Angiovitis. Instructions for use, composition of vitamins. Price, analogues

Most often, people consider vitamins as an optional element in their daily diet. Many people regard drugs of this kind as a useful supplement in the autumn-spring period, so as not to get sick and maintain immunity. They are not particularly perceived as medicines. At the same time, there are situations when some diseases have a very strong effect on the body suffering from a deficiency of nutrients. This is especially true for pathologies associated with the functioning of blood vessels and a lack of vitamins B9, B6 and B12. In this case, vitamins are converted into medicines, in particular, this applies to the “Angiovit” vitamins.

Chemical composition

The active components of the drug are B vitamins:

Dextrose, potato starch, talc, and calcium stearate are used as excipients.

"Angiovit": reviews

There are practically no negative reviews regarding the drug "Angiovit", with the exception of stories about the combination of a vitamin complex with incompatible drugs.

In most cases, a course of taking the drug allows you to get rid of the deficiency of B vitamins in the body. This affects overall health and helps alleviate diseases caused by deficiency.

The vitamin complex "Angiovit", despite the small number of elements included in its composition, improves the patient's well-being and alleviates the symptoms of existing diseases.

Release form

Angiovit is a two-layer white tablet that has convex shapes on both sides. Each tablet is coated with a sweet coating.

The vitamin complex is packaged in contour packaging with separate cells. One blister contains 10 tablets.

Angiovit is produced in a cardboard box containing 6 blisters. There are manufacturing companies that produce vitamin complexes in polymer jar packaging with a screw cap.

pharmachologic effect

Angiovitis belongs to the category of combined drugs.

It contains a complex of B-group vitamins, which are a stimulator and supporting factor for the synthesis of homocysteine ​​into methionine. The last substance is an essential amino acid belonging to the group of sulfur-containing acids.

The multivitamin complex Angiovit helps stimulate methionine metabolism , reducing the concentration of hemocysteine ​​in human blood. This effect is achieved through the redistribution of methylene and sulfate groups in the homocysteine ​​- methionine or homocysteine ​​- cysteine ​​chain.

Reactions proceed along these chains due to the activation of the enzymes mythionine synthase and cystathionine synthase. Homocysteine ​​is a protein-free low molecular weight compound that, when accumulated in the blood, can have a toxic effect.

A high content of homocysteine ​​(a protein-free low-molecular compound) in the body leads to the development of cardiovascular diseases, for example, atherosclerosis

A high content of homocysteine ​​in the body leads to the development of diseases of the blood vessels, heart, and brain, such as:

• atherosclerosis;
• heart attack;
• stroke;
• thrombosis;
• fragility of blood vessels due to diabetes mellitus.

Also a multivitamin:

• helps with constant miscarriages;
• eliminates the development of pathologies and mutations in the fetus;
• maintains the necessary level of vitamins in the blood;
• prevents the development of anemia.

Angiovit is recommended to be taken for autism
Angiovit is prescribed to reduce the level of toxic amino acids in the following diseases:

• Parkinson's and Alzheimer's disease;
• autism;
• depression;
• senile dementia;
• infantile central palsy.

Pharmacological properties are due to additional properties of the components of the product:

• folic acid is involved in the metabolism of vital elements;
• pyridoxine hydrochloride normalizes hemoglobin production and reduces cholesterol concentration;
• Cyanocobalamin is involved in hematopoiesis and restores the functioning of the nervous system.

Vitamins Angiovit

The drug is a multivitamin complex that contains three active ingredients. The medication is used to prevent hypovitaminosis and as one of the components of a treatment complex for the following lesions of the cardiovascular and nervous systems: ischemic infarction, arrhythmias, atherosclerosis, etc.

Composition and release form

The pharmacological drug Angiovit is available in the form of white, milky or pale yellow tablets, enteric-coated. The tablets are placed in an aluminum or plastic blister of 10 pieces, in a cardboard package with instructions for use. Before starting to use this multivitamin complex, it is recommended to consult a specialist.

pharmachologic effect

Angiovit is a combination drug that contains vitamins B6, B9 and B12. The drug helps activate and accelerate metabolic processes. In addition, the components included in Angiovit reduce the concentration of the substance homocysteine, which is one of the most important causes of the development of vascular diseases, arterial thrombosis, ischemic stroke, and heart attacks. The development of hyperhomocysteinemia is provoked by a lack of pyridoxine, vitamin B12 and folic acid in the body.

