents the entry of calcium ions into cells and their accumulation in the plasmalemma, causes relaxation of the smooth muscle “cocoon” of small arteries, reduces their sensitivity to the effects of endogenous vasosuppressors. It exhibits vasodilating properties (mainly in relation to cerebral vessels, potentiating the antihypoxic effect of its “partner” - piracetam), without causing a significant decrease in blood pressure. Acts as a histamine antagonist, desensitizes the vestibular apparatus, and reduces sympathetic tone. Makes erythrocyte membranes more elastic and resistant to deformation, improves the rheological characteristics of blood. Piracetam is quickly and almost completely absorbed from the gastrointestinal tract.

Bioavailability (an indicator reflecting the ability of a drug to be absorbed in the body) approaches 100%. Accumulates in the cerebral cortex. It does not undergo metabolic transformations, unlike cinnarizine, which is metabolized in full. Piracetam is excreted mainly in the urine, cinnarizine in the feces. Omarone is contraindicated in persons with hypersensitivity to piracetam, cinnarizine or auxiliary components of the drug, severe liver and kidney damage, Parkinson's disease, pregnant and lactating women. In pediatrics, the drug is used starting from the age of 5. Single dose for children and adults – 1-2 tablets. Frequency of application: three times a day (adults), 1-2 times a day (children). The duration of the medication course is 30-90 days. Possible unwanted side effects: dyspepsia, headache, sleep disorders, allergic reactions (in rare cases). When using Omaron with drugs that suppress the activity of the central nervous system, alcohol, and antihypertensive drugs, the sedative effect may be potentiated. Vasodilators potentiate the effect of Omaron. In persons with liver and kidney diseases, the drug should be used with extreme caution. It is recommended to abstain from alcohol during treatment. With a long course of medication (2.5-3 months), the main functional indicators of the liver and kidneys should be monitored. During the medication course, it is recommended to refrain from activities that require increased attention and concentration (including driving a car and working with potentially dangerous mechanisms).

Price

You can buy Omaron only with a prescription from a doctor. The drug is stored at temperatures up to 25 degrees for three years from the date of manufacture. Approximate prices for the product in Moscow will be:

Reviews about "Omaron"

The effectiveness of the drug, its availability, and the rapid appearance of signs of positive dynamics have become the key to a large number of positive reviews. If the rules for taking the drug are observed and the treatment regimen is strictly followed, patients note a smoothing of the clinical picture characteristic of chronic vascular pathologies of the central nervous system. Favorable changes in the condition of the respondents were observed not only with a course of use of the medication, but also with a one-time dose.

In negative reviews of the drug, consumers refer to the abundance of contraindications, side effects, and decreased quality of life due to drowsiness. According to statistics, most of the problems listed can be avoided if therapy is carried out under the supervision of a doctor.

Overdose

With monotherapy, the probability of developing an overdose while using the drug is only a few tenths of a percent. To do this, it is necessary to significantly exceed the therapeutic volumes of the drug. In the case of an integrated approach to the treatment of diseases against the background of organic disorders, the risks are significantly higher. Under the influence of other medications, the chemical activity of Omaron may change, leading to unexpected consequences.

The clinical picture of an overdose is characterized by a decrease in blood pressure, nausea and vomiting, and impaired consciousness. In serious cases, bloody diarrhea and abdominal cramps are possible. Antidotes or hemodialysis are not used for such disorders. First aid consists of gastric lavage, taking enterosorbents, and carrying out symptomatic therapy.

Drug interactions

It is not recommended to combine the drug with alcohol and medications or drinks containing ethanol. Other restrictions and possible reactions in case of combination of Omaron with other drugs:

1. It is possible to enhance the sedative effect of drugs that depress the activity of the nervous system, nootropic and antihypertensive drugs.
2. Vasodilating drugs can enhance the effect of the drug.
3. Omaron improves the tolerability of antipsychotropic drugs, tricyclic and tetracyclic antidepressants, and enhances the effect of oral anticoagulants.
4. The combination of piracetam with thyroid hormones leads to an increase in the central effects of the latter, which causes tremors, irritability, anxiety, and sleep problems.

Directions for use and dosage

Instructions for use of Omaron are advisory in nature. The dose and treatment regimen are prescribed by the doctor after a medical history and examination of the patient. Tablets are taken orally before or after meals according to the dosage regimen.

For adults, Omaron is prescribed in the amount of two tablets up to three times a day. Patients over five years old: 1 tablet up to two times a day.

For adolescents, a course of treatment of more than three months is undesirable.

Repeated courses of treatment are possible up to three times a year.

Analogues of the drug

Analogues of Omaron for the active substance are Phezam, Combitropil, Piracezin, NooKam. Substitutes for therapeutic effect - Pantogam, Vinpocetine, Thiocetam, Glycine, Lucetam, Cavinton, Aminalon, etc.

Characteristics of analogues:

• Vinpocetine. The release form is tablets, the active component is the same name of the drug. The drug affects the central nervous system, increases blood circulation in the brain, provides a vasodilator, antiaggregation and antihypoxic effect. Use is prohibited in the acute period after a hemorrhagic stroke, with a severe form of arrhythmia, or coronary artery disease. Not prescribed to pregnant and lactating women, children under 18 years of age.
• Cavinton - contains vinpocetine, one tablet contains 5 mg. Another form of release is a concentrate for intravenous infusion. The medicine is used in neurological, ophthalmological and otorhinolaryngological practice. Contraindications: coronary heart disease, severe arrhythmia, pregnancy and lactation. The drug is well tolerated, common side effects are drowsiness, loss of strength, weakness, dyspepsia.
• Lutsetam. The active component of the drug is piracetam. Release forms: tablets, injections for intravenous/intramuscular administration. Main indications for use: mnestic-intellectual disorders, cortical type of myoclonus.
• Pantogam. The active ingredient in the drug is hopantenic acid. Release forms: syrup and tablets. The product belongs to the group of nootropics. Allowed for use from 3 years of age. The treatment regimen is selected individually, it all depends on the specific disease and the age of the patient.

For children

The instructions for the medication indicate that it can be used to treat children over 5 years of age. In practice, this instruction is often ignored when using the composition when working with children over the age of one year. This therapy is carried out for intrauterine brain damage, the child’s recovery after an infection, or serious traumatic brain injury.

Purposes of prescribing the drug to children over 5 years of age:

• elimination of sleep problems in the form of frequent awakenings, nightmares, difficulty falling asleep;
• improving intellectual endurance, strengthening physical health, combating increased fatigue;
• the fight against children's whims and other signs of emotional instability against the background of overwork and adolescence;
• relief of headache attacks due to increased intellectual activity, reducing their number;
• facilitating the process of adaptation to a new place, in an unusual environment;
• combating manifestations of juvenile hypotension or hypertension, eliminating sudden changes in blood pressure;
• helping the child’s brain to absorb large amounts of information, stimulating the intellect to facilitate understanding of the school curriculum;
• solving problems caused by delayed development of social skills, such as speech;
• prevention of complications due to functional, physiological or organic lesions of the central nervous system.

Pediatricians, neurologists, and psychotherapists are increasingly including Omaron and its analogues in complex therapy for autism and conditions similar in nature. The product is not able to get rid of the problem or at least influence its causes, but it can weaken the severity of the clinical picture and smooth out neurological symptoms.

Side effects

During treatment with Omaron, side effects may occur. Instructions for use indicate the following reactions:

• retardation of movements, irritability, headache, drowsiness, depression, ataxia, insomnia, epileptic seizures, tremor, imbalance, anxiety, decreased concentration, agitation, increased libido, hallucinations, dizziness;
• fluctuations in blood pressure;
• nausea, dyspepsia, vomiting, dry mouth, diarrhea, jaundice, abdominal pain;
• dermatitis, skin itching, rash;
• weight gain;
• allergic reactions, urticaria, angioedema;
• lupus-like syndrome, lichen planus.

An overdose of the drug is possible due to the anticholinergic activity of cinnarizine. Symptoms of overdose are vomiting, decreased blood pressure, impaired consciousness, and extrapyramidal symptoms. Taking piracetam in a dose of over 75 g leads to abdominal pain and bloody diarrhea. There is no specific antidote to Omaron. In case of overdose, it is necessary to lavage the stomach and give the victim a sorbent. Hemodialysis is 50-60% effective.

Composition and release forms of Omaron

The medication is available only in tablet format; there are no other forms of the drug. Its composition and description are shown in the table:

During pregnancy and lactation

Despite the severity of the positive properties that Omaron has, the use of the drug

prohibited at all stages of pregnancy. There are no official data on the effect of the drug on the condition of the fetus. The warnings of scientists and doctors are associated with the potential for changes in the psycho-emotional state of the expectant mother under the influence of the components. Excessive tension, mood swings and anxiety threaten complications during pregnancy and the development of problems in the fetus.

