Pantogam active - description of the drug, instructions for use, reviews

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Manufacturers: TsNKB FSUE (Russia), PIK-PHARMA PRO LLC (Russia)

Active ingredients

  • Not indicated. See instructions

Disease class

  • Schizophrenia
  • Neurotic disorder, unspecified
  • Mental retardation, unspecified
  • Specific developmental disorders of speech and language
  • Specific developmental disorders of learning skills
  • Specific developmental disorders of motor function
  • Impaired activity and attention
  • Tics unspecified
  • Enuresis of inorganic nature
  • Stuttering [stammering]
  • Huntington's disease
  • Parkinson's disease
  • Other extrapyramidal and movement disorders
  • Myoclonus
  • Extrapyramidal and movement disorder, unspecified
  • Epilepsy, unspecified
  • Vascular cerebrovascular syndromes in cerebrovascular diseases (I60-I67*)
  • Cerebral palsy
  • Cerebral atherosclerosis
  • Cerebrovascular disease, unspecified
  • Brain disorder in newborn, unspecified
  • Excessive activity
  • Consequences of intracranial injury
  • Antipsychotic and neuroleptic drugs
  • Other types of malnutrition
  • Neurogenic bladder weakness, not elsewhere classified

Clinical and pharmacological group

  • Not indicated. See instructions

Pharmacological action

  • Nootropic
  • Anticonvulsant

Pharmacological group

  • Nootropics

Analogues of the drug according to ATC codes:

VINPOTROPIL GLYCINE CALCIUM HOPANTHENATE COGITUM COMBITROPIL CORTEXIN CORTEXIN MINISEM NOOCLERIN NOOPEPT OMARON PANTOGAM PANTOGAM PANTOCALCIN PIRACESIN PIRACETAM + CINNARIZIN SEMAX PHESAM PHENOTROPIL CEREBROLYSATE CEREBRUS CEREBROLYSIN OLYSATE CYTOFLAVIN All

Interaction with other pharmaceuticals

When prescribing Pantogam active, you should remember that the medicine:

  • Extends the effect of barbiturates on the body.
  • Strengthens the anticonvulsant effect of medications taken.
  • Prevents the development of adverse reactions during treatment with Neuroleptics, Carbamazepine, Phenobarbital.
  • Potentiates the therapeutic effect of local anesthetics (procaine).

When used simultaneously with etidronic acid and glycine, the effect of taking the drug is enhanced.

Release form, composition and packaging

Hard gelatin capsules, size No. 1, yellow; the contents of the capsules are white or white powder with a yellowish tint.

1 caps.
D,L-hopantenic acid200 mg

Excipients: microcrystalline cellulose - 13.98 mg, magnesium stearate - 1.02 mg.

Composition of the capsule shell: gelatin, glycerol (glycerin), nipagin (methyl parahydroxybenzoate), nipazole (propyl parahydroxybenzoate), sodium lauryl sulfate, purified water, titanium dioxide, yellow iron oxide.

10 pieces. — contour cell packaging (6) — cardboard packs. 15 pcs. — contour cell packaging (4) — cardboard packs. 60 pcs. — polymer jars (1) — cardboard packs.

Hard gelatin capsules, size No. 0, white; the contents of the capsules are white or white powder with a yellowish tint.

1 caps.
D,L-hopantenic acid300 mg

Excipients: microcrystalline cellulose - 20.97 mg, magnesium stearate - 1.53 mg.

Capsule shell composition: gelatin, glycerol (glycerin), nipagin (methyl parahydroxybenzoate), nipazole (propyl parahydroxybenzoate), sodium lauryl sulfate, purified water, titanium dioxide.

10 pieces. — contour cell packaging (3) — cardboard packs. 10 pcs. — contour cell packaging (6) — cardboard packs. 15 pcs. — contour cell packaging (2) — cardboard packs. 15 pcs. — contour cell packaging (4) — cardboard packs. 30 pcs. — polymer cans (1) — cardboard packs. 50 pcs. — polymer jars (1) — cardboard packs.

Instructions for use and dosage (adults, elderly, during pregnancy and lactation, children)

Pantogam Active is taken orally a third of an hour after eating breakfast and lunch twice a day. It is preferable to use in the morning and before bed. Take 1-4 capsules 200 mg. The maximum daily dosage is 12 capsules.

Take 300 mg capsules up to three times a day. The maximum number of capsules per day is 8 pieces. The duration of therapy is from one month to four. Sometimes the course can be extended to six months or even a year. After 3 months, you can do another course of treatment.

Pantogam Active is prohibited for use in children under 18 years of age. It is also prohibited to take during pregnancy and lactation. Or stop breastfeeding for the duration of treatment.

Approved for use in older age groups. The dosage is the same as for adults.

pharmachologic effect

The action of Pantogam active is associated with the presence of gamma-aminobutyric acid in its structure, which directly affects the GABAB receptor-channel complex. Pantogam active is a racemic mixture of equal amounts of the R-form of hopantenic acid and its S-isomer. The presence of the isomer improves the transport and interaction of the drug with the GABA receptor. Pantogam active has a more pronounced nootropic and anticonvulsant effect than first-generation hopantenic acid preparations.

