Indications for use
Therapy and prevention of diseases caused by Klebsiella ozaenae, pneumoniae and rhinoscleromatis as part of multicomponent treatment:
- lesions of the digestive tract ( gastroenterocolitis, pancreatitis, cholecystitis, intestinal dysbiosis );
- ozena, scleroma;
- diseases of young children and newborns of an inflammatory nature ( intestinal dysbiosis, gastroenterocolitis, pemphigus, omphalitis, septicemia, pyoderma, septicopyemia );
- surgical diseases (purulent skin diseases, wound suppuration, peritonitis , burns , pleurisy , osteomyelitis, mastitis, abscess );
- urogenital infections ( pyelonephritis, cystitis, urethritis, vulvitis, colpitis, endometritis, bartholinitis, salpingoophoritis );
- diseases of the ear, nose, throat, pharynx, oral cavity, bronchi, larynx, lungs, pleura of a purulent-inflammatory nature (sore throat , otitis, laryngitis, pharyngitis, periodontitis, stomatitis, frontal sinusitis, sinusitis, pneumonia, bronchitis, pleurisy );
- conjunctivitis of post-traumatic origin, corneal ulcer, keratoconjunctivitis , iridocyclitis ;
- prevention of hospital infections associated with Klebsiella .
Storage conditions
“Klebsiella bacteriophage” instructions recommend storing it under certain conditions that would not negatively affect its medicinal properties. This means that the temperature in the place where the medication is stored should range from two to eight degrees Celsius. It is impossible to overheat or freeze the product, this weakens its properties.
The shelf life of the drug is only twelve months from the moment it was manufactured. If the specified period is exceeded, then the medication will not affect the body properly and its effectiveness will become quite doubtful.
Instructions for use Bacteriophage Klebsiella polyvalent (Method and dosage)
The instructions allow the use of Klebsiella polyvalent bacteriophage internally, in the form of irrigations, applications, enemas, introduction into the nasal cavity, wound, uterus, vagina, sinuses, as well as for drainage of abscesses , bladder, abdominal and pleural cavities, renal pelvis. The drug is taken orally one hour before meals, on an empty stomach.
Recommended dosages for patients over 8 years of age are up to 30 ml of solution when administered orally and up to 50 ml when administered as enemas. Treatment of localized diseases of a purulent-inflammatory nature should be carried out by a combination of local therapy and oral administration of the drug.
When treating ozena or scleroma , the product is used to sanitize the nasal cavity and mucous membranes of the respiratory tract, for administration into the sinuses, and also in the form of inhalations for damage to the larynx, pharynx, and trachea. The dose for treating the mucous membranes of the respiratory tract is 10-20 ml. After sanitizing the mucous membranes, turundas soaked in the product are introduced into the nasal passages one by one and left for one hour. This procedure is repeated up to three times a day for 5-6 weeks. Since ozena and scleroma are chronic diseases, in order to prevent exacerbations, it is recommended to carry out such courses of treatment once a year.
In the treatment of laryngitis, pharyngitis, and sore throats, the drug is used in 15-20 ml doses to sanitize the oropharyngeal cavity three times a day for 9-10 days.
When treating bronchitis and pneumonia , the drug is taken orally up to 20 ml three times a day and is used in the form of inhalations and aerosols. The duration of such therapy is up to 3 weeks.
When treating otitis media, the drug is used to wash and sanitize the ear cavity, 4-5 ml three times a day. The course of therapy lasts 1-2 weeks.
When treating inflammatory diseases of the sinuses, the nose and nasopharynx are washed with 7-10 ml of the drug solution and sinuses are sanitized with 3 ml. This procedure is carried out once a day for 9-10 days. The drug is also administered into the nasal cavity in the form of turundas impregnated with bacteriophage, into each nasal passage in turn and left for 1 hour. This procedure is performed three times a day for two weeks.
When treating chronic periodontitis and stomatitis , rinse the mouth with 15-20 ml of the drug up to 4 times a day, and inject turundas with the drug into the periodontal pockets for 10 minutes. The duration of such treatment usually does not exceed ten days.
For keratoconjunctivitis and conjunctivitis , the product is instilled 3 drops up to five times a day for a week; for purulent iridocyclitis, instill 7 drops up to 8 times a day along with oral administration in standard doses for 10 days; for a purulent ulcer of the cornea, instill 5 drops per day for ten days.
For abscesses , after the cavity has been emptied, the drug is injected into it daily for 10 days.
For pleurisy and peritonitis, the cavity is drained with 20-70 ml of the drug through drainage tubes once a day for two weeks.
For osteomyelitis, the drug is injected into the wound using turundas and drainages, 10-30 ml daily. Treatment is continued for up to three weeks.
When treating suppurative wounds, the agent is used for irrigation, application and is used in the form of bandages; 5-50 ml is injected into the drainage at least once a day for 11-15 days.
