Donormil is prescribed to restore sleep. This is a drug with sleeping pills and sedative properties. Normalizes the structure and duration of sleep without disturbing the phases. It acts for several hours after ingestion. Prescribed to patients over fifteen years of age. Use is possible only under the supervision of a physician.
The drug was originally developed to eliminate allergic reactions. Later, the sedative properties of this chemical compound were discovered. This is the first antihistamine that began to be used to normalize sleep.
Indications for use
Instructions for use for the drug Donormil indicate that the drug is prescribed for sleep disorders.
This can be either restless sleep (with nightmares), or insomnia and prolonged falling asleep.
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Overdose
Each person has his own metabolism, so for one patient ½ Donormil tablets will have the desired effect, but for another, even two tablets will not help. It is necessary to carefully monitor the body’s reactions to the use of Donormil, follow the instructions, otherwise, in case of an overdose, the following symptoms are possible:
- constant drowsiness, absent-mindedness, followed by attacks of an overexcited state;
- increased likelihood of apnea;
- tachycardia, arrhythmia;
- febrile state, elevated temperature;
- convulsions, hallucinations, loss of consciousness, death.
Contraindications
The sleeping pill Donormil has many contraindications:
- if the patient has a disease of the urethra or prostate gland (exacerbates difficulty urinating);
- children under 15 years of age;
- lactation period and pregnancy (the ability to penetrate through the blood and affect the fetus);
- if an allergic reaction to the components of the drug is detected.
The use of the drug is not recommended if there is impaired liver or kidney function. If prescribed, under the supervision of the attending physician.
Instructions for use
Let's study in more detail the instructions for use for the sleeping pill Donormil.
Mode of application
Donormil is taken orally:
- If the drug is made in the form of an effervescent tablet, it is dissolved in water. (1 tablet per 100 ml of water is recommended).
- If it is a film-coated tablet, take it with water (a small amount).
If there is no improvement, the doctor may prescribe the drug in a dose of two tablets, and if after 5 days of taking this medicine there is no improvement, it should be replaced with another (selected and prescribed by the doctor).
Release forms
Available in two types of tablets:
- effervescent (dissolves in water);
- coated pills.
Dosages
Prescribed half or one tablet before bedtime. If the result is minimal, the doctor increases the dose to 2 tablets. If side effects are detected, use of the drug is discontinued.
Morning sleepiness
Some people experience after-effects of Donormil: difficult awakenings, morning drowsiness, disorientation and lack of coordination in the first hours after getting out of bed.
These problems can be dealt with in several directions:
Increase sleep duration. Carefully calculate the time of taking the drug so that you begin to engage in conscious activities no earlier than 7-8 hours after taking the pill.
Reduce the dose of the drug in the hope that the therapeutic effect will remain and the side effects will go away.
Simply avoid complex activities that require attention in the morning.
Consult your doctor and change the drug.
Side effects and special instructions
Side effects
Taking the drug may be accompanied by side effects:
- drowsiness (during the daytime);
- ear in the mouth (small salivation);
- difficulty urinating, constipation.
All of the above symptoms disappear after stopping the use of the drug.
special instructions
The drug should not be taken while driving.
The hypnotic effect can lead to a slowdown in reaction speed, concentration, the driver falling asleep at the wheel and, as a consequence, to an accident and a disastrous result.
It should be prescribed with caution to people in the older age group (over 65 years old), due to possible dizziness.
Interactions with other drugs
should be used with caution with:
- medications of groups affecting urination;
- antidepressants;
- with alcohol and medications containing it.
Reviews from patients who took Donormil and alcohol indicate that it is not recommended to use Donormil with alcohol and substances containing it.
The hypnotic effect is enhanced, consciousness is suppressed and relaxation is enhanced. An overdose and poisoning of the body may
Use during pregnancy and lactation
There are no exact descriptions that have been studied, but there are suggestions that the drug is able to penetrate into the mother’s breast milk inside the body and affect the fetus during pregnancy.
