The drug Kalcemin: instructions, dosage and side effects

Composition of Kalcemin

1 tablet contains calcium citrate and - 0.25 g, vitamin D3 (cholecalciferol) - 50 IU, zinc - 2 mg, manganese sulfate - 500 mcg, boron - 50 mcg, copper - 500 mcg.
Additional substances: microcrystalline cellulose, stearic acid, maltodextrin , magnesium stearate , crocscarmellose ; The shell contains the following composition: hypromellose , silicon and titanium dioxide, magnesium silicate, mineral oil.

Calcemin Silver contains calcium 500 mg, vitamin D3 – 400 IU, magnesium 40 mg, copper oxide – 1 mg, manganese 1.8 mg, boron – 250 mcg, zinc 7.5 mg.

Citra-Calcemin contains calcium in the form of citrate - 250 mg, vitamin D3 - 125 IU, magnesium 40 mg, boron - 0.25 mg, manganese - 0.5 mg, zinc - 3.75 mg, copper - 0.5 mg.

Pharmacological properties

Pharmacodynamics

The action of Calcemin is due to the properties of its constituent components.

Calcium takes part in the formation of bone tissue, increases its density and reduces resorption (resorption), and also helps strengthen joints and the skeletal system and prevents diseases of the musculoskeletal system.

Calcium citrate has the following effects on the body:

• ensures the absorption of calcium even in conditions of disruption of the normal functioning of the gastrointestinal tract (for example, with a decrease in secretory function and during the period of taking drugs to reduce secretion);
• regulates the level of parathyroid hormone, thus improving the regulation of calcium homeostasis;
• slows down the processes of bone tissue destruction.

Also, this substance does not increase the content of calcium and oxalates in the urine (does not lead to the formation of kidney stones) and does not block the absorption of iron (does not cause iron deficiency anemia).

Vitamin D3 is involved in the regulation of phosphorus and calcium metabolism, the formation of the bone skeleton, ensures the preservation of bone structure, enhances the processes of calcium absorption in the intestine and phosphorus reabsorption in the renal tubules.

Zinc regulates the formation of sex hormones and slows down the process of bone tissue destruction.

Manganese takes part in the synthesis of proteoglycans, forms the protein matrix of bone tissue and improves its quality.

Boron reduces excessive activity of parathyroid hormone and the risk of developing cholecalciferol deficiency, improves calcium absorption and reduces the likelihood of developing osteoporosis.

Copper takes part in the production of collagen and elastin, which is part of connective and bone tissue.

Instructions for use of Calcemin (Method and dosage)

Children over 12 years of age and adults - 2 tablets per day in 2 divided doses.

Children from 5 to 12 years old take 1 tablet. per day.

Take the medicine with food.

If there is a lack of trace elements and calcium in the body, use 1 tablet per day.

The instructions for Kalcemin provide clear instructions on how to take the medicine for pregnant women: use begins in the 2nd half of pregnancy (not earlier than the 20th week ) and continues throughout breastfeeding at a dose of 1 tablet twice a day.

The instructions for Citra-Calcemin indicate that the drug is a dietary food supplement and is not a drug.

Contraindications

Before starting to use this drug, the patient is recommended to consult a doctor, since not all people are allowed to take Calcemin due to the following contraindications:

• Individual intolerance to the components included in the medication;
• The patient has a history of allergic reactions to similar drugs;
• Elevated levels of calcium in the blood;
• Tumors (myeloma, sarcoidosis, bone metastases);
• Children under 5 years of age (up to 12 if Calcemin Advance is prescribed);
• Hypervitaminosis D3;
• Urolithiasis disease;
• A metabolic disorder was recorded;
• Formation of calcifications in the gallbladder ducts or pancreas;
• Severe liver and kidney diseases, accompanied by significant deterioration in organ function;
• Tuberculosis (active form).

With caution and under the supervision of a doctor, it is possible to take it if you have a history of:

• Benign granulomatosis;
• Taking cardiac glycosides;
• A course of thiazide diuretins;
• Pregnancy at all stages;
• Lactation period.

Analogues of Kalcemin

There are no structural analogues. Preparations with a similar composition: Beresh Calcium plus D3 , Calcium D3 Nycomed , Osteokea , Vitrum Calcium D3 .

The price of analogues ranges from 269 rubles. up to 581 rub. depending on the manufacturer and quantity in the package.

Calcemin or Calcium D3 Nycomed – which is better?

Calcium D3 Nycomed contains a higher dosage of vitamin D3 and calcium, but there are no additional microelements (zinc, boron, copper, magnesium). It also contains aspartate , which is not recommended for pregnant women. The cost of the drugs is practically the same.

What is the difference between Calcemin and Calcemin Advance?

The difference lies in the larger dose of the main components in Advance . For example, there is 2 times more calcium, and 4 times more vitamin D3.

How effective is the medicine?

This drug is highly effective due to the sufficient amount of calcium it contains. Calcium plays an important role for the human body, so if it is deficient, it needs to be replenished with this microelement.

However, do not forget that excess calcium in the body can lead to adverse consequences. You should not consume Calcemin at will. A doctor's prescription must be obtained to take calcium supplements.

Uncontrolled use of Calcemin and its analogues is strictly prohibited. According to doctors, the drug is well tolerated by the human body and can be used by both pregnant and lactating women. For some diseases, the drug is indicated for use even in children. But before treatment, you must consult your doctor.

Reviews about Kalcemin

There are many reviews that these are good vitamins for hair and nails. By taking the drug, you can perfectly strengthen flaking and thin nails, as well as accelerate hair growth. Many people use the medicine if they have to take medications for a long time that wash away calcium from the bones.

Numerous reviews of Calcemin during pregnancy indicate that it can actually prevent tooth decay and replenish calcium deficiency. In general, reviews from doctors indicate that the drug has become widespread among them for use during pregnancy in order to prevent muscle cramps in pregnant women and calcium deficiency in both mother and child. Moreover, this is perhaps the only calcium supplement that does not contain aspartame , an excess of which can cause a decrease in intelligence in children, and therefore is also safe for the child.

There are also positive reviews about Kalcemin Silver as a drug that has a good effect in healing fractures .

There are not very many reviews on Citra-Calcemin, but mostly good, as a drug for strengthening hair and nails. The disadvantage is the large size of the tablets, which are difficult to swallow or chew.

Overdose

In case of an overdose of the drug, the development of vitamin D hypervitaminosis, hypercalcemia and hypercalciuria is possible. Main symptoms: thirst, nausea, loss of appetite, vomiting, constipation, polyuria, fainting, dizziness.

Long-term use of excessive doses can cause the development of calcification of tissues and blood vessels. If the described symptoms appear, it is recommended to reduce the dose of the drug or stop taking it. In case of accidental overdose, it is necessary to induce vomiting, perform gastric lavage and carry out symptomatic therapy.

Calcemin price, where to buy

The cost of the drug in Russia depends on packaging - the price of 30 pieces ranges from 178 to 227 rubles, 60 tablets costs 274 - 348 rubles, and for a package of 120 tablets you need to pay from 422 to 494 rubles.

How much does the medicine cost in Moscow? Average price 30 pcs. 192 rubles, and a bottle with 120 tablets. costs 456 rubles.

In Ukraine you can buy Kalcemin Silver for 64 UAH. 30 tablets for 100 UAH. 120 tablets.

The average price of Citra-Calcemin is 43 UAH. 30 pieces and 62 UAH. 60 tablets.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Calcemin tablets p.p.o.
  120 pcs. Sagmel Inc/Contract Pharmacal Corporation RUR 759 order
• Calcemin tablets p.p.o. 60 pcs. Sagmel Inc/Contract Pharmacal Corporation

  500 rub. order

• Calcemin tablets p.p.o. 30 pcs. Sagmel Inc/Contract Pharmacal Corporation

  RUR 348 order

• Calcemin Advance tablets p.p.o. 30 pcs. Sagmel Inc/Contract Pharmacal Corporation

  RUR 458 order

• Calcemin Advance tablets p.p.o. 60 pcs. Sagmel Inc/Contract Pharmacal Corporation

  RUR 561 order

Pharmacy Dialogue

• Calcemin (tablet. No. 30)Contract

  RUB 367 order

• Calcemin Advance tablets b. #60Sagmel Inc.

  RUB 894 order

• Calcemin (tablet p/o No. 120)Contract

  RUR 793 order

• Calcemin Advance tablets No. 30Contract

  RUR 499 order

• Calcemin (tablet. No. 60)Contract

  RUR 504 order

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Pharmacy24

• Citra-Calcemin N60 tablets Mission Famekl Company, USA
  102 UAH.order
• Citra-Calcemin N30 tablets Mission Famekl Company, USA

  69 UAH order

• Calcemin Advance N60 tablets Contract Pharmacal Corporation, USA

  150 UAH order

PaniPharmacy

• Citra-calcemin tablet. No. 30, Mission Pharmacal Company

  78 UAH order

• Citra-calcemin tablet. No. 60, Mission Pharmacal Company

  122 UAH order

• Calcemin Advance film-coated tablets No. 60, Contract Pharmacal Corporation

  157 UAH order

• Calcemin Advance film-coated tablets No. 30, Contract Pharmacal Corporation

  95 UAH order

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Adverse reactions

The drug, if the dose is observed, is well tolerated by most patients. Rarely may occur:

• nausea, vomiting;
• unstable stool;
• abdominal pain, bloating;
• rashes, redness on the skin, itching.

In case of overdose the following appears:

• weakness,
• headache,
• loss of appetite,
• dizziness,
• short-term loss of consciousness,
• bone pain,
• heart rhythm disturbances,
• tendency to constipation.

If you take high doses for a long time and uncontrollably, calcium is deposited in organs and artery walls, and blood circulation worsens. An extremely high level of calcium salts leads to a comatose state with a fatal outcome.

Interaction with other drugs

Vitamin A taken during therapy reduces the toxicity of vitamin D3.

The effect of vitamin D3 is weakened by phenytoin, barbiturates, glucocorticoids, and laxative medications reduce its absorption.

Glucocorticoids, oral contraceptives, levothyroxine impair the absorption of calcium ions.

When prescribed in parallel with tetracycline, the difference between taking it with Calcemin should be at least 3 hours, with bisphosphonates and sodium fluoride - at least 2 hours (their absorption worsens).

When prescribing Calcemin with cardiac glycosides, the toxicity of the latter increases, so you need to monitor the patient’s well-being and do an ECG.

When prescribed in combination with thiazide diuretics, the risk of hypercalcemia increases; with furosemide and other “loop” diuretics, the excretion of calcium in the urine increases.

Calcemin is not recommended to be taken in combination with calcium channel blockers, as well as with antacids containing aluminum, since in this case the effectiveness of therapy is reduced.