Dicynone is a hemostatic drug that has been used for quite a long time to stop bleeding, an ambulance for bleeding of various types and origins.
The drug is presented both in tablet format and in solution for injection and the active ingredient in it is ethamsylate.
The very effect of the active substance of the drug is aimed at:
- Increases blood clotting and blood clot formation by stimulating bone marrow functions in the body.
- Due to the formed blood clots, it gives a hemostatic effect.
- Strengthens the walls of blood vessels and their elasticity, helps normalize the circulation of fluid between tissues and vessels.
All this makes it possible to use the drug during periods when there are heavy menstruation.
Pharmacodynamics and pharmacokinetics
The medication stimulates the process of platelet release from the bone marrow and enhances their formation. The drug has antiplatelet and angioprotective effects. The drug helps stop bleeding, increases the rate of formation of the primary thrombus , etamsylate enhances retraction, has no effect on prothrombin time , fibrinogen concentration. With repeated use of the drug, thrombus formation increases. Dicynone reduces diapedesis of formed and blood elements from the vascular bed, reduces fluid output, and has a positive effect on microcirculation . The drug does not affect the normal indicators and parameters of the hemostasis system. Dicynone is able to restore altered bleeding time in various diseases.
The hemostatic effect is felt after 10-15 minutes. The peak level of the active substance is reached an hour after administration. It is excreted unchanged on the first day almost entirely in the urine.
pharmachologic effect
The active ingredient of Dicynone is ethamsylate.
The drug has a hemostatic effect (stops or reduces bleeding), which is due to the ability of the drug to activate the formation of thromboplastin (formed at the initial stages of the coagulation process) when small vessels are damaged.
The use of Dicynone allows you to increase the formation of large masses of mucopolysaccharides (protect protein fibers from injury) in the walls of capillaries, normalize capillary permeability, increase their stability, and improve microcirculation.
Dicinone does not have the ability to increase blood clotting and cause vasoconstriction, and does not contribute to the formation of blood clots. Dicynone begins to act 1-2 hours after oral administration and 5-15 minutes after injection. The therapeutic effect of Dicynon is observed within 4-6 hours.
Indications for use of Dicinone
What is Dicynon in tablets and ampoules for?
The medicine is prescribed to stop bleeding and prevent it: capillary, parenchymal bleeding (postoperative, traumatic, after dental interventions, intestinal, renal, pulmonary bleeding). The drug is prescribed for secondary bleeding due to thrombocytopathy , thromphocytopenia, hematuria, hypocoagulation, intracranial hemorrhage, hemorrhagic vasculitis , drug-induced bleeding, hemorrhagic diathesis .
Indications for the use of Dicinon are repeated retinal hemorrhages, diabetic retinopathy, Werlhof's disease. Dicinone for menstruation is prescribed for heavy menstruation.
Basic measures
You can try and increase the level of platelets in your blood at home. To do this you need:
- Change your diet. The composition of the blood greatly depends on nutrition, for this reason it is worth eating foods with a high amount of iron, as well as plant foods.
- Fatty and spicy foods are prohibited. A person suffering from thrombocytopenia should reduce the amount of fatty broths, sausages, smoked meats, and fast food in their diet. It’s better to completely give up such food for a while, until the number of blood cells begins to increase.
- Consult a doctor who will prescribe medications to increase platelet counts in the blood. This measure is necessary if it was not possible to quickly raise platelet levels with the help of a proper diet.
Any medications must be prescribed by a doctor; relying on self-medication is very dangerous.
Instructions for use of Dicinone (Method and dosage)
The medicine is taken orally, administered intramuscularly, intravenously. In ophthalmology it is used retrobulbarly. Single dose – 0.5 grams (tablets), 0.25 grams (parenteral). To prevent bleeding during surgical interventions, Etamzilat is administered one hour before surgery. Dicynone for menstruation, pulmonary, intestinal bleeding: 0.5 grams daily, course of treatment for 5-10 days. For diseases of the blood system, hemorrhagic diathesis, diabetic angiopathy, take 0.75 grams, duration of therapy is up to two weeks. To prevent postoperative bleeding, Dicynon is taken in an amount of 8 mg/kg.
Hemorrhagic syndrome: three times a day, 6-8 mg/kg, duration of administration up to two weeks, if necessary, repeat the course after a week.
Diabetic microangiopathy (hemorrhages): intramuscularly 0.25 grams three times a day, injections are given for 3 months. A sterile swab soaked in ethamsylate can be applied to the wound surface to stop bleeding.
Dicinon tablets, instructions for use
Usually take about 15 mg/kg per day. That is, 1-2 tablets at a time, 3 times every 24 hours.
Children aged three to twelve years take half the adult dose.
Dicinon injections, instructions for use
Dicynon is administered intravenously or intramuscularly. Usually 1-2 ampoules 3 times a day.
Instructions for use of Dicinon during menstruation
Used only with the permission of the attending physician. For heavy periods, 2 tablets are prescribed 3 times a day 3-5 days before menstruation and for five days after their onset. It is recommended to repeat the course at the next menstruation to consolidate.
It is not recommended to use the drug to stop menstruation.
How to take Dicinon for uterine bleeding
Only under the supervision of a doctor. For uterine bleeding, it is recommended to take Dicinon by injection, 1-2 ampoules every 6 hours until the bleeding stops or the risk of its recurrence disappears.
How to increase during pregnancy
During the period of bearing a child, a woman regularly undergoes a blood test for clotting. Indeed, in the first half of pregnancy there is a risk of miscarriage, in the second - premature birth, and during the birth itself - heavy bleeding.
The cause of a low number of platelets in the blood is often early gestosis. In the case of such a disease in a pregnant woman, the placenta produces substances that increase vascular permeability, i.e., fluid gradually leaves the blood.
Externally, platelet deficiency manifests itself as follows:
- severe swelling;
- kidney dysfunction;
- increased blood pressure;
- an attack of eclampsia with convulsions or cerebral hemorrhage (as the most severe consequence).
How to increase platelets in the blood during pregnancy?
- eliminate the underlying pathology (the cause of low levels of blood platelets);
- discontinue medications that have side effects on the blood;
- take care of a diet with sufficient vitamins and protein, excluding foods that can cause allergies (preservatives, dietary supplements, etc.);
- corticosteroid hormones and immunoglobulin, Interferon, Vitamin B12 in injections and folic acid in tablets are prescribed medicinally; for hemorrhages - epsilon-aminocaproic acid orally and locally;
- in case of blood diseases, an operation is often performed to remove the spleen and give a platelet transfusion.
The criticality of the drop in platelet levels relative to the norm is determined by the doctor.
It is he who decides which treatment method to prefer and what can be done. Many people in the question of how to increase platelets in the blood were saved by even the most common diet recommended in terms of vitamin composition. Monitor your health and respond to all changes in it in a timely manner!
It is possible both with the help of pharmaceutical drugs and using folk remedies. It is worth noting that such colorless and small bodies circulate in huge quantities in human blood and are responsible for its ability to clot. The normal number of platelets is considered to be between 180 and 320 thousand. If this volume is significantly exceeded, blood clots can very quickly form in the vessels, which will ultimately cause a heart attack or stroke. If, on the contrary, there is a deficiency of these bodies, then the person gets thrombocytopenia or thrombocytopathy, as well as a large number of unpleasant diseases.
If you are faced with the above problem, then you will probably be interested in the question of how to increase platelets in the blood. Unfortunately, not every specialist will be able to give you useful advice on this matter. In this regard, it is better to independently monitor your own health, and especially your diet.
Like in the blood using pharmaceutical drugs
Currently, pharmaceutical companies produce quite a lot of different medicines that quickly and effectively solve this problem. However, it is worth noting that these tablets and vitamins should be purchased only after consultation with your doctor. After all, almost all of them have their contraindications and side effects.
You can increase platelets in the blood with the help of a drug such as Sodecor. It is this remedy that doctors most often prescribe to their patients, as it contains a mixture of various herbs and spices that help solve the problem.