It is not prescribed during pregnancy and lactation; if such a need is present, it is prescribed under the supervision of a doctor.
Is the drug prescribed for children?
The use of Donormil is contraindicated for children under 15 years of age.
Interaction
In the case of simultaneous use of Donormil with other sedatives, barbiturates , anxiolytics , antipsychotics , central antihypertensive drugs , baclofen , thalidomod , pizotifen , the effect on the central nervous system (CNS) increases. In the case of simultaneous use of the drug with m-anticholinergic drugs ( antiparkinsonian drugs , atropine , disopyramide , imipramine antidepressants , etc.), side effects such as constipation , urinary retention and dry mouth .
Reviews from patients and doctors
Having studied the reviews about the sleeping pill Donormil, the following positive points can be noted:
- many observe its effect after stopping use of the drug;
- comparing it with previously used ones, they note the absence of negative effects on the body;
- Doctors agree that this drug is newer and more modern, having a mild effect on the patient’s body.
Reviews from doctors
Here's what doctors say :
- “Very often, when a patient comes to me, he does not go into detail about his deviation from normal sleep. There are cases where the cause may be constant, systematic falling asleep while watching the TV. In this case, I advise you to take Donormil (half a tablet, before bed) - a medicine that, unlike many sleeping pills, cannot have a negative effect on the body (addiction and the inability to fall asleep without it)" (Sergeev I.O.) .
- “This drug should be prescribed only for severe sleep disorders. It should be used with caution when treating elderly patients” (Romanova A.R.).
Patient reviews
Patient reviews about Donormil tablets are as follows :
- When the doctor prescribed Donormil to me (I am 72 years old and had previously used other sleeping pills), I doubted its effect, citing the fact that the young specialist was promoting the drug. But after taking it, already on the 3rd day my sleep returned to normal. I didn't wake up in the middle of the night. The only thing is, after an unplanned awakening (noise from outside), I could not sleep for a long time” (Valentina).
- “At about the age of 16, I began to systematically drink alcohol. From the age of 20, I began to drink daily, at least 0.5 liters of vodka per day. At the same time, albeit irregularly, I started smoking marijuana. In general, by the age of 27, I turned into a complete alcoholic and drug addict, because in addition to everything I learned to independently isolate methamphetamine - pervitin - from freely available drugs and use it intravenously. I don’t know how, but under the pressure of personal life circumstances, I decided to give up all types of doping. Immediately after stopping taking drugs and alcohol, I began to experience severe sleep and mood disturbances, not to mention digestion and appetite. A narcologist I know advised me to take Donormil, saying that in my case it is the optimal sedative with a minimum of side effects and harm to the body. Already in the first days of taking Donormil, my sleep and appetite began to normalize. After two weeks of taking it, I completely forgot about withdrawal. Now I’m 30 years old, my health and sleep have returned to normal, which I largely owe to the drug Donormil” (Peter, Belgorod).
Advice from patients
Things to consider:
- “If your doctor has prescribed this medicine to you, do not be afraid to use it. It helps you fall asleep within 15 minutes. The only thing is, don’t overdo it with the dose and try to find out the cause of the sleep disorder” (Roman).
- “I advise you to use it no earlier than 20 minutes before your intended night’s rest, otherwise you will not be able to complete your planned activities for the evening” (Valentina).
Absorption and excretion
After oral administration, the special coating of the tablet form dissolves in the intestines. The drug is well absorbed in the gastrointestinal tract. The active component penetrates the bloodstream and acts on cellular receptors. The maximum level of the substance in the blood occurs approximately 120 minutes after administration. The chemical compound overcomes biological barriers. Penetration through the blood-brain barrier allows the substance to enter the brain and cause a therapeutic effect.
Appointed by a specialist
The half-life is ten hours. The substance is modified in the liver tissue and is primarily excreted from the body in the urine. It is also partially excreted through the digestive tract. In elderly patients and people suffering from kidney or liver problems, the half-life is prolonged. With a new course of use, a constant level of the substance and its derivatives in the blood appears later and at an increased level.
