Novopassit syrup: instructions for use, indications, composition, reviews

• October 10, 2018
• Neurology
• Valieva Olga

The modern rhythm of life is closely associated with stress. The need to work, stand for many hours in traffic jams, use public transport, endure complaints from bosses and colleagues, meet society’s requirements for a “successful person” - all this inevitably leads to the development of chronic stress over time. To prevent neurotic conditions, you should use mild pharmacological sedatives as early as possible, already at the first symptoms of stress and chronic fatigue. The instructions for use for Novopassit syrup indicate that this is just such a remedy. The drug is not addictive, normalizes sleep, stabilizes the emotional state. Today it is one of the most effective and safest remedies for adults during stressful situations.

Release form and composition

Dosage forms of Novo-Passit:

• oral solution: slightly cloudy or clear, syrupy, brown to red-brown in color, with a characteristic odor; During storage, a small sediment may form, which dissolves when shaken (in sachets of 5 or 10 ml, in a cardboard pack of 12 or 30 sachets of 5 ml, 8 or 20 sachets of 10 ml; in bottles of 100, 200 or 450 ml, 1 bottle in a cardboard box);
• film-coated tablets: pale green, biconvex, oval, with a separating score (in cans of 30, 60 or 100 pcs., 1 can in a cardboard pack; in blisters of 10 pcs., 1 or 3 blisters in a cardboard pack) .

Composition per 100 ml solution:

• active ingredients: Novo-Passita liquid extract obtained from black elderberry flowers, common hop fruits, passionflower incarnate herb, St. John's wort and lemon balm, leaves and flowers of hawthorn monopistillate or prickly, rhizomes with roots of valerian officinalis - 7.75 g; guaifenesin – 4 g;
• auxiliary components: purified water, propylene glycol, maltodextrin, sodium citrate dihydrate, orange flavor, ethanol 96%, sodium saccharin monohydrate, sodium benzoate, invert sugar syrup, xanthan gum, sodium cyclamate.

Composition per 1 tablet:

• active substances: Novo-Passita liquid extract obtained from black elderberry flowers, common hop fruits, passionflower incarnate herb, St. John's wort and lemon balm, leaves and flowers of hawthorn monopistillate or prickly, rhizomes with roots of valerian officinalis - 0.157 5 g; guaifenesin – 0.2 g;
• auxiliary components: lactose monohydrate – up to 0.8 g; magnesium stearate – 0.01 g; glycerol – 0.01 g; microcrystalline cellulose – 0.096 g; colloidal silicon dioxide – 0.002 g;
• shell: Opadry AMB 80W31115 green (indigo carmine dye – 1%, yellow iron oxide – 2%, quinoline yellow dye – 2.5%, xanthan gum – 0.48%, soy lecithin – 2%, talc – 20%, titanium dioxide – 26.5%, polyvinyl alcohol – 45.52%) – 0.024 g.

Opinions about the medicine

What do doctors and patients say about such a medicine as Novopassit? Reviews from doctors confirm the high effectiveness of this medicine. Experts note that the drug perfectly relieves insomnia and night terrors. It effectively eliminates aggression, relieves irritability, and calms in stressful situations.

However, the medicine is safe for use. Due to this, patients are often prescribed the drug Novopassit. Reviews from doctors indicate that this remedy can quickly eliminate nervous excitability and alleviate the symptoms of PMS. It copes well with the blues, reduces the symptoms of depression, and relieves mild stress.

Patients also find this medication quite effective. Many people have appreciated its beneficial effects on the body. They emphasize that the drug perfectly relieves irritability, stress, and anxiety. However, many of them indicate such an undesirable manifestation as drowsiness.

People who, by the nature of their work, are under constant psychological stress, claim that they almost always carry this product with them. This allows you to take medication at any time and withstand unpleasant situations and stress with dignity.

Features of application

For children under 12 years of age, use only as prescribed by a doctor! The dose is selected individually, taking into account age and tolerance. The recommended starting dose is ½ tablet per day, before bedtime

Caution should be exercised in acute diseases of the gastrointestinal tract

During pregnancy, especially during the 1st trimester and lactation, you should consult your doctor.

The drug "Novopassit" (Novo-passit) is a combination drug that includes guaifenesin and components of plant origin.

The product has a positive effect on the nervous system: it relieves tension, reduces the level of the stress hormone (cortisol), and has an anti-anxiety effect.

Thanks to its combined composition, it has a broad integrated approach with an effective effect against nervous disorders:

The composition of the medicine includes components of plant origin:

1. St. John's wort. The plant has anxiolytic and antidepressant properties - it improves mood and reduces anxiety. In addition, it has an immunostimulating, anti-inflammatory and antispasmodic effect.
2. Hop. It has a calming, analgesic and antihistamine effect.
3. Hawthorn. It has a beneficial effect on heart rate, blood circulation in the coronary vessels and cerebral vessels, has an antispasmodic effect and reduces psychological excitability.
4. Melissa. It has a calming, antibacterial, antispasmodic, antiviral and restorative effect.
5. Black elderberry. It perfectly calms the nervous system and has an analgesic effect.
6. Passionflower. Normalizes sleep, improves concentration, has analgesic, antispasmodic and anti-anxiety effects.
7. Valerian. It has the function of mild sedation, normalizes sleep phases and reduces mental stress.
8. Guaifenesin. A substance that effectively acts on people in a state of constant stress and neurosis.

The main difference between Novo-Passit and synthetic analogues is its non-toxicity and safety in use.
With long-term use, the product will not cause you any addiction or dependence. The product is available in two dosage forms - syrup and tablets. There is a slight difference in the dosages of the components.

Composition and release form of Novo-Passit tablets

Tablets are available in strips of 10 or 30 tablets in cardboard packaging. There are official instructions inside the secondary packaging.

The tablet itself is coated on the outside with a special coating and has a characteristic plant smell. The tablets contain guaifenesin and dry plant extracts.

Composition and release form of Novo-Passit syrup

Unlike tablets, the syrup contains liquid extractants of the same plants.

This dosage form of the drug is intended for internal use. The solution looks like a cloudy liquid with a brownish or red-brown tint and a characteristic odor. After uncorking the bottle, a sediment may form during storage, which disappears when shaken.

The mixture is available in darkened glass bottles of different volumes: 100 ml, 200 ml, 450 ml.

There are official instructions inside the secondary packaging.

Afobazole

The tablets belong to the drug group of tranquilizers. The drug is used to treat mental conditions such as anxiety and tension. The active microelement "Afobazole" has an antiphobic effect and reduces anxiety. It does not affect benzodiazepine derivatives, which does not lead to drowsiness, relaxation of striated muscles, deterioration of memory and concentration. The medication does not lead to the development of drug dependence.

The active component of the tablets has an anxiolytic effect and eliminates anxiety. The drug has no effect on benzodiazepines, and therefore does not cause drowsiness, loss of memory or concentration. The drug does not lead to drug dependence.

The active microelement is instantly and completely absorbed into the blood from the lumen of the upper digestive organs. It is well distributed throughout all tissues in the body. Afobazole is excreted by the kidneys; the half-life is about 45 minutes.

The tablets are taken orally whole, after meals. The average dose of the medication is 10 milligrams three times a day. The duration of therapy varies from two to four weeks. The cost of the drug is 450 rubles.

Prescription during pregnancy

Most often, doctors do not prescribe this drug during pregnancy. This is explained by the fact that the drug can negatively affect the development of the fetus. However, there may be exceptions. The doctor may prescribe medication, but the dosage may be reduced.

Before taking Novopassit tablets (or syrup), you should interrupt lactation or express milk until the end of therapy. This is explained by the fact that a small amount of the drug passes into a woman’s milk and can cause side effects in the child.

Description of the drug

Novo-passit is available in two forms - tablets and oral solution. The latter is an alcohol-based sugar syrup. Tablets are sold in bottles and blisters. The syrup is packaged in sachets for single use and bottles with a capacity of 100-200 ml.

Novo-passit consists mainly of soothing herbs: St. John's wort, valerian, elderberry, passionflower, lemon balm, hawthorn and hops. Of the synthetic drugs, the medicine contains one substance - guaifenesin. Some of the listed components are widely used in the treatment of children, but some are strictly contraindicated until a certain age.

Indications for the use of novo-passit include various neurotic disorders. They are associated with stressful situations, overwork, and may be accompanied by anxiety, insomnia, and irritability. In children, such symptoms are often observed. It may be difficult for a child to adapt to kindergarten or school, and he may have problems sleeping. However, in these cases the drug is not prescribed.

Novo-passit is contraindicated during pregnancy and breastfeeding, with allergic reactions and certain diseases of internal organs. One of the contraindications indicated in the instructions for Novo-Passit is children under 12 years of age.

Use of Novopassit for VSD

Novopassit for VSD is prescribed to patients quite often, since the main indications for its use are:

• irritability, nervousness, anxiety;
• insomnia;
• anxiety for no reason, feeling of fear;
• headaches and dizziness;
• increased fatigue, constant feeling of tiredness;
• attention and memory disorders;
• itching on the skin caused by nervous tension.

The beneficial effect is achieved due to the complex action of the components contained in the drug.

1. St. John's wort. Improves mood, has an antidepressant effect, reduces anxiety, helps improve sleep and normalize the functioning of the gastrointestinal tract. Eliminates inflammation and spasms, has a general strengthening effect.
2. Common hops. Soothes, relieves inflammation and pain, and also has an antiallergic effect.
3. Hawthorn. Normalizes heart rhythm and has a beneficial effect on blood circulation in the brain and vascular walls. Reduces excitability.
4. Melissa. It has antibacterial, antiviral and antispasmodic effects. Helps to calm down and strengthens the body.
5. Passionflower. Increases concentration, relieves pain, improves sleep, reduces anxiety and eliminates fear.
6. Black elderberry. Soothes, relieves pain.
7. Valerian. Reduces mental stress, calms, normalizes sleep.
8. Guaifenesin. Effectively eliminates anxiety, helps with stress and neurotic conditions.

Compound

Novo-passit consists of a combination of heterogeneous components. It contains both plant substances and synthetic components. Substances of plant origin include:

• Melissa officinalis;
• Valerian officinalis;
• Prickly hawthorn;
• St. John's wort;
• Passionflower incarnate;
• Common hop;
• Black elderberry.

One substance that is synthetic is guaifenesin.

The dosage of the components in one tablet or milliliter of solution is different. One tablet contains 157.5 mg of herbal components and 200 mg of guaifenesin. In 1 ml of solution of plant components there are 77.5 mg, guaifenesin - 40 mg. In a bottle with a solution, substances may be distributed non-uniformly, so the conversion of the constituent components per 1 ml is approximate.

In addition to the main active ingredients listed, the drug includes a number of auxiliary components. The tablets contain compounds of silicon, magnesium, titanium and iron, as well as cellulose, lactose, talc, lecithin, glycerin, quinoline. The solutions contain sodium compounds, gum, ethanol, propylene glycol, maltodextrin, sugar syrup, purified water and flavoring.

Auxiliary components have no effect on the body.

Analogs

There are no complete analogues of novo-passit, but there are herbal preparations with a similar composition and mechanism of action. Such drugs include:

• Neuronorm - differs from novopassit in the absence of passionflower, St. John's wort, elderberry and guaifenesin, but contains motherwort, which is not present in novopassit;
• Persen - includes mint, lemon balm and valerian extract;
• Dormiplant - contains only mint and lemon balm;
• Relaxozan Forte - contains mint, lemon balm and valerian; there are also analogues without valerian;
• Sleep formula - the drug, like Novo-Passit, contains hawthorn, St. John's wort and hops, and in addition motherwort, magnesium and B vitamins;
• StressStop - the drug contains hawthorn, lemon balm, hops, linden and magnesium;
• Quiet solution for internal use is the most complete analogue of novo-passit, characterized by the absence of hawthorn leaves and flowers, but the presence of its extract.

All of the listed remedies are only partial analogues of Novo-Passit. These are also combined preparations from herbal components, but including and excluding several components of novo-passit. In addition, you can take any component of the drug separately. Combining them yourself is not recommended due to the difficulty of selecting the appropriate dosage.

Reviews

Diana P .: “I have a very stressful job that requires constant attention and two small children. In order to get rid of tension and become less irritable, I periodically take Novopassit. For myself, I chose the drug in syrup form because I like its pleasant smell and taste. It seems that just these two facts can lift your spirits a little. It is very easy to take using a measuring cup. I take courses as needed and have not noticed any side effects.”

Psychiatrist: “Often, people who do not have any serious mental disorders come to outpatient appointments. Their irritability, decreased attention and emotional outbursts are caused by simple fatigue. For such people, it is most effective and safe to prescribe herbal preparations such as Novo-Passit. Many patients take it in the form of syrup, since tablets are often associated with illness, but the syrup has a pleasant taste and is much more pleasant from a psychological point of view to drink than tablets.”

Content

Instructions for use of Novo-Passit: method and dosage

Oral solution

Novo-Passit solution is taken orally, pure or diluted with a small amount of water.

When using the drug in vials, dosing is carried out using a measuring cap.

When there are no other doctor's recommendations, take 5 ml of the drug 3 times a day before meals. The dose can be increased by 2 times after medical consultation.

If during the period of therapy the development of severe fatigue or depression is observed, the morning and daily dose is reduced and 2.5 ml of solution is taken in the morning and afternoon and 5 ml in the evening. An interval of 4 to 6 hours should be maintained between doses.

If nausea occurs, Novo-Passit is taken with meals.

Film-coated tablets

Novo-Passit tablets are taken orally, before meals. Recommended dose – 1 pc. 3 times a day. It is allowed to increase the dose by 2 times after consultation with a doctor.

If during the period of therapy the development of severe fatigue or depression is observed, the morning and daily doses are reduced and taken ½ pc. in the morning and afternoon and 1 pc. In the evening. An interval of 4 to 6 hours should be maintained between doses.

If nausea occurs, Novo-Passit tablets are taken with meals.

Optimal duration of treatment

Dosage for adults of Novopassit syrup: two to three measuring caps per day after the condition has leveled off, one to two caps per day. The duration of treatment is on average 2-6 weeks.

Depending on the clinical picture, the duration of the course can be increased at the discretion of the attending physician. It is prohibited to independently increase the duration of the course. If no improvements are noticeable within a week from the moment you start taking it (sleep does not normalize, irritability does not go away), then you should consult a doctor - perhaps the drug is not suitable for the patient and the terms of therapy should be reconsidered.

Composition and release form

Instructions for use for Novopassit syrup indicate that the drug is natural, and the sedative effect is achieved through herbal components:

• Valerian rhizome extract has an effect on the nervous system: it calms during excessive agitation and excitement, smoothes out the brightness of emotional reactions, and enhances inhibitory processes in brain cells. Unlike most prescription sedatives, the effects are very mild, but not unnoticeable. Valerian rhizome extract also has a moderate antispasmodic effect, so Novopassit can be used for mild pain during premenstrual syndrome.
• The extract of the medicinal plant lemon balm has a similar effect on the central nervous system.
• St. John's wort herb extract has an antidepressant and anxiolytic effect, thereby increasing the patient's mental stability during periods of chronic stress.
• Hawthorn extract improves blood circulation in the heart muscle and helps relieve symptoms of panic attacks.
• Passionflower extract has a sedative effect, in particular, it helps people who suffer from insomnia to sleep.
• Hop fruit extract helps reduce emotional stress and has a mild antispasmodic and hypnotic effect.
• Black elderberry flower extract has a moderate diuretic, anti-inflammatory and analgesic effect, and is effective against panic attacks, which manifest themselves physically as pain of unknown etiology.

The drug is available in the form of syrup, tablets and solution. The composition of Novopassit is similar, regardless of the form of release. The drug in the form of a solution contains 96% ethyl alcohol (ethanol), which accounts for about 12%.

The safe herbal composition of Novopassit allows the product to be used both independently and as part of complex therapy for the treatment of various nervous disorders and conditions in children, adolescents and the elderly. The peculiarity of the drug is that, unlike strictly prescription anxiolytics and tranquilizers, it is not addictive, and most patients do not suffer from withdrawal symptoms during the course of treatment.

Possible side effects

Unlike prescription drugs, Novopassit most often does not lead to any significant side effects. Among the most common are the following:

• from the nervous system: drowsiness (if the recommended dosage is exceeded), unfocused attention, absent-mindedness, long sleep;
• from the gastrointestinal tract: nausea, pain in the solar plexus, diarrhea;
• from the endocrine system: allergic reactions, skin rash (rare).

Forms of release of novo-passit

Novo-passit tablets

plates, that is, 10 or 30 tablets, respectively , 60 tablets each

Each Novo-Passit tablet contains:

• Guaifenesin
  – 200 mg.
• Dry plant extracts
  – 157.5 mg (
  in this case, the total mass of all the above listed plant components included in 1 tablet is denoted
  ).

Novo-passit solution

2.5 ml, 5 ml, 7.5 ml and 10 ml

5 ml of novo-passit solution contains:

• Guaifenesin
  – 200 mg.
• Liquid plant extracts
  (
  listed above
  ) – 387.5 mg.

Analogues of Novo-Passit (what can replace Novo-Passit?)

sedative, hypnotic, cardiotonic and so on

Analogues of novo-passit

Instructions for use and dosage

The drug is taken orally three times a day before meals. The standard single dose is 1 tablet. In severe cases of the disease, 2 pills are prescribed (the maximum allowable amount is 6 pieces per day).

If the patient experiences excessive fatigue and apathy, reduce the dosage to 0.5 tablets before breakfast and dinner, and drink 1 tablet at lunch. The medicine is taken with a break of 4-6 hours.

For children

For the treatment of children, the drug is used as prescribed by a doctor. Patients over 12 years of age are given 1 tablet three times a day, unless there are special indications.

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For children under 12 years of age, the doctor selects a personal dosage regimen, taking into account the developmental characteristics and condition of the patient, the severity of the disease, concomitant pathologies, and tolerability of the drug. The initial dosage is 0.5 tablets per day at night.

During pregnancy and lactation

Pregnant women are prescribed the drug when the expected positive effect is higher than the probable risks for the child. If there is a need to use Novo-Passit for the treatment of lactating women, breastfeeding is interrupted for the duration of use.

Overdose

The duration of therapy and dosage of the product can only be adjusted by a doctor. Violating the rules for taking the drug can lead to serious complications. In some cases, they develop already against the background of a single dose of triple the standard amount of the drug. If at least one of the alarming symptoms appears, you must call an ambulance. Before its arrival, it is recommended to rinse the victim’s stomach, and then give activated carbon in the amount of 1 tablet per 10 kg of body weight.

An overdose of Novopassit is characterized by the following symptoms:

• pathological drowsiness - appears suddenly and gradually increases if no action is taken;
• lethargy – as a result of central nervous system depression, the patient’s attentiveness decreases and reactions slow down;
• depression - a person reacts poorly to external stimuli, is not interested in anything, feels emotional emptiness;
• decrease in muscle strength - may have varying degrees of severity, some patients lose the ability to do usual activities;
• nausea, vomiting - occur in response to irritation of the gastrointestinal mucosa or become an attempt by the body to get rid of the irritant.

It is not recommended to take the medicine for longer than the time prescribed by your specialist. The drug increases the strength of heart contractions, reducing their frequency. This can be dangerous for people with bradycardia and low blood pressure.

What kind of drug is Novo-Passit?