The drug is widely used for the treatment and prevention of not only cardiovascular diseases, but also problems with cerebral circulation (sclerotic changes in blood vessels, strokes), degenerative changes in the tissues of the central nervous system, and regulation of blood clotting. The vitamin complex helps maintain the immune system.

Pharmacodynamics and pharmacokinetics

The drug Angiovit activates the metabolic processes of methionine metabolism with the help of a complex of B vitamins, normalizes the content of homocysteine ​​in the blood plasma, prevents the progression of vascular diseases, thrombus formation, and in combination with aminoglycosides facilitates the course of coronary heart and brain disease.

Folic acid is directly involved in the synthesis of amino acids, DNA, RNA of body cells, and regulates the course of erythropoiesis processes. In addition, the substance minimizes the risk of spontaneous abortion in the early stages of gestation. Cyanocobalamin (vitamin B12) is one of the most important elements of many metabolic processes and is responsible for the production of alpha amino acids and myelin, which is part of the nerve. This substance improves the resistance of red blood cells to hemolysis (destruction) and stimulates the regeneration of myocardial tissue.

Pyridoxine, its active form pyridoxal phosphate, is essential for the normal functioning of the central and peripheral nervous systems. In cases of toxicosis in pregnant women, this substance prevents the development of weakness, fainting, nausea and vomiting by blocking vomiting receptors. Vitamins B12 and B6 are important components of the metabolic processes of the substance homocysteine; they activate many enzymes in the body that are necessary for many biochemical reactions.

Folic acid is rapidly absorbed in the small intestine, its maximum concentration in plasma is reached after 30-60 minutes. The absorption of vitamin B12 occurs after its reaction in the stomach with the “internal Castle factor” - a glycoprotein that is produced by parietal cells. The maximum concentration of this substance is reached 6-12 hours after administration.

Both of these components are characterized by binding to blood proteins by 80% and destruction of their excess by liver cells. The average half-life is approximately 6 days. A small part is excreted in urine and bile during the first 8 hours after administration. About 25% of metabolites are excreted in feces. The components of the drug penetrate the placental, blood-brain barrier and into breast milk.

Indications for use of Angiovit

The drug Angiovit is prescribed for the complex treatment of patients who suffer from cerebral circulatory insufficiency due to atherosclerosis, hyperhomocysteinemia and coronary heart disease. The vitamin complex is used by patients with diabetic angiopathy, Alzheimer's disease, dementia and post-stroke conditions simultaneously with other medications.

Angiovit is indicated for severe hypovitaminosis during pregnancy as a source of folic acid, which is necessary for a normal intrauterine fetus and the prevention of miscarriage in the early stages. Many women note a decrease in the manifestations of signs of toxicosis (nausea, vomiting, dizziness, loss of appetite, etc.) with constant use of Angiovit.

Pharmacodynamics and pharmacokinetics

Multivitamins Angiovit normalize methionine synthesis, activating the production of enzymes. At the same time, the homocysteine ​​content decreases, the patient’s condition with atherosclerosis, ischemic diseases or thrombosis is stabilized.

Pyridoxine hydrochloride stimulates brain function , improving the absorption of glucosides by brain cells and amino acid metabolism. It is involved in the synthesis of neurotransmitters in the central nervous system.

Vitamin B12 contains cyano and cobalt groups, it contributes to:

• increased blood flow due to blood thinning;
• accelerating the process of hematopoiesis;
• normalization of the process of cell growth and division;
• maintaining the integrity of the electrically insulating sheaths of nerve fibers, which helps maintain uninterrupted transmission of impulses from the brain;
• lowering cholesterol levels and resolving small cholesterol plaques.

