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Manufacturers: Pharmcenter Vilar
Active ingredients
- Lespedeza bicolor shoots
Disease class
- Chronic renal failure
- Renal failure, unspecified
Clinical and pharmacological group
- Not indicated. See instructions
Pharmacological action
- Diuretic
Pharmacological group
- Diuretics
Description and composition
The medication is a liquid with a characteristic odor, the color of which can vary from light brown with an orange tint to reddish brown. During storage, sediment may form.
As an active ingredient, the drug contains shoots of Lespedeza bicolor.
In addition, the medication contains the following additional substances:
- ethanol;
- anise oil;
- gelatin;
- purified water.
Negative effects
Lespefril is a relatively safe herbal medicine that rarely causes side effects. In some cases, allergic reactions may occur in the form of urticaria, skin rash and redness, itching, and swelling. The drug does not wash out potassium and magnesium, but with systematic use there is a risk of hyponatremia. In such situations, medications, multivitamins and foods containing sodium help compensate for the loss of microelements. In case of overdose, the likelihood of allergies and hyponatremia increases.
Taking Lespefril together with alcohol can enhance the effect of the latter. Ethyl alcohol is also contained in the solution. The component can also enhance the effect of other medications, which is important to consider when using other medications, including sedatives. If it is necessary to include other medications in a complex treatment, it is important to consult a doctor to prevent the development of undesirable effects.
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Indications for use
for adults
Lespeflan is used in combination with other medications for symptomatic treatment as a hypoazotemic and diuretic for chronic renal failure of various origins in the latent, compensated and intermittent period.
for children
The drug is not used in patients under 18 years of age, since it contains ethanol and there is not enough experience in treating minors.
for pregnant women and during lactation
Lespeflan should not be taken by women who are expecting a baby or who are breastfeeding, as the drug contains ethanol, and it can have a negative effect on the fetus and breastfed infant.
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** The Drug Directory is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; Before starting to use Lespeflan, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace medical advice and cannot serve as a guarantee of the positive effect of the drug.
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** Attention! The information presented in this medication guide is intended for medical professionals and should not be used as a basis for self-medication. The description of the drug Lespeflan is provided for informational purposes and is not intended for prescribing treatment without the participation of a doctor. Patients need to consult a specialist!
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Applications and dosages
for adults
The medicine is taken orally; before doing so, it can be diluted with water. Before using the medication, the bottle with it must be shaken.
The treatment regimen is supported by a doctor, individually based on the severity of the clinical picture.
You can take the medicine 5-15 ml (1 teaspoon-1 tablespoon) 3 or 4 times a day for 3-4 weeks. If necessary, the course of therapy can be extended to 6 weeks. After a 2-week break, taking the medication can be repeated.
for children
The drug is not used in children, as it contains ethyl alcohol and there is insufficient experience in treating patients under 18 years of age.
for pregnant women and during lactation
After transferring the baby to breastfeeding during lactation, Lespeflan is prescribed as usual.
Instructions for use
Lespeflan is recommended to be taken orally before meals. The extract can be diluted with ordinary drinking water without flavoring additives. The average daily dosage of the drug is 5-10 milliliters, that is, approximately one full teaspoon or tablespoon. And the maximum daily dose should not exceed 15 milliliters per adult. Lespeflan should be taken at least three times a day.
More frequent use of Lespeflan may lead to the formation of alcohol dependence or its aggravation.
The standard course of treatment rarely exceeds four weeks, but in exceptional cases, doctors prescribe Lespeflan for six weeks.
In this case, it is introduced into the body either intravenously or intramuscularly, which enhances the effectiveness of the course. With long-term use, the dosage of Lespeflan is reduced to 2.5-5 milligrams per dose. This limitation is due to the fact that Lespeflan can lead to a critical lack of sodium in the patient’s body.
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Interaction with other drugs
Due to the ethanol content, it is not recommended to drink the medicine to patients who receive:
- medications that depress the central nervous system;
- hypoglycemic agents such as insulin, metformin, sulfonylurea derivatives;
- medications that provoke intolerance to ethyl alcohol (disulfiram-like reactions, such as nausea, vomiting, palpitations, redness of the skin).
Storage conditions
Lespeflan is produced by several companies, so storage conditions and shelf life of the medication may vary.
Thus, the solution of Dalkhimpharm OJSC Russia can be stored at a temperature of 15-25 degrees for 2 years from the date of production of the medicine.
The drug produced by Pharmcenter Vilar CJSC Russia must be stored in a dark place at a temperature of up to 25 degrees for 4 years from the date of release of the drug.
After the expiration date, Lespeflan cannot be taken; the medication must be disposed of.
It is necessary to ensure that during storage of the drug it cannot be reached by children.
You can buy the medicine without a prescription, but you cannot take it without first consulting a doctor, since only a doctor can make an accurate diagnosis and select an adequate dosage regimen for the drug.
Analogs
In addition to Lespeflan, the following analogues are available for sale:
- Lespefril is a domestic drug that is a complete analogue of Lespeflan. It is produced by ZAO Vifitech, Russia in the form of a solution for oral administration. The medication can be taken by persons over 18 years of age, with the exception of pregnant women and breastfeeding women.
- Lespedeza penny is a dietary supplement produced by. It is sold in herbs weighing 50 g, from which you can prepare infusions and decoctions. The dietary supplement is contraindicated for persons under 18 years of age, pregnant women and breastfeeding women.
- Lespenefril contains lespedeza capitate as an active ingredient. The drug is produced in the form of an alcohol solution, which is contraindicated for persons under 18 years of age, pregnant and lactating women.
- Tincture of Lespedeza kopeck produced in Ukraine, used in the same cases as Lespeflan. It is allowed to be taken only by adults. It is prohibited for pregnant and lactating women.
Taking an analogue instead of Lespeflan is permissible only after consultation with your doctor, since each medication has its own characteristics.
Contraindications for use
Despite its relatively safe composition, the medication has some contraindications, which are important to consider when prescribing treatment. Absolute restrictions include:
- children's age (up to 18 years);
- alcohol dependence (the drug is incompatible with alcohol due to an increase in the level of toxicity in the body and danger to the liver);
- epilepsy;
- pregnancy, breastfeeding;
- traumatic brain injuries;
- liver damage, dysfunction of the hepatic system against the background of progression of various pathologies of the organ;
- hypersensitivity to the main component and other substances in the composition of the drug;
- various types of brain diseases.
The drug should not be taken together with disulfiram, non-selective monoamine oxidase inhibitors. Complex therapy with the use of sulfonamide and metformin is not recommended. The effects of sedative medications can be unpredictable, so treatment using them is also excluded. Also, when used together, it is important to take into account the presence of ethyl alcohol in the composition, which can increase toxicity and side effects.
Particular caution should be exercised in patients suffering from insulin-dependent diabetes mellitus, since Lespefril is not compatible with insulin medications.
It is not recommended to use Lespefril in cases of severe hyponatremia. But the condition can be compensated for with sodium medications.
During the treatment period, care must be taken when driving vehicles and machinery. It is recommended to avoid activities that require increased concentration and quick reactions.