How to increase platelets with folk remedies
Before using pharmaceutical medications to eliminate such an ailment, many people try to increase platelet levels using folk remedies. After all, such methods are much safer and much cheaper.
The ideal solution for normalizing platelets in the blood is a properly selected diet that includes foods that contain a lot of iron. By consuming such ingredients, a person can not only recover from thrombocytopenia, but also at the same time protect his body from anemia and other troubles.
Let's list the most useful foods that increase platelets in the blood.
- beef liver;
- hazelnut;
- pomegranate;
- buckwheat porridge;
- bananas;
- peas;
- beef;
- melon, etc.
2. Products that thicken the blood, accelerate its clotting and increase platelet content:
- beet;
- fish;
- fresh nettle leaves;
- sugar;
- parsley dill;
- green tea, etc.
In addition, to increase your platelet count, you should be sure to limit your intake of blood thinning ingredients. These include ginger, chocolate, raspberries, olive oil, blueberries and dried nettle leaves. In addition, a person with a diagnosis of thrombocytopenia will have to say goodbye to anticoagulant drugs (i.e. acetylsalicylic acid or aspirin), ointments that contain heparin, as well as decongestant gels.
Abnormalities in blood test results are the first signal of possible disturbances in the functioning of the body or the development of serious diseases. A low platelet level is especially dangerous because the blood loses its ability to clot quickly in the event of injury. Even minor tissue damage can lead to heavy bleeding. In this case, the doctor will prescribe appropriate treatment and tell you how to increase platelets in the blood quickly.
Dicynon's analogs
Level 4 ATC code matches:
Water pepper extract
Etamzilat
The main analogue is a drug that has the same name as the main active ingredient - Etamzilat .
Which is better: Dicynon or Tranexam?
Tranexam is considered a more effective drug for stopping bleeding.
Vitamins
Of course, before making an independent decision to use any vitamin complexes, it is necessary to find out the reason for the decrease in platelets in the blood. After all, for example, a lack of a vitamin such as B 12 may be one of these reasons. And then it is precisely its lack that will need to be filled.
Increasing the level of platelets in the blood without taking various vitamin complexes, i.e. naturally, is extremely difficult and time-consuming. An integrated approach (diet and vitamins) will bear fruit much faster.
In first place in terms of speed and quality of absorption is vitamin C. Since it is soluble in water and can be instantly absorbed into the body, this vitamin quickly strengthens the immune system and normalizes platelet production.
The doctor will advise which vitamin complex to choose (depending on the cause of your disease, the stage of its progression and the individual characteristics of the body). In pharmacies, vitamins are sold in a large assortment and without a prescription.
Reviews of Dicynon
Reviews of Dicinone in tablets and ampoules indicate that the drug is a very effective remedy for stopping bleeding. It tastes bitter.
Reviews for menstruation
They perfectly help with heavy menstruation, for which they are often taken.
Reviews during pregnancy
Recommended with caution, but generally no side effects have been reported. Expectant mothers take this drug, pregnancy is successful.
For uterine bleeding
Used under the supervision of a physician. Helps stop uterine bleeding. However, the effect may not last long.
Contraindications
In accordance with the instructions for Dicinon, the use of the drug is contraindicated if the patient has:
- Neoplastic (tumor) diseases of lymphatic and hematopoietic tissues, including osteosarcoma, myeloblastic and lymphoblastic leukemia;
- Thrombosis;
- Acute porphyria;
- Thromboembolism;
- Hypersensitivity to the components of the tablets/solution.
Dicinon is used with caution to treat patients with a history of thrombosis or thromboembolism, as well as in cases where the cause of bleeding is an overdose of anticoagulants.
Dicinon price, where to buy
The price of Dicinon in tablets is approximately 380 rubles per package of 100 pieces. How much do tablets cost in Ukraine? You can buy a package for 320-340 UAH.
