ACC Long 600 mg and its composition: instructions for use, analogues

ACC Long 600 mg instructions for use, as well as questions and answers and reviews about the use of this cough remedy.

Effervescent tablets with a higher dosage for adults as a “shock force” against a debilitating cough - an effective and proven remedy with blackberry flavor.

The main advantage and difference between ACC Long and other versions is the increased dosage of acetylcysteine, which allows you to take the medicine once and quickly achieve relief. When there is a speech, conference, or important event coming up, this medicine can be very helpful.

pharmachologic effect

The product has a mucolytic effect. Since the structure of the acetylcysteine ​​molecule contains sulfhydryl groups, this ensures the rupture of disulfide bonds of acidic mucopolysaccharides of sputum. As a result, the viscosity of the mucus decreases.

ACC Long is also active if the patient produces purulent sputum.

Provided that the drug is used for the purpose of prevention, the severity and frequency of exacerbations in people who suffer from cystic fibrosis and chronic bronchitis .

Description of the cough medicine ACC Long: composition

ACC belongs to the group of mucolytic drugs. The drug is also an expectorant and detoxifying agent. It effectively thins mucus and removes it very well from the lungs and bronchi. In addition, it relieves inflammation and improves the secretomotor functions of the body. It is often prescribed for treatment in adults and children .

The main component of the ACC drug is acetylcysteine. The drug also contains several excipients:

• lactose;
• carbonate;
• sodium bicarbonate;
• lemon acid;
• citrate;
• ascorbic acid;
• blackberry flavor.

The last substance in the medicine gives it a blackberry aroma. After entering the body, the drug affects mucopolysaccharides in sputum. The drug reduces the viscosity of mucus secreted by the bronchi. It is active even in purulent inflammations .

The medicine is produced in the form of round, flat-cylindrical, white, effervescent tablets that quickly dissolve in water. The reconstituted solution is clear and colorless with a blackberry aroma, sometimes with a faint sulfuric odor. Sold in polyethylene tubes, packed in cardboard boxes.

The medicine is also produced in the form of granules and powder. 1 tablet of ACC Long contains 600 mg of the main substance. There is 100 mg of it in powder, 200 mg of acetylcysteine ​​in granules. Another form of release is cough syrup.

Indications for use

The main active ingredient in the drug ACC Long is acetylcysteine, which has a mucolytic effect. Once in the body, it facilitates the discharge of sputum . It directly affects the rheological properties of sputum. The medicine also retains its activity against purulent sputum. According to the instructions, it can be used for the following diseases:

• pneumonia;
• sinusitis, asthma;
• acute or chronic bronchitis and bronchiolitis;
• tuberculosis;
• pulmonary eczema;
• cold;
• otitis media of the middle ear.

The tool also has other features. It is very often used in the treatment of diseases with large accumulations of purulent mucus. These are mainly protracted or mild inflammatory processes of the nasopharynx.

Doctors recommend taking ACC Long only for a wet, productive cough. It is effective when viscous or too thick sputum accumulates in excess quantities in the bronchi.

Pharmacokinetics and pharmacodynamics

Once in the body, it is absorbed quickly. Metabolism occurs in the liver, resulting in the formation of a pharmacologically active metabolite - cysteine , also cystine , diacetylcysteine , mixed disulfides.

When taken orally, the bioavailability level is 10% (as there is a pronounced first-pass effect). The highest level of concentration in the blood is determined after 1–3 hours. 50% bound to plasma proteins. Excreted from the body through the kidneys. The half-life is approximately 1 hour; if liver function is impaired, the half-life is 8 hours. Penetrates through the placental barrier. There is no evidence of penetration through the BBB.

Indications for use

ACC Long is used in the following cases:

• for diseases of the respiratory system that are accompanied by the formation of viscous sputum, which is difficult to separate (acute and chronic bronchitis, laryngotracheitis , obstructive bronchitis , bronchiectasis , pneumonia , cystic fibrosis , bronchiolitis , bronchial asthma );
• acute and chronic sinusitis
• otitis media.

Contraindications

ACC 600 is contraindicated for use in the following cases:

• during pregnancy and breastfeeding ;
• when the patient is under 14 years of age;
• with high sensitivity to the components of the drug.

The drug is used with caution for stomach and duodenal ulcers during exacerbation, for pulmonary hemorrhage, hemoptysis, varicose veins of the esophagus, bronchial asthma , diseases of the adrenal glands, as well as for liver and kidney failure .

Compatibility and contraindications

Acetylcysteine, which is part of ACC Long, is on the list of vital drugs and has great promise not only for the treatment of cough, but also for eliminating the symptoms of schizophrenia. And by combining acetylcysteine ​​with glycine in experiments on mice, scientists discovered that the substance can prolong life and save from heart attack.

At the same time, this substance is quite complex in terms of adverse reactions, especially in combination with other medications. It puts a strain on the liver, gastrointestinal tract, and can cause bleeding. Therefore, you can combine ACC with antibiotics and other substances only after consulting a doctor.

It has been established that ACC Long 600 is NOT COMPATIBLE with the following antibiotics:

• Penicillins of semi-synthetic origin such as Amosin, Flemoxin, Solutab, Ecobol.
• Tretracyclines – Unidox Solutab, Vibramycin;
• Aminoglycosides - Kanamycin, Streptomycin, Neomycin, Gentomycin, Tobramycin, Amikacin.
• Cephalosporin series - Zinnat, Ceftin, Zinacef.
• Amphotericin B.
• Antibiotics Amoxicillin, Loracarbef, Cefuroxime can be used after the recommendation of a doctor, after 2 hours after taking ACC.

There is also a complex Italian antibiotic together with acetylcysteine ​​- Fluimucil-antibiotic IT. Available as an injection kit. Price from 600 to 1000 rubles.

ACC Long compatibility and contraindications table:

It is necessary to understand that the dose of ACC Long is large, and very few tests have been carried out with other drugs. Therefore, if in doubt, it is better to take a quarter of the tablet, wait about 8 hours (drug elimination time) and then further increase the dose. And, of course, serious medications should only be taken with a prescription.

Side effects

The following side effects may occur during treatment:

• nervous system: in rare cases - tinnitus, headaches ;
• digestive system: stomatitis , vomiting , diarrhea , nausea , heartburn ;
• heart and blood vessels: tachycardia , low blood pressure;
• allergies: bronchospasm (in isolated cases - mainly in patients with bronchial hyperreactivity), urticaria , skin rash, itching ;
• other manifestations: bleeding - in isolated cases.

Adverse reactions and answers to questions

The following side effects are also possible when using ACC:

• Tachycardia, increased blood pressure;
• Allergic reactions, rash, itching, swelling, shock, Stevens-Johnson and Lyell syndromes;
• Tinnitus, headache, bleeding;
• Stomach exacerbations, nausea, heartburn.

Questions and answers on the use of ACC 600 mg:

Effervescent tablets ACC Long, instructions for use (Method and dosage)

The drug 600 mg is usually prescribed to patients over 14 years of age. The instructions for use of ACC Long 600 stipulate that the patient should take 1 effervescent tablet per day, this dose corresponds to 600 mg of acetylcysteine.

The tablet is dissolved in 1 glass of water and should be taken immediately after the tablet has dissolved. It is allowed to take the prepared solution for two hours in exceptional cases.

If we are talking about colds, then treatment continues for 5-7 days. If it is necessary to treat other diseases that have a longer course, the duration of therapy is determined by the doctor. People with chronic bronchitis are given longer treatment to ensure infection is prevented.

The drug is taken after meals.

When treating with ACC tablets, it is recommended to take additional fluid to ensure an enhanced mucolytic effect.

Dosage for children and adults (and overdose)

For ACC Long 600 mg, the dosage is intended exclusively for adolescents over 14 years of age and adults. This is a kind of “first aid”, which is taken at the rate of 1 tablet per day.

Can children have ACC Long? It is forbidden.

But if there are no tablets with a lower dosage in the house, you can divide the tablet into several parts. Naturally, everyone does this at their own peril and risk.

Dosage in the table

The duration of treatment is no more than 7 days. For cystic fibrosis and bronchitis, the period of administration may be extended, however, it is determined by the doctor.

Overdose: occurs if you take more than 1 tablet of 600 mg. Symptoms: nausea, diarrhea, heartburn, nausea. In case of slight excess (for example, you accidentally took an extra pill), it is recommended to drink plenty of liquid.

Attention! If a child has taken several tablets of ACC Long, or an adult has pain symptoms, hemoptysis, tachycardia, then you need to immediately call an ambulance and try to rinse the stomach!

Features of administration: ACC are effervescent tablets or powder; a healthy person can take it on an empty stomach before meals. But given that the composition includes ascorbic and citric acid, and the dosage is high, it is better to take the tablet after meals. The best time to take it is in the morning, after breakfast.

Interaction

In the case of simultaneous use of acetylcysteine ​​and cough suppressants, due to suppression of the cough reflex, the likelihood of mucus stagnation increases. Therefore, such medications must be combined with caution.

If treatment with acetylcysteine ​​and nitroglycerin , the vasodilatory effect of nitroglycerin may be enhanced.

Acetylcysteine ​​is not compatible pharmaceutically with a number of antibiotics (cephalosporins, penicillins, Erythromycin , Amphotericin B , Tetracycline ) and with proteolytic enzymes .

tetracycline decreases . In this regard, it is necessary to observe an interval between taking these medications of at least 2 hours.

If acetylcysteine ​​comes into contact with rubber or metals, sulfides with a characteristic odor are formed.

special instructions

It is important to use ACC Long with caution to treat patients with bronchial asthma and obstructive bronchitis. In this case, it is necessary to ensure systematic monitoring of bronchial patency.

If side effects occur during therapy, you should stop taking it and consult a specialist.

It is recommended to dissolve the tablets in glass containers to avoid contact with rubber, metal, and easily oxidized materials.

Patients with diabetes should take into account that one tablet corresponds to 0.01 XE.

Analogs

Level 4 ATX code matches:
Mukolik

Abrol

Ambrosan

Bronchorus

ACC 100

ACC 200

ACC

Mukolwan

Lazolvan

Bromhexine 8

Bromhexine 8 Berlin-Chemie

Bromhexine

Bronchobos

Carbocisteine

Erdomed

Pulmozyme

Pectolvan C

Halixol

Ambrobene

Acetylcysteine

Analogs of the drug ACC Long are ACC , N-AC-ratiopharm , Acetylcysteine , N-acetylcysteine , Acestine , Fluimucil , Mucomist , Mukobene , Muconex , etc. The most optimal drug should be selected individually by a specialist.

ACC Long price, where to buy

The price of 600 mg tablets is from 320 rubles for 10 pieces. Packaging of the drug 20 pcs. can be purchased at a price of 420 rubles.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine

ZdravCity

• Acc Long tablets spike.
  600 mg 10 pcs. Hermes Arzneimittel GmbH/Salutas Pharma, GmbH RUR 356 order
• Acc Long tablets spike. 600 mg 20 pcs. Hermes Arzneimittel GmbH/Salutas Pharma, GmbH

  RUR 697 order

Pharmacy Dialogue

• ACC long (tab.spike.600mg No.20)Hexal AG

  RUR 644 order

• ACC long (tab. spike 600 mg No. 10) Hermes

  425 rub. order

  Read also:  “DONA” (injections): instructions for use, price, analogues
• ACC long (tab.spike.600mg No.20)Hermes

  RUR 756 order

• ACC long (tab. spike 600 mg No. 10) Salutas Pharma GmbH

  RUR 347 order

show more

Pharmacy24

• ACC Long 600 mg No. 10 effervescent tablets Salutas Pharma GmbH.,Nimechchina/Hermes Artsnaimittel Gmb.H.Nimechchina
  146 UAH.order
• ACC Long Lemon 600 mg N6 tablets Salutas Pharma GmbH, Nimechchina

  130 UAH order

Prices and cheap analogues

The country of origin is Germany, the drug is produced by Hermes Arznaimittel, Salutas Pharma and Sandoz factories. Effervescent tablets are offered in two boxes - 10 and 20 pieces.

Prices in Moscow pharmacies (prices are similar in Russia) in rubles:

As you can see, the average price for No. 10 is 350 rubles, for No. 20 – 530 rubles. For many people this is expensive, so a list of cheap analogues of ACC Long-600 will be useful:

The cheapest analogues of ACC Long are the tablets “Mukaltin” and “Bromhexin”, which have been reliable and proven products since Soviet times. They help, but the effect is not so quick, and besides, you will have to take them in a course, while ACC, Vicks, Acetylcysteine, Fluimicil can be taken in one tablet for the whole day.

And, of course, analogues do not have such a pleasant taste, although in reality it is possible to achieve a similar effect for a price several times lower.

The original ACC Long contains lactose and vitamin C, and Vicks Active (this is the cheapest direct analogue) contains aspartame.

All three analogues are selling well in Russia. It would seem that their active ingredients are the same, why have three identical drugs? But one patient does not like the taste, another has lactose intolerance, and a third has a stomach ache from the cheaper product due to harsh citric acid.