During the season of colds and various viral epidemics, every person tries to protect themselves from infection. There are certain preventative medications for this. Such medications can also cure the disease. This simply uses a different dose of medication. One such remedy is Arbidol Maximum. Instructions for use, price, reviews of the medication will be presented to your attention in the article. You will learn about the composition of the antiviral drug. It is also worth mentioning how the medicine is used to treat children.
Release form and composition
The drug is available in the form of capsules (weight 376 mg): No. 0, gelatin hard, white; inside the capsules - a mixture of granules and powder, the color of the mixture - from white or white with a greenish-yellow or cream tint to light yellow or light yellow with a green tint (10 pcs. in blister packs, 1 or 2 packs in a cardboard pack and instructions for use of Arbidol Maximum).
1 capsule contains:
- active ingredient: umifenovir hydrochloride (in the form of umifenovir hydrochloride monohydrate) – 200 mg;
- auxiliary components: calcium stearate, potato starch, povidone (kollidon 25), microcrystalline cellulose, croscarmellose sodium, aerosil (colloidal silicon dioxide);
- composition of the capsule body and cap: titanium dioxide (E171), gelatin.
The cost of the medicine and its analogues
You have become aware of the information provided about the drug “Arbidol Maximum” in the instructions for use. The price of the medicine is on average 500 rubles per package. It is worth noting that medications in lower dosages are correspondingly lower. So, tablets for children of 50 mg of active ingredient will cost you only 200 rubles.
Among the analogues of the medicine with the same active ingredient are “Arpeflu”, “Arpetol”, “Immusstat” and so on. However, there are other means that can have a similar effect on the human body. They have different active ingredients. The trade names of such drugs are “Ocillococcinum”, “Isoprinosine”, “Ergoferon”, “Tamiflu”, etc. It is worth noting that many analogues of the described drug are much cheaper. However, this does not mean that you need to change treatment on your own. Contact your doctor first and get qualified advice and recommendations.
Pharmacological properties
Pharmacodynamics
Arbidol Maximum is an antiviral agent that has the specific ability to suppress in vitro influenza viruses A and B (Influenza virus A, B), including highly pathogenic subtypes A(H1N1)pdm09 and A(H5N1). In addition, the drug is active against such causative agents of acute respiratory viral infections (ARVI), such as coronavirus (Coronavirus) associated with severe acute respiratory syndrome, adenovirus (Adenovirus), rhinovirus (Rhinovirus), parainfluenza virus (Paramyxovirus), respiratory syncytial virus (Pneumovirus). The mechanism of the antiviral action of the drug is similar to fusion inhibitors. By interacting with the hemagglutinin of the virus, it prevents the fusion of the lipid membrane of the virus and cell membranes. It has a moderate immunomodulatory effect and helps increase the body's resistance to viral infections. Studies confirm the activity of the drug in relation to the induction of interferons. By stimulating cellular and humoral immune responses, the number of lymphocytes in the blood increases, especially T cells (CD3). Without affecting the level of T-suppressors (CD8), the drug increases the number of T-helper cells (CD4). The immunoregulatory index is normalized, the phagocytic function of macrophages is potentiated, and the number of natural killer cells – NK cells – increases.
For viral infections, the therapeutic effect of Arbidol Maximum is manifested by a decrease in the severity and duration of the disease. Taking the drug reduces the risk of complications caused by viral infection and exacerbations of chronic bacterial pathologies.
Arbidol Maximum is a low-toxic drug and in recommended doses does not have a negative effect on the human body.
Pharmacokinetics
When taken orally, umifenovir is rapidly absorbed and distributed to organs and tissues. The maximum concentration (Cmax) in blood plasma is achieved 1.2 hours after taking the drug at a dose of 50 mg, 1.5 hours at a dose of 100 mg.
Metabolized in the liver.
The half-life (T1/2) ranges from 17 to 21 hours.
During the first day, 90% of the dose taken is eliminated. About 40% is excreted unchanged: the main part (38.9%) is excreted in bile, a small amount (0.12%) is excreted in urine.
What opinions do you have about the medicine?
Consumers say that the drug "Arbidol Maximum" is very effective. The instructions for use confirm this information and indicate that the maximum concentration of the active substance is observed after just a few hours. Gradually the drug accumulates in the tissues. The substance reaches its maximum in the human body two days after the start of treatment. It is from this period that the patient becomes much easier.
Patients report that using the drug in capsule form is very convenient. One per dose is enough, whereas tablets (50 mg each) would need to be taken 4 pieces. You can often find information from women who used this medicine even in the early stages of pregnancy. In this case, the doctor prescribed a prophylactic dose (200 mg per day). Recovery came quickly, the medicine did not affect the fetus - the babies were born absolutely healthy after that.
Doctors report that today the drug “Arbidol” is one of the most popular and safe. It is taken by people of all ages for a wide range of symptoms. The medication not only eliminates pathology, but when used correctly, can increase the body's immune defense.
Indications for use
- prevention and treatment of influenza A and B, ARVI (including forms complicated by bronchitis and pneumonia), severe acute respiratory syndrome;
- chronic bronchitis, pneumonia, recurrent herpetic infection - as part of complex therapy;
- prevention of infectious complications after surgical operations.
In addition, Arbidol Maximum is prescribed as part of complex therapy for acute intestinal infections of rotavirus etiology in children over 12 years of age.
special instructions
Use during pregnancy and lactation. Use of the drug during pregnancy is contraindicated. It is not known whether the active substance of the drug or its metabolites passes into breast milk in women during lactation. If it is necessary to use the drug, you should stop breastfeeding. Impact on the ability to drive vehicles and machines. Does not exhibit central neurotropic activity and can be used in medical practice by people of various professions, incl. requiring increased attention and coordination of movements (transport drivers, operators, etc.).
Arbidol Maximum, instructions for use: method and dosage
Arbidol Maximum capsules are taken orally before meals.
Recommended dosage:
- nonspecific prophylaxis during an epidemic of influenza and other acute respiratory viral infections: 1 pc. 1 time every 3 days, course duration – 21 days;
- prevention of viral infection after direct contact with patients with influenza or other acute respiratory viral infections: 1 pc. 1 time per day for 10–14 days;
- treatment of influenza and other acute respiratory viral infections with uncomplicated course of the disease: 1 pc. 4 times a day with an interval of 6 hours. Course duration – 5 days;
- treatment of influenza and other acute respiratory viral infections complicated by the development of bronchitis, pneumonia and other pathologies: 1 pc. 4 times a day with an interval of 6 hours for 5 days, then continue taking 1 capsule. 1 time every 7 days for 28 days;
- complex therapy of acute intestinal infections of rotavirus etiology in children over 12 years of age: 1 pc. 4 times a day with an interval of 6 hours for 5 days;
- nonspecific prevention of severe acute respiratory syndrome (in contact with a patient): 1 pc. 1 time per day for 12–14 days;
- treatment of severe acute respiratory syndrome: 1 pc. 2 times a day for 8–10 days;
- chronic bronchitis, pneumonia, herpetic infection (as part of complex therapy): 1 pc. 4 times a day with an interval of 6 hours for 5–7 days. Then 1 pc. take 1 time every 3 days for 28 days;
- prevention of postoperative complications: 1 pc. 1 time per day for two days before surgery, then 1 pc. on the second and fifth days after surgery.
Summarizing
We talked about the fairly popular and widespread medication “Arbidol”. Instructions for use, price, analogues of the medicine are presented to your attention above. Despite all the positive qualities and safety, the drug can cause side effects. They are usually characterized by an allergic reaction in the form of a rash and hives. Abdominal pain and indigestion occur less frequently. If such symptoms are detected or there is no effect within five days of treatment, you should visit your doctor as soon as possible. Get well soon!
Use during pregnancy and lactation
The results of animal studies confirm the absence of harmful effects of the drug on the intrauterine and postnatal development of the child, on the course of pregnancy and labor.
The use of Arbidol Maximum is contraindicated in the first trimester of pregnancy and while breastfeeding.
The drug can be prescribed in the second and third trimesters of gestation for the prevention and treatment of influenza only in cases where the expected therapeutic effect for the mother outweighs the potential threat to the fetus.
If it is necessary to use capsules during lactation, breastfeeding should be discontinued.
Contraindications to the use of capsules
What does the instructions for use say about this about the drug “Arbidol Maximum”? The abstract states that the remedy is homeopathic and therefore has no contraindications for use. However, doctors do not advise prescribing this form of medication to children under 12 years of age or to patients weighing less than 40 kilograms.
The drug is not recommended for use during pregnancy and breastfeeding. The medicine is not prescribed if there is hypersensitivity to one of the components.
Comparison of side effects of Arbidol and Arbidol maximum
Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.
Arbidol's side effects are almost the same as Arbidol's maximum. They both have few side effects. This implies that the frequency of their occurrence is low, that is, the indicator of how many cases of an undesirable effect of treatment are possible and registered is low. The undesirable effect on the body, the strength of influence and the toxic effect of Arbidol are similar to Arbidol maximum: how quickly the body recovers after taking it and whether it recovers at all.
Effect on the body
The main pharmacological effect of the drug is antiviral. The substances in the drug suppress influenza B and A viruses, their highly pathogenic subtypes, rhinovirus, adenovirus, and parainfluenza. It has a negative effect on viruses that provoke the development of many dangerous pathologies, not necessarily the respiratory type, ARVI.
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By increasing resistance to viral pathogens, it has an immunomodulatory effect. Moderately stimulates the activation of the immune system. Increases the content of leukocytes in the blood. The molecules of the drug destroy the cells of viruses that penetrate the body, while simultaneously developing resistance to viruses and producing antibodies. The toxic effect on the body has not been confirmed; if used correctly, there is no negative result.
Already in the first stages of use, an improvement in well-being is noted : vigor appears, the disease is tolerated more easily. As for preventive measures, there is no obvious effect on the body; the person simply does not succumb to infection, enduring the epidemic steadily. For example, the absence of flu, when there are a lot of “infection carriers” around.
Important! The drug should be taken as a means of therapeutic treatment. Only long-term, correct use will reduce the duration of an infectious viral disease, reduce the risk of infection, and minimize the possible exacerbation of chronic bacterial pathologies.
Many people, when starting a course of treatment, try to find out whether Arbidol is an antibiotic or not . Experts explain that it is definitely not. A pharmacological product has a single purpose - to suppress viral microorganisms, destroy them, and promote the generation of antibody cells in the patient’s body. It turns out that this is an immunostimulant, but not an antibiotic, since it has nothing in common with this product.
Absorption of the active ingredients occurs quickly. Already an hour or two after oral administration of the capsule, the blood plasma is filled with the maximum amount of substances. The metabolic process takes about 21 hours, sometimes up to 17 hours. 40% of the drug is excreted in its original content by bile and kidneys. On the first day of administration, excretion is carried out in higher concentrations, about 90% of the received dose is excreted.
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Where to buy Arbidol Maximum capsules 200 mg No. 10 Falkenstein
The drug is delivered throughout Russia and the CIS. The goods are paid for only upon receipt. As a rule, the price for Arbidol Maximum capsules 200 mg No. 10 Falkenstein in pharmacies is much higher than on the Internet. You can consult and get more detailed information about the product by entering contacts on the official website, the operator will call you back within a few minutes.
The discounted price on the official website is 577 rubles.
Go to the official website Arbidol Maximum capsules 200 mg No. 10
