Urodan - instructions for use, doses, indications

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Published: 10/01/2020

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• Release form and composition Composition of the medicament

Release form and composition

The release form of Urodan is granules (in plastic jars of 100 g).

1000 mg of granules contain the following biologically active substances:

• methenamine – 3 mg;
• piperazine – 25 mg;
• bearberry (in the form of leaf extract) – 26 mg.

Auxiliary components: sugar – 19 mg, tartaric acid – 356 mg, disodium phosphate – 375 mg.

Composition of the drug

The active substances contained in the drug are the following:

• bearberry leaf extract;
• piperazine;
• urotropin.

The additional components are disodium phosphate and tartaric acid.

Composition and release form

Urodan is produced in the form of white granules, easily soluble in water.

The medicinal mixture Urodan includes 2.5 parts of piperazine phosphate, 2.5 parts of sodium benzoate, 8 parts of methenamine, 2 parts of lithium benzoate or citrate, 37.5 parts of sodium bicarbonate, 10 parts of disubstituted sodium phosphate, 37.5 parts of tartaric acid and 1 .9 g sugar. In addition, Urodan also contains a dry, highly concentrated standardized extract from the leaves of the bearberry plant.

Component Properties

Bearberry leaves, which are part of Urodan in the form of a dry, highly concentrated standardized extract, are among the natural antiseptics, due to which the dietary supplement has an anti-inflammatory, diuretic and disinfectant effect.

Cleansing the urinary tract from bacterial flora and inflammatory products is due to arbutin and tannins contained in Urodane.

The antimicrobial properties of the dietary supplement are associated with the glycoside arbutin, which breaks down into free hydroquinone and glucose.

The antiseptic properties of Urodan are determined by the local irritant and antimicrobial effect of hydroquinone. When it is excreted through the kidneys, irritation of the kidney tissue is observed, and increased urination also occurs. Thanks to hydroquinone, the activity of redox reactions increases. It has a significant effect on the following processes: metabolism, oxygen absorption by tissues, blood levels of potassium, glucose, glutathione, reduction of diabetic ketoacidosis.

The therapeutic effect of Urodan is enhanced by the specific action of hydrolysis products and tannins. In low concentrations, tannins block the growth of most microorganisms; in high concentrations, they act as antibacterial agents, which leads to the death of microbes.

Pharmacodynamics

A drug. containing a combination of active substances. When piperazine salts and Li+ with uric acid , easily soluble salts are formed, which are excreted in the urine. At the same time, the urine becomes alkalized.

The extract of bearberry leaves contains the glycoside arbutin , which, under the enzymatic action of arbutase , breaks down into glucose and hydroquinone . Hydroquinone enhances redox processes, has an irritating effect, affects metabolism and oxygen saturation of tissues, normalizes the concentration of glucose , potassium and glutathione , and also reduces the level of ketoacidosis in diabetes . The drug contains tannins that affect the pathogenic flora of the urinary tract and helps cleanse the products of inflammation.

Pharmacokinetics

piperazine and lithium salts, uric acid is transformed into easily soluble compounds and excreted through the kidneys.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

A drug. containing a combination of active substances. When piperazine salts and Li+ with uric acid , easily soluble salts are formed, which are excreted in the urine. At the same time, the urine becomes alkalized.

The extract of bearberry leaves contains the glycoside arbutin , which, under the enzymatic action of arbutase , breaks down into glucose and hydroquinone . Hydroquinone enhances redox processes, has an irritating effect, affects metabolism and oxygen saturation of tissues, normalizes the concentration of glucose , potassium and glutathione , and also reduces the level of ketoacidosis in diabetes . The drug contains tannins that affect the pathogenic flora of the urinary tract and helps cleanse the products of inflammation.

Pharmacokinetics

piperazine and lithium salts, uric acid is transformed into easily soluble compounds and excreted through the kidneys.

Side effects of the drug

Instructions for use of Urodan provide for the following side effects:

• Nausea;
• Pain in the stomach area.

In some cases, patients who have taken dietary supplements for a long time have experienced the following complications:

1. Problems with stool;
2. Tremor;
3. Headache;
4. Vomit.

If side effects occur, you should consult a doctor. A specialist will be able to select a worthy replacement for Urodan.

Pharmacodynamics

A drug. containing a combination of active substances. When piperazine salts and Li+ interact with uric acid, easily soluble salts are formed, which are excreted in the urine. At the same time, the urine becomes alkalized.