You will also have to stop taking the medication during lactation. The components and metabolites of the drug can pass into breast milk in significant quantities, having a direct effect on the child’s condition. If specialized therapy is necessary, the baby is transferred to artificial feeding.

Similar drugs:

• Bifren Capsule
• Cavinton forte Oral tablets
• Predizin Oral tablets
• Neurox Solution for intravenous and intramuscular administration
• Meldonium Capsule
• Meldonium Solution for injection
• Phezam Capsule
• Semax Nasal Drops
• Cavinton Oral tablets
• Ubidecarenon Substance-powder

** The Drug Directory is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; Before starting to use the drug Omaron, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace medical advice and cannot serve as a guarantee of the positive effect of the drug.

Are you interested in the drug Omaron? Do you want to know more detailed information or do you need a doctor's examination? Or do you need an inspection? You can make an appointment with a doctor - the Euro lab is always at your service! The best doctors will examine you, advise you, provide the necessary assistance and make a diagnosis. You can also call a doctor at home . Euro lab clinic is open for you around the clock.

** Attention! The information presented in this medication guide is intended for medical professionals and should not be used as a basis for self-medication. The description of the drug Omaron is provided for informational purposes and is not intended for prescribing treatment without the participation of a doctor. Patients need to consult a specialist!

If you are interested in any other drugs and medications, their descriptions and instructions for use, information about the composition and form of release, indications for use and side effects, methods of use, prices and reviews of drugs, or you have any other questions and suggestions - write to us, we will definitely try to help you.

Omaron's analogues

Omarone has both structural analogues and substitutes with similar effects. Structural analogues include Phezam and Combitropil.

Phezam is an analogue based on piracetam and cinnarizine, available in the form of hard gelatin capsules. Contains milk sugar. Otherwise, Fezam is completely identical to Omaron; both drugs have a similar mechanism of action, scope of application and can cause the same side reactions. Fezam is produced in Bulgaria.

Combitropil is a similar product produced domestically. The pharmacological effect of Combitropil is based on the action of two active substances - cinnarizine and piracetam. The medicine is sold in the form of capsules placed in cardboard packaging. One package may contain 20, 30 or 60 capsules.

The closest analogue in terms of effect on the body is Aminalon. A nootropic drug whose active ingredient is GABA (aminalone). The medication does not contain milk sugar, which makes it possible for people with lactose intolerance to take Aminalon. Aminalon can be found commercially in the form of film-coated tablets. One tablet may contain 250 or 500 mg of active substance, depending on the manufacturer. Used for atherosclerosis, senile dementia and encephalopathy.

See also:

Fevarin - instructions for use, reviews from patients who took the drug and psychiatrists

Drug compatibility and special instructions

If you combine Omaron and sedatives and other drugs that have a depressing effect on the nervous system, their effectiveness increases. A similar result is observed when combined with ethanol, medications with nootropic and antihypertensive properties. Vasodilating drugs enhance the effect of Omaron.

Omaron improves the tolerability of antidepressants (tricyclic) and antipsychotic drugs. When used in parallel with oral anticoagulants, the effect of the latter increases.

Special instructions:

1. During prolonged use, the patient is under medical supervision.
2. When the medicine is prescribed for a period of one and a half months, it is necessary to monitor the functions of the kidneys and liver.
3. During therapy, patients with hypertension may experience a significant decrease in blood pressure.
4. During the therapeutic course, alcohol is prohibited.
5. There is a high probability of a false negative/false positive result of a doping test in athletes.
6. Possible distortion of allergy skin tests. Omaron is discontinued 4 days before the study.
7. Mexidol and Omaron can be taken together, no drug interactions have been found.

During treatment, extreme caution must be used when driving. It is advisable to exclude engaging in potentially hazardous activities that require a high speed of psychomotor reactions and increased concentration.

Analogs

The pharmaceutical industry offers dozens of drug analogues. The long list includes: “Glycine”, “Vinpocetine”, “Nootropil”, “Pantogam” and many other products.

You can learn more about the drug Glycine here.

Such a variety of medications allows you to choose the best option, the appropriate dosage form.

Some analogues of the drug are sold in pharmacies without a prescription, but this does not mean that they can be used without prior approval from a doctor. Despite the similarity in therapeutic effect, the products contain different active ingredients. This point affects the list of contraindications, side effects, and peculiarities of drug use.