Instructions for Dapoxetine: how to properly use the best drug for early ejaculation

Sexual dysfunction can significantly complicate the family life of any man. The most significant of them are erectile dysfunction and premature ejaculation. If a man delays their treatment, then it will become impossible to have sex at all - complete impotence will occur. However, timely treatment will allow the possible threat to be eliminated in a timely manner. So, to get rid of early ejaculation and prolong the time of sexual intercourse, we recommend paying attention to the drug Dapoxetine.

Related article: Is it profitable to buy Dapoxetine in online pharmacies?

Purpose, release form and composition of the drug

Dapoxetine is a drug for the treatment and prevention of premature ejaculation in men aged 18 to 64 years. Available in the form of biconvex round tablets, which are gray in color, separated by a line and coated with a film. On one side there are numbers 30, 60 or 90, which indicate the dosage of the tablet in milligrams (mg). The main ingredient is a substance called dapoxetine hydrochloride. Depending on the dosage of the tablet, it can be 30, 60 or 90 mg.

Additional ingredients of Dapoxetine are:

• lactose monohydrate (43.88 mg for a 30 mg dosage and 87.76 mg for a 60 mg dosage);
• microcrystalline cellulose (14.6 and 29.2 mg, respectively);
• croscarmellose sodium (4 and 8 mg);
• silicon dioxide (2.5 and 5 mg);
• magnesium stearate (1.4 and 2.8 mg).

The film shell consists of the following ingredients:

• lactose monohydrate (2 mg for a 30 mg dosage and 4 mg for a 60 mg dosage);
• hypromellose (1.4 and 2.8 mg, respectively);
• titanium dioxide (1.1 and 2.3 mg);
• triacetin (0.4 and 0.8 mg);
• dye – black oxide (0.016 and 0.067 mg);
• dye – yellow oxide (0.0005 and 0.0001 mg).

Drug interactions and special instructions

Dapoxetine should not be combined during drug therapy with drugs such as Tramadol and Tryptophan. The drug should not be used together with medications for schizophrenia, depressive disorders and HIV.

The potency regulator should not be used in combination with sleeping pills or during antibiotic therapy.

If any of these medications are used by the patient, then the interval between the end of their use and the start of the therapeutic course of Dapoxetine should be at least 14 days.

Dapoxetine is intended only for men with premature ejaculation.

The drug is not compatible with alcohol; when used together, alcoholic drinks enhance the effect of Dapoxetine on the central nervous system and the neurocardiogenic side effects of ethanol. Therefore, patients should be advised to refrain from drinking alcohol while using Dapoxetine.

The drug Dapoxetine should not be taken by patients with a history of mania/hypomania or bipolar disorders; if symptoms of these diseases appear, the drug should be discontinued.

When carrying out therapy in patients with controlled epilepsy, careful monitoring of the body's condition is required.

When using the drug, dizziness, impaired attention, fainting, blurred vision and drowsiness may occur, therefore, during the period of drug therapy, it is recommended to refrain from driving vehicles and technical mechanisms that can pose a danger to a man’s life.

Pharmacological action of Dapoxetine

The mechanism of action of Dapoxetine is aimed at inhibiting the reuptake of serotonin by neurons, in parallel with this there is an increase in the action of neurotransmitters on nerve receptors. The onset of ejaculation is controlled by the nervous system. Dapoxetine delays the onset of ejaculation, reducing the time it takes for nerve impulses to travel to the cerebral cortex. Thus, the medicine makes it possible to have sex 3-4 times longer.

The ingredients of the drug are absorbed into the blood within a short period of time, the maximum concentration of Dapoxetine in the body is observed 2-3 hours after its use. The duration of action of a tablet with a dosage of 60 mg. is about 7 hours. The drug is completely excreted from the body along with urine 1 day after use. Eating fatty foods somewhat reduces the effectiveness of Dapoxetine, or rather by about 10%. However, the medicine can be taken at any time, regardless of food.

What is it for?

Sexual dysfunction disorder can be of various types. Dapoxetine is indicated for use in men if the following disorders are observed:

• premature ejaculate;
• short duration of sexual intercourse;
• uncontrolled ejaculation;
• reduced potency.

Fast ejaculation

It must be understood that the medicine was not developed to cure male ailments. It primarily prevents rapid ejaculation. The manufacturer’s official website clearly states that the product is a prolongator, that is, an “extender” of sexual intercourse.

It is impossible to say unequivocally whether Dapoxetine treats male impotence, but, as many men say in reviews, after a full course there is a noticeable improvement in potency. If we talk about the declared effect, in the next two to three hours after administration, you can indeed completely control the release of ejaculate.

