Mydocalm: instructions for use, what it helps with - Price, reviews and analogues + Photo

Compound

International nonproprietary name of the drug (INN) Tolperisone.
One Mydocalm tablet contains 50 or 150 mg of tolperisone hydrochloride as an active substance, as well as auxiliary components:

• citric acid monohydrate (Acidum citricum monohydrate);
• colloidal silicon dioxide (Silicii dioxydum colloidale);
• stearic acid (Acidum stearicum);
• talc (Talcum);
• microcrystalline cellulose (Cellulosum microcrystallicum);
• corn starch (Amylum maidis);
• lactose monohydrate.

The film coating with which the tablets are coated contains:

• colloidal silicon dioxide (Silicii dioxydum colloidale);
• titanium dioxide (Titanium dioxide);
• lactose monohydrate;
• macrogol 6000 (Macrogol 6000);
• hypromellose (Hypromellose).

Mydocalm and alcohol

During the studies, it was found that the drug does not affect the effects of ethanol-containing substances on the central nervous system. Medicines containing ethanol are approved for use during treatment. Drinking alcohol during treatment with Mydocalm is not prohibited, although this combination may have a sedative effect if alcohol-containing drinks are abused.

Pharmacodynamics and pharmacokinetics

Mydocalm prevents the destruction of cell membranes and provides a pronounced membrane-stabilizing effect. lipid peroxidation processes and modulation of the activity of membrane-bound enzymes .

In addition, the drug acts as a local anesthetic, and also inhibits the conduction of nerve impulses in primary afferent (from the Latin “afferens” - bringing) nerve fibers and motor neurons - nerve cells responsible for transmitting information to effectors (usually muscles) from the central nervous system.

The latter leads to blocking of polysynaptic and monosynaptic reflexes of the spinal cord .

It is considered probable that Mydocalm has the ability to secondarily inhibit the processes of mediator release. This is ensured by inhibiting the flow of calcium ions (Ca2+) to places of functional contact between neurons , in which information is transmitted from one cell to another (or, in other words, to synapses).

In the brain stem, Mydocalm eliminates the facilitation of the spread of excitation along the reticulospinal tract (reticulospinal tract).

Promotes increased peripheral blood flow (regardless of the influence of the central nervous system), reduces pathologically increased muscle tone, eliminates muscle rigidity, reduces the severity of pain in the muscles, eliminates or reduces the severity of disorders of voluntary active movements.

This effect is ensured by the ability of tolperisone to have a mild antispasmodic and adrenergic blocking effect.

Thanks to the activity of tolperisone , Mydocalm also reduces the toxicity of the indole alkaloid strychnine , helps suppress the increase in reflex excitability caused by it and has vasodilating properties.

Some evidence suggests that the drug has a selective inhibitory effect on the caudal (from the Latin “cauda” - tail, caudal) part of the spinal cord formation going to the thalamus in the rostral direction (that is, to the cortex ) . As a result, the severity of spastic phenomena decreases.

tolperisone, which is part of Mydocalm, also causes a central H-anticholinergic effect.

The action of N-cholinergic drugs is based on the fact that, when they enter the body, they act on nicotinic receptors, localized mainly in postsynaptic membranes located in skeletal muscle synapses, ganglia of the autonomic nervous system the adrenal medulla , as well as in tissues sinocarotid zone .

By interacting with receptors, N-anticholinergics and, in particular, tolperisone, block their ability to perceive acetylcholine , as a result of which the nerve impulse is not transmitted through the blocked synapse. Thus, the neurotransmitter is released, but the blocked receptors of the postsynaptic membrane are no longer able to respond to the stimulus.

Tolperisone does not have a pronounced effect on the peripheral parts of the nervous system.

After taking the Mydocalm tablet, tolperisone is well absorbed from the gastrointestinal tract. The maximum concentration of the substance is observed after approximately half an hour to an hour. Its biological activity is about 20%.

Tolperisone undergoes intensive biotransformation in the tissues of the liver and kidneys. The substance is excreted from the body by the kidneys in the form of metabolic (more than 99%), the pharmacological activity of which is unknown.

Therapy for osteochondrosis

Mydocalm has a pronounced muscle relaxant effect and is distinguished by its selectivity of action. It reduces the excitability of muscle fibers, while simultaneously reducing the influence on nerve impulses, due to which the muscles gain strength when moving.

In addition to good tolerability, there are advantages such as no impact on the patient’s performance. The medication fits well into the classical treatment regimens for cervical osteochondrosis, as well as damage to its other parts.

Osteochondrosis involves the use of non-steroidal anti-inflammatory drugs, which may lead to adverse side effects. However, the combination with Mydocalm allows you to reduce their dosage. The effectiveness of treatment does not suffer at all. Today the drug is recognized as one of the safest and most effective muscle relaxants. It has been used in clinical practice for 50 years.

Indications for the use of Mydocalm, what it treats and what the drug helps with

Indications for the use of Mydocalm are:

• pathologically increased muscle tone and spasms of skeletal (striated) muscle tissue, which are a consequence of organic lesions of the central nervous system, including multiple sclerosis , encephalomyelitis , stroke , etc.;
• myogenic contractures, increased muscle tone and spasticity caused by diseases of the musculoskeletal system (for example, lumbago with sciatica , spondylosis , arthrosis affecting large joints , cervical syndrome , etc.);
• non-inflammatory diseases of the brain accompanied by disorders of muscle tone (for example, cerebral palsy );
• cholelithiasis;
• severe pain syndrome, observed against the background of the development of hemorrhoids;
• menstrual pain syndrome;
• the threat of spontaneous abortion due to increased tone of the uterine muscle structures;
• renal colic.

The use of the drug Mydocalm is indicated:

• during the period of rehabilitation therapy after orthopedic, surgical or traumatological operations (this is due to the ability of tolperisone to have a beneficial effect on the degree of stretching of muscle fibers);
• as part of complex therapy for obliterating vascular lesions (according to the annotation, the drug is effective for diabetic angiopathy , Raynaud's syndrome , thromboangiitis obliterans , etc.);
• for the symptomatic treatment of muscle spasm in adult patients who have had a stroke ;
• for pathologies caused by disorders of vascular innervation (severe gait disturbances or pathological cyanosis of the extremities).

Why are muscle relaxants prescribed for osteochondrosis?

Like other centrally acting muscle relaxants, Mydocalm can be prescribed for osteochondrosis .

The pain syndrome that develops with osteochondrosis provokes a compensatory spasm of the deep layers of the back muscles. And this, in turn, causes myofixation of the spinal column and limitation of the mobility of the spinal motion segments.

The consequence of such a muscular-tonic imbalance is a worsening of the course of the disease and a decrease in the therapeutic effectiveness of all measures taken.

Muscle relaxants for osteochondrosis are prescribed to eliminate this imbalance. Drugs from this pharmacotherapeutic group:

• have a sedative effect;
• relieve pain symptoms;
• suppress spinal reflexes;
• relieve muscle tension.

Thanks to these qualities, muscle relaxants increase the effectiveness of other therapeutic interventions: massage, physical therapy, traction therapy, etc. They also have the ability to potentiate the effect of blockades, other painkillers and physiotherapeutic procedures.

At the same time, muscle relaxants have a number of contraindications for use and can provoke undesirable side effects (in particular, with long-term treatment in patients, the function of the hepatobiliary system and body weight increases).

However, unlike chondroprotector , they actually improve the condition of patients suffering from osteochondrosis (which is achieved by removing pathological myofixation) and increase the effectiveness of conservative therapy.

To treat osteochondrosis, it is recommended to take muscle relaxants in very short courses. And yet, keeping in mind the abundance of side effects, medical practitioners very carefully include these drugs in the treatment regimens of their patients.

Impact on the body

The active substance in the structure of the muscle relaxant helps to stabilize the cell wall, preventing it from being destroyed. This effect is associated with the increased activity of certain enzymes and their selectivity in terms of changing metabolic processes. Mydocalm prevents the release of mediators from granules.

The structure of the drug is somewhat reminiscent of Lidocaine. The effect it has is local, analgesic. The release of mediators is inhibited, and then the speed of passage of the nerve impulse at the site of the lesion decreases, including in the neurons responsible for the innervation of muscle tissue. There is no impulse transmission along the spinal cord. Due to this, the stimulating effect of the central nervous system on the muscles is reduced. Conducting excitation in the reticular formation of the brain becomes more complicated.