Novo-passit

Composition and mechanism of action of novo-passit

The active components of novo-passit are:

• Valerian officinalis rhizome extract.
  The essential oils, tannins and organic acids contained in the plant have a special effect on the central nervous system (
  in particular on the nerve cells of the brain
  ), enhancing the inhibitory processes in them.
  This leads to a decrease in the excitability of the central nervous system
  ), as a result of which phenomena such as agitation, anxiety, nervousness, and so on disappear, that is, the person calms down.
  As a result of all this, the process of falling asleep is easier, especially if before this the person has not slept for a long time due to increased nervous excitability. It is also worth noting that the extract of valerian rhizomes has a certain antispasmodic effect ( that is, it relaxes excessively contracted muscles of the internal organs
  ), which improves blood circulation in them.
• Lemon balm herb extract.
  The effects of lemon balm at the central nervous system level are similar to those of valerian.
  The drug enhances inhibitory processes in the brain, thereby reducing increased nervous excitement and facilitating the process of falling asleep, as well as providing a certain anxiolytic effect ( reduces anxiety, restlessness and other experiences caused by various stressful situations
  ). In addition, lemon balm extract has a certain antidepressant effect, that is, it improves mood if a person is depressed or upset. Melissa, like valerian, has an antispasmodic effect.
• St. John's wort herb extract.
  It has a beneficial effect on many parts of the central nervous system, providing a sedative, antidepressant and anxiolytic effect. Eliminates increased nervous excitement, improves mood, normalizes sleep and increases the patient's mental stability.
• Extract of leaves and flowers of hawthorn monopistillate.
  Improves blood circulation in the myocardium (
  heart muscle
  ), and also enhances the contractility of the heart.
  In addition, the drug has a moderate calming effect and also reduces excessively high blood pressure ( especially if it has increased as a result of a stressful situation
  ).
• Extract of passionflower herb (
  passion flower ).
  Has a calming and mild hypnotic effect.
• Common hop fruit extract.
  It has a calming, antispasmodic and mild hypnotic effect, and also improves the functioning of the cardiovascular system.
• Black elderberry flower extract.
  It has anti-inflammatory, mild analgesic and mild diuretic effects.
• Guaifenesin.
  A pharmacological drug that has a moderate anxiolytic effect. As part of combination therapy, it is used to treat various neuroses and anxiety conditions.

improving the functioning of the cardiovascular system

Pharmacodynamics

The pharmacological properties of novo-passit are associated with the effect on the body of each of the components that make up its composition. The most studied of all components is the synthetic component of novo-passit - guaifenesin.

Guaifenesin was developed as a mucolytic agent. Its mechanism of action is based on thinning sputum and improving its elimination; the drug is used for productive cough. In fact, guaifenesin is still an ingredient in many cough medications. However, post-marketing studies have shown that guaifenesin not only combats phlegm, but also reduces anxiety.

Plant components have been studied in less detail. They are applied largely empirically. The following is known about each of the plant components:

• Melissa is a sedative used for neurotic conditions. In addition, it has hypotensive, antiarrhythmic, vasodilating, antispasmodic and antiseptic effects.
• Valerian - has a relatively unexpressed sedative, antispasmodic and antihypertensive effect. Its value lies in potentiating the action of other sedative components. Valerian increases the effectiveness of other components.
• Hops is a sedative component that helps cope with insomnia, is an analgesic and antispasmodic. In addition, it contains large amounts of vitamin C, a natural antioxidant.
• Passionflower is a mild herbal tranquilizer that is also used to treat arrhythmias and asthma. In many collections it is used together with valerian and St. John's wort, since the latter enhance its effect on the body.
• St. John's wort - has a calming and hypnotic effect due to its antioxidants and cineole. In addition, it contains several antioxidants and has antimicrobial, choleretic and anti-inflammatory effects. Increases skin sensitivity to ultraviolet radiation.
• Hawthorn - has sedative properties due to the saponins and choline it contains. In addition, it contains vitamins, metabolic substances, helps reduce blood cholesterol levels, and has a diuretic effect.
• Elderberry is a mild sedative and hypnotic. By itself, it has little effect on the nervous system, but enhances the effect of other components. It has a pronounced anti-inflammatory, antimicrobial and analgesic effect.

Thus, all of the listed components, in addition to the sedative, anti-anxiety and hypnotic effect, have a number of other properties, which helps to generally normalize the body’s activity.

Kinetic studies cannot be carried out, because The effect of the medication is due to the combined effect of all its constituent components.

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Indications for use

• neurasthenia in a mild form, which is accompanied by fear, anxiety, irritability and impaired concentration;
• insomnia;
• impotence and chronic fatigue, memory impairment of neurotic origin;
• in complex therapy in the treatment of episodic and acute attacks of headaches and migraines, the etiology of which is the cause of nervous overstrain;
• vascular disorders (VCD), psychosomatics, neurogenic convulsions, disorders of the innervation of the trigeminal nerve, which lead to facial pain;
• menopause;
• complex therapy in the treatment of gastrointestinal tract organs of neurotic origin;
• dermatoses of a psychosomatic nature (itching, eczema, urticaria).

Contraindications

• age up to 12 years;
• muscle weakness caused by pathological agents;
• individual allergic manifestations to components;
• liver diseases;
• alcoholism in chronic form;
• GM injuries;
• exacerbation of chronic gastrointestinal diseases.

The drug should not be used if:

During pregnancy and lactation, the drug should be used strictly as prescribed by a doctor.

The manufacturer advises not to drink alcohol during the period of treatment with the drug.

Side effects:

1. Immune system: destruction of blood vessels (vasculitis), hypersensitivity to components.
2. Nervous system: depression, noise and dizziness, weakness and drowsiness, apathy.
3. Digestive system: dyspeptic symptoms (vomiting, upset, heartburn, etc.)
4. Skin and pancreas: swelling of the skin, redness, itching, rashes, photosensitivity.
5. Musculoskeletal system and connective tissue: myasthenia gravis.
6. Respiratory system: difficulty breathing.
7. Cardiovascular system: hypertension, cardiac arrhythmia (tachycardia or bradycardia).

Interaction

The simultaneous use of Novopassit with other medications may affect the severity of the effect of the latter. For this reason, it is not recommended to start taking a sedative while taking any medications until you have received permission from your doctor.

Interaction with other drugs can give the following results:

• muscle relaxants – increases the risk of developing muscle weakness;
• drugs with ethanol – central nervous system depression;
• hormonal contraceptives – the effectiveness of contraceptives is reduced;
• immunosuppressants – the effect of the products is weakened;
• anticoagulants, heart medications, medications for the treatment of AIDS - the results of using the products change or decrease.

Novopassit can be taken in combination with most other sedatives of natural and chemical nature. Dosages, schedules, combinations should be selected by a doctor.

special instructions

Despite the fact that Novo-Passit is a herbal medicine, certain precautions must be taken when taking it. First of all, the drug should not be taken together with alcoholic beverages.

That is why alcoholism is a contraindication to prescribing the drug. This is due to the fact that some of the components are not compatible with ethyl alcohol. You should learn more about drinking alcohol together with Novo-Passit.

Novo-passit should not be taken with grapefruit juice. It has been proven that this particular juice enhances the toxic effect of St. John's wort on the liver. While taking Novo-Passit, you should avoid grapefruit altogether. In addition, St. John's wort is metabolized in the liver using enzymes of the cytochrome system. Most drugs bind to these same enzymes. Therefore, Novo-Passit should not be taken by people who take digoxin, warfarin, benzodiazepine tranquilizers, tricyclic antidepressants and selective serotonin reuptake inhibitors.

Guaifenesin, which is part of novo-passit, can change the results of some laboratory tests. That is why, if it is necessary to donate blood or urine, Novo-Passit should be canceled at least two days before collecting biological materials.

Compatibility with alcoholic drinks

Ethyl alcohol, which is part of any alcoholic beverage, is itself a fairly powerful sedative and depressant. Despite the fact that a course of taking Novopassit syrup during withdrawal symptoms can significantly alleviate the condition of the patient’s nervous system, direct combination of syrup with alcoholic beverages should be avoided.

Depending on the amount of syrup drunk and the dosage, a rather deep sleepy state may develop, lasting from 12 to 14 hours. It is dangerous because when vomit is expelled (which is normal for any poisoning), a person may not wake up, resulting in death from asphyxia due to obstruction of the respiratory tract.