Pantogam active increases the brain's resistance to hypoxia and the effects of toxic substances, stimulates anabolic processes in neurons, and combines a moderate sedative effect with a mild stimulating effect. It has antiasthenic and mild anti-anxiety effects. Reduces motor excitability, streamlines behavior. Activates mental activity and performance. Causes inhibition of the pathologically increased bladder reflex and detrusor tone.

Side effects

The use of Pantogam syrup, as well as tablets, is often accompanied by unwanted reactions. If they occur, you should stop taking the drug and visit the doctor who prescribed it. The side effects listed below are ranked according to frequency of occurrence, ranging from very common to very rare:

  • The immune system. Various allergic manifestations: skin rashes like urticaria, inflammation of the nasal mucosa, accompanied by swelling, congestion, serous secretion, conjunctivitis.
  • Mental disorders. Sleep disorders, in isolated cases drowsiness is observed.
  • CNS. Headache, noise or buzzing in the head, dizziness.
  • Digestive system. Nausea, pain in the upper abdomen.

It is worth noting that undesirable effects may not appear immediately; their occurrence depends on the individual characteristics of the body.

Indications

  • cognitive impairment in organic brain lesions (incl.
  • consequences of neuroinfections and traumatic brain injuries) and neurotic disorders;
  • cerebrovascular insufficiency,
  • caused by atherosclerotic changes in cerebral vessels;
  • extrapyramidal hyperkinesis (myoclonus-epilepsy,
  • Huntington's chorea,
  • hepatolenticular degeneration,
  • Parkinson's disease and others),
  • as well as for the treatment of extrapyramidal syndrome,
  • caused by taking antipsychotics;
  • for epilepsy together with anticonvulsants;
  • psycho-emotional overload,
  • decreased mental and physical performance,
  • to improve concentration and memory;
  • neurogenic urinary disorders (pollakiuria,
  • imperative urges,
  • urge urinary incontinence,
  • enuresis);
  • for schizophrenia in complex therapy.

Pantogam asset

Active substance:

D,L-hopantenic acid

Pharmgroup:

Nootropics

Average price in pharmacies

NameManufactureraverage price
Pantogam 0.1/ml 100ml syrupPIK-PHARMA439.00
Pantogam 0.25 n50 tabPIK-PHARMA423.00
Pantogam 0.5 n50 tabPIK-PHARMA666.00
Pantogam active 0.3 n60 capsPIK-PHARMA523.00

Analogs for the active substance:

No data on synonyms

Application area:

Wilson-Westphal-Konovalov disease

Wilson-Konovalov disease

Wilson's disease

Wilson-Konovalov syndrome

Impact of stress factors

Impact of extreme situations

Secondary disorders of mnestic functions

Secondary neurotic symptom

Huntington's disease (chorea)

Hepatolenticular degeneration

Hepatocerebral dystrophy

Rheumatic hyperkinesis

Choric hyperkinesis

Hyperkinesis of central origin

Hyperkinesis

Brain hypoxia

Yuppie flu

Diabetic asthenia

Hepatocerebral dystrophy

Encephalopathy

Prolonged emotional stress

Daytime enuresis

Other neurotic conditions

Diseases of the brain of a vascular and age-related nature

Forgetfulness

Urinary retention

Difficulty concentrating

Difficulty in mental functioning

Difficulty urinating

Obstructed urine flow

Idiopathic bladder instability

Intellectual disability

Intellectual-mnestic disorder

Intellectual-mnestic disorder

Mental infantilism

Exhaustion of the nervous system

Physical exhaustion

Cognitive impairment

Coma due to cerebrovascular accident

Correction of side effects of neuroleptics

Correction of side effects of neuroleptics

Lacunar status

Congenital copper toxicosis

Menkes disease

Metabolic and vascular disorders of the brain

Memory impairment

Intellectual impairment

Impaired blood supply to the brain

Violation of mnestic functions

Cerebrovascular accident

Urinary dysfunction

Urinary dysfunction

Violation of mental activity

Thinking disorder

Impaired bladder emptying

Disturbance of urine outflow

Memory impairment

Impaired mental performance

Brain dysfunction

Dysfunction of the cerebral cortex

Cerebral circulation disorders

Impaired thinking function

Thinking disorders

Memory disorders

Neurosis

Neurosis with increased irritability

Neuroses

Neuroses of all kinds

Neuroses with retardation

Neuroses of the heart

Neurotic disorders in alcoholism

Neurotic disorders with retardation

Neurotic disorders with anxiety syndrome

Neurotic reactions

Neurotic symptoms in alcoholism

Neurotic conditions

Neurotic syndrome

Neurotic disorder

Urinary incontinence

Malaise

Cerebrovascular insufficiency

Neuroleptic extrapyramidal syndrome

Neuropsychic stress

Nervous exhaustion with depression

Nocturia

Nocturnal polyuria

Nocturnal pollakiuria

General mental fatigue

General weakness

General physical fatigue

General malaise

Weakening intellectual productivity

Memory loss

Residual effects of traumatic brain injury

Acute intoxication with antipsychotic drugs

Acute cerebrovascular insufficiency

Acute polyuria

Acute cerebrovascular accident

Mental retardation

Memory decline

Parkinsonism of vascular origin

Pathological fatigue

Primary disorders of mnestic functions

Side effects of neuroleptics

Increased fatigue

Increased fatigue

Pollakiuria

Pollakiuria and nocturia

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