The effect of Dapoxetine in patients of different categories

Thus, the pharmacokinetics of the drug turned out to be somewhat different in people of different races and ages. Use 60 mg. Dapoxetine administered to European and Japanese men resulted in a faster onset of action in the Asian country. Doctors associate this fact with the lower body weight of people of the Mongoloid race. Duration of action of Dapoxetine at a dosage of 60 mg. in men of different ages (under 65 years and older) it was the same. But the period of elimination of the drug from the body was longer in elderly men over 65 years of age.

Interaction of the drug with other drugs

In fact, there are many medications that cannot be taken with Dapoxetine. This group includes some strong painkillers, in particular the drug Tramadol, as well as some antibiotics.

In addition, dapoxetine hypochloride reacts poorly with medications used to treat clinical depression (monoamine oxidase inhibitors) and schizophrenia. Lithium-based drugs, which are used to correct bipolar disorders, are also at risk. Potentially dangerous drugs include those used in the treatment of migraines, as well as some herbal medicines, in particular those containing St. John's wort.

Therefore, before starting therapy with the drug Dapoxetine, you need to tell your doctor about all the medications you are taking - this will help avoid complications.

Method of taking Dapoxetine

The tablet is intended for oral use. It should be swallowed without chewing and washed down with a full glass of water. As a rule, when first used, it is advisable to take a tablet with a dosage of 30 mg. 1 hour before sexual intercourse. If the effect is weak, next time the dosage can be increased to 60 mg. Dapoxetine can be taken 1 time per day, not more often.

Before using a remedy to treat early ejaculation and prolong sex time, it is advisable to consult a doctor. The course of taking Dapoxetine is usually 1 month or 6 servings. If necessary, the course is repeated. If a man has mild liver and kidney dysfunction, caution must be exercised when consuming Dapoxetine.

Dapoxene - what is it?

The drug belongs to the group of drugs that normalize sexual function. At the same time, it does not excite the penis, like the well-known Viagra, but controls ejaculation, that is, prevents the rapid completion of sexual intercourse. Dapoxetine (English – Dapoxetine) today is not prohibited in Russia, as it is written on many Internet resources. The drug can be purchased not only via the Internet, but also in pharmacy chains in the Russian Federation.

Side effects of the medicine

During scientific experiments, the following frequently occurring negative reactions of the body were identified:

1. nausea (11% when using 30 mg and 22% when using 60 mg of Dapoxetine);
2. dizziness (5.7 and 10.8%);
3. headache (5.5 and 8.7%);
4. diarrhea (3.4 and 6.8%);
5. insomnia (2.2 and 3.8%);
6. fatigue (2 and 4%).

Most often, refusal to take Dapoxetine was caused by nausea (2% of patients) and dizziness (1.2%). Below is a comparative table of all the side effects that appear after taking the medicine.

The drug "Dapoxetine": reviews from doctors

In fact, such products are extremely popular. For example, in Europe and the United States of America, the serotonin inhibitor was officially introduced into medical use in 2004. Today, many domestic experts recommend taking the drug Dapoxetine. Reviews from doctors, as well as patients, confirm the effectiveness of this medicine, which actually increases the duration of sexual intercourse several times. As for the disadvantages, they include, first of all, the high price. In addition, approximately 20% of patients experience some side effects. But in any case, you need to remember that premature ejaculation can be the result of exposure to a host of external and internal environmental factors, so you should first identify and eliminate the cause of problems with sexual activity.

Contraindications to the use of Dapoxetine

• Hypersensitivity of the body to any ingredient of the drug;
• diseases of the cardiovascular system;
• priapism;
• anatomical curvature of the genital organ;
• mental disorders;
• severe diseases of the digestive system;
• oncological diseases;
• severe disorders of the liver and kidneys;
• allergy to lactose.

Also, the drug for the treatment of early ejaculation cannot be combined with the following drugs:

• monoamine oxidase inhibitors (Nialamide, Iproniazid, Tranylcypromine, Befol, Garmalin, Pirlindol). They should not be taken within 7 days after the last use of Dapoxetine;
• drugs with serotonergic effects (Tramadol, Lithium, Linezolid, Tryptophan, drugs based on St. John's wort);
• CYP3A4 inhibitors (Ritonavir, Ketoconazole, Atazanavir, Telithromycin, Nefazodone, Nelfinavir, Itraconazole, Saquinavir);
• medications that affect platelet adhesion (Aspirin, Dipyridamole, Tiklid, Pentoxifylline);
• Thioridazine;
• Warfarin;
• antidepressants.