Mydocalm has an adrenergic blocking effect and has an antispasmodic effect. Muscle tone decreases and pain is eliminated. At the same time, the number of active and passive movements is reduced. The lumen of the veins and arteries expands, which normalizes blood flow.

It was possible to determine the N-cholinergic effect of Mydocalm. This means that nicotinic receptors in the structure of the adrenal glands are blocked, as are the nerve branches in the muscle tissue. The acetylcholine supplied in this case does not affect the unresponsive receptors. The medication can be used as an antidote to strychnine when there are no other drugs of choice.

Contraindications

Contraindications to the use of Mydocalm tablets:

• age up to one year;
• persistent pathological weakness and rapid fatigue of skeletal muscle tissue ( myasthenia gravis );
• increased individual sensitivity to any of the components of the drug.

Before taking Mydocalm tablets for osteochondrosis , you should also take into account that all muscle relaxants are contraindicated in patients:

• currently or with a history of increased seizure activity;
• those suffering from Parkinson's disease ;
• suffering from chronic renal and/or liver failure ;
• those suffering from epileptic seizures ;
• having a history of drug addiction;
• with a history of acute psychosis .

Side effects of Mydocalm

The safety profile of tablets containing tolperisone is based on data from more than 12 thousand patients.

Statistics show that most often after taking tolperisone drugs, adverse reactions occurred such as systemic disorders, disorders of the skin and subcutaneous tissue, as well as nervous disorders and digestive disorders.

Post-marketing observations have shown that in 50-60% of cases, side effects associated with taking tolperisone drugs are reactions of increased individual sensitivity.

Most of these reactions do not threaten the patient’s health, do not require specific treatment and go away on their own.

Reactions of increased individual sensitivity, which are life-threatening, have been recorded in isolated cases.

In accordance with the MedDRA Medical Dictionary of Regulatory Activities, all side effects that occur during treatment with a particular drug are classified into frequent, infrequent, rare and very rare.

Infrequent (occur no more than once in a thousand cases) side effects that occur after taking Mydocalm include:

• eating and metabolic disorders, which are expressed in the form of anorexia ;
• insomnia and sleep disorders;
• headache , dizziness , increased drowsiness ;
• arterial hypotension;
• feeling of discomfort in the abdomen, diarrhea , increased dryness of the mucous membrane in the mouth, dyspeptic symptoms, nausea;
• muscle weakness, pain in the limbs, muscle pain;
• asthenia , feeling of general discomfort, increased fatigue.

Rare adverse reactions occurring more often than once in a thousand cases, but less than once in ten thousand cases:

• anaphylactic reaction;
• decreased activity, depressive states;
• disturbances of attention, tremor , increased convulsive activity, hypoesthesia (decreased sensitivity to the effects of stimuli), paresthesia , increased drowsiness;
• tinnitus , vertigo ;
• angina pectoris , tachycardia , rapid heartbeat, decreased blood pressure;
• hyperemia of the skin;
• difficulty breathing, nosebleeds, rapid breathing;
• pain in the epigastric region, constipation , flatulence , vomiting;
• liver dysfunction ;
• allergic dermatitis , increased sweating, itching, urticaria , skin rashes;
• feeling of discomfort in the limbs;
• enuresis , proteinuria ;
• feeling of intoxication, feeling of heat, irritability, increased thirst ;
• increased bilirubin levels in the blood, changes in the activity of liver enzymes, decreased platelet , leukocytosis .

Extremely rarely (no more often than in one in ten thousand cases) the following may occur:

• anemia , enlarged lymph nodes ( lymphadenopathy );
• anaphylaxis (anaphylactic shock);
• polydipsia;
• confusion;
• bradycardia;
• osteopenia;
• feeling of discomfort in the chest;
• increase in creatinine in the blood.

special instructions

The drug consists of natural substances, so taking it with impaired liver and kidney function is quite acceptable. It is often used in complex therapy of many diseases. It is noteworthy that Mydocalm is sometimes prescribed to pregnant women to reduce the tone of the uterus.

Young children are only allowed if they are over five years of age. If you study the forums where patients leave their reviews, we can conclude that Mydocalm must be taken comprehensively, since its use separately can provoke malaise.

The advantages of the medicine are its natural composition, a wide range of applications, a small number of contraindications and mild side effects that appear only in exceptional cases. Mydocalm is available without a prescription.

Mydocalm tablets, instructions for use (Method and dosage regimen)

The medicine is intended for oral administration. It is optimal to take it immediately after a meal, without chewing and with a small amount of liquid.

Adults are recommended to start treatment with the drug with a dose of 100-150 mg per day, divided into 2 or 3 doses. Further treatment involves a gradual increase in a single dose to 150 mg. The frequency of doses remains unchanged (2-3 per day).

Typically, the dosage is selected depending on muscle tone , pain , the presence of contraindications in the patient and concomitant chronic diseases.

Based on this data, the doctor also determines how many days to take the pills. The duration of the therapeutic course usually does not exceed ten days.

According to the instructions for use of Mydocalm, children under fourteen years of age are allowed to be prescribed tablets containing 50 mg of tolperisone.

Children aged from one to six years are given the drug Mydocalm in a dose equal to 5 mg of tolperisone per kilogram of the child’s body weight per day. The indicated dose is divided into 3 doses during the day. In cases where the child is not able to swallow a whole tablet, it is first crushed.

For children from seven to fourteen years of age, the instructions for use of Mydocalm recommend prescribing the drug in a daily dose equal to 2 to 4 mg of tolperisone per kilogram of the child’s body weight. The multiplicity of techniques is 3.

After oral administration, the drug begins to act after approximately forty minutes. The duration of action varies from 4 to 6 hours (it depends on how well the renal blood filtration system is functioning).

Treatment of certain diseases is supplemented with a complex of physiotherapeutic measures, gymnastics, massage courses, rubbing ointments, etc.

Reviews from patients and consumers

• Inna. After the first injection I felt very bad. It all started abruptly - dizziness, rapid heartbeat, cold, cold sweat. It got better a little later. I started reading everything about this drug. It must be administered very slowly, over 3-4 minutes. And the doctors from the ambulance administered it to me intravenously and very quickly, like regular medicine. This is mainly the effect of lidocaine. True, I then completed the course of intramuscular injections. So do not forget to read all about the side effects and dosage of the drugs before administering any drug. I think that many will agree with me.
• Zhanna. 3 years ago, doctors scared me with a terrible diagnosis of “arthrosis of the right forearm.” My hand hurt terribly and suffered from severe cramps. When the disease gets worse, I save myself with injections. A systemic course of Mydocalm relieves pain well, gives an anti-inflammatory effect, and “softens” the muscles. There are no adverse reactions, only positive results.
• Ira. I was prescribed Mydocalm after I suffered for a long time with a swollen and jammed neck. For a long time I could not turn my head; my neck muscles were very inflamed. This drug was prescribed to relax the neck muscles. I started taking it on the day of the prescription, but after a few doses I felt worse and there were side effects: the neck pain almost went away, but there was very strong weakness, shortness of breath, a heartbeat that was heavy and felt slow. In general, Mydocalm apparently didn’t suit me. It relaxed not only the neck, but also the heart muscle. I don't think I'll ever agree to accept it.

Overdose

There are no data on Mydocalm overdose. The drug is characterized as non-toxic and having a wide range of therapeutic effects. In the literature, there are descriptions of oral administration of a dose of tolperisone equal to 600 mg in pediatric patients. And without any serious toxic manifestations.

Oral intake by children of a dose equal to 300-600 mg, in some cases, may be accompanied by an increase in irritability.

The drug does not have a specific antidote. If the dose recommended by the instructions is exceeded and any undesirable symptoms appear against this background, the patient is recommended to undergo gastric lavage and then symptomatic and supportive therapy.

During pregnancy

Taking Mydocalm in the first trimester of pregnancy is not recommended, due to the lack of clinically proven evidence of the safety of the drug for the normal development of the embryo. Starting from the second trimester, pills can be prescribed by a doctor if the expected therapeutic effect of taking them is higher than the potential danger to the fetus.

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Interaction

There are no data on interactions with other drugs that would limit the use of Mydocalm.

