Rumalon. Instructions for use in injections, indications, price, reviews

Degenerative diseases of the musculoskeletal system are persistently getting younger. Now not only elderly people, but also young, full of energy patients come to doctors with similar problems.

This is due to poor nutrition, physical inactivity, and incorrect lifestyle. The course of treatment for these diseases includes a group of chondroprotective drugs. The abundance of different brand names on pharmacy shelves confuses many, which naturally makes it difficult to choose the right drug.

In this article we will talk in detail about the drug "Rumalon" (a complex drug for the treatment of osteoarthritis). It contains an extract from cartilage and bone marrow of calves. "Rumalon" is produced in ampoules and is used for intramuscular injections.

Composition of the drug Rumalon in injections

The pharmacological agent is available only in the form of a solution for intramuscular administration. The drug is packaged in ampoules of 1 or 2 ml. The ampoules are in a cardboard box, which also contains instructions for use.

The main active component of the drug is a glycosaminoglycan-peptide complex, which has a therapeutic effect. Additionally, the solution contains metacresol and water for injection. The substance is an extract from bone marrow, cartilage tissue of calves or other young animals.

The solution is transparent and has a yellow-brown tint. The ampoules are made of dark glass, and there should be no sediment at the bottom.

Patient reviews

Many have already become familiar with the effect of the drug in complex treatment. Here are some useful reviews from patients who used Rumalon:

• Anna, 54 years old. The doctor prescribed Rumalon injections for me to treat arthritis. To get rid of severe pain and tightness, I took 3 injections a week. At first I didn’t feel any particular effect, but the doctor warned me about this. The effect of the drug occurred after 2 weeks of use. At some point I felt relief, all the pain went away. My course of therapy lasted 1 month. The doctor said that if symptoms recur, you can undergo another therapy in six months;
• Vasily, 49 years old. I have had problems with my joints for 2 years now, I feel pain and discomfort when walking. I went to the doctor and he prescribed a course of injections with Rumalon. This is a solution for intramuscular injection that helps cope with severe pain. I visited the doctor and took injections for 3 weeks. After completing the course, the unpleasant symptoms disappeared and mobility returned to the joints. I am completely satisfied with the effect of the drug, I feel light when walking;
• Maria, 60 years old. I was prescribed the drug Rumalon for the treatment of spondyloarthrosis at an advanced stage. At first, I did not feel the effect of the treatment and even wanted to stop going for injections. However, after 2 weeks there was a sharp improvement and the pain went away. I began to walk more actively without stiffness or discomfort. At the same time, during the entire course of treatment I did not experience any side effects or any complications. The drug really helped and coped with my illness.

Pharmacological properties

Rumalon in injections (indications for use are indicated in the instructions) has several pharmacological properties, among which chondroprotective properties are considered the most pronounced. The main active component is a natural biogenic stimulant, which provides this effect.

In addition, the medicine helps to suppress the activity of enzymes that have a destructive effect on joint joints, namely cartilage tissue. Additionally, the glycosaminoglycan-peptide complex relieves inflammation, improves blood circulation in the affected area, and promotes the restoration of cartilage cells.

Thanks to this, the patient’s tissues and motor activity are restored. The product has a positive effect not only on affected tissues, but also on healthy ones, which helps prevent relapse of the disease.

Pharmacodynamics and pharmacokinetics

The pharmacodynamics of the drug has been studied by specialists over a long period. Since the active component is a natural substance, its effect on the body of different patients may differ.

After penetration into the systemic bloodstream, the ingredient is concentrated in the affected joint or several joints. The substance acts on tissues and stimulates the formation of chondrocytes, while simultaneously blocking components that can slow down this process.

Additionally, the substance helps eliminate ingredients that can provoke the development of the inflammatory process. Another advantage of the product is the ability to normalize the amount of synovial fluid in the joint capsule, which facilitates friction of the heads of bones, reduces the load and prevents compression of tissues.

Glycosaminoglycan is the main active ingredient of Rumalon in injections

In addition, the medication improves blood circulation in the affected area and stimulates the formation of hyaluronic acid. This component is considered one of the most important for maintaining healthy joints.

Rumalon also helps to significantly slow down the progression of degenerative changes in the joints. This allows it to be used for the treatment of osteoarthritis and other diseases with similar manifestations.

The pharmacokinetics of the drug begins after intramuscular administration. The active components penetrate the muscle fibers and enter the systemic bloodstream. After this, they move towards the affected area. The highest concentration of the substance is found in connective and cartilage tissue. A slightly smaller amount is found in bone tissue.

