Antigrippin - instructions for use of effervescent tablets and powder

Good day, dear readers! Today we will analyze the drug antigrippin and its composition. I often observe that my colleagues, and I myself sin, at the first symptoms of a cold, start taking anti-grippin. I asked the doctor, Ilona Valerievna Ganshina, to tell us about this wonderful medicine. I give her the floor.

With the transition to the autumn-winter period, the human body is at high risk of contracting respiratory viral infections and influenza. This trend is associated with a change in temperature conditions and a decrease in the body’s defenses against the background of autumn immunodeficiency. When faced with viral diseases, the main task is correct and timely treatment.

The drug antigrippin has established itself as a powerful anti-influenza agent with a wide range of therapeutic effects. The clinical effect of this drug was noted by many positive reviews from patients. What properties the product has and which antigrippin is better will be described in detail below.

Composition of Antigrippin

The analgesic drug is available in two forms: effervescent tablets and powder for oral solution. Their composition:

Release form and composition

The active ingredients of Antigrippin are paracetamol, ascorbic acid and chlorphenamine. The combination of auxiliary components depends on the form of release of the drug. As a rule, these are citric acid, sucrose, sodium bicarbonate, aspartame, povidone, sorbitol, sodium saccharinate, macrogol, sodium carbonate, various flavorings and taste correctors, etc.

Antigrippin is sold in the following dosage forms:

• Powder for preparing a solution for oral use, honey-lemon or chamomile. Consists of particles ranging from pure white to light brown or beige. Interspersed with brown or dark brown color are allowed. Has a specific smell;
• Effervescent tablets with raspberry or grapefruit flavor. They have a round flat shape, as well as a beveled edge and a dividing line on one side. The color of the tablets depends on the flavor used: with raspberry flavor - pink or pinkish-lilac, with grapefruit flavor - white or creamy white. They have a specific fruity or citrus smell;
• Effervescent tablets. They have a flat round shape and a beveled edge. On one side of the tablet there is a separation line. Color – white or almost white, slightly marbled. Smell: light fruity;
• Effervescent tablets for children. They have the standard flat round shape for all Antigrippin tablets, a beveled edge and a dividing line. Color – pink, with randomly located darker or lighter inclusions. They have a fruity smell.

Pharmacodynamics and pharmacokinetics

The properties of the combination drug depend on its ingredients. The instruction indicates the properties of the components:

1. Paracetamol – exhibits antipyretic, analgesic properties, relieves pain and fever.
2. Vitamin C - ascorbic acid regulates the processes of oxidation-reduction, carbohydrate metabolism, increases the body's resistance.
3. Chlorphenamine is a histamine receptor blocker, an antiallergic component that facilitates nasal breathing, reduces the feeling of nasal congestion, eliminates itching, sneezing, lacrimation, and redness of the eyes.

Antigrippin - antibiotic or not?

Patients taking Antigrippin often worry whether it is an antibiotic. According to the instructions, the drug does not contain antibacterial components, therefore it cannot belong to this group of drugs. The medication does not kill the infection and viruses that cause the disease, but only corrects the symptoms of its manifestation. The use of the drug is relatively safe.

Action of the medication

The drug is used for the symptomatic treatment of colds. It easily eliminates symptoms such as pain in the head and muscles, fever, nasal congestion and excessive snot. The Antigrippin analogue should have the same properties. However, the components included in the composition may differ.

Depending on what type of drug you choose, its effect will be individual. When using powder or effervescent tablets, the temperature is reduced and pain is eliminated. If you use Antigrippin Anvi capsules, you will get a pronounced analgesic effect. The drug will also help to narrow blood vessels and eliminate swelling in the nose. The medicine “Antigrippin Maximum” also has an antiviral effect due to the content of rimantadine in it.

Directions for use and dosage

Instructions for use of Antigrippin differ for each release format, but all types of medicine are taken orally. The duration of use should not be more than three days when using the product as an antipyretic, and more than five days as an analgesic. In case of pathologies of the kidneys, liver, or in old age, the interval between doses increases (up to 8 hours).

Antigrippin powder

Patients over 15 years of age are recommended to take antigrippin powder, one sachet 2-3 times a day. The contents of the sachet are dissolved in a glass of warm water, and the solution is drunk immediately. It is optimal to take the product between meals. No more than three sachets per day with intervals between doses of 4 hours. For older people, you can take the solution every 8 hours.