The price of Dicinon ampoules is 530 rubles for 50 pieces. The cost in Ukraine is 350-380 UAH.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Dicynone tablets 250 mg 100 pcs. Lek dd
RUB 342 order
Pharmacy Dialogue
- Dicynon (tab. 250 mg No. 10)Lek
44 RUR order
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Pharmacy24
- Dicynon 250 mg 2 ml No. 50 injection solution Lek pharmaceutical company d.d., Slovenia
435 UAH.order - Dicynon 250 mg No. 100 tablets Lek pharmaceutical company d.d., Slovenia
379 UAH. order
PaniPharmacy
- Dicynone tablets Dicynone tablets 250 mg No. 100 Slovenia, Lek
408 UAH. order
- Dicinone ampoule Dicinone solution d/in. 250mg amp. 2ml No. 50 Slovenia, Lek
414 UAH order
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Therapeutic diet
When patients wonder how to increase platelet levels in the blood, they often hear about dietary adjustments. This is truly the simplest and most harmless way to treat thrombocytopenia. However, it should be remembered that a therapeutic diet has an increasing effect on the platelet count only in the initial stage of the disease, when the deviations are not critical.
In serious cases, special nutrition will not be enough and medications are used for treatment.
First of all, in order to increase the level of platelets in the blood, it is recommended to exclude foods that negatively affect the process of hematopoiesis and thin the blood (ginger, olive oil, etc.). Alcohol and any dishes and cocktails containing it are completely excluded. Also prohibited are high-calorie foods, fried and deep-fried foods, street fast food, etc.
The main product that increases the number of platelets and other blood cells is meat. It is better to give preference to beef, that is, red meat, but do not forget about turkey, chicken and rabbit meat. During treatment, doctors recommend that vegetarians deviate from the principles and include a sufficient amount of meat and other animal foods in their diet to maintain health. Patients who are fasting should also stop limiting themselves to animal foods.
The patient's diet to increase platelet levels should include:
- Meat, offal
- Sea fish, seafood
- Chicken and quail eggs
- Buckwheat and rice cereals
- Legumes (beans, peas, lentils, etc.)
- Nuts, especially walnuts and hazelnuts
- Pumpkin, beets, melons, pomegranate seeds
- Fresh herbs (parsley, dill, etc.)
- Green tea
- Mineral water without gas (at least 1.8 liters)
Doctors recommend supplementing treatment with proper nutrition and including healthy plant foods in the diet, especially foods rich in iron and vitamins A, B12 and C. You should maximize your consumption of fresh vegetables and fruits, as well as fresh juices and smoothies made from them. However, packaged juices and nectars are strictly prohibited. It is also not recommended to use semi-finished products and ready-made industrial sauces (mayonnaise, ketchup, dumplings, etc.). Only fresh food can increase the platelet count, while semi-finished products rich in food and flavor additives have a depressing effect on the body's systems.
Drug interactions
When taking Dicynone with other medications, you should be careful, checking the instructions. Below is a list of such interactions:
- administration of Dicynone after the administration of dextrans does not have a hemostatic effect, but before it prevents the antiplatelet effect;
- combination with aminocaproic acid, sodium menadione bisulfite is allowed;
- incompatible in a syringe with other medications, sodium bicarbonate and lactate solution for injections, saline;
- combination with anticoagulants is prohibited;
- combination with Tranexam threatens to activate platelet formation processes.
Side effects
Using the drug in the form of a solution does not always bring positive results. Side effects often occur in children and adults due to Dicynon. The list of the most common unwanted consequences includes:
- heaviness in the epigastric region;
- nausea;
- skin rash;
- headache;
- increased fatigue.
A little less frequently, side effects from Dicynon occur, such as facial skin flushing, dizziness, thrombocytopenia, neutropenia, agranulocytosis, arthralgia, fever, paresthesia of the lower extremities, allergic reactions. Particular attention should be paid to the last undesirable effect. Allergic reactions can be provoked not only by the active substance of the drug, but also by the auxiliary components. For example, sodium sulfite can cause nausea, diarrhea, asthma attacks, anaphylactic shock, manifested by generalized itching, difficulty breathing, hypoxia, and convulsions. In case of side effects, "Ditsinon" is cancelled.
There is another undesirable consequence. When administered parenterally, the drug can significantly reduce blood pressure. This must be taken into account when treating patients suffering from hypotension.