The drug does not accumulate in the liver and other organs of the digestive system and is eliminated from the body within 24 hours after the last injection. In patients suffering from pathologies of the urinary system, the period of elimination of the drug is extended.

Analogues of the drug

If you experience an allergic reaction or Rumalon has insufficient therapeutic effect, you may need to change the drug. Analogues are:

1. "Biartrin." It is similar in composition and principle of action to Rumalon, since it is produced from tracheal cartilage and bone marrow of calves, and is also available in ampoules;
2. "Alflutop". Complex preparation from sea fish extract. Its active components are: hyaluronic acid, mucopolysaccharides, dermatan sulfates, chondroitin sulfate, magnesium, copper, iron and zinc;
3. "Mukosat." The main active ingredient is chondroitin sulfate. The drug is available in the form of tablets and capsules and also has a chondroprotective effect.

Biartrin

Alflutop Mukosat

You should not replace the prescribed drug with a generic one on your own. When prescribing an original drug, a doctor always knows what effect to expect and when. A generic drug may require longer use or may not be suitable at all for the treatment of a particular disease.

If you could not find Rumalon at the pharmacy (perhaps it seemed too expensive), contact your doctor. He will be able to select the correct drug that will help you.

"Rumalon" is an effective and natural biostimulant that will help save your joints from destruction, while returning you to your normal lifestyle.

Indications for use

Rumalon injections, the indications for use of which can be checked with a doctor, are prescribed for various diseases of the joint joints as the main or auxiliary method of therapy:

• Spondylosis and spondyloarthrosis.
• Restoration of the spinal column after injury.
• Osteochondrosis of initial and progressive stages.

  

• Arthrosis of the hip and knee joints, occurring in mild to severe forms. In the latter case, inflammation of cartilage and connective tissue is considered a concomitant manifestation.
• The period of restoration of the articular joint after a severe bruise or other injury.
• Chondromalacia at different stages, when rapid destruction of cartilage in the joint occurs.
• Meniscopathy, accompanied by impaired mobility and other symptoms.

The drug is quite often used as the main method of treatment for degenerative diseases of a chronic nature, in which frequent relapses are observed.

Effect of the drug

Rumalon reduces joint pain, increases mobility and relieves inflammation. Typically, the therapeutic effect occurs after 2-3 weeks of using the drug, and becomes maximum by 4-5 weeks. After the course of treatment, the effect lasts for several months.

If you use non-steroidal anti-inflammatory drugs (Diclofenac, Ibuprofen, Aspirin), then Rumalon will reduce their dose. This reduces the risk of developing gastritis and stomach ulcers.

At the same time, Rumalon increases the activity of anticoagulants (Heparin, Fraxiparin) and antiplatelet agents (acetylsalicylic acid, Warfarin). As a result, of course, bleeding may increase or spontaneous bleeding may occur.

If you take this drug together with anticoagulants or antiplatelet agents, then monitoring blood clotting function is required.

Contraindications

Despite the natural origin and relative safety of the medicine, its use is not always permitted.

The main contraindications are the following:

• Intolerance to the main active ingredient of the drug or additional ingredients.
• Age up to 12 years.
• Rheumatoid arthritis in the acute stage, when the patient is undergoing treatment with potent drugs.
• The period of pregnancy and breastfeeding.
• End stage renal failure.
• Liver damage.
• Oncological pathologies.
• Purulent process in the joint capsule.
• The recovery period after a stroke or myocardial infarction.
• Uncontrolled arterial hypertension.

  

  Read also:  Instructions for use of the combined antihypertensive drug Gizaar
• Severe blood pathologies.

It is not recommended to use the product without preliminary examination and identification of the cause of pain and other manifestations. Perhaps the symptoms are triggered by advanced arthritis, for which the medication is contraindicated.

When to use

The drug "Rumalon" is used to treat diseases of the joints, which are accompanied by thinning of the articular surfaces, changes in their configuration and destruction. This group includes:

1. Arthrosis of the interdigital joints;
2. Gonarthrosis;
3. Coxarthrosis;
4. Meniscopathies (deformation and thinning of one of the cartilages of the knee joint);
5. Osteoarthritis;
6. Recovery period after surgical interventions on the spine and joints;
7. Spondyloarthrosis;
8. Chondromalacia of the patella (destruction of the cartilage tissue of the patella).

Instructions for use, dosage of the drug

The drug is administered exclusively intramuscularly and always deeply, since full absorption occurs only in the deep muscle fibers.

The course of treatment lasts at least 6 weeks, and a specific regimen must be followed to achieve results. On the first day, 0.3 ml of the drug is administered, on the second - 0.5 ml. After this, the patient receives 1 ml of the drug three times a week.

The procedure is carried out in a clear sequence:

1. The patient is positioned on a couch in the manipulation room, freeing up space for the injection of the drug.
2. The nurse tells him about her actions and obtains consent to carry out the procedure.
3. Next, she draws the required amount of solution into a syringe with a long needle, having previously treated the ampoule with an antiseptic.
4. After this, a large area of ​​one buttock is treated with an antiseptic solution. In most cases, 70% alcohol and sterile cotton balls are used.
5. The next step is to treat a smaller area with a new sterile swab soaked in alcohol.
6. After this, the skin is punctured and the medicine is injected deep into the muscle. In this case, the patient may feel a slight burning or tingling sensation, which disappears a few minutes after removing the needle.
7. The puncture area is treated with alcohol again, after which a dry sterile cotton swab is applied.
8. The patient remains in the office until blood stops coming out of the puncture site. It may not be present, but in most cases it is present, even if the puncture site is chosen correctly and all requirements are met.

   

The patient is prohibited from leaving the office with a cotton swab, especially if there is blood on it. When administering the medicine, it is better for the patient to be in a horizontal position, which will allow the muscles of the buttock to relax as much as possible. In some cases, injections are given into the muscle at the front of the thigh. This is required if there are any inflammatory or purulent lesions in the buttock area.

The patient undergoes a course of therapy 2 times a year if he suffers from chronic degenerative-dystrophic joint disorders. If he goes to the doctor for the first time and receives the drug, the decision on re-prescription is made by a specialist after examination.

It is worth noting that the patient can receive injections in a hospital while undergoing treatment, as well as on an outpatient basis, visiting the facility only on the days when the solution is required. The decision is made by the doctor, taking into account the patient’s condition and concomitant diseases.

How to prick

"Rumalon" is used exclusively for intramuscular injections. To avoid allergic reactions, a biological test is performed before the first injection. To do this, 0.25 ml of solution is injected intramuscularly, and after 2 days - another 0.5 ml.

If you cannot tolerate the drug, you may experience the following side effects:

• Itching appears at the injection site;
• A rash appeared on the skin;
• An attack of suffocation or other allergic reactions occurred.

If you suffer from allergic diseases (bronchial asthma, a history of angioedema or anaphylactic shock), then the first Rumalon injections should be carried out only in the presence of the attending physician.

If the biological test does not reveal intolerance, then a course of the drug is started. "Rumalon" is administered 1-2 ml 2-3 times a week. In total, the course includes 15 injections of 2 ml or 25 injections of 1 ml. Typically the course takes 5 weeks. This treatment is repeated twice a year, and in especially severe cases - 3-4 times a year.

Side effects

If you follow the instructions, side effects are quite rare. But we should not exclude the possibility of their occurrence. Experts note that some patients experience headaches and dizziness. In advanced cases, migraine develops, the symptoms of which are difficult to relieve even with potent analgesics.

Sometimes dyspeptic disorders appear. The patient reports nausea, possible attacks of vomiting, spasms of the muscles of the stomach and intestines. In addition, flatulence, loose stools or persistent constipation develop.

Such manifestations are rare. Some patients report pain at the injection site. This is usually observed when the technique of introducing the solution is violated, the needle is chosen too short, or the patient is positioned incorrectly during the procedure.

In this case, when palpating the area where the solution was introduced, you can detect a hard area, when pressed, pain appears. Often, a blue or reddish hematoma forms at the site of puncture of the skin. It disappears 1-2 weeks after stopping the course.

The most common adverse reactions occur in the form of an allergy to the drug. First, the patient develops a small rash on the arms, legs, or torso. Gradually, the lesions increase in size, itching and peeling appear. The patient is forced to comb the affected areas, which leads to complications. It is possible that general symptoms may occur in the form of drowsiness, irritability, and lacrimation.

Side effects and contraindications Rumalon

Possible side effects of the drug include:

• Diarrhea;
• Constipation;
• Gastrointestinal disorder;
• The medicine may cause disorders of the nervous system;
• Dizziness;
• Headache;
• Allergic rashes on the skin;
• Dyseptic disorders.

Hyperemia or swelling may also appear at the injection site of the medicinal liquid. As a rule, these phenomena and other allergic reactions soon go away on their own.

Overdose

In case of an overdose of the drug, side effects may increase. A specific antidote has not been identified; hemodialysis is not advisable. In case of accidental overdose, symptomatic therapy is recommended.

Contraindications

Rumalon and drug analogues are not used for the treatment of rheumatoid arthritis, and they are also not prescribed for detected hypersensitivity. The medicine should not be used in pediatrics, during breastfeeding, or pregnancy.

Overdose

Rumalon in injections, the indications for use of which involve prescription for various forms of arthrosis, only in exceptional cases leads to an overdose. At the same time, all adverse reactions worsen, headaches intensify, as well as disorders of the digestive tract.

The patient notes increased nausea and vomiting. There is no relief after emptying the stomach. The most pronounced manifestations were recorded in cases of allergy to the drug. If the patient ignores the symptoms and continues the course of treatment, the symptoms worsen.

The rash becomes large and occupies large areas of the body. In most cases, blisters filled with clear liquid appear on the body, and the itching becomes unbearable. The patient scratches the affected areas, which can lead to infection of the damaged areas of the skin.

Sometimes urticaria does not appear in the form of blisters, but in the form of large bumps with jagged edges. They do not differ in color from healthy skin; lesions can only be seen under certain lighting or felt by touch.

When such lesions appear, itching is also present; when scratched, the skin becomes red, but the redness quickly disappears. In addition to external manifestations, swelling of the mucous membrane of the throat is possible, which causes difficulty breathing, even suffocation. If adverse reactions or symptoms of overdose occur, you should immediately stop the course and consult a doctor.

special instructions

Before starting a treatment course, the specialist recommends undergoing an examination, which necessarily includes a visit to a gastroenterologist and rheumatologist. The doctor makes sure that there are no contraindications for using the medication.

It is strictly forbidden to administer the drug intravenously or consume it orally. It should also be noted that the medicine cannot be mixed with other solutions for intramuscular administration in the same syringe. Rumalon should not be diluted with saline solution.

The doctor should warn the patient that in the first few days after the start of the course, the condition of the joint joints may deteriorate. This is observed in 80% of cases. Usually the condition improves after a few days, so temporary deterioration is not considered a reason to cancel the injections.

Why does the healing effect disappear?

Describing their experience of using this chondoprotector, most patients, regardless of the location of the pathology, note that the pain does not return for at least 4-5 months. After this period, joint pain reasserts itself.

Is this a reason to refuse the drug? Most people for years do not think about normalizing the load on the joints and spine, and the pain that arises is “drowned out” with painkillers and tablets. The joint requires restoration and nutrition. Without receiving it, he becomes exhausted.

In addition, the bulk of natural stimulators of tissue regeneration help maintain water balance in cartilage tissue and prevent the “drying out” of articular cartilage or intervertebral discs. They also have a mild anti-inflammatory effect. But all this is with long-term use.

For more information about how chondroprotectors act on joints, watch the video:

Like other chondoprotectors, Rumalon stimulates the production of chondrocytes, but 15-25 injections are not enough to fill all the structural “gaps” that form in cartilage tissue due to many years of nutritional deficiency.

The return of pain after some time does not mean the ineffectiveness of the medicine, but signals that the “margin of safety” of the cartilage tissue is running out, and the joint again needs a thorough replenishment.

Drug interactions

You should not use Rumalon and other drugs from the group of chondroprotectors at the same time. It is especially important to follow this rule if the patient wants to combine natural and synthetic medications. It is allowed to take chondroprotectors in the form of capsules, powders or tablets. This will not affect the effectiveness of Rumalon.

Since the drug is administered intramuscularly, experts allow the use of any oral forms of drugs simultaneously with the medication. They do not weaken the effect of the solution. However, it is not recommended to administer the medicine during chemotherapy.

It is allowed to combine treatment with Rumalon and chondroprotectors in the form of a gel or ointment. This will enhance the effect of the product and speed up the healing process.

Contraindications for use

In some situations, using the drug will be hazardous to health. Therefore, before injections, be sure to study a number of contraindications:

1. Allergic reaction of the patient to the composition of the drug;
2. Attacks of rheumatoid arthritis;
3. Dangerous for pregnant women;
4. Not prescribed during breastfeeding;
5. Dangerous for children.

To prevent the drug from harming your health, do not take it in the cases described above. If you are unsure whether you can use Rumalon, consult your doctor first.

Analogs

Rumalon in injections (indications for use should be known before starting a therapeutic course) has no structural analogues, that is, drugs that contain the same active components. But there are several products in solution form that have a similar effect, despite a different composition.

Any of the analogues has therapeutic properties, but the drugs can be used only after consulting a specialist.

Is there a worthy alternative?

Each drug manufacturing company must undergo recertification, and when Rumalon disappears from pharmacy shelves, the question arises: are there analogues, and preferably, cheaper?

Their chemical “actives” are different, and each of them has its own list of advantages and disadvantages.

Rumalon or Alflutop: which is better?

The range of therapeutic effects of Alflutop is limited to osteochondrosis, spondylosis and osteoarthritis. But the possibility of intra-articular injection allows it to be delivered directly to the “weak link”.

Alflutop is injected directly into the joint

The raw materials from which Rumalon is produced cause fewer negative reactions - when the drug is administered, skin rashes and itching may occur.

Alflutop is administered intramuscularly daily or twice a week - inside the joint. The average cost of a package of 10 ampoules of 1 ml is 1644 rubles, 5 ampoules of 2 ml are 1789 rubles.

Both drugs are not used during pregnancy or breastfeeding; with individual intolerance.

Which is better – Dona or Rumalon?

Dona is another stimulator of cartilage tissue regeneration, available in several dosage forms: capsules and powder for internal administration and solution for intramuscular administration.

In the chemical “arsenal” of the Italian Dona there is a natural component of articular cartilage, crystalline glucosamine sulfate, which has anabolic and chondoprotective properties. In addition to inhibiting enzymes that destroy cartilage, glucosamine sulfate initiates the “fixation” of calcium in the bones and normalizes the permeability of the joint capsule to nutrients.

The list of its indications includes osteoarthritis of any localization, chondromalacia of the patella, scapulohumeral periarthritis.

The drug Dona is available in several dosage forms

As with treatment with Rumalon, during the period of using Dona, infrequent reactions from the gastrointestinal tract are possible - bloating, constipation or diarrhea, and some skin manifestations of allergies - urticaria, itching.

The average cost of an Italian drug is:

• 1350 rub – 750 mg tablets 60 pieces;
• 1300 rubles – powder in bags (active ingredient – ​​1500 mg, 20 bags);
• 1300 rubles - solution for injection - ampoules 0.4 g, 2 ml, 6 pieces.

A brief review showed: each of the drugs has its own characteristics, which the doctor will help you understand. Health cannot be accumulated “for future use”, try to at least preserve it!

As a result of physical activity, inflammation and various injuries, the cartilage tissue of the joints becomes thinner and is gradually destroyed. For the treatment and prevention of such phenomena, special drugs have been developed - chondroprotectors, such as Rumalon.

The drug is prescribed to patients suffering from diseases of the musculoskeletal system, pathological processes accompanied by pain and damage to articular-cartilaginous tissues.

It contains a glycosaminoglycan-peptide complex of animal origin (cartilage extract and bone marrow), the positive effect of which on joints and bones has been known for a long time.

When the active component of the drug enters the human body, the sliding of surfaces in the joint improves, the metabolism in the cartilage shell is activated and stabilized, and the cartilage tissue is saturated with moisture.

Rumalon for injections, photo

The main active ingredient is GPC - a glycosaminoglycan-peptide complex. Belongs to the group of active biogenic stimulants of animal origin, has a pronounced chondroprotective (protective) effect, reduces the activity of most enzymes that have a destructive effect on the cartilaginous surface of the joint.

1 ml of solution contains a glycosaminoglycanopeptide complex in the amount of 2.5 mg.

Rumalon injections exhibit the following positive effects:

— activate the synthesis of connective tissue components; — prevent the destruction of joint tissues; - stimulate the production of joint fluid components; - have anti-inflammatory and antioxidant properties.

Price in pharmacies in Moscow, St. Petersburg, regions

The cost of the medication in pharmacies in Moscow and St. Petersburg reaches 1,900 rubles. per pack 10 ampoules. In the regions you can purchase medicine for 1400-1500 rubles. for 10 ampoules. A package of 25 ampoules costs approximately 2800 rubles. In large cities the price reaches 3,000 rubles.

Rumalon is one of the most popular chondroprotectors in injections. The product has several indications for use, helps improve the condition of affected joints, prevents complications, and also helps to avoid complete immobility of the joint.

Article design: Vladimir the Great

Prices

The original Rumalon is produced by Robapharm (Switzerland).

This medicine is the most expensive drug.

The cost for one package is 2300-2700 rubles.

Generics (official copies of the drug) produced by other pharmaceutical companies will help you save money.

For example, in Russia, Rumalon is produced by Bryntsalov-A. Its price is 1300-1500 rubles.

If you are not short on funds, then it is better to buy the original drug. Such drugs are safer for the patient, since when used, allergic reactions occur less frequently, and the therapeutic effect is more pronounced.