Dapoxetine is not intended for women or men under 18 years of age.

Analogues of the drug

If necessary, the attending physician may recommend to the patient the use of analogues and generics of Dapoxetine, which have a similar therapeutic effect on the body.

Substitutes for the drug are:

1. Cialis is a drug. Containing tadalafil as an active ingredient. The product improves erectile function. The drug is available with a prescription. The shelf life of the medicine is 3 years. Tablets should be stored at a temperature not exceeding 30 degrees in a place that is inaccessible to children. The cost of the drug is 980 rubles per package.
2. Sildenafil is a drug containing sildenafil citrate as an active ingredient. The medicine is produced in the form of film-coated tablets, which are packaged in blisters of 1 and 4 tablets. The medication provides increased potency. The drug is dispensed in a pharmacy according to a prescription. The drug should be stored in a dry place at a temperature not exceeding 25-30 degrees. Celsius. The shelf life of Sildenafil is 2 years. The cost of the medicine is from 980 to 3000 rubles.
3. Speman is a medicine developed on the basis of natural plant materials. The medicine reduces urinary disorders and stagnation in the case of benign prostatic hyperplasia and stimulates spermatogenesis. The product is sold without a prescription. The shelf life is 3 years at an ambient temperature of 10 to 30 degrees Celsius. The price of the medicine is 230-300 rubles.

Poxet, Viagra, Pi Force, Livitra and some others can be used as substitutes.

Also, the attending physician may recommend the use of Russian analogues of Dapoxetine. One of the most common medications is Primaxetine.

Tips for using Dapoxetine

• Before taking it, you need to make sure that you are not dehydrated. This is especially important for men who have not drunk liquid for the last 5-6 hours. It is also advisable to make sure that there is no sweating and illnesses that are accompanied by vomiting, diarrhea or body heat;
• Take the tablet with a full glass of water;
• alcohol should not be taken under any circumstances - this will significantly increase the side effects;
• after taking Dapoxetine, you need to get up slowly, slowly;
• Dapoxetine hydrochloride affects the ability to drive vehicles. Therefore, you should not drive or perform actions that require increased concentration.

Dapoxetine - harm of the drug to the body

Various clinical studies have shown that the drug is well tolerated by most men. As for harm to health, it manifests itself only in the form of side effects of varying severity. Dapoxetine may cause harm in the following cases:

1. A drug of poor quality was purchased. In this case, the side effects will be severe. If a man takes such Dapoxetine, he needs to seek medical help as soon as possible;
2. if a man ignored the prohibitions on using Dapoxetine. Therefore, you need to carefully study the instructions for the drug to know what side effects and contraindications it has. In general, it is advisable to consult a doctor before using Dapoxetine;
3. Harm from Dapoxetine may occur if it was taken simultaneously with certain medications.

Indications for the use of a tonic drug

It is recommended to take the stimulant no more than once a day in case of severe problems with the formation of an erection. Urologists prescribe a course of medication if they detect decreased sexual activity, as well as a weak and short-lived erection, which ends after premature ejaculation and does not allow partners to receive complete satisfaction. Ejaculation can occur after minimal sexual stimulation, shortly after sexual penetration, or before intimacy begins. The presence of early ejaculation negatively affects a man's emotional or sexual well-being. Many patients with low resistance to stress develop psychogenic disorders, experience severe depression, and lose self-confidence. All the described changes in the emotional background entail a decrease in sexual potency and the desire to avoid any close contact with the opposite sex. The basis for undergoing drug treatment may be a weakening of control over the processes of ejaculation. Urologists associate this pathology with low levels of serotonin in the synaptic space.

What is Dapoxetine?

This is a drug from the group of selective serotonin reuptake inhibitors (abbreviated as SSRIs). Interesting fact: Dapoxetine was first developed as an antidepressant. But during clinical studies, experts found that the medicine has the ability to delay the onset of orgasm.

The main component of Dapoxetine is a substance called dapoxetine hydrochloride. It is thanks to him that you can have sex 3-4 times longer. Dapoxetine hydrochloride blocks the reuptake of serotonin, after which the sensitivity of the head of the penis weakens.

Dapoxetine is available in the form of tablets of various dosages - 30, 60 and 90 mg. The tablet must be swallowed and washed down with water one and a half hours before sexual intercourse. The duration of action of dapoxetine hydrochloride is 6 hours, and 3 hours after administration the drug has the greatest effect.