Instructions for medical use of the drug Okomistin® (Okomistin®)

Okomistin, 0.01%, eye, ear and nasal drops, 10 ml, 1 pc.

The main active ingredient of the drug Okomistin® is the antiseptic benzyldimethyl-myristoylamino-propylammonium, which has a pronounced antimicrobial effect against gram-positive and gram-negative, aerobic and anaerobic bacteria in the form of monocultures and microbial associations, including hospital strains with multidrug resistance to antibiotics. The drug acts on chlamydia, pathogenic fungi, as well as herpes viruses and adenoviruses. The drug is more effective against gram-positive bacteria, including: staphylococci, streptococci. It has an antifungal effect on ascomycetes of the genus Aspergillus and the genus Penicillium, yeasts (Rhodotorula tubra, Torulopsis glabrata) and yeasts (Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, T. schoenleini, T. violaceum, Epidermophyton Kaufman-Wolf, E, floccosum, Microsporum gypseum , Microsporum canis), as well as other pathogenic fungi (for example, Pityrosporum orbiculare (Malassezia furfur)) in the form of monocultures and microbial associations, including fungal microflora with resistance to chemotherapeutic drugs. The action of benzyldimethyl-myristoylamino-propylammonium is based on the direct hydrophobic interaction of the molecule with the lipids of the membranes of microorganisms, leading to

to their fragmentation and destruction. In this case, part of the benzyldimethylmyristoylaminopropylammonium molecule, plunging into the hydrophobic portion of the membrane, destroys

the supramembrane layer loosens the membrane, increases its permeability to large molecular substances, changes the enzymatic activity of the microbial cell, inhibits enzyme systems, which leads to inhibition of the vital activity of microorganisms and their cytolysis. Benzyldimethyl-myristoylamino-propylammonium has a high selectivity of action against microorganisms, because has virtually no effect on the membranes of human cells, which is due to the different structure of the latter - the significantly longer length of lipid radicals, which sharply limits the possibility of hydrophobic interaction of benzyldimethyl-myristoylamino-propylammonium with cells.

Under the influence of the drug, the resistance of bacteria and fungi to antibiotics is reduced. Benzyldimethyl-myristoylamino-propylammonium has anti-inflammatory and immunoadjuvant effects, enhances local protective reactions, regenerative processes, activates nonspecific defense mechanisms due to modulation of the cellular and local humoral immune response.

Indications for use of the drug Okomistin

Ophthalmology Okomistin®, eye drops, ear drops, nasal drops are recommended for use in the complex treatment of infectious processes in the anterior part of the eye (blepharitis, conjunctivitis, keratitis, keratouveitis), eye injuries, eye burns (thermal and chemical); in the preoperative and postoperative periods for the treatment and prevention of purulent-inflammatory eye lesions. Prevention of ophthalmia of newborns, including gonococcal and chlamydial.

Otorhinolaryngology The drug is used in the complex treatment of acute sinusitis/rhinosinusitis, exacerbation of chronic sinusitis/rhinosinusitis, acute rhinitis; acute and chronic external otitis, chronic purulent mesotympanitis, otomycosis.

Contraindications and unwanted effects

The main contraindication to the use of Okomistin is individual intolerance. Rarely, when using drops, hypersensitivity reactions develop, accompanied by severe pain, burning and discomfort in the eyes. In this case, stop treatment and contact your doctor to select another antimicrobial agent.

Usually, putting drops into the eyes does not cause any negative sensations.

Rarely do patients report mild discomfort that goes away on its own after 15-20 minutes.

Reviews

Nina, 22 years old:

“I am familiar with conjunctivitis firsthand - I get sick with this infection several times a year. Over time, I developed the most effective, in my opinion, treatment tactics, and if previously I had several bottles of antibiotics, artificial tears and vasoconstrictor drops on my shelf, now one bottle of Okomistin is enough for me. This drug is easy to use, versatile, quickly relieves itching and discharge from the eyes, and has an attractive price.”

Okomistin is a quick relief for eye inflammation.

Alena (daughter Christina, 8 months):

“I first encountered Okomistin drops almost immediately after being discharged from the hospital. A week after birth, my daughter’s eye began to turn sour, and every day the situation became worse. The pediatrician, who came to our home for a patronage examination, advised me to wash Christina’s eyes with tea leaves more often and buy Okomistin drops.

Although the instructions indicate that the medicine is contraindicated for children under 18 years of age, the doctor reassured me that it is safe to use even for newborns. I instilled 1 drop into both eyes of my daughter three times a day. Christina was not capricious and endured the procedure absolutely calmly. After 3-4 days, the discharge stopped, and the eye no longer festered.

A little later, I found good reviews on the Internet about the use of these antiseptic drops for a runny nose or otitis in children. Therefore, I think that the medicine will remain in our home medicine cabinet for a long time.”