Despite the fact that tolperisone has the ability to act on the central nervous system, it does not provoke a sedative effect. For this reason, it can be combined with sedatives, sleeping pills and drugs containing alcohol.

Tolperisone has no effect on the effect of alcohol on the central nervous system. The activity of the substance is enhanced by:

• preparations for general anesthesia;
• peripherally acting muscle relaxants;
• psychotropic drugs;
• clonidine (a substance that has a hypotensive effect).

Movalis, Mydocalm and Milgamma (drug compatibility)

Milgamma , Movalis and Mydocalm are well-combined drugs. Therefore, they are often prescribed as part of complex therapy for patients with pathologies of the musculoskeletal system.

Patients with this type of disease in the vast majority of cases suffer from severe joint pain. The use of Movalis and Mydocalm together can reduce the severity of pain, relieve spasms and muscle hypertonicity. In addition, Movalis is characterized by a neutral effect in relation to cartilage tissue.

The drug Milgamma belongs to the pharmacological group B vitamins and is used as a general tonic. It has a pronounced metabolic, analgesic and neuroprotective effect.

vitamins belonging to group B have a beneficial effect on inflammatory and degenerative diseases that affect the nervous system and musculoskeletal system.

The regimen for taking Movalis-Milgamma-Mydocalm is determined by the attending physician.

Use in injections

Mydocalm is applicable in the form of injections if there are problems with the musculoskeletal system, including osteochondrosis. It is used in this form to reduce pain and relax the paravertebral muscles. These also include pathologies such as radiculitis, in which a nerve is pinched, and diseases affecting the spinal cord.

Other indications include:

• Little's disease;
• cerebral palsy;
• neurological diseases in the active stage;
• muscle hypertonicity;
• inflammatory pathologies of joints.

There are also indications for the hematopoietic system. These are injuries and ischemia in the brain and spinal cord. The drug is also prescribed if the following are diagnosed:

• closing the lumen of blood vessels with blood clots;
• obliterating endarteritis;
• dermatomyositis;
• diseases of a systemic nature.

Other indications: the first days after orthopedic surgery, problems with microcirculation due to metabolic disorders. In urology, indications include various types of prostatitis, as well as inflammation of the prostate with a prolonged course. Also, the medication is necessary to alleviate the manifestations of renal colic.

In gynecology, Mydocalm is used to relieve pain during menstruation. It is also recommended as an antispasmodic when there is a threat of miscarriage in the first trimester of pregnancy. In gastroenterology, it is used to relieve pain and relieve spasms when other groups of drugs are ineffective. This phenomenon is possible with exacerbation of cholelithiasis.

Analogues of Mydocalm

Level 4 ATC code matches:
Tizanil

Tizanidine

Tolperisone-OBL

Tizalud

Baklosan

Sirdalud

Baclofen

Analogs of Mydocalm are drugs that have pharmacological properties similar to it, but contain a different active substance and are characterized by a different mechanism of action.

Analogues of the drug include:

• Sirdalud (active substance: tizanidine );
• Miolgin (active ingredients: paracetamol and chlorzoxazone );
• Lexotan (active ingredient: bromazepam );
• Baclofen and others.

The average price of analogues on the Ukrainian market varies from 65 to 140 UAH. In Russia they can be purchased for an average of 220-380 rubles.

• Sirdalud tablets is 110 UAH/220 Russian rubles;
• the average cost of a package of Miolgin is 140 UAH;
• Baclofen tablets is 65 UAH/230 Russian rubles.

Which is better: Sirdalud or Mydocalm? Baclofen or Mydocalm?

There is no clear answer to this question, since each of the drugs has its own advantages.

If we compare Mydocalm with Sirdalud, then both drugs belong to the same pharmacotherapeutic group, but they contain different substances as active ingredients. Mydocalm was released onto the pharmaceutical market a little earlier and therefore has been studied better than its analogue.

Mydocalm is characterized by a wider spectrum of action, but, unlike Sirdalud, it provokes fewer unwanted side reactions.

Mydocalm: analogues, price, reviews

Analogs of Mydocalm are available in most pharmacies. The network of suppliers of this drug is extended throughout Russia and the CIS countries. The price range fluctuates within acceptable limits, from affordable for 200 to more expensive for 600 rubles. The cost of the drug depends on the country of manufacture, composition and release form - a regular tablet or injection.

A list of inexpensive analogues available in terms of price and availability - substitutes for Mydocalm.

• 
  Baklosan

  – a product made in Poland.

The Polish pharmaceutical company produces the drug for patients who suffer from multiple sclerosis, diseases of the spinal cord that are of infectious, traumatic or degenerative origin. The list is complemented by cerebral palsy, meningitis, and traumatic brain injury.

You should not use Mydocalm tablets without consulting a doctor, especially for people suffering from various types of allergies, those prone to allergies to medications, patients with epilepsy, as well as those who have severe kidney disease. The drug is completely contraindicated for pregnant and breastfeeding women. Baklosan is not recommended for elderly patients and children under 12 years of age.

Side effects during treatment with Baklosan are described in the instructions for the drug: gag reflexes, sleepiness, fatigue, difficulty defecating and urinating, diarrhea, and low blood pressure.

• 
  Sirdalud

  - Swiss drug.

The Swiss analogue provides the opportunity to completely or partially relieve muscle spasms in pathologies of the spine, in particular osteochondrosis. The list of indications for use includes: sclerosis, chronic myelopathy, cerebral circulatory disorders, stroke, and paralysis.

Sirdalud should be taken with caution and only after a doctor’s prescription for those who are prone to allergic reactions to substances and for patients with liver dysfunction and disease.

Treatment with this drug may cause a number of side effects. The instructions for the drug talk about: rare heartbeat, low blood pressure, dry mouth, muscle weakness, and rapid fatigue.

• 
  Tolperisone-OBL

  - Russian analogue in an inexpensive price category.

The Russian manufacturer produces the most affordable analogue of Mydocalm, which helps treat cerebral and spinal palsy, as well as diseases associated with atherosclerosis of blood vessels and muscle spasms. Also, Tolperisone - OBL is often prescribed for post-thrombotic disorder of venous blood circulation.

Epilepsy is included in the list of indications as a side effect.

Peculiarity! Not prescribed for children under 12 months, with myasthenia gravis, pregnant women, especially in the first trimester, and those who are breastfeeding, as well as patients intolerant to certain components of the drug.

The main side effects of Tolperisone-OBL: headache, vomiting, decreased blood pressure, allergies - urticaria, itching and rash.

The drug Mydocalm is an effective drug with a wide spectrum of action. But at a fairly high price for patients with average incomes. The output is in analogues, both imported and Russian, but no less effective substitutes. All the considered substitutes are in tablet form, one of them is completely identical in composition.

Mydocalm - injections

For quick relief of pain or spasm, Mydocalm is available in ampoules. When administered intravenously, the drug begins to act faster. Mydocalm is administered intravenously very slowly by drip. The daily dose cannot exceed 100 mg. And when administered intramuscularly, the drug will have a local effect on the area of ​​the body where problems arose. Used in an amount of 100 mg 2 times a day.

Important! A prescription for the main drug and its analogue must be prescribed by a specialist doctor, focusing on the health status of a particular patient (dosage, volume and frequency of administration).

Mydocalm and its analogues occupy a stable position in the pharmaceutical market of effective drugs against pain. This is a product for which there is constant demand and a long-term positive reputation. Despite its acceptable composition and pharmacological action, you should be careful with it and take it only with a prescription.

Reviews about Mydocalm

Reviews about Mydocalm tablets left by patients who have undergone treatment with it are quite contradictory. Some note the high effectiveness of the drug, its availability and the absence of side effects.

Someone, on the contrary, points out that there were no visible results after therapy, but such phenomena as swelling , nausea or urticaria .

Most often you can find reviews about Mydocalm on forums where children's health issues are discussed. The drug is often prescribed to children diagnosed with hypertension . However, most parents do not risk giving it to children under one year old, given the age limit specified in the instructions, and limit treatment to physiotherapy and massage courses.

For this reason, there are not many positive reviews about the use of Mydocalm in children. By the way, some note as a disadvantage of the drug that the manufacturer does not have a dosage form in the form of a syrup, which would make it easier for infants to take.

Reviews from doctors about Mydocalm are positive. At the same time, most experts note that the greatest effectiveness from treatment with the drug can be achieved only by choosing the right dosage tactics, and also, in some cases, by correctly combining it with other medications.