Folic acid activates the production of red blood cells, which transport oxygen to tissues. It helps eliminate the symptoms of hypoxia. The acid also prevents the growth of malignant tumors, participates in the formation of the DNA chain and maintaining its integrity.

Angiovit is completely absorbed into the blood within 5-10 minutes. after reception. Pyridoxine is activated by liver enzymes and excreted by the kidneys. Cyanocobalamin is absorbed in the stomach and transported to the tissues by a glycoprotein.

Pharmacokinetics

Folic acid, which is part of the composition of this medication, is absorbed into the small intestine at a very high speed. Since the last dose, folic acid levels reach their maximum approximately 30-60 minutes later.

Angiovit tablets

Vitamin B12 begins to be absorbed after its interaction with a glycoprotein produced by the parietal cells of the stomach.

The maximum level of concentration of the substance in the blood plasma is achieved after 8-12 hours from the moment of the last dose of the drug Angiovit. The action of vitamin B12 is very similar to folic acid because it undergoes enterohepatic recirculation.

Why is Angiovit prescribed?

The complex is used for diseases of the heart and blood vessels caused by increased concentrations of homocysteine ​​in the body:

• thrombosis of large veins;
• damage to heart vessels during a heart attack;
• coronary insufficiency;
• combination of atherosclerosis and thrombosis;
• ischemic or myocardial stroke;
• cerebral circulatory disorders due to multiple sclerosis;
• angina pectoris;
• fragility of blood vessels due to diabetes.

Angiovitis is prescribed for cardiovascular diseases, for example, for vein thrombosis.
The complex drug is prescribed to men in preparation for conception. It helps:

• increase sperm motility;
• reduce vascular permeability;
• increase the number of sperm produced with a healthy set of chromosomes.

Angiovit (for which the drug is prescribed during pregnancy will be described below) is additionally taken during the gestation period when blood exchange between the mother and child is disrupted and to prevent the development of iron deficiency.

The drug "Angiovit"

Not long ago, deficiency of vitamins B9, B6 and B12 in the human body was treated with syringes with ampoules and very painful injections. If we talk about what the drug “Angiovit” represents, it is best to say that it is a painless solution to the problem of hypovitaminosis of elements from group B, along with pyridoxine, cyanocobalamin and folic acid.

All these elements affect the condition of blood vessels in the human body. While taking the drug, the microcirculation of substances in their walls, including capillaries, is restored, strengthened and become much more resistant to external influences and damage, helping to reduce the risk of blood clots.

According to reviews, “Angiovit” reduces the content of a substance called homocysteine ​​in the blood. Its excessive amount in the body can lead to various pathologies of the heart or blood vessels, including myocardial infarction and stroke.

Contraindications

The multivitamin complex should not be taken:

• in the presence of hypersensitivity to its individual components;
• together with blood thickening drugs;
• with insufficient production of glycoprotein in the stomach;
• children under 12 years old;
• for various diseases of the digestive system, accompanied by inflammation or in the acute stage;

It is strictly forbidden to take Angiovitis simultaneously with alcohol-containing foods and drinks.

This is due to the fact that ethyl alcohol reduces the therapeutic effect of the drug due to the breakdown of vitamins and their insufficient transport to tissues. It is allowed to consume ethanol 4 hours after taking it or 9 hours before the planned use of Angiovit.

Side effects

The drug has virtually no side effects, as it is well tolerated by the body.

But if allergic reactions or hypervitaminosis occur, the following may occur:

• swelling of the throat or tongue;
• hives;
• itching sensation and redness of the skin;
• insomnia;
• migraine;
• lacrimation;
• dizziness or blurred vision.

One of the possible adverse reactions when taking angiovit is nausea and vomiting.
Quite rarely, adverse reactions are possible in the form of:

• feelings of nausea;
• pain in the stomach;
• severe belching;
• increased gas formation in the intestines;
• vomiting with mucus.

If any symptoms occur, you should contact your physician. If an allergic reaction to the components of the drug is confirmed, symptomatic treatment is carried out or the drug is stopped.

In case of an acute individual reaction to synthetic B-group vitamins, symptoms may appear that require immediate medical intervention:

Instructions for use of Angiovit and dosage

Angiovitis is taken orally, without chewing and with a small amount of liquid. Since the tablet has a protective shell, damage to it when biting can cause early disintegration of the components and lack of therapeutic effect.

The vitamin complex is taken 1 time per day, just 1 tablet. To achieve the best therapeutic effect, the tablet is taken in the morning.

The duration of the course should be determined by the therapist depending on the degree and type of disease. On average, Angiovitis is prescribed as a monthly course. If necessary, only the therapist can extend it, maintaining the required interval between the last and new appointments.

According to the instructions, angiovit is allowed to take 2 tablets for 5 days

If the concentration of homocysteine ​​in the blood is critical, it is possible to take 2 tablets of multivitamins in the first 5 days, but this situation must be monitored around the clock by a therapist and cardiologist.

Overdose

Angiovitis (for which the vitamin complex is prescribed is described in the instructions) can cause hypervitaminosis, in which the following are observed:

• dizziness;
• vomit;
• nausea;
• blockage of capillaries;
• anaphylactic shock;
• convulsions;
• impaired motor ability of the limbs;
• loss of skin sensitivity.

Before taking any multivitamins, incl.
angiovitis, discuss this issue with your doctor. It must be remembered that the use of any vitamin-containing medications must be agreed with the therapist after a thorough study of the medical history and receipt of test results. Self-administration of Angiovit can lead to the development of side effects and their development into more serious complications.

special instructions

Angiovitis should not be prescribed simultaneously with drugs that increase blood clotting.

During treatment, it should be taken into account that folic acid reduces the effectiveness of phenytoin, and its effect is negatively affected by methotrexate, triamterene, and pyrimethamine.

During pregnancy and breastfeeding, the vitamin complex is prescribed only after medical advice.

Impact on the ability to drive vehicles and complex mechanisms

Taking Angiovit does not negatively affect the ability to drive vehicles or perform potentially hazardous types of work.

Interaction

The multivitamin complex has a complex composition and highly reactive components.

Therefore, there are medications and substances that cannot be combined with Angiovitis:

Storage conditions

Angiovit (the therapist will also tell you why the complex is prescribed) must be kept before and after opening the package in a dry place , out of direct sunlight at room temperature.

The product should be inaccessible to children or animals, as it can cause poisoning.

Angiovitis during pregnancy

Pregnancy is not included in the list of contraindications for taking Angiovit. The drug is successfully used to relieve hypovitaminosis during pregnancy.

A multivitamin can reduce the risk of the fetus developing:

• heart defects and diseases of the vascular system;
• dementia or autism;
• immunodeficiency.

The drug is also used when there is insufficient exchange of blood, nutrients and oxygen through the placenta.

Angiovitis is recommended to be taken as a course during pregnancy planning , as it promotes the proper formation of germ layers and cell division. But the vitamin complex must be taken during pregnancy only as prescribed by a gynecologist. The doctor will determine the duration of the course and calculate the required amount of the drug.

When taking a medication on your own, hypervitaminosis in pregnant women may occur, which can manifest itself:

• kidney failure or pain;
• the appearance of an allergic cough;
• urolithiasis;
• angina pectoris, tachycardia or arrhythmia.

If there is an excess amount of B vitamins during pregnancy, symptoms may appear:

It is worth noting that excessive consumption of synthetic fortified drugs increases the risk of having a child with a tendency to allergic reactions and weak immunity.

If symptoms of hypervitaminosis are detected, you should stop taking the drug and immediately consult a gynecologist. He will select a sufficiently balanced diet to relieve allergy symptoms and obtain sufficient amounts of all necessary microelements.

Use during pregnancy

The drug is approved for use during pregnancy and is quite often prescribed for disorders of fetoplacental metabolism, which is a condition in which the fetus is not able to receive enough nutrients and acids in the volume required for it.

The drug is not able to have any negative effects on the formation and development of the fetus, for this reason it can be used even in the early stages of pregnancy.

However, before taking this medicine, you must obtain a doctor’s opinion on your health status, as well as find out the required dosage for use.

Price of Angiovit in pharmacies in Moscow, St. Petersburg, regions

The price of Angiovit multivitamins varies from 100 to 300 rubles. It depends not only on the region and the pricing policy of the pharmacy, but also on the manufacturer.

Analogs

The multivitamin complex has no analogues similar in structure. There are similar drugs, but only in pharmacological properties.

Angiovit (for which multivitamins are prescribed is described in the instructions) has several advantages:

• it has a reasonable price;
• the effect of use is felt almost immediately, since the drug has a uniquely selected composition.

Similar medicines include:

• Aerovit.

Vitamins are available in the form of tablets for oral use. They are taken in a monthly course of 1 tablet in the morning.

• Alvitil.

The drug is produced in 2 forms: syrup and tablets. Both types are intended for oral administration.

Daily dosage of Alvitil:

• adults: 2 tsp. liquid complex or 2 tablets;
• Children under 6 years of age are recommended to give no more than 1 tsp. syrup;
• children over 6 years old are given 1 tsp. liquid substance or 2 tablets.

The duration of taking the vitamin complex is determined by the pediatrician.

• Foliber.

The drug is taken 1 tablet per day orally with water. The course of treatment must be at least 30 days.

• Undevit.

The drug can only be taken when patients reach 14 years of age. The daily dose of the drug is no more than 3 tablets. To prevent deficiency of essential substances, Undevit is taken for a course of 30 days, 1 tablet per day.

• Sana-Sol.

The multivitamin complex can be given to children from 1 to 3 years old in the amount of 1 tsp. For older children and adults, you can take 2 tsp per day. facilities. The bottle must be shaken well before dosing. The duration of treatment should not exceed 30 days.

• Hexavit.

The medication is prescribed after meals:

• children 3-7 years old, 1 tablet twice a day;
• adults and children over 7 years old, 1 tablet three times a day.

The course course should not exceed 30 days.

• Pentovit.

Vitamins must be taken orally after meals. Daily dosage - no more than 4 tablets. A repeat course can be taken only a month after the last pill taken.

• Beviplex.

The drug is released in the form of a solution for intramuscular or intravenous administration. You can use no more than 2 ampoules per day. The duration of treatment is determined by the therapist.

• Neuromultivitis.

The product is taken after meals, 1 tablet up to 3 times a day. The required duration of treatment is prescribed by the therapist.

Taking the multivitamin Angiovit is justified only if there is a deficiency of B-group vitamins. But only a therapist should prescribe it and calculate the individual dosage, since synthetic drugs have a number of serious side effects.

Author: Shalunova Anna

Article design: Natalie Podolskaya

"Angiovit": analogues

The vitamin preparation “Angiovit” has no analogues in the structure of active ingredients, since the composition of the drug includes a rare combination of vitamins.

According to the pharmacological group, several drugs have a similar set of elements, therefore the following multivitamin complexes are analogues of Angiovit:

• "Antioxicaps" with iodine;
• "Alvitil";
• "Beviplex";
• "Aerovit";
• "Vectrum Junior";
• "Benfolipen";
• "Vetoron for children";
• "Vetoron";
• "Vibovit Junior";
• "Vibovit Baby";
• "Vitamult";
• "Vitabex";
• "Vitacharm";
• "Vitacitrol";
• "Gendevit";
• "Hexavit";
• "Dekamevit";
• "Heptavit";
• "Kaltsevita";
• "Jungle";
• "Makrovit";
• "Combilipen Tabs";
• “Multivita plus;
• "Multi Tabs";
• "Neurogamma";
• "Neurotrat forte";
• "Neuromultivit";
• "Pentovit";
• “Pikovit forte”;
• "Pikovit";
• "Multivitamin mixture";
• “Water for children”;
• "Revit";
• "Pregnavit F";
• "Revitalize";
• "Sana Sol";
• "Rikavit";
• "Stressstabs 500";
• "Stress formula 600";
• "Triovit Cardio";
• "Tetravit";
• "Foliber"
• "Undevit";
• "Unigamma".