Ignatenkov V.B., ophthalmologist:

“Okomistin is a relatively new drug, known only in the post-Soviet countries. While it receives the necessary documentation and undergoes clinical trials, the instructions indicate that its use during pregnancy, lactation or childhood is contraindicated. In fact, many doctors, including myself, prescribe it for infectious eye lesions, even for infants.

I like that these drops quickly clear up the infection, do not cause side effects and are well tolerated by my patients.”

When is Okomistin prescribed?

Okomistin eye drops are used for independent or complex therapy:

• acute/chronic conjunctivitis - inflammation of the outer membrane of the eye;
• blepharoconjunctivitis - inflammation of the conjunctiva, combined with damage to the eyelids;
• keratitis - an infectious process in the cornea;
• uveitis - inflammation of the choroid of the eye;
• injuries to the organs of vision.

Medicine is often prescribed to prevent complications - instillation begins 2-3 days before the upcoming eye surgery.

Analogues of Okomistin

Level 4 ATX code matches:
Dancil

Oftadek

Signitsef

Oftaquix

Vitabact

Tsiprolet

Perhaps the main analogue of Okomistin can be considered Miramistin . This medicine is also available in the form of eye drops. In addition, thanks to the active medicinal component, this drug has a similar effect to Okomistin in the treatment of ophthalmic diseases that develop under the influence of gram-positive bacteria , as well as the herpes virus and other harmful organisms.

Release form

Okomistin®, eye, ear, nasal drops, 1 ml or 1.5 ml in disposable polymer

dropper tube, 5 or 10 ml in polymer bottles, sealed with a dropper stopper and a screw-on cap with first opening control; 20 ml in glass

bottles sealed with a rubber stopper and an aluminum or polyethylene cap

dropper cap.

1 or 5 bottles or 5 or 10 dropper tubes with instructions for use per pack

from cardboard.

Special instructions for the use of the drug Okomistin

Contact lenses should be removed immediately before instillation of Okomistin® and put on no earlier than 15 minutes after instillation. To avoid contamination and cross-infection, do not use the same vial to treat eye, nose, and/or ear infections at the same time. To prevent contamination of the drug solution during instillation, patients should avoid contact of the dropper tip with the eye and skin. Sharing the dropper bottle by more than one person may spread the infection.

Use during pregnancy and lactation. The use of the drug during pregnancy and lactation is possible only if the expected benefit to the mother outweighs the potential risk to the fetus and child. Children . The drug can be used in pediatric practice. The ability to influence the reaction rate when driving vehicles or other mechanisms. After using the drug, a temporary decrease in the clarity of visual perception is possible and until it is restored, it is not recommended to drive a car or engage in activities that require increased attention and reaction.

Use of the drug Okomistin

Ophthalmology . Locally. For adults, for therapeutic purposes, the drug Okomistin® is instilled into the conjunctival sac, 1-2 drops 4-6 times a day until clinical recovery. For prophylactic purposes, the drug is instilled 2-3 days before surgery, as well as for 10-15 days after surgery, 1-2 drops 3 times a day. When treating eye burns, after washing the eye with plenty of water, perform frequent instillations (every 5-10 minutes) for 1-2 hours. For further treatment, the drug is used 1-2 drops 4-6 times a day. In pediatric practice, for the treatment of bacterial conjunctivitis in children, the drug Okomistin® is instilled into the conjunctival sac, 1 drop up to 6 times a day for 7-10 days. To prevent ophthalmia in newborns, immediately after birth, the child is instilled with 1 drop of the drug into each eye 2 times with an interval of 2-3 minutes. Otolaryngology. Locally. For adults with acute sinusitis/rhinosinusitis, exacerbation of chronic sinusitis/rhinosinusitis, acute rhinitis, infection of the nasal mucosa, Okomistin® is instilled 2-3 drops into each nostril, 4-6 times a day. The course of treatment is up to 14 days. In pediatric practice, for the treatment of acute rhinosinusitis, exacerbation of chronic rhinosinusitis in children over 1 year of age, the drug Okomistin® is instilled into each nasal passage, 1-2 drops up to 4-6 times a day for 10-14 days. For adults. Locally. For acute and chronic external otitis, otomycosis, the drug Okomistin® is instilled into the external auditory canal 5 drops 4 times a day or, instead of instillation, a gauze turunda soaked in the drug is injected into the external auditory canal 4 times a day. The course of treatment is 10 days. In adults with chronic mesotympanitis, it is used in complex treatment using hardware ultrasonic irrigation or injection into the tympanic cavity together with antibiotics. In the absence of positive dynamics (increased severity or appearance of new signs/symptoms of the disease, the occurrence of complications) on the 3-4th day of therapy using the drug Okomistin®, you must consult a doctor!

Okomistin price

This drug can be purchased at all pharmacies. There is only one manufacturer - Infamed (Russian Federation). Approximate prices in Moscow: