Belgian vaccine Priorix: composition, instructions for use and price

Priorix is ​​an imported vaccine against measles, rubella and mumps. Manufacturer: GlaxoSmithKline Biologicals sa, Belgium. The vaccine is proven to be highly effective: antibodies against measles are detected in 98% of those vaccinated, against rubella in 99% and against mumps in 96%. Priorix fully complies with WHO requirements for the production of biological products.

Why vaccinate your child against measles?

Measles is one of the most dangerous “childhood” diseases. Firstly, it is extremely contagious: the chances of getting sick after contact with someone with measles are close to 100%. A decrease in the percentage of vaccinated children, even by a small amount, immediately results in a surge in the incidence of measles. Already in the 2000s, epidemics were recorded in such prosperous countries as Ireland and the USA: the reasons were the availability of air travel and refusals to vaccinate. Secondly, measles has a high mortality rate (although not as high as tetanus and diphtheria), and children under 5 years of age are especially susceptible to it. Measles still has no specific treatment – ​​only symptomatic treatment. In addition, it causes severe complications on the respiratory system, including bronchitis and pneumonia, and can also lead to partial loss of hearing or vision in the child.

Price at the pharmacy, expiration date and storage conditions

You can purchase Priorix for vaccination in pharmacies across the country. The cost of the drug varies from 300 to 330 rubles.
The medicine is dispensed with a prescription from a doctor. When purchasing a vaccination, you should pay attention to the expiration date. The Belgian vaccine must be used within two years from the date of its release.

Shelf life largely depends on storage conditions. If the temperature regime and optimal humidity level are violated, Priorix can quickly deteriorate.

The bottle with lyophilisate should be stored in the refrigerator, where the temperature is within +2-8 degrees. A syringe with a solvent can be kept in a room where the thermometer shows from +2 to +25. Freezing Priorix is ​​prohibited.

Why vaccinate your child against rubella?

It is known that rubella is most dangerous for pregnant women, since it has an extremely negative effect on the fetus: more than half of newborns experience deafness, and blindness and heart disease are also common. Therefore, the advisability of rubella vaccination for women planning pregnancy seems to be beyond doubt. However, parents often ask the question: why vaccinate a one-year-old girl or, especially, a boy against rubella? After all, it is known that in most cases rubella is quite mild?

As in the case of mumps, the most well-known complication among the people is far from the only one and, alas, not even the most terrible. Progressive rubella panencephalitis, a rare but terrible complication, most often affects boys aged 8 to 19 years. With this complication, a person’s intellect gradually fades and motor functions die off, and it ends with dementia and death. Other complications from rubella that do not discriminate by gender include arthritis, pneumonia and hepatitis.

Drug interactions

Priorix can be administered on the same day with the following vaccines: ADS, DTP, against Haemophilus influenzae type b, against hepatitis B, live and inactivated polio vaccine. An important condition is to administer drugs to different parts of the body with different syringes.

Any other live viral vaccine can be administered at a minimum interval of 1 month.

Priorix cannot be mixed in the same syringe with other vaccines.

This product may be used for booster vaccination in individuals who have previously been vaccinated with monovalent mumps, rubella, and measles vaccine or another appropriate combination vaccine.

If it is necessary to carry out a tuberculin test, it should be performed either simultaneously with vaccination or 6 weeks after it, since the measles vaccine process (and possibly mumps) can cause a temporary decrease in skin sensitivity, which is why it is possible to obtain a false negative result of the tuberculin test.

Why vaccinate your child against mumps?

Mumps (mumps) is not a deadly disease, but can lead to extremely unfavorable complications. It gained fame due to the fact that it is a fairly common cause of infertility in men, which develops as a result of orchitis - inflammation of the testicles. The fact is that the mumps virus affects glandular tissue and is not limited to the postauricular salivary glands (although they are, indeed, usually affected first), but can develop in the tissues of the thyroid gland, pancreas, testicles in boys or ovaries in girls.

Two of the most common myths about the vaccine against it are associated with this feature of mumps. First: the vaccine causes infertility in boys. Of course, this is not true. When grafting, testicular tissue is not affected. Second: there is no point in vaccinating boys before puberty. And this is not so - infertility is caused not by low-quality sperm, but by atrophy of testicular tissue, which, unfortunately, does not depend on age. And high-quality immunity is formed after revaccination, and you may simply not have time to vaccinate your child before he gets sick.

The second question, no less frequent: if mumps is dangerous only for boys, why vaccinate girls? Just for the sake of the notorious population immunity? Of course not. The fact is that, in addition to orchitis, partotitis can cause pancreatitis, and this is lifelong, because the pancreas tissue is not restored; as well as encephalitis and meningoencephalitis - the most dangerous types of brain inflammation. Not very often, but it still happens that the experience of mumps ends in deafness.

What does it contain?

Priorix contains viral strains of pathogens of dangerous diseases. They promote the production of antibodies. The composition also contains additional components.