The extract of bearberry leaves contains the glycoside arbutin, which, under the enzymatic action of arbutase, breaks down into glucose and hydroquinone. Hydroquinone enhances redox processes, has an irritating effect, affects metabolism and oxygen saturation of tissues, normalizes the concentration of glucose, potassium and glutathione, and also reduces the level of ketoacidosis in diabetes. The drug contains tannins that affect the pathogenic flora of the urinary tract and helps cleanse the products of inflammation.

special instructions

The drug is not recommended to be used together with strong alcoholic drinks.

When used simultaneously with other drugs containing acetylsalicylic acid and quinidine, a decrease in Urodane is observed.

Impact on the ability to drive a car and operate machinery

Urodane does not affect the nervous system and psychomotor reactions when taken correctly. If there are side symptoms (tremor of the limbs, tonic convulsions), you should refrain from operating dangerous mechanisms.

Use in pediatrics

Urodane is prohibited from being used to treat children under fourteen years of age.

For liver dysfunction

The instructions do not contain any restrictions for taking the supplement for liver dysfunction. The list of contraindications does not include conditions associated with liver pathologies.

For abnormalities in kidney function

Urodane is intended for the treatment of pathologies of the kidneys and urinary system. There are no exceptions to the list of contraindications in the instructions.

Urodan - instructions for use, analogues, reviews, doses

Urodan price, where to buy

The price of the drug is currently difficult to find out, since it is almost impossible to buy Urodan in the Moscow pharmacy chain.

• Online pharmacies in Kazakhstan Kazakhstan

Education: Graduated from the Sverdlovsk Medical School (1968 - 1971) with a degree in Paramedic. He graduated from the Donetsk Medical Institute (1975 - 1981) with a degree in epidemiologist and hygienist. He completed his postgraduate studies at the Central Research Institute of Epidemiology in Moscow (1986 - 1989). Academic degree - Candidate of Medical Sciences (degree awarded in 1989, defense - Central Research Institute of Epidemiology, Moscow). Completed numerous advanced training courses in epidemiology and infectious diseases.

Mechanism of action

Thanks to bearberry leaf extract, the drug has an anti-inflammatory effect. Arbutin contained in the plant has a diuretic effect on the body, which has a beneficial effect on kidney function. In addition, bearberry has an antimicrobial effect, which makes it difficult for microbes to multiply.

Urodan is recommended to be taken as an additional remedy in conjunction with the treatment of kidney stones, gout, chronic polyarthritis, and also as an independent remedy for preventive purposes against the development of such diseases. This occurs as a result of the ability of Urodane's tannins to inhibit the proliferation of microbes and slow down their growth.

Impact on the ability to drive a car and operate machinery

Urodane does not affect the nervous system and psychomotor reactions when taken correctly. If there are side symptoms (tremor of the limbs, tonic convulsions), you should refrain from operating dangerous mechanisms.

• allergic manifestations;
• blood pressure disorders;
• rapid heartbeat combined with tremor.

Possible adverse reactions

• allergies (skin rashes, urticaria, angioedema),
• digestive disorders (bitterness and dry mouth, increased salivation, yellow tongue, heartburn, heaviness in the right hypochondrium, nausea, vomiting, bloating, diarrhea),
• shortness of breath, sore throat,
• instability of blood pressure, headaches, dizziness, weakness.

Cases of overdose may be accompanied by pronounced side effects and require gastric lavage and symptomatic therapy.

Cases of overdose may be accompanied by pronounced side effects and require gastric lavage and symptomatic therapy.

special instructions

The drug is not recommended to be used together with strong alcoholic drinks.

When used simultaneously with other drugs containing acetylsalicylic acid and quinidine, a decrease in Urodane is observed.

The instructions do not contain any restrictions for taking the supplement for liver dysfunction. The list of contraindications does not include conditions associated with liver pathologies.

Side effects of the drug

Instructions for use of Urodan provide for the following side effects:

• Nausea;
• Pain in the stomach area.

In some cases, patients who have taken dietary supplements for a long time have experienced the following complications:

1. Problems with stool;
2. Tremor;
3. Headache;
4. Vomit.

• Nausea;
• Pain in the stomach area.

Scheme for using "Urodan"

The product must be diluted with water before use. To do this, 1 teaspoon of powder is dissolved in 0.1 liter of liquid. The resulting product has a consistency similar to an effervescent suspension. The dietary supplement must be taken three times a day. If an attack of renal colic occurs, it is allowed to increase the frequency of taking Urodan to four times a day. The product is drunk thirty minutes before meals.

If there are appropriate indications, you can repeat the course again. In agreement with the doctor, “Urodan” is allowed to be used to prevent exacerbation of chronic kidney diseases.

Use during pregnancy

Urodane can be used during pregnancy, given the natural composition of the medicine. Before starting therapy, consult your doctor. The doctor will assess the risk to the fetus and the benefit to the mother and prescribe the necessary course of therapy.

Instructions for use

Urodan should be taken before eating, 1 teaspoon 3-4 times a day. The pre-granulated powder must be dissolved in warm boiled water to form a suspension (a teaspoon per ½ cup of water). You need to drink the entire suspension received (half a glass); a new solution should be prepared for the next dose.

Recommendations for use

Urodane is intended for oral administration (before meals).

The dietary supplement is taken 3-4 times a day, 1 teaspoon (after preliminary dissolution in 1/2 glass of water).

Instructions for use and dosage

One teaspoon of this product should be diluted in half a glass of water until an effervescent suspension is formed. Urodan's instructions note that the drug should be taken three to four times a day.

The duration of treatment is on average thirty days. If such a need arises, the therapeutic course can be repeated.

Before using Urodan analogues, you should consult your doctor. The method of using analogues may differ.

Urodan: analogues

List of drug analogues:

• Urosin. The drug includes methenamine, lithium benzonate. The medicine copes with bacteria in the urinary tract, helps remove stones from the body;
• Blemaren. The drug is considered one of the best remedies for the treatment of nephrolithiasis. The active components of the drug help reduce acidity, remove calcium, and slow down the process of crystal formation. Effervescent pills are effective against uric acid and calcium oxalate stones;
• Atophan. The drug is aimed at reducing the concentration of uric acid in the body and removing the substance. The medicine also copes with attacks of moderate and moderate pain.

The selection of an analogue depends on the patient’s condition and the characteristics of the course of the disease. It is prohibited to take any analogue on your own; entrust the choice of treatment to a professional.

• Urosine;
• Atofan;
• Allomaron;
• Zinhofen;
• Colchicine;
• Blemaren.

Active ingredients: 2.6 g bearberry extract (leaves), 2.5 g piperazine, 0.3 g methenamine

Related components: disodium phosphate, tartaric acid, sugar.

The drug is in the form of a granular mixture intended to restore a suspension. Packaged in 100 ml jars made of plastic. In a cardboard box: 1 container, instructions for use.

Since the dietary supplement has not been registered, analogues are prescribed instead of Urodan. Which of them will be the most effective should be determined by the treating specialist.

Esparma (Germany)

Price: table thorn. (80 pcs.) – 1107 rub.

Drugs from the group of drugs for the treatment of nephrourolithiasis. Designed for alkalization of urine in the complex treatment of kidney pathologies, dissolution of uric acid stones, while taking cytostatics and drugs that enhance the excretion of uric acid, in dermatology - as a symptomatic drug for porphyria.

The medicine has a multicomponent composition: it contains potassium bicarbonate, citric acid, and sodium citrate.

The product is available in the form of effervescent tablets or granulates for dissolution in liquid. Taken as a foaming liquid.

Dosage and duration of use - according to individual indications.

Pros:

• Helps
• Normal taste
• Convenience of reception.

Flaws:

• High price
• Not the same effect as Urodan.

Uralit-U

Plantextract (Germany)

Price: (280 g) – 1030 rub.

Medicines based on potassium sodium hydrogen citrate. Developed for the treatment of urolithiasis and urine alkalization.

Available in the form of a granular mixture for preparing a solution. It is taken three times a day after meals, and the evening dosage should be lower than the morning and afternoon dosage. Can be used over a long course (from 1 month to six months).

Blémarin

One of the most popular medications after Urodan, which has a beneficial effect on reducing the acidity of urine.
The active ingredients of the product help reduce calcium excretion and slow down the process of stone formation. Blemaren is recommended to be taken for neafrolithiasis, since the drug affects the breakdown of stones.

Urosine

On the pharmacological market it is an analogue of Urodan. Prescribed for the same indications for use, available in tablets.

Atofan

This medication contains alkaline salts, which helps reduce the accumulation of uric acid and slows down the process of formation of salt stones.

Solimok

This product is recommended for use as a prophylactic against the formation of stones. Available in granular form, intended for the preparation of a suspension.

Cyston

The effect of the drug Cyston is due to the properties of the components included in its composition. Didymocarpus stem contains isopedicin, pedicin, essential oil, pedicillin. Has pronounced diuretic properties. 4.5(23) Diseases of the urinary system, Cystitis, Urethritis, Gout, Urinary incontinence.

Urisan

The dietary supplement Urisan has a positive effect on patients with uric acid metabolism disorders (gout) and kidney diseases. 4.9(52) Gout, Kidneys, Genitourinary system.

Pharmacological properties of Urodan

Analogs of Urodan, like the drug itself, have anti-inflammatory, disinfectant and diuretic effects. Urodan granules contain a large amount of arbutin and tannins, which cleanse the urinary tract of inflammatory products and pathogenic flora. Arbutin glycoside, which is found in bearberry leaf extract, breaks down into free hydroquinone and glucose. This process occurs with the participation of the enzyme arbutase.

Hydroquinone has a local irritant and antimicrobial effect, promoting increased activity of redox processes, affects tissue absorption of oxygen and metabolism, has a regulating effect on the concentration of glucose, potassium, glutathione, and helps reduce ketoacidosis in diabetes.

Hydroquinone is excreted along with urine through the kidneys, which irritates the kidney tissue, resulting in increased urination. The tannins contained in Urodane block the growth of most microbes and prevent their reproduction.

According to reviews of Urodan, the drug also has an anti-gout effect. Lithium salts and piperazine, due to interaction with uric acid, are converted into readily soluble compounds that are excreted from the body in the urine. In this case, the pH of urine shifts to the alkaline side.

People's opinion

Reviews in the medical field and from buyers vary. Some did not experience any results or effects from the course they took, but Urodan helped others well.

Reviews from doctors:

It should be borne in mind that the treatment of any inflammatory process, gout or urolithiasis requires a long period.

The treatment course includes taking medications, and any physiotherapeutic procedures, dietary nutrition and other methods according to the indications and characteristics of the disease and the general condition of the patient. The dietary supplement Urodan is in most cases recommended as an adjuvant to the main treatment.

This is a good proven remedy. Before use, be sure to consult with your doctor who knows your medical history. This is important to avoid side effects.

Arkady Ivanovich, doctor

It is known that increased levels of uric acid affect the formation of stones and the development of related diseases. The drug Urodan shows positive results in the treatment of gout and urolithiasis, removing excess acid.

In addition, chronic diseases require regular use of medications as a preventive measure against relapse of symptoms. Urodane is quite suitable for such purposes.

After taking Urodan, your overall health improves and the likelihood of relapse decreases.

Elena Alekseevna, doctor

Patient reviews:

I took a course of Urodan for the treatment of gout for more than a month. I didn’t notice any changes for the better or any effect. The main thing is that there were no side effects, which is also pleasing.

Alexey, 48 years old

People, the treatment of any disease should be comprehensive and you should not expect a miracle from taking this drug, especially a dietary supplement. She was treating gout and taking Urodan in combination with other medications prescribed by the doctor. Inflammation has decreased and health has improved.

Svetlana, 57 years old

A good drug, no side effects, easy to drink, quite pleasant, the instructions clearly explain how to use it. However, it is very difficult to get it; it is no longer sold in city pharmacies (the first time I bought it at a pharmacy). Tell me where can I buy it?

Vladislav, 32 years old

Pros and cons according to patient reviews

Most patients who took Urodan report positive results and good effects after completing the course. It was noticed that small stones gradually dissolved by the end of the course of taking the drug.

Among the disadvantages of patients, you can hear about the occurrence of adverse reactions. In this case, you should remember that there are contraindications to taking the drug.

Reviews about Urodan

Reviews about the drug vary. Some patients complain of a lack of effect.

“... I used the medicine Urodan to treat gout. I practically didn’t notice any results and despite the advertising, the miracle didn’t happen.”

Other patients report significant improvement in well-being and reduction in inflammation. In all likelihood, many patients simply do not understand that treating gout is a long process and the use of Urodan does not exhaust the entire arsenal of drugs. In addition, in addition to medications, one should not forget about physiotherapy, spa treatment, and diet therapy.