Dependence of absorption on nutrition

The manufacturer recommends taking Mydocalm before meals . This is due to the characteristics of the pharmacokinetics of the drug. The active substance, tolperisone, is absorbed by the small intestine. The maximum concentration of the drug is achieved in the blood within an hour after use. During this time, pain associated with excessive muscle tension and spasms should subside.

Fatty foods increase the bioavailability of the drug after oral administration by almost one hundred percent. The maximum concentration in blood plasma also increases by approximately 45% compared to use on an empty stomach. When using Mydocalm tablets on an empty stomach, a delayed effect of the drug is observed - the analgesic and muscle relaxant effect develops thirty minutes longer.

Mydocalm price

How much does Mydocalm cost in tablets in Russia?

Mydocalm 50 mg No. 30 on the Russian market sells for an average of 350 rubles, the average price of Mydocalm 150 mg tablets is 400 rubles.

Cost of Mydocalm tablets in Ukraine

The price of Mydocalm 50 mg No. 30 is 180-220 UAH. The price of the drug depends on the region: for example, in Kiev you can buy the drug in this form of release for an average of 210 UAH, in Kharkov - 200 UAH, in Dnepropetrovsk - 180 UAH, the price in Odessa varies from 180 to 200 UAH .

Mydocalm 150 mg No. 30 can be purchased on the Ukrainian market for an average of 240 UAH.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Mydocalm tab.
  p.p.o. 50 mg n30Gedeon Richter-RUS ZAO RUB 340 order

Pharmacy Dialogue

• Mydocalm (tab. 50 mg No. 30)Gedeon-Richter

  RUB 377 order

• Mydocalm (tab. 150 mg No. 30)Gedeon-Richter

  417 RUR order

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PaniPharmacy

• Mydocalm tablets Mydocalm film-coated tablets 50 mg No. 30 Hungary, Gedeon Richter
  212 UAH. order
• Mydocalm tablets Mydocalm film-coated tablets 150 mg No. 30 Hungary, Gedeon Richter

  239 UAH. order

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Practical application experience

Reviews from doctors and patients who received Mydocalm injections.

My local doctor prescribed me the drug Mydocalm; I had spasticity on the left side after a stroke. To begin with, I took tablets at a dose of 50 mg, but did not feel any improvement. Then the dosage was increased to 150 mg at a time, of course, there was an effect, but I began to constantly feel sick, my appetite completely disappeared, and my blood pressure began to drop sharply.

I had to give up this form of the drug, and then the specialist prescribed me injections. Now everything is wonderful and there are no side effects and the effect is noticeable. This is a wonderful solution - injections.

Maria Yu, 49

I am 60 years old. I understand the changes that occur in the body - this is primarily age. But somehow you can support yourself.

My joints hurt, and lately I even began to limp. The doctor prescribed Mydocalm injections for me. At first I was even afraid to give such injections, I thought that they would fall asleep on the go. But the doctor insisted and now I continue to put them on. My condition has improved and I am not experiencing any adverse effects.

Nikolay K, 60

According to the results of observations, after using Mydocalm injections, a significant improvement in the patient’s condition is observed. The pain decreases, and laboratory test results return to normal.

After communicating with patients, we can often conclude that the course of therapy does not always have to be completed and the injections can be discontinued. Of course, I still recommend doing everything according to the rules.

The quality and price indicators of the medicine exceed all expected, and the product is one of the best. However, you should not engage in independent treatment; it is better to consult a specialist.

Dmitry R, ​​general practitioner

I treat the musculoskeletal system, mostly my patients are elderly people. Mydocalm is very often present in my prescriptions - the product is effective and safe when taken in the correct dosage.

Oleg G, traumatologist

From the advice of ordinary people

The drug has its advantages and disadvantages, like any other drug. It is not recommended to use the drug on your own, since only a doctor will be able to correctly diagnose and identify all possible side effects, based on the conclusions of other specialists or laboratory tests entered into the medical record.

Using the product without a doctor’s prescription can cause numerous negative reactions, in particular swelling, which will have to be relieved with the help of diuretics, which in turn also harms the body. After the first injection, you should tell your doctor about how you feel in order to make a further decision on the use of the product.