All people have experienced a cold; it appears at different ages and does not depend on gender. The disease occurs with the appearance of a runny nose, as well as a sore throat, and the patient coughs.
In the modern world there are enough drugs that are ready to overcome the disease in a short time. Medicines are available in the pharmacy, thanks to the wide range, you can choose the right one, for example, Rengalin syrup.
Description of the drug
When treating colds that are accompanied by severe coughing with attacks, one of the best medications, Rengalin, works well.
It is often used in the treatment of both dry and wet coughs that produce thick secretions. Children as young as three years old can already use the medicine.
Rengalin syrup differs from other drugs in its complex therapeutic effect.
Using this medicine you can get rid of the following ailments:
- cure types of diseases;
- eliminate the development of ARVI;
- get rid of the flu.
In addition to the listed diseases, the syrup copes well with the appearance of inflammation in acute and chronic forms, which occur together with wet and dry cough.
How much does Rengalin cost? Price in pharmacies in Moscow and St. Petersburg.
The Russian drug in question is not the most common and it is not always available in pharmacies. If it was prescribed by a doctor, then ask where to buy the medicine. You can also try to purchase the medicine at an online pharmacy, especially since it costs much less there.
The easiest way to find solution and tablets in packs of 20 in pharmacies
| Preparative form | Price in online pharmacy, rub. | Price in pharmacy, rub. | ||
| Saint Petersburg | Moscow | Saint Petersburg | Moscow | |
| Tablets, 2 x 10 pcs. | 142 | 143 | 159 | 182 |
| Solution, 100 ml | 210 | 199 | 226 | 236 |
The Rengalin line of drugs are inexpensive, but if you can’t find them in pharmacies, you’ll have to use other cough remedies.
Compound
The medication consists of various substances that, in combination, cope well with inflammation, including cough:
- antibodies in purified form to bradykinin affinity - 0.12 g;
- antibodies in purified form to histamine affinity - 0.12 g;
- antibodies in purified form to morphine affinity - 0.12 g;
- a mixture consisting of 3 active water-based dilutions;
- the drug consists of excipients:
- multitol – 6.0 g;
- glycerol – 3.0 g;
- potassium sorbate – 0.165 g;
- citric acid – 0.02 g; purified water – 100 ml.
All of these substances together can eliminate the disease and prevent its development.
Rengalin solution for oral administration 100ml 112150
ATX:
R05DB Other antitussives
Pharmacological group
Other antitussives [Antitussives]
Nosological classification (ICD-10)
J02 Acute pharyngitis J04.2 Acute laryngotracheitis J05 Acute obstructive laryngitis [croup] and epiglottitis J06 Acute upper respiratory tract infections of multiple and unspecified localization J11 Influenza, virus not identified J22 Acute respiratory infection of neither
Compound
Lozenges 1 table active substances: antibodies to bradykinin, affinity purified * 0.006 dumbbells to histamine, affinity purified * 0.006 dumbbells to morphine, affinity purified * 0.006 g excipients: isomalt - 0.506 g, MCC - 0.0275 g; magnesium stearate—0.0055 g; anhydrous citric acid—0.005225 g; colloidal silicon dioxide—0.00275 g; sodium cyclamate—0.00275 g; sodium saccharin - 0.000275 g *Applied to isomalt in the form of a mixture of three active aqueous-alcoholic dilutions of the substance, diluted 10012, 10030, 10050 times, respectively. Solution for oral administration 100 ml active substance: antibodies to bradykinin, affinity purified * 0.12 dumbbells to histamine affinity purified * 0.12 dumbbells to morphine, affinity purified * 0.12 g excipients: maltitol - 6 g; glycerol—3 g; potassium sorbate—0.165 g; anhydrous citric acid—0.02 g; purified water - up to 100 ml *Added as a mixture of three active aqueous dilutions of the substance, diluted 10012, 10030, 10050 times respectively
pharmachologic effect
Pharmacological action: antitussive.
Directions for use and doses
Inside, outside meals. For one dose - 1 table. (keep in mouth until completely dissolved) or 1–2 teaspoons (5–10 ml). It is advisable to keep the solution in your mouth before swallowing for maximum effect of the drug. Take 1-2 tablets. 3 times a day or 1–2 teaspoons of solution 3 times a day. Depending on the severity of the condition, in the first 3 days the frequency of administration can be increased to 4-6 times a day. The duration of therapy depends on the severity of the disease and is determined by the attending physician.
Release form
Lozenges. In a blister pack made of PVC film and aluminum foil, 10 pcs. 1, 2 or 5 blister packs in a cardboard pack. Solution for oral administration. 100 ml in bottles made of OS brand glass or painted glass, sealed with tamper evident caps, with a PE dropper. Each bottle is placed in a cardboard pack.
. 127473, Russia, Moscow, 3rd Samotechny lane. 9. Tel./fax.Address of the place of production
Conditions for dispensing from pharmacies
Over the counter.
Storage conditions
At a temperature not exceeding 25°C. Keep out of the reach of children.
Best before date
3 years. Do not use after the expiration date indicated on the package. 2000-2017. Register of Medicines of Russia
Indications
acute and chronic diseases of the respiratory tract, accompanied by cough and bronchospasm; productive and non-productive cough with influenza and ARVI, acute pharyngitis, laryngotracheitis, acute obstructive laryngitis, chronic bronchitis and other infectious-inflammatory and allergic diseases of the upper and lower respiratory tract.
Contraindications
General for lozenges, oral solution: increased individual sensitivity to the components of the drug; children under 3 years of age, due to insufficient data on effectiveness and safety. For oral solution additionally: with caution: diabetes mellitus.
Use during pregnancy and breastfeeding
The safety of Rengalin in pregnant women and during breastfeeding has not been studied. During pregnancy and breastfeeding, the drug is used only if the expected benefit to the mother outweighs the potential risk to the fetus and child. The benefit/risk ratio is determined by the attending physician.
Description of the dosage form
Lozenges. Flat-cylindrical in shape, with a chamfer, a notch on one flat side, and solid edges; from white to almost white. On the scored side there is the inscription “MATERIA MEDICA”, on the other flat side there is the inscription “RENGALIN”. Oral solution. Colorless or almost colorless transparent liquid.
Pharmacodynamics
It has been experimentally shown that the components of the drug modify the activity of the ligand-receptor interaction of endogenous regulators with the corresponding receptors: antibodies to morphine - with opiate receptors; antibodies to histamine - with H1-histamine receptors; antibodies to bradykinin - with B1 bradykinin receptors; in this case, the combined use of the components leads to an increase in the antitussive effect. In addition to the antitussive effect, the complex drug, due to its constituent components, has anti-inflammatory, decongestant, antiallergic, antispasmodic (antibodies to histamine, antibodies to bradykinin) and analgesic effect (antibodies to morphine). Complex The drug Rengalin, due to modification of histamine-dependent activation of H1 receptors and bradykinin-dependent activation of B1 receptors, selectively reduces the excitability of the cough center of the medulla oblongata and inhibits the central links of the cough reflex. By inhibiting pain sensitivity centers in the thalamus, it blocks the transmission of pain impulses to the cerebral cortex. Inhibits the flow of pain impulses from the periphery due to a decrease in the release of tissue and plasma algogens (including histamine, bradykinin, PG). Alleviates the manifestations of acute pharyngitis, laryngitis and bronchitis, reduces bronchospasm. Relieves systemic and local symptoms of allergic reactions due to its effect on synthesis and release of histamine and bradykinin from mast cells.
Pharmacokinetics
The sensitivity of modern physicochemical methods of analysis (gas-liquid chromatography, high-performance liquid chromatography, gas chromatography-mass spectrometry) does not allow assessing the content of ultra-low doses of antibodies in biological fluids, organs and tissues, which makes it technically impossible to study the pharmacokinetics of the drug Rengalin.
Interaction
Lozenges. Cases of incompatibility with other drugs have not been registered to date. Oral solution. During the clinical studies conducted, no data were obtained on the interaction of the drug Rengalin with drugs used as concomitant therapy.
Overdose
Lozenges. Symptoms: possible dyspepsia caused by the excipients included in the drug. Solution for oral administration. Symptoms: possible dyspeptic symptoms (nausea, vomiting, diarrhea) caused by the fillers included in the drug (maltitol, glycerol). Treatment: symptomatic.
special instructions
For lozenges. Impact on the ability to drive vehicles and operate machinery. Rengalin does not affect the ability to drive vehicles and other potentially dangerous mechanisms. For oral solution in addition, patients with diabetes mellitus should remember that each teaspoon (5 ml) of the drug contains 0.3 g of maltitol, which corresponds to 0.02 XE. The metabolism of maltitol requires insulin, although due to slow hydrolysis and absorption in the gastrointestinal tract, the need for insulin is low. The energy value of maltitol is 10 kJ or 2.4 kcal/g, which is significantly less than that of sucrose. The energy value of 1 teaspoon of the drug is approximately 5.7 kJ (1.37 kcal). Effect on the ability to drive vehicles and machinery. Not studied.
Side effects
Individual hypersensitivity reactions to the components of the drug are possible. If these side effects get worse or the patient notices any other side effects not listed in the instructions, you should inform your doctor.
Possible product names
- Rengalin solution for oral administration 100ml
- RENGALIN SOLUTION FOR INTERNAL PRIM 100ML
- RENGALIN 100ML RR
- RENGALIN R-R D/ORAL FL. 100 ML X1
- RENGALIN SOLUTION FOR ORAL USE 100ML FL. No. 1
Release form
Available in:
- Tablets. The product has a chamfer and a mark; the tablets have a flat-cylindrical shape. For the sale of medicines, special contour cells made of PVC material are provided, or medications are also found in cells made of aluminum foil. All records are placed in a cardboard box.
- Syrup. In this form the drug is prescribed to children. Rengalin cough syrup contains components that are in tablets, only it is sold in dark-colored bottles. The drug is closed with a lid, and the kit includes a dosage spoon.
Rengalin or Ambrobene, which is better for a child?
Ambrobene is a German medicine that is available in the form of solutions for intravenous administration, oral administration and inhalation, tablets, capsules, and syrup. As the main component, it contains ambroxol, which thins thick mucus and promotes its evacuation from the respiratory tract. In a suitable dosage form, the medication is approved for productive cough in children from the first days of life. Mucolytic should not be used if you are allergic to its components and have an ulcer of the digestive tract in the acute stage. Treatment with medication can cause urticaria, Quincke's edema, rashes, shortness of breath, itching, anaphylaxis, nausea, abdominal pain, vomiting, diarrhea, stool retention, fever, impotence, headaches, runny nose, dry mouth, and urination problems. It is impossible to say unequivocally which drug is better; each medication has its own pros and cons, and the attending physician must select therapy for the child.
Pharmacodynamics and pharmacokinetics
Rengalin cough syrup has its own pharmacological effect, which is influenced by the main active ingredients, they are represented by antibodies.
Thanks to these components, the active compounds have a regulatory effect on histamine, bradykinin, and opiate receptors. They settle in the bronchi or lungs.
If the antibodies of a medicinal drug jointly influence the corresponding receptors, an antitussive effect will appear.
Thanks to the effectiveness of the medicine, the following symptoms of respiratory tract disease are reduced:
the severity of swelling decreases;- inflammation decreases;
- allergic reactions disappear;
- in the tissues of the lower respiratory tract after using the drug, rengalin reduces pain;
- in addition, the medication affects the relaxation of the smooth muscles located in the bronchi, thanks to the effectiveness of the drug, the lumen of the respiratory organs expands;
- the effectiveness of the drug can improve the air flow.
The main effect of the drug Rengalin is to exert a central effect on the medulla oblongata, eliminating cough syndrome. The medication differs from other drugs in that it has no effect on breathing, it is not capable of causing addiction, or causing drug dependence.
Contraindications and side effects
Rengalin for children is contraindicated if:
- age under 3 years;
- allergy to the composition of the medicine.
Rengalin solution, due to its maltitol content, is not suitable for children with genetic intolerance to fruit sugar; diabetics should drink it with caution.
The homeopathic remedy is usually well tolerated; only in case of hypersensitivity, it can provoke an allergic reaction. In this case, you need to stop using Rengalin and contact your pediatrician so that he can adjust the further treatment regimen.
When taking a homeopathic remedy, signs of intoxication may appear caused by the fillers included in the composition: glycerin, maltitol.
In case of an overdose of Rengalin, a child may experience:
- nausea;
- vomit;
- diarrhea.
If signs of poisoning appear, the drug should be interrupted. A specific antidote is unknown, so the victim is prescribed symptomatic therapy.
Indications for use
Rengalin has an antitussive effect.
In addition, the medicine has a number of effects:
- anti-inflammatory effect;
- analgesic;
- the drug has antispasmodic and anti-edematous effects;
- The tablets have a pronounced anti-allergenic effect.
Cough mixture is prescribed to patients who suffer from acute as well as chronic diseases affecting the upper and lower respiratory organs.
Rengalin is able to eliminate dry and severe coughs that appear as a result of infectious and inflammatory diseases.
Tablets cope with the following range of diseases:
- ARVI;
- bronchitis;
- eliminates flu;
- fights laryngitis;
- does not allow pharyngitis to develop;
- inhibits laryngotracheitis.
To purchase a solution or medication in tablets, patients go to pharmacy kiosks and buy without a doctor’s prescription.
Is Ascoril or Rengalin preferable for a child’s cough?
Ascoril is a combined Indian drug that is available in tablets and syrup. It contains bromhexine, salbutamol and guaifenesin as its main ingredients. The medication dilates the bronchi and promotes the discharge of thick, viscous sputum. Syrup can be given to children from 0 years old, and tablets from 6 years old with a wet cough, which is observed against the background of bronchitis, inflammation of the lungs and trachea, whooping cough and other respiratory infections. As a result of taking the medication, the child may develop allergies, dyspeptic disorders, insomnia, drowsiness, tremors, convulsions, and stained urine. Ascoril is prohibited in cases of intolerance to its composition, dysfunction of the liver, kidneys, heart, hyperthyroidism, high eye pressure, uncompensated diabetes mellitus, recurrent gastrointestinal ulcers. The pediatrician should decide whether Rengalin or Ascoril is better for the child, since these medications have different compositions, indications and contraindications.
Side effects
Patients who do not have a reaction to certain substances in Rengilin cough syrup tolerate the effects of the medication well.
Sometimes there are cases when adverse reactions appear after the drug. This is mainly observed due to poor tolerability of certain substances of the drug.
The medicine is based on antibodies, so the occurrence of unwanted reactions in the form of allergies cannot be avoided. Their manifestation is noticeable in the form of a rash on the skin, severe itching appears in the groin, as well as near the armpits.
The following side effects occur rarely:
- gastrointestinal disorder;
- vomit;
- stomach ache.
All of the above phenomena appear from excess amounts accumulated in the body. If such symptoms occur, there is no need to debug with a visit to the doctor.
First of all, reduce the amount of medication to the minimum that can maintain the therapeutic effect. If negative reactions do not disappear and continue to disturb the sick patient, you should stop taking the medicine and visit a doctor during this period.
Important information! The recommendations of the manufacturer, as well as the attending physician, should be taken into account. Thanks to these points, you can avoid the influence of negative phenomena that may arise from taking the medicine.
Expensive and cheap analogs of Rengalin, price of substitutes
Rengalin is a unique drug, that is, it has no analogues in its composition. However, there are medications containing other components that have a similar therapeutic effect. Here are some substitutes that are similar in action to the original:
- Tablets (Russian analogue) contain antibodies to histamine. They are recommended for the prevention of respiratory ailments, as well as for their treatment. They relieve inflammation and swelling and help strengthen the immune system. Cost – from 295 rub./20 pcs.
- Glycodin syrup (India). Contains dextromethorphan, terpene hydrate and levomenthol. Helps clear the bronchi from phlegm and get rid of cough. Unlike Rengalin, it does not have analgesic properties. The drug should not be taken if you have asthma. Average price 110 rub./100 ml.
- Libexin tablets with prenoxdiazine (Hungary). Pain reliever and help with cough. They have many side effects from the gastrointestinal tract. They cost from 400 rubles for 20 tablets.
- Bronholitin syrup (Bulgaria). The main compounds are ephedrine and glaucine. Eliminates swelling and cough. The medication has many contraindications; it inhibits psychomotor functions. Cost – 140 rub./125 ml.
- Codelac tablets (domestic analogue). Contains natural extracts and codeine. Cough medicine with analgesic effect. There are many contraindications and side effects. They cost 113 rubles for 10 pieces.
Overdose
Excessive use of the drug Rengalin can cause the following phenomena:
- nausea appears;
- the patient is vomiting;
- overdose causes diarrhea.
All of the following phenomena are caused by fillers contained in the medication:
- maltitol;
- as well as glycerol.
In this case, symptomatic treatment is used or it is recommended to completely abandon the drug Rengalin and use another, no less effective remedy.
Rengalin - instructions for use
The drug, made in the form of tablets or syrup, differs from the others in one feature - they do not need to be washed down.
Syrup
The cough medicine Rengalin in the form of syrup is used after meals. Before swallowing the medicine, you need to hold it in your mouth for a while.
Instructions for use of Rengalin syrup for adults:
- 1-2 teaspoons no more than 3 times a day.
- If the patient's condition is severe, Rengilin cough syrup must be taken at least 4-6 times a day in the first 3 days.
An experienced doctor will determine how much treatment you need. He will consider the severity of the disease and then prescribe treatment.
Pills
It is recommended to take the medication 2 hours after eating. You must keep the tablet in your mouth until it is completely absorbed.
Use during pregnancy
Pregnant and nursing mothers are allowed to use the medicine to relieve cough. The attending physician will definitely tell you whether it can be used or not.
To avoid negative effects on the health of the mother and child, you can refrain from using the drug.
Important information! It is necessary to pay attention to the fact that clinical trials have not been conducted on the drug during pregnancy, as well as during breastfeeding. The instructions indicate that the drug can only be used as prescribed by a specialist.
Use in childhood
Instructions for use of Rengalin syrup for children:
- Children under 3 years of age are not recommended to treat their respiratory tract with Rengilin syrup or medication in tablets.
- If the baby is 3 years old or older , the medication will not cause harm.
- The dosage is 5 ml of the product in one dose, this amount is intended for children from 3 years to 6 years.
- For patients aged 6-12 years , the medicine can be given 10 ml.
Is it better to give Erespal or Rengalin to a child?
Erespal is a French drug based on fenspiride. It is currently being discontinued and recalled from the pharmaceutical market due to the fact that it may have a negative effect on the function of the cardiovascular system.
Analogs
The pharmacy kiosk does not always have the drug Rengalin; instead, pharmacists offer similar medicines with a similar composition:
- Codelac-Phyto - refers to a combination product that has a pronounced expectorant effect. It consists of herbal ingredients that suppress the excitability of the cough center, and also eliminates a strong, incessant coughing attack. The established dosage will help eliminate the cough center and also reduce bronchial secretion.
- Glycodin - refers to a combined type of drug. This drug has a pronounced bronchodilator and antitussive effect. Due to the presence of a complex effect, the product has a strong effect on the respiratory and nervous systems.
- Cofanol - this type of drug has a pronounced expectorant, as well as antiallergic effect, as well as an antitussive effect. The drug has a central anticholinergic effect. Thanks to the product, it is easy to get rid of spasms, inflammation disappears, and there is also an analgesic effect.
- Broncholithin - it belongs to the combined type of antitussive, it has a bronchoantiseptic as well as bronchodilator effect. The cough center decreases after the effectiveness of the ingredient - glaucine. This drug has a weak adrenoletic effect together with a bronchospasmolytic effect. After use, the medicine is not capable of causing addiction or dependence.
Glycodin
Codelac phyto
Cofanol
Bronholitin
Pharmacology
During scientific observations, it was found that the constituent substances change the degree of ligand-receptor interaction, endogenous stimulants with certain receptors.
The complex product not only has an antitussive effect, but also, thanks to its constituent components, helps achieve antiallergic, antispasmodic and anti-inflammatory effects.
Rengalin selectively stops the main components of the cough reflex, reduces the sensitivity of the cough center in the medulla oblongata region of the brain, and prevents the entry of painful signals to the brain.
Compared to analgesics that have a narcotic effect, Rengalin is not capable of leading to respiratory depression, the emergence of drug dependence, and does not cause drowsiness.
Effective for diseases such as bronchitis, pharyngitis and laryngitis. Can be used at any stage of disease development.
Combats systemic and local signs of allergy due to its effect on the synthesis and removal of histamine from mast cells.
Conditions and shelf life
The medication is usually stored at the optimal temperature, which does not exceed 25 degrees. After use, place the medicine in a separate place where the child has no access.
It is prohibited to place the drug in the freezer and freeze it.
After purchasing Rengalin cough syrup, it is valid for 3 years from the date of manufacture.
When a product has expired, it is prohibited to accept it; it becomes unusable and can cause harm to human health.
Reviews
Parents' opinion
Parents who gave their children Rengalin for coughing noted that after the first day of use it became less frequent and during the day the child did not cough at all, although previously the attacks were severe, to the point of vomiting. The wheezing also goes away quickly. The solution and tablets have a pleasant taste, and even small children drink and dissolve them with pleasure. Negative reviews are due to the fact that a child may be allergic to Rengalin and the drug does not help everyone.
Opinion of Evgeny Olegovich Komarovsky
A well-known pediatrician believes that a homeopathic remedy has the same effect as a placebo - a dummy substance that does not have a therapeutic effect. One of the principles of homeopathy is treatment with small doses. Take a component and dilute it with water many times. Next, the liquid must be shaken vigorously so that it remembers the beneficial properties of this substance. The dilution is repeated several times; as a result, the last portion of water may not contain molecules of the original component at all. Next, the liquid, which has retained its beneficial properties, is combined with powdered sugar and the resulting mass is rolled into balls and given to the patient. This technology is used to produce homeopathic tablets, solutions and other dosage forms.
Scientists cannot explain the mechanism of action of homeopathic remedies and prove their effectiveness. Evgeniy Olegovich believes that when taking Rengalin for a cough, it is not medication that is used to treat, but faith, and many parents note that it only helps in combination with other medications.
Despite the fact that the homeopathic remedy is available without a prescription, it is prohibited to give it without the consent of the pediatrician. The specialist will select the dosage and tell you how many days to take Rengalin for the child.
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