Antigrippin tablets

Antigrippin effervescent tablets are allowed to be taken by patients over 15 years of age. You should take one tablet dissolved in a glass of warm water (50-60 degrees) 2-3 times per day. You can take a maximum of three tablets per day. A minimum of 4 hours should pass between doses of the dissolved product. For pathologies of the liver and kidneys, the interval between doses should be increased to eight hours.

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Children's Antigrippin

Antigrippin effervescent tablets in pediatric dosage can be taken by patients over three years of age. Up to five years, the dose will be half a tablet twice a day. Children 5-10 years old need to take one tablet twice a day, teenagers 10-15 years old - one tablet 2-3 times a day. The dose is dissolved in a glass of warm water, the solution is drunk immediately, the interval between doses should be at least 4 hours.

Powder "Pharmacitron"

The next substitute for the drug “Antigrippin” can be called the drug “Pharmacitron”. It is available in two versions: an enhanced form (650 mg of paracetamol) and a regular form (500 mg). There are also antihistamine components and ascorbic acid. If you study the instructions for this drug in detail, you will find out that it is used not only for viral and bacterial diseases to relieve symptoms. The medication is prescribed for any pain syndrome: neuralgia, myalgia, arthralgia, and so on. This analogue is used with extreme caution for diseases of the prostate gland, liver and kidneys. Suitable for use in children only after 6 years.

The enhanced form of the drug, Pharmacitron Forte, is not prescribed to children under 14 years of age. It is advisable to use the drug in a lower dosage if the drug is ineffective. It is prohibited to simultaneously use medications containing paracetamol.

special instructions

In the instructions for use of Antigrippin there is a special instructions section. It contains the following information:

1. When combining therapy with Metoclopramide, Cholestyramine, Domperidone, you should consult a doctor.
2. With long-term use of doses of the drug exceeding those recommended by the instructions, there is a possibility of disruption of the liver and kidneys. It is necessary to monitor the blood condition.
3. Paracetamol and vitamin C can distort laboratory tests to determine the level of glucose, uric acid, bilirubin, and liver enzyme activity.
4. If the drug is prescribed to patients with rapidly developing, metastatic and proliferating tumors, then ascorbic acid can aggravate the process.
5. If the iron content in the body is high, it is recommended to reduce the consumed dose of vitamin C to a minimum.

Comparison of drugs

It is known that the instructions for substitutes for the drug “Antigrippin”: analogues are taken for viral diseases and influenza. Medicines are also used in the complex treatment of bacterial infections. All medications are effective for high fever, headache, chills. The drugs contain an antihistamine complex, which helps relieve nasal congestion, eliminate sneezing and lacrimation. However, the strength of action of the described agents may differ.

The weakest medicine of all those presented can be called “Agri”. The advantage of the drug is its low cost. The downside is its dubious effectiveness. You can highlight the medicine “Anvi Max”. Unlike others, this drug has antiviral activity, which can significantly shorten the period of illness. It is worth mentioning the Teraflu powder. It contains two antihistamines, which are not found in other analogues. "Theraflu" effectively copes with its task, eliminating the signs of rhinorrhea for a long time. Coldrex also has a distinctive feature. It contains caffeine. This component improves tone and increases performance. After using it, you can quickly return to your business and forget about the disease for several hours.

During pregnancy

The use of Antigrippin tablets and powder during pregnancy is contraindicated because the active components penetrate the placental barrier and can cause damage to the fetus. If you are breastfeeding (lactation), you should also not take medications based on paracetamol and chlorphenamine, because they are found in breast milk.

Popular "Fervex"

Another analogue of the drug “Antigrippin” is “Fervex” powder. This medicine has been present on the pharmacological market for a long time. Like the original medicine, Fervex has different flavoring additives. The drug is in high demand among consumers. It is often taken without first consulting a doctor. The cost of this medication is about 400 rubles for 8 sachets. This is more expensive than the drug Antigrippin.

The composition of the medications is approximately the same. Fervex contains 500 mg of paracetamol and 200 mg of ascorbic acid. The medicine is distinguished by the third component. Instead of chlorphenamine, the manufacturer uses pheniramine in an amount of 25 mg. The effectiveness of the drug has been proven for years. The medicine relieves fever and pain, reduces inflammation, eliminates nasal congestion, rhinorrhea and lacrimation. The result, according to users, is noticeable within 30 minutes after administration. It is contraindicated to use this substitute (analog) of “Antigrippin” for stomach ulcers, kidney and liver failure, alcoholism, as well as for children under 15 years of age. It is known that the medication can be used in the second trimester of pregnancy for certain indications.

Drug interactions

You should study the drug interactions of Antigrippin with other medications in order to be aware of possible dangers. Instructions for use contain this section:

1. Combining the drug with antidepressants, antipsychotics, antiparkinsonian drugs, phenothiazine derivatives leads to an increased risk of side effects.
2. The combination of the drug with glucocorticoids increases the likelihood of developing glaucoma.
3. Simultaneous use of Antigrippin with Isoprenaline reduces the chronotropic effect of the latter.
4. The drug reduces the effect of neuroleptics, tricyclic antidepressants, tubular reabsorption of amphetamine, alkaloids, anticoagulants, salicylates, sulfonamides, and tetracycline antibiotics.
5. The combination of the drug with Phenytoin tablets, Rifampicin, barbiturates, Phenylbutazone leads to the development of severe intoxication and increased excretion of Antigrippin.
6. Cimetidine reduces the risk of hepatotoxicity of the drug.
7. Diflunisal increases the concentration of paracetamol in the blood plasma and leads to manifestations of hepatotoxicity. Barbiturates reduce the effectiveness of paracetamol and increase the rate of excretion of ascorbic acid.
8. Paracetamol reduces the effect of uricosuric drugs and benzylpenicillins.

Side effects and overdose

According to studies, the medication is well tolerated in the doses recommended by the instructions. Rare side effects are:

• fatigue, headache, overexcitement;
• nausea, epigastric pain;
• hypoglycemia, development of coma;
• anemia, hemolytic anemia (with deficiency of glucose-6-phosphate dehydrogenase), thrombocytopenia;
• anaphylactic shock, Quincke's edema, itching, skin rash, urticaria;
• hypervitaminosis;
• hyperhidrosis;
• metabolic disorders;
• heat;
• constipation;
• dry mouth;
• accommodation paresis;
• urinary retention, hyperoxaluria, crystalluria;
• drowsiness.

Overdose can occur due to exceeding the dose of paracetamol or chlorphenamine. Signs of paracetomol poisoning include diarrhea, increased sweating, decreased appetite, abdominal pain, nausea, stomach discomfort, vomiting . Symptoms of an overdose of chlorphenamine include convulsions, dizziness, depression, agitation, and drowsiness. Symptomatic treatment is carried out.

Contraindications

The medication is prescribed with caution for renal and liver failure, congenital hyperbilirubinemia, and viral hepatitis. The instructions highlight contraindications for the use of Antigrippin:

• hypersensitivity to the components of the composition;
• prostatic hyperplasia;
• malignant neoplasms;
• phenylketonuria;
• exacerbation of erosions, ulcers of the gastrointestinal tract;
• angle-closure glaucoma;
• children up to three years of age for effervescent tablets.

Analogs

Drugs with the same active composition or a therapeutic effect similar to it can replace the medication. These include:

• AntiFlu – powder, tablets containing phenylephrine, paracetamol, chlorphenamine;
• Grippostad - analgesic granules for preparing a solution based on paracetamol, vitamin C;
• Coldrex - tablets, syrup, powder containing caffeine, ascorbic acid, phenylephrine, terpene hydrate, paracetamol;
• Coldact Flu - capsules and suspensions based on paracetamol, phenylephrine, chlorphenamine;
• Panadol – antipyretic tablets containing paracetamol;
• Solpadeine – antipyretic tablets, capsules based on paracetamol, codeine, caffeine;
• TeraFlu - flu powder containing paracetamol, phenylephrine, pheniramine;
• Fervex - powder based on paracetamol, vitamin C, pheniramine;
• Efferalgan - effervescent tablets, suppositories and syrup containing paracetamol.

How to replace medicine: popular analogues

Currently, there are a lot of alternative drugs to the drug "Antigrippin". Analogues can be absolute or structural. In this case, all active ingredients are the same. You can also replace Antigrippin with a relative analogue. In such a situation, the effect of the drug will be the same, but its composition will be different. Let's consider what alternative you can choose for the described medication.

• "Anti Flu Kids" (USA).
• "Agri" (Russia);
• "Anvi Max" (Russia);
• Fervex (France);
• "Theraflu" (USA, France);
• Coldrex (UK);
• Pharmacitron (Canada).

You can replace the medicine with other drugs, for example, Paracetamol. "Antigrippin Anvi" has analogues in the form of tablets with the trade names "Analgin", "Baralgin". For children, the substitute “Spazdolzin” is used. Let's take a closer look at alternative means.

Price of Antigrippin

You can buy the drug through pharmacies or the Internet at a cost that is affected by the type of release, the volume of the pack and the trade markup. Approximate Moscow prices: