Instructions for use of Rhodiola Rosea tincture

Rhodiola rosea is a plant that is considered medicinal. It can cure many diseases. People call it the golden root. The plant grows up to fifty centimeters in height, its flowers are yellow and its leaves are oblong. The color of the root is bronze-pearl. Radiola has long been used in medicine to prolong life and increase the body's defenses.

Compound

The root of the plant contains many useful substances. It contains glycosides that normalize the functioning of the cardiovascular system, flavonoids that are involved in the production of bile and urine, and activate the activity of the adrenal glands.

Rhodiola also contains anthrachions, which strengthen the immune system and have a laxative effect, salidroside, organic acids and essential oils, phenols, carbohydrates, coumarins, and sterols. In addition, the plant contains various trace elements, alkaloids, rhodiol flavonoside, gossypetin, anthraglycosides.

All these components help eliminate infectious diseases, viruses and inflammatory processes, relieve pain, stop bleeding, heal wounds, normalize all body systems, and stop the growth and development of cancer cells.

Release form and composition

The dosage form of the drug is extract: a dark brown liquid with a reddish tint, which has a characteristic aroma; During storage, sediment may form (the extract is packaged in dropper bottles and dark glass bottles, as well as canisters, in volumes depending on the manufacturer).

Composition per 1 liter of extract:

• active ingredient: rhizomes and roots of Rhodiola rosea – 1000 g;
• auxiliary component: ethanol 40% - in the amount necessary to achieve the required volume.

Price

The product can be bought at a regular pharmacy or ordered online. Its price depends on the release form and volume you choose. The approximate cost is shown in the table:

Release form of rosea rhodiola	Price in rubles
Tincture, 0.5 l	320-650
Extract, 30 ml	57-141
Tablets, 40 pcs.	140-168

Pharmacological properties

Pharmacodynamics

The active component of the extract is the roots and rhizomes of Rhodiola, including organic acids, tannins, b-sitosterol, essential oils, as well as two crystalline substances - rhodioliside and n-tyrosol, which have stimulating properties.

The drug has a general tonic effect, increases the body's resistance to adverse factors, such as environmental pollution, the action of viruses and pathogenic microflora, and the influence of low and high temperatures. Rhodiola liquid extract increases physical and mental performance, restores vital functions after illnesses.

Use in combination

This is an effective adaptogen that can be combined with the use of other dietary supplements. But first you need to consult with a specialist, since not all of them combine well with each other. When using other adaptogens, there is a risk of increasing the recommended dosage, which will lead to overstimulation and sleep disturbances.

Now Foods, 7-Keto LeanGels, 100 mg

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This is a unique complex, the composition of which is balanced and intended for those people leading an active lifestyle. The supplement is recommended for use by those who have intense physical and sports activities, or have an increased load on the immune system.

The complex includes 4 active components, each of which enhances the effect of the previous ones:

1. golden root stimulates and helps restore muscles after intense training, accelerates the elimination of waste products;
2. conjugated linoleic acid improves metabolic processes, accelerates fat burning and increases muscle growth. Used to reduce fat deposits in the abdominal area;
3. green tea extract increases vitality, gives energy and helps resist stress factors. It also has a positive effect on the cardiovascular system and brain activity;
4. acetyl-L carnitine accelerates metabolism, helps eliminate fat reserves, and increases endurance.

To maintain energy at the required level, you need to take 1 capsule per day with water.

Gaia Herbs, Adrenal Health, Daily Support

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The drug contains active components that ensure the health of paired internal organs. These are liquid vegetable capsules that do not contain alcohol, harmful or chemical compounds, or products of animal origin. Therefore, they can be used by vegetarians.

The nutritional supplement has a positive effect on the activity of the adrenal glands. If their function is impaired, a person may face not only stress, but also many diseases. The herbal remedy acts gently from the inside, helping to improve the functioning of internal organs in order to avoid serious disorders.

Thanks to its balanced composition, dietary supplements are quickly and easily absorbed and do not harm the body. In addition to rhodiola, the product contains vegetable glycerin, water, vegetable cellulose and olive oil.

To support adrenal health, take 2 capsules twice daily after meals. Contraindications for use are pregnancy, breastfeeding, and some diseases for which medications are used.

Indications for use

According to the instructions, Rhodiola liquid extract is recommended for use as a stimulant drug for the following diseases/conditions:

• asthenic syndrome;
• neurasthenic conditions;
• increased fatigue;
• neurocirculatory dystonia (NCD) of the hypotonic type;
• convalescence (the process of restoring normal functioning of the body after infectious as well as severe somatic diseases);
• mental/physical stress (work in extreme conditions);
• acute respiratory viral infections (ARVI) - for the purpose of prevention during epidemics.

The mechanism of the therapeutic effect of Rhodiola on the brain

Golden root has multiple positive effects on brain function. The medicinal plant can reduce stress and chronic fatigue, improve mood and prevent professional burnout. But how does he manage to do this?

So far, scientists have not been able to thoroughly describe the mechanisms that underlie the therapeutic effects of Rhodiola. Apparently, the bioactive substances of the plant involve several processes at once that can have a beneficial effect on the nervous system.

1. It is assumed that salidroside works as an inhibitor of monoamine oxidase A and B. That is, it prevents the breakdown of the neurotransmitters serotonin, dopamine and norepinephrine, which is important for the treatment of depression.
2. The extract reduces the activity of the enzyme catechol-O-methyltransferase, which, together with monoamine oxidase, breaks down dopamine and norepinephrine. It is a lack of dopamine, not serotonin, that causes depression in some people.
3. Salidroside affects the hypothalamic-pituitary-adrenal axis. This axis controls the body's response to stress by producing the hormone cortisol. Rhodiola suppresses the production of cortisol and thereby helps a person cope with chronic stress more easily.
4. Bioactive substances in R. rosea have a positive effect on the functioning of heat shock proteins, such as Hsp70, which help the body's cells cope more effectively with repeated stress.
5. Golden root enhances the activity of the AMPK protein (5′-AMP-activated protein kinase), which suppresses the development of inflammation in the brain, which is one of the prerequisites for depression, Alzheimer's disease and other disorders. Other manifestations of the extract’s work also have an anti-inflammatory effect on the brain, for example, its ability to reduce the production of pro-inflammatory cytokines.

Contraindications

Absolute:

• arterial hypertension;
• agitation, insomnia;
• febrile syndrome;
• period of pregnancy and lactation;
• children under 12 years of age;
• hypersensitivity to any of the components of the extract.

Relative: Rhodiola liquid extract is prescribed with caution for liver diseases, alcoholism, traumatic brain injuries, brain diseases, in childhood and adolescence from 12 to 18 years.

Interesting Facts

• The popular name of the culture is golden root or Siberian ginseng.
• Rhodiola was considered a sacred plant by the Persians, Gauls, and ancient Romans.
• Refers to powerful aphrodisiacs.
• The main purpose of drugs based on it is an adaptogen, along with Eleutherococcus.
• After planting in a summer cottage and collecting rhizomes, the soil will take 10 years to recover.
• Several centuries ago, smugglers sold Rhodiola at 1:100 gold weight.
• The plant is listed in the Red Book of several regions.
• It is grown on an industrial scale and is included in the official register of medicinal plants of the Russian Federation.
• Some peoples use the dried root as a talisman against the evil eye and evil spirits.
• The Druids considered an infusion of Rhodiola root to be a cure for all ailments.

Instructions for use of Rhodiola liquid extract: method and dosage

The extract is taken orally 15–30 minutes before meals, in the first half of the day.

Recommended dosage: 5-10 drops 2-3 times a day; The duration of the course of therapy is 10–20 days.

Patients with asthenia, akineto-hypotonic syndrome and other diseases of a psychoneurological nature should begin treatment by taking 10 drops 2-3 times a day, increasing the dose over time to 30-40 drops per dose; Duration of therapy is 1–2 months.

The healing effects of Rhodiola on the immune system

• Antioxidative activity. Bioactive substances of R.rosea activate protective mechanisms in the human body, which enhance its internal antioxidant work. This helps reduce oxidative stress and reduce free radical damage to fats, proteins and DNA.
• Salidroside turns off the JAK2/STAT3 genes, which are involved in the escalation of the inflammatory response.
• Rhodiola extract reduces the production of pro-inflammatory cytokines IL-1, IL-6 and TNF-alpha throughout the human body. The most significant benefits are seen in brain cells called microglia.

It may seem that rose root extract suppresses the immune system, and therefore can be dangerous, since inflammation is a protective function of the body. This is wrong. Like any other adaptogen, R. rosea in the correct therapeutic dosage suppresses inflammation only when needed. Today, people are much more likely to suffer from excessive inflammatory activity in the body, rather than from a lack of it.

Reviews of Rhodiola liquid extract

According to reviews, Rhodiola liquid extract, when taken in recommended doses according to indications, has a good tonic effect, gives strength and vigor, increases energy, improves immunity, and promotes concentration. Patients like the combination of the low cost of the drug with its high effectiveness.

Disadvantages include the absence of a measuring pipette for bottles without droppers, the presence of ethyl alcohol in the composition, and a possible increase in heart rate.

Effectiveness backed by scientific research

Golden root is recognized by official medicine, its effect has been well studied. Interestingly, most of the properties attributed to the plant have been confirmed in laboratory studies.

At the same time, trial courses of treatment were conducted on volunteers, statistical data was collected, on the basis of which the following results were obtained:

• with a course of taking 400 mg of a dietary supplement based on Rhodiola, nervousness and a feeling of fatigue objectively decreased, and concentration of attention increased;
• symptoms of “burnout” under stress have been relieved;
• symptoms of depression are eliminated.

In another experiment, research into the effectiveness of goldenseal-based medications noted that a control group of factory employees working night shifts were able to increase their productivity by 20% without symptoms of overwork.

It was also noted that the herb can improve performance, normalize sugar levels in diabetes, and also stop the development of cancer cells, which suggests that the plant extract can be used in the treatment of a number of cancer diseases.

Interaction of golden root tincture with other medications

1. Rhodiola rosea is allowed to be taken during treatment with antidepressants, serotonin reuptake inhibitors and MAO inhibitors only as prescribed by a doctor.
2. Diabetics taking metformin should only treat R.rosea after consulting their doctor.
3. The medicinal plant is capable of changing the activity of a group of enzymes known as cytochrome P450. These enzymes are involved in the breakdown of many groups of drugs, and therefore their combined use with Rhodiola can lead to serious side effects.

The most common medications metabolized by P450:

• non-steroidal anti-inflammatory drugs (aspirin, ibuprofen);
• anticoagulants (warfarin);
• drugs to lower blood pressure (losartan);
• anticonvulsants (phenytoin).

The list is not complete, so all people taking any medications on a regular basis should consult a doctor and only then begin treatment with Rhodiola rosea. Or at least read the instructions for your drug and see if it is metabolized by cytochromes P450. If yes, then self-medication with R.rosea should be abandoned.