Gioksizon ointment is produced by three leading Russian companies, NIZHFARM, Murom Instrument-Making Plant, and Pharmaceutical Factory in St. Petersburg. The product belongs to glucocorticosteroids for local use. Additionally, an antibiotic from the tetracycline group was introduced into the composition.
The drug has anti-inflammatory, immunosuppressive, antipruritic, and local vasoconstrictor effects. Effective against secondary bacterial infections caused by mycoplasmas, treponemas, rickettsia, chlamydia and spirochetes (Treponema spp, Mycoplasma spp, Rickettsia spp), which often accompany skin lesions.
Compound
Hyoxysone is a two-component pharmacological product that has the ability to manifest inflammatory processes on the skin and eliminate the consequences of bacteriological infection.
The basis of the composition are the active substances:
- oxytetracycline;
- hydrocortisone.
For better absorption of active chemical compounds and a convenient method of treating focal zones in production, the following are also used:
- medical Vaseline;
- Vaseline oil;
- nipagin.
The dosage form of Gioxyzon is a yellowish ointment with a thick consistency. The product is packaged in aluminum tubes of 10 g.
pharmachologic effect
The therapeutic effect is achieved thanks to the unique properties of the active ingredients:
- Oxytetracycline – the substance is an antibiotic; if the treatment regimen is followed, it inhibits the ability of microorganisms to reproduce. Shows activity against gram-negative and gram-positive bacteria (Treponema spp, Mycoplasma spp, Rickettsia spp, etc.).
- Hydrocortisone – the component is characterized by a wide spectrum of effects on the human body. There is a high effectiveness of treatment due to anti-inflammatory, anti-allergic, anti-exudative and antipruritic effects.
Price
You can buy dermatological ointment at almost any pharmacy or by leaving a request on the online store website.
The second option is convenient in that it is possible to deliver medications to your home.
Gioksizon differs from other drugs with similar pharmacological properties in its affordable price.
The cost of one tube is 60-85 rubles .
The medicine is dispensed with a prescription sheet . If you order a product online, you can purchase it without presenting it.
Analogs, price
The average cost of a ten-gram tube is fifty rubles, and a twenty-five-gram tube is about 85 rubles. The combination of active ingredients used in Gioxyzone is by no means unique. There are a large number of similar drugs. Let's look at its analogues for children:
- Oxycort - has a similar composition, produced in Poland. Costs about 150 rubles;
- Cortomycetin is a domestic product containing hydrocortisone and chloramphenicol. Cost - 30 rubles;
- Pimafucort is an Italian analogue that contains hydrocortisone in combination with natamycin and neomycin. Cost - 600 rubles;
- Fucidin - produced in Denmark. Fusidic acid is used as an antibiotic in its composition. Cost - 400 rubles;
- Belogent is a Croatian medicine. The active ingredients are betamethasone in combination with gentamicin. Cost - 350 rubles.
As can be seen from the above data, we can conclude that Gioksizon is an excellent example of an adequate price-quality ratio of a drug.
Indications for use
Before you start using the medicine, it is recommended that you read the instructions, carefully studying what the ointment helps with and how to use it correctly.
The hormonal drug provides effective treatment for the following skin problems:
- allergic rashes;
- folliculitis;
- furunculosis;
- erosive manifestations that arose against the background of wound infection by bacteria;
- dermatitis of any etiology;
- ulcers of varicose origin;
- seborrhea;
- eczema, etc.
The list of what the product is used for is not limited to the listed pathologies.
The ointment effectively eliminates the consequences of erysipelas and urticaria.
The medicine is used to treat burns, diaper rash, bedsores, and frostbite.
If the site of an insect bite becomes severely inflamed, Gioxyzon will stop the progressive pathological process and accelerate tissue healing.
The dermatological product is no less popular among cosmetologists . Due to its anti-inflammatory and antibacterial effect, the ointment is used in procedures to cleanse the skin of acne and other blemishes.
Restrictions on use
The manufacturer warns in the annotation about the presence of contraindications to the use of the drug.
You should avoid using Hyoxyzone if you have the following pathologies:
- oncology and predisposition to neoplasms;
- cutaneous tuberculosis;
- mycosis;
- diseases caused by viruses.
The active substances of the drug exhibit a high therapeutic result if the skin lesion is not caused by viruses. Therefore, it is not advisable to use Hyoxysone for smallpox, herpes, chickenpox, rubella and other viral infections.
In pediatrics, ointment is prescribed more often from the age of 6 . In rare cases, specialists make an exception provided that the patient is treated in a hospital under the supervision of medical staff.
special instructions
When treating with Hyoxysone ointment, you need to follow some rules:
- Preparations containing corticosteroids are not used to prevent skin diseases. When symptoms disappear, stop taking them.
- To reduce the risk of side effects and quickly reduce the therapeutic effect, the drug is used in short courses with breaks. This is a more preferable option than long-term continuous use.
- Infants, especially premature babies, have relatively thin skin. The ratio of its surface area to body weight is increased, which determines the careful use of GCS. This also applies to elderly patients.
- Vaccination with simultaneous treatment with steroid drugs is not recommended due to the immunosuppressive effect.
- Application to large areas and under an occlusive dressing leads to increased absorption of GCS into the blood. These techniques are not recommended for children under 8 years of age.
- For extensive skin lesions, exudative inflammation, and intolerance to components, treatment with aerosols is advisable.
Instructions for use
The medicine is intended for external use.
It is recommended to treat the affected area of skin 1-3 times a day. A single dose depends on the extent of the focal zone (on average, 0.5-1 g is required for treatment).
If necessary, cover the wound with a gauze pad/bandage (necessarily sterile) after applying the cream.
Before the initial use of a dermatological drug, it is recommended to test the sensitivity of the skin microflora to the active ingredients.
Gyoksizon ointment - contraindications
Before starting treatment, you should familiarize yourself with the following list of contraindications that Hyoxysone ointment has for external use:
- hypersensitivity to the components of the product;
- skin tumors;
- mycoses;
- viral skin lesions;
- lupus;
- precancerous and cancerous skin conditions;
- rosacea;
- fragility of skin blood vessels;
- atrophy of the skin and subcutaneous tissue;
- perioral dermatitis;
- period after preventive vaccinations;
- pregnancy;
- lactation period (in case of extensive lesions).
Side effects
When studying the spectrum of effects of Hyoxyzone on the human body, rare cases of side effects were identified.
Possible effects include:
- the appearance of spider veins when using the product on the skin of the face;
- irritation;
- itching;
- rash.
Symptoms are short-lived and disappear 1-3 hours after the procedure.
Longer and worsening symptoms indicate a serious complication, which is often associated with an allergic reaction. In this case, you should seek qualified help.
Gyoksizon ointment - side effects
The use of hyoxyzone ointment is associated with the risk of developing the following local and systemic adverse reactions:
- burning, itching of the skin;
- rashes of various types;
- excess hair growth;
- skin depigmentation;
- photosensitivity;
- formation of striae;
- tissue maceration;
- atrophy of subcutaneous tissue;
- steroid addiction;
- dilation of small blood vessels in the skin;
- angioedema;
- adrenocortical suppression;
- hyperglycemia;
- glucosuria;
- Cushing's syndrome;
- intracranial hypertension;
- increased intraocular pressure.
Hyoxysone in cosmetology
In addition to dermatology, the drug is widely used in cosmetology.
It is used in procedures aimed at eliminating the following flaws:
- acne;
- acne (positive results are observed even in severe forms);
- acne.
Effective experience with drug treatment is not a reason to recommend the use of the drug to third parties without a doctor’s prescription.
The medicine contains hormones , which if used inappropriately can result in a number of serious complications. In addition to allergies, self-medication can disrupt hormonal levels with ensuing consequences.
Precautionary measures
The use of hormonal agents to eliminate skin problems requires the following precautions:
- If, after applying the ointment, side effects appear (irritation, rash) with increasing symptoms, use should be discontinued. To eliminate alarming symptoms, you need to take an antihistamine.
- If a week's treatment of the focal area does not improve the condition of the skin, it is recommended to consult your doctor to select a substitute or conduct additional diagnostics. Hydrocortisone may mask symptoms of a more serious infection.
- The maximum course of treatment is 2 weeks. Ignoring the warning leads to the development of mycotic superinfection and resistance to various types of bacteria.
- When applying the ointment to wounds or other lesions, it is important to avoid contact of the composition with mucous membranes and open areas of the skin.
- When using the medicine on the face, do not touch the area around the eyes. The active ingredients of the ointment can provoke the development of cataracts and glaucoma.
- Patients diagnosed with psoriasis should use dermatological ointment with caution due to the corticosteroid content.
- When treating wounds on the skin of the face, in the groin area, and armpits, there is a danger of side effects. This is explained by increased absorption of the active substances of the drug in the listed areas of the body.
- Long-term use of Gioksizon is fraught with such consequences as: Itsenko-Cushing syndrome, glucosuria, hyperglycemia, etc.
Hyoxysone during pregnancy
The obstetric debate surrounding the use of corticosteroids during pregnancy continues. Steroid hormones are produced by the adrenal cortex, ovaries, and placenta. The functions of GCS are adaptation of the body in stressful situations, influence on the metabolism of proteins, fats, carbohydrates and nucleic acids.
Increased levels of corticosteroids inhibit cell division and development. The most sensitive to this are fast-growing cells of the immune system and the fetus.
Glucocorticoids act on the liver to increase glycogen stores. The synthesis of nucleic acids shifts in its direction, as hormones suppress the production of biopolymers by the body. GCS affect renal function by inhibiting the secretion of vasopressin. They have an effect on the mental state, since excess or lack of cortisol causes emotional disorders.
In the 50-60s of the last century, the use of glucocorticosteroids became widespread. Observations revealed no connection between treatment with steroid hormones and fetal development disorders. Cases of deformities, miscarriages and other pathologies of pregnancy did not exceed the number of anomalies in the population not taking GCS.
Currently, the use of Geoxyzon therapy during pregnancy is possible if the risk of maternal disease is more serious than the likely effect of the drug on the fetus.
Reviews
Natalya, 35 years old:
Hyoxysone is always available in the home medicine cabinet; I take the ointment with me on picnics when the whole family goes out into the countryside for active recreation. Any inflammation on the skin, burns and allergic manifestations disappear after several treatments. Before using the medicine for the first time, I was confused by the list of side effects. However, during the use of the ointment, there were no negative reactions of the body to the active substances.
Egor Alexandrovich, 54 years old:
The children gave me a summer cottage plot, so I spent the entire last season in the garden. We had to fight weeds in different ways. After one such attack, an itchy rash appeared on the skin of the arms up to the elbows. I always dealt with minor health problems myself. The use of several types of medicinal creams did not give the expected effect. I had to see a doctor.
The drug Gioxyzon Akrikhin recommended by him showed effectiveness after 2 treatments of the affected skin areas.
Vera Alekseevna, 49 years old:
I am an allergy sufferer with over 15 years of experience. I had to use whatever I could to eliminate the characteristic symptoms. For the past 3 years, when signs of allergies appear on the skin, I have been treating with Hyoxysone ointment. But it helps me with burns and with inflammatory processes that begin after cuts or other lesions of the skin.
After purchasing the drug, it was difficult to believe the impressive list of indications from the annotation. I thought it was just another marketing ploy. But in the case of this ointment, there is no doubt about its effectiveness, which is proven by our own experience.
Release form and composition
The drug Gioksizon Akrikhin ointment is available in the form of a white, odorless cream in aluminum tubes, in packages of 10 or 25 g. One gram of the drug contains:
- hydrocortisone – 10 mg;
- oxytetracycline – 30 mg.
Excipients:
- Vaseline oil;
- liquid paraffin;
- nipagin.
Analogs
If it is not possible to use Gioksizon for some reason, you should contact a specialist to select an analogue.
You can replace the ointment with medications that have identical pharmacological properties.
Among the most effective:
- Oxycort;
- Bactroban;
- Dimexide;
- Flucinar N;
- Dioxidine;
- Clarithromycin.
The selection of substitutes is carried out by the attending physician, taking into account the following factors:
- condition of the skin in the focal area;
- concomitant health problems of the patient;
- hormonal ointment or not.
The correct search for an analogue is based on the principle of matching the pharmacological properties of a potential variant with the original.
