Who is Coaxil intended for?
Serotonin plays an important role in the enteric nervous system in the intestinal tract, where it controls intestinal secretions and the movement of digestive material.
Analysis of the results of large-scale epidemiological surveys has shown that anxiety disorders are widely associated with severe depression. This makes an antidepressant with anxiolytic properties particularly unique and attractive.
Coaxil is effective in reducing depressive symptoms of mild depressive disorder and also relieves anxiety symptoms associated with depression.
Doctors usually prescribe Coaxil for depression or anxiety disorder. Some health care providers prescribe Coaxil along with other medications and therapies to treat these conditions. Treatment of severe depression with Coaxil results in greater improvements in neurocognitive function, especially in the areas of error making and verbal immediate memory.
Coaxil has various effects on the body, including increased motivation, suppression of anxiety, cognitive euphoria, increased concentration, rejuvenation and cognitive fatigue.
Impact on the body
The main effect of the drug is:
- improvement of somatic status: pain, fever, nausea, dizziness decrease;
- positive impact on those suffering from withdrawal symptoms when withdrawing from alcohol;
- stimulation of the nervous system to increase performance and mental activity;
- sedative effect - the drug calms and relaxes, reduces fears, alleviates depression, and so on.
The peculiarity (and even uniqueness) of the medicine lies in its double effect - both stimulating and calming. The patient’s concentration and memory do not suffer, activity does not decrease, there is no deterioration in sleep, but depressive thoughts and depression go away, the patient’s mood improves, the patient’s appetite and general condition improve. When taken correctly, Coaxil does not affect the cardiovascular system, and its effect is very striking. This is where the danger lies: patients, reassured by the harmlessness of the drug, begin to take it uncontrollably and become dependent on it.
What is the effect of Coaxil and how quickly will remission occur?
Coaxil is as effective as several classical antidepressants for patients with severe depression, dysthymia, or adjustment disorder. In addition, long-term treatment with Coaxil reduces the incidence of relapse/relapse of depression.
Coaxil has a relatively favorable pharmacokinetic profile. It is not subject to primary hepatic metabolism, has high bioavailability and limited distribution, and is quickly eliminated from the body. Although this provides advantages of Coaxil over tricyclic antidepressants in terms of dose titration, treatment modification, and potential drug interactions, its rapid elimination makes medication and dosage compliance more important.
History of origin
Coaxil appeared as a medicine in Russia in the early 90s. Thanks to a wide advertising campaign, by 2006 it became the most prescribed antidepressant by doctors. Until 2002, it was on the list of vital and essential drugs. It was only in 2010 that Coaxil was recognized as a full-fledged drug and its sales were strictly registered. Unfortunately, the psychotropic properties of the drugs were discovered by drug addicts long before the measures were taken. During their free time selling, many people became addicted to Coaxil.
How to take Coaxil for depression: dose and frequency of use
Tablets should be taken orally, before meals, 12.5 mg 3 times a day (for patients over 70 years of age and with renal failure - 2 times a day), swallowed whole and washed down with plenty of water.
Tell your doctor if you are taking any other psychiatric or antidepressant medications or if you are taking medications for migraines.
Continue taking Coaxil as directed and tell your doctor if your symptoms do not improve.
Do not stop using Coaxil suddenly, otherwise you may experience unpleasant withdrawal symptoms. Ask your doctor how to safely stop using.
Researchers have proven the antidepressant effectiveness, favorable tolerability and pharmacokinetic profile of Coaxil in patients with depression, including those with concomitant anxiety; The findings suggest that the drug Coaxil may have additional potential in certain subgroups of depressed patients, such as the elderly and those with chronic alcoholism.
Signs of use
The main symptoms of using Coaxil include the following complications:
- Headache.
- Drowsiness, against the background of constant insomnia.
- Tremor in the limbs.
- Tachycardia.
- Chest pain.
- Nausea and vomiting.
- Dry mouth.
- Labored breathing.
- Pain in the muscles and in the lumbar region.
The longer the period of use, the more clearly all the signs appear. At the stage of deep addiction, rotten teeth and necrotic areas in the mouth and throughout the body are added to the list.
Can antidepressants cause addiction, and what are the side effects of Coaxil?
The antidepressant Coaxil can be mildly addictive, causing both physiological and psychological dependence.
Coaxil can also cause a euphoric effect similar to that of opioids. This influence, combined with consumer tolerance, may lead consumers to take a larger dose than necessary. That is why it should not be taken in doses greater than 100 mg/day.
Side effects resulting from taking Coaxil are largely similar to those of selective serotonin reuptake inhibitors and are minimal compared to tricyclic antidepressants.
The most common side effects are nausea, constipation, abdominal pain, headache, dizziness, and changes in sleep. Anticholinergic effects occur less frequently with tianeptine than with tricyclics. Hepatoxicity is rare. The dosage should be reduced in elderly patients and those suffering from renal failure.
How to get rid of addiction
One of the main problems of coaxial addiction is that it is very difficult to treat. The craving for the drug persists for years; it is difficult to find tranquilizers compatible with them (for example, it is forbidden to take it with monoamine oxidase inhibitors). Treatment is also complicated by the patient’s physical condition - thorombosis, retinopathy and other concomitant diseases.
The Narconon program consistently addresses the above and other problems. Unlike substitution drug courses, designed for several weeks, it is a procedure consisting of stages with multidirectional effects:
- weaning without medication (which is important for psychological dependence) - special assist techniques are used to reduce pain;
- elimination of toxic consequences according to the “New Life” program, including running, sauna, special diet and taking vitamins, oil mixtures, niacin;
- restoration of healthy communication skills, assistance in avoiding a return to the previous lifestyle, developing skills for creative problem solving using the methods of “Objective processes”, “Overcoming ups and downs in life”, “Changing conditions in life”;
- awareness of your obligations, responsibilities and obtaining tools for stopping taking medications in the future - “Personal Values” and “Life Skills”.
During the course of the program, all aspects of addiction are eliminated, the patient is prepared for a new page in life without breakdowns or returns to the past. In most cases the process takes up to 10 weeks. The effect lasts for life.
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Overdose and its treatment
There are several published articles on cases of coaxial poisoning, as well as deaths. Overdose of Coaxil can produce opioid-like effects and lead to respiratory failure and death due to its direct action on the opioid receptor. Additionally, cardiotoxicity may occur as a result of overdose of this drug.
You should take Coaxil exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may change your dose sometimes. Do not take this medication in larger or smaller amounts or for a longer time than recommended.
Health implications
Coaxial addicts' health quickly deteriorates. The person experiences severe headaches, rapid deterioration of vision, and literally before the eyes of the addict, teeth affected by caries turn black. Intoxication of the body worsens overall health. Injection of the drug provokes damage to the walls of blood vessels, thrombosis and purulent lesions of muscles and tissues. This often ends in limb amputation or death.
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** The Drug Directory is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; Before starting to use the drug Coaxil, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace medical advice and cannot serve as a guarantee of the positive effect of the drug.
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** Attention! The information presented in this medication guide is intended for medical professionals and should not be used as a basis for self-medication. The description of the drug Coaxil is provided for informational purposes and is not intended for prescribing treatment without the participation of a doctor. Patients need to consult a specialist!
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special instructions
When discontinuing therapy, it is recommended to reduce the dose gradually over 7-14 days.
It should be used with extreme caution in patients with a history of suicidal tendencies.
When performing a planned surgical operation under general anesthesia, taking Coaxil must be stopped 24-48 hours before it begins. In case of emergency surgery while using the drug, strict medical monitoring of the patient's condition is necessary.
Therapy with tianeptine is possible no earlier than 2 weeks after stopping taking MAO inhibitors. But MAO inhibitors are allowed to be taken 24 hours after stopping tianeptine.
It is recommended to refrain from participating in activities that require rapid psychomotor reactions and increased concentration.