Pros and cons of using the drug
When studying the effects of the drug, the advantages include :
- lack of habituation of the body;
- fast action;
- after discontinuation of use, continuation of action.
The disadvantages include:
- with an unplanned awakening, inability to fall asleep immediately;
- in case of overdose, temporary impairment of visual acuity;
- increased heart rate;
- increase in body temperature.
The conclusion may be that if you do not overdo it with the use of the drug, then no side effects should occur.
Visual impairment
Most often this manifests itself as blurred vision. You have to strain your eyes, especially when working with documents and small objects. Sometimes dry eyes appear, which is especially unpleasant for people whose profession involves using a computer.
If you read reviews about the side effects of Donormil, two things become clear. First, such a reaction can occur both at the beginning of treatment and after some time. Secondly, as a rule, it does not go away on its own. In case of significant visual impairment, you should stop taking sleeping pills.
Forms of release and cost
The drug is available in the form of tablets: effervescent (they have a cylindrical shape, flat, beveled edges. There is a notch on one side of the tablet).
The drug is produced in France. Donormil price - 234 rubles.
Available in a cardboard box, 2 tubes (each tube contains 10 pieces, each containing 15 mg).
Film-coated tablets (rectangular, white, scored on both sides).
Available in cardboard packaging, 2 tubes (each tube contains 10 or 30 pieces of 15 mg each)
Cost depending on the country of manufacture and package size:
- price for sleeping pills Donormil (Germany) 10 pcs.: - 135 rub.
- Domormil tablets (France) 10 pcs.: - 235 rub.
- price 30 pcs.: — (France) — 250 rub.
Price
You can buy Donormil in regular pharmacies, but many people prefer to buy Donormil in an online store from a catalog and order delivery due to its low cost. The approximate price for Donormil in Moscow pharmacies is shown in the table below:
| Pharmacy name and address | Price per package of Donormil of 30 tablets (rubles) |
| Pharmacies Stolichki, metro Proletarskaya, stop. Railroad crossing | 303 |
| Economy in Khovrino, st. Petrozavodskaya, 9, building 2 | 312 |
| 1st pharmacy, 1st Botkinsky lane, 2/b | 327 |
Analogues of the drug
Analogs of Donormil include substances that have an identical composition of active ingredients and release form.
There are a lot of them.
There are several commonly used and well-known ones.
Valerian
Valerian or its extract (cost about 20 rubles):
- has a sedative effect;
- the result comes progressively after 3-4 weeks of use.
Persen
Another analogue of Donormila Persen (price about 250 rubles):
- the relaxing effect occurs in a short time;
- works as long as it is used.
Sedasen
Sedasen (price about 130 rubles):
- can be used for one-time use;
- does not have a long-lasting effect.
At the same time, Donormil is very popular among patients suffering from sleep disorders .
It is also often prescribed by therapists, as it has minor contraindications and virtually no side effects. However, you should not self-medicate and take medicine without medical advice.
Each case of sleep disturbance and other behavioral disorders is highly individual and requires personal study by an appropriate medical specialist.
Self-administration and dosage adjustment of Donormil and other sedative medications may lead to undesirable health consequences . Before prescribing, be sure to consult with your doctor.
Action of Donormil
According to the classification, the active substance belongs to H1-antihistamines, hypnotics and sedatives. In the human body, the chemical compound acts on special cellular receptors, thereby blocking the mediator acetylcholine. A cholinolytic effect develops. The drug reduces the duration of falling asleep and increases the duration of night rest. At the same time, there is no common side effect of sleeping pills, which is disruption of sleep phases. The medicine exhibits its activity within six to eight hours.
Due to its action, the active component is also considered an antiallergic agent. The therapeutic effect eliminates the inflammatory process, disrupting the production of inflammatory mediators in tissues. Other manufacturers make doxylamine for the symptomatic treatment of cough, skin rashes, itching and other allergic manifestations.