The main elements of Priorix:

• attenuated measles virus strain Schwarz;
• weakened mumps pathogen strain Jeryl Lynn;
• attenuated rubella virus variant strain Wistar RA 27/3.

Among the excipients in the Belgian vaccine there are:

• amino acids;
• sorbitol;
• lactose;
• mannitol;
• distilled water.

The preparation does not contain merthiolate, antibiotics, aluminum salts or other harmful substances.

Possible side effects of Priorix

The specificity of the vaccine against measles, rubella and mumps is that it gives two waves of reaction: the first - within 24 hours after vaccination and the second - approximately 9-10 days after it. The child's condition should be carefully monitored during these periods of time.

In 60% of cases, Priorix vaccination is tolerated by the child without any consequences.

In the remaining cases, the most common occurrence is a rise in temperature, which accompanies the body's production of protective antibodies. Runny nose, cough, hives, pain and swelling at the injection site are also common.

Less common consequences of vaccination are upper respiratory tract infections, otitis media, bronchitis, nervousness, insomnia, conjunctivitis, febrile convulsions.

If any symptoms last longer than two days, you should consult a doctor.

Analogs

It is not difficult to find an analogue for the Priorix vaccine. Anti-measles, anti-rubella and anti-mumps drugs are produced by domestic and foreign manufacturers. Here are some of them:

• “Live cultural measles vaccine” – Russia;
• “Vaccine against cultural rubella live” – Russia;
• “Mumps cultural live vaccine” – Russia;
• Measles vaccine "Ruvax" - France;
• Rubella vaccine "Ervevax" - Belgium;
• Rubella vaccine "Rudivax" - France.

The advantage of Priorix is ​​that you can give an injection for three different diseases at the same time. It is possible to vaccinate those who were not vaccinated in childhood.

How to prepare for the Priorix vaccination

To properly prepare for vaccination, you should protect your child from possible consequences. Firstly, for several days before and after vaccination you should not visit crowded places or contact people who are known to be sick (if you have to, reschedule the vaccination). Secondly, carefully monitor possible manifestations of ARVI in the child: he must be completely healthy. You should also not vaccinate if your child is actively teething.

It is necessary to eat light, healthy foods, do not overindulge in sweets and allergens, and drink more clean water. You should not introduce new complementary foods on the day of vaccination.

The child’s room, or better yet the entire apartment, should be well ventilated. The indoor humidity level should be maintained at least 65%.

You can give your child an antihistamine, such as Zyrtec, for several days before and after the vaccination.

Indications and contraindications

According to the instructions, you need to get vaccinated:

• children aged 1 year;
• children over one year old who miss the first vaccination;
• children as part of routine revaccination at the age of six years;
• patients over six years of age - if they miss a scheduled revaccination due at the age of six;
• children over six years old who have not previously been vaccinated against measles, rubella, mumps - receive two vaccinations with a minimum interval of one month;
• children whose parents do not remember whether the baby was vaccinated, and there is no documentary evidence of this fact;
• when traveling abroad - for children under one year old;
• in countries with a high risk of disease, the vaccine is given at six or nine months;
• adult patients who have not had measles, rubella, mumps, and have not been vaccinated against them.

In accordance with the national vaccination calendar, the measles-rubella-mumps vaccination is carried out according to the schedule:

• 12 months;
• 6 years.

These two doses of the vaccine ensure the formation of stable specific immunity to all three infections.

The manufacturer's instructions also recommend exactly this vaccination regimen against the above diseases.

Immunization against measles, rubella and mumps is recommended for healthcare workers, military personnel and women planning to conceive (no later than 3 months before the expected pregnancy).

Contraindications are:

• any acute conditions, including exacerbation of chronic pathologies;
• allergies that appeared during the previous administration of the drug;
• HIV status and other immunodeficiency conditions;
• intolerance or allergy to one of the components of the drug;
• pregnancy.

The vaccine should be administered with caution to those who suffer from allergic reactions. The most common allergen is chicken egg white. You can get vaccinated with medication support - you need to take antihistamines a few days before the appointed date. After the injection, patients must remain for some time under the supervision of medical staff in the vaccination room, which is equipped with the necessary arsenal of anti-shock and anticonvulsant drugs.

Use during pregnancy and breastfeeding

During pregnancy, vaccination is strictly prohibited. This is one of the main contraindications.

During lactation, it is necessary to compare the possible harm and benefits of using the drug.

Women of childbearing age are vaccinated subject to three months of protection against pregnancy.

Literature

• Clayton E.W., Rusch E., Ford A., Stratton K.
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• Offit PA
  Vaccinated: One Man's Quest to Defeat the World's Deadliest Diseases. - HarperCollins, 2009. - 272 p. — ISBN 9780061871511.

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special instructions

A history of contact dermatitis neomycin , as well as an allergic reaction to chicken eggs, excluding anaphylactic reaction , are not a contraindication to vaccination .

The vaccine can be administered to patients with asymptomatic HIV infection and AIDS .

For acute intestinal and other diseases, as well as mild acute respiratory viral infections