In the treatment of gynecological diseases of a purulent-inflammatory nature ( endometritis, suppuration of wounds, vulvitis, colpitis, bartholinitis, salpingo-oophoritis ), the product is used for applications, irrigation, injected into the uterine cavity, wounds, vagina, 10-20 ml once a day for 9-10 days.
For pyelonephritis, cystitis, urethritis, the drug is taken orally in a therapeutic dose up to three times a day on an empty stomach for 2-3 weeks. If the cavity of the renal pelvis or bladder is drained, then the drug is administered through drains 20-40 ml into the bladder or 5-6 ml into the renal pelvis up to three times a day. Therapy is continued for 1-2 weeks.
For pancreatitis, gastoenterocolitis, cholecystitis, and intestinal dysbiosis, Klebsiella bacteriophage is consumed orally in age-specific dosages up to three times a day on an empty stomach for 1-2 weeks. For indomitable vomiting, 20-40 ml of the product is used in the form of high enemas three times a day.
To prevent hospital-acquired surgical infections, the polyvalent Klebsiella bacteriophage is used to treat freshly infected and postoperative wounds, 5-50 ml once daily for a week.
Use of the drug Klebsiella Bacteriophage for infants and children under one year of age
For gastoenterocolitis, sepsis and pneumonia in newborns, the drug is used orally, 3-4 ml 3 times a day, half an hour before feeding. For indomitable vomiting, Bacteriophage is used in 5-8 ml in the form of high enemas once a day. The duration of treatment is 1-2 weeks.
In order to prevent the occurrence of hospital infections in newborns, the drug is used according to epidemic indications orally, 3-5 ml three times a day, half an hour before feeding, throughout the entire stay in the hospital.
When treating pyoderma, omphalitis, and infected wounds, 5-10 ml of solution is used for applications up to 3 times a day for 1-2 weeks.
Release form and composition
The drug is available in the form of a solution for oral, local and external use: a transparent liquid from light yellow to dark yellow, a green tint is allowed (10 ml or 20 ml in glass bottles, 4 or 10 bottles in a cardboard box; 4 bottle in a blister pack, in a cardboard box 1 package and instructions for use of purified polyvalent Klebsiella bacteriophage).
1 bottle contains:
- active ingredient: Klebsiella bacteriophage - a sterile mixture of purified filtrates of phagolysates of the bacteria Klebsiella ozaenae, Klebsiella pneumoniae, Klebsiella rhinoscleromatis;
- excipient: preservative – 8-hydroxyquinoline sulfate monohydrate.
special instructions
Before use, the bottle with the drug must be shaken and its transparency and the presence of sediment assessed. If turbidity or sediment is detected, the drug should not be used!
Due to the presence in the drug of a favorable climate for the development of microorganisms from the environment that cause turbidity of the solution, opening the bottle should be done according to the rules indicated below:
- hands must be washed thoroughly;
- Before removing, the cap must be treated with an alcohol solution;
- the cap should be removed without removing the stopper;
- the drug should be removed from an opened container only by piercing the stopper with a sterile syringe;
- if during opening the cap was accidentally uncorked along with the cap, then it should not be placed with the inner surface on the table, and the bottle should not be left open (after taking the product, it must be closed with the cork);
- The opened bottle should be stored in the refrigerator.
If these rules are followed and there is no turbidity, the product from the opened bottle can be used throughout the entire shelf life.
Mechanism of action
It is the bacterial viruses that have the strongest effect on harmful bacteria that are themselves the main active substance of the drug in question. Their mechanism of action is as follows: the virus detects a cell of a foreign bacterium, which it is able to influence, and in a short time independently becomes a direct part of the cell’s genome, thus influencing the metabolic processes occurring in it and provoking the development of energy starvation. As a consequence of this, the dangerous bacterium dies, while the growth and reproduction of viral cells increases significantly.
It is important to remember that the drug is effective only for the Klebsiella group of bacteria and is absolutely useless for any other pathogens.
A significant advantage is also the fact that during treatment with the drug in question, the development of dysbiosis is impossible, and this contributes to the normal functioning of the gastrointestinal tract.
The concentration of viral cells in the body is high only as long as there is a need to fight the disease. When all harmful bacteria are destroyed, the number of phages is significantly reduced, and the immune system independently gets rid of the remaining ones.
Reviews
Experts consider the main advantages of the described remedy to be the rapid onset of visible results, the absence of any side effects and the possibility of local use of the drug “Klebsiella Bacteriophage”. Reviews from patients confirm not only its effectiveness, but also its absolute safety for those who decide to use it in their treatment.
Everyone knows that the presence of health problems today depends little on the age of the patient. Everyone has the right to receive the highest quality treatment. This is what will become the basis of future physical health. You should not skimp on your own well-being and the well-being of your loved ones. When choosing the best quality product, buy Bacteriophage.
