The life of a modern person is associated with instability of the emotional state. Against the background of stress, general health worsens and the risk of developing various diseases increases. Russian scientists have created a drug that helps maintain balance in any situation. "Tryptophan Calm Formula" from "Evalar" guarantees a positive attitude and good performance during the day and a restful sleep at night.
Release form and composition
Dosage form - capsules: weighing 0.275 g, gelatin, with a white body and cap (60 pieces in a jar or 15 pieces in a blister, in a cardboard pack 1 jar or 1 blister and instructions for use of Tryptophan Calm Formula).
1 capsule contains:
- active ingredients: L-tryptophan - not less than 250 mg, calcium pantothenate - not less than 2.5 mg, pyridoxine hydrochloride - not less than 1 mg;
- auxiliary components: gelatin, titanium dioxide (dye), magnesium stearate (anti-caking agent).
Side effects
Judging by the reviews, Tryptophan from Evalar is well tolerated by most people. In addition, it does not work the next day after the evening dose.
Side effects from using Tryptophan from Evalar are extremely rare. In isolated cases the following are observed:
- dry mouth;
- loss of appetite;
- drowsiness.
If the doctor has additionally prescribed antidepressants, simultaneous use of the drugs can trigger the occurrence of serotonin syndrome, which disappears soon after.
Pharmacological properties
Pharmacodynamics
Calm Formula Tryptophan is a dietary supplement that promotes the synthesis of serotonin and melatonin in the body, supports the normal sleep-wake cycle, and also has an adaptive effect when changing time zones (for example, when traveling).
Properties of the active components of the Calm Formula Tryptophan:
- L-tryptophan is an important amino acid, without which the body cannot produce serotonin, which affects good mood, emotional comfort, feelings of joy and happiness. It increases mental performance, cognitive activity and self-esteem, as well as stress resistance. Improves physical performance, increases the body's endurance and strength. After the onset of darkness, serotonin is converted into melatonin, which is a physiological regulator of sleep, i.e. it improves the process of falling asleep, regulates the duration of phases and quality of sleep;
- Pantothenic acid is considered an anti-stress vitamin. In case of pantothenic acid deficiency in the body, sleep disorders, increased fatigue, irritability and fatigue are observed;
- pyridoxine (vitamin B6) is necessary for the normal functioning of the central and peripheral nervous system, participates in the metabolism of tryptophan and the synthesis of serotonin.
Thus, during the daytime, Calm Formula Tryptophan enhances the natural production of serotonin, the so-called happiness hormone, and thereby improves mood, improves mental comfort, eliminates depression and emotional stress, reduces anxiety, aggressiveness and irritability, and increases performance.
At night, the dietary supplement helps the natural production of melatonin, the so-called sleep hormone, and thereby improves the process of falling asleep, the quality and depth of sleep, eliminates the problems of interrupted sleep, i.e., allows you to get enough sleep and rest in a short time.
Pharmacokinetics
Information is absent.
Indications
The body of every person contains an amino acid that plays an important role in the synthesis of proteins and antibodies of the defense system. It's called tryptophan. With a sufficient amount of it, a high level of stress resistance is maintained, fatigue does not bother you, and the organs of the gastrointestinal tract function well.
Tryptophan enters the body with food containing animal proteins. However, it is not enough to maintain a constant level of amino acid. The process of digestion of such products is associated with the formation of substances that suppress the effect of tryptophan. In order for the body to receive the required amount of amino acids, you need to eat meals containing large amounts of complex carbohydrates. But, as a rule, this is not enough. In such cases, doctors recommend the drug Tryptophan from Evalar. Reviews from people who took it are extremely positive: insomnia, chronic fatigue and constant irritability recede in a short time.
Experts note that it is undesirable to ignore the purpose of the drug. A lack of an important amino acid can lead to serious consequences:
- anemia;
- cataracts and other pathologies of the visual system;
- mental disorders;
- deterioration of the condition of teeth, nails, skin and hair;
- pellagra;
- sleep and appetite disturbances;
- delayed physical development in children.
The main indications of Tryptophan from Evalar are:
- constant feeling of anxiety;
- depression;
- aggressiveness towards others;
- irritability during weight loss;
- frequent mood swings;
- disturbances in the gastrointestinal tract;
- seasonal mental disorders;
- pain;
- premenstrual syndrome;
- insomnia;
- bulimia;
- constant feeling of fatigue;
- migraine;
- panic attacks.
In addition, taking the drug improves the condition of vegetative-vascular dystonia. “Tryptophan” from “Evalar” for VSD reduces the likelihood of exacerbations, in some cases the disease completely recedes.
The list of indications for taking the drug can be expanded; they are determined during an individual consultation with the attending physician.
Reviews of Calm Formula Tryptophan
In positive reviews of the Tryptophan Calm Formula, patients note that taking the dietary supplement normalizes wakefulness and sleep cycles, improves mood, helps control emotions in stressful situations, and eliminates feelings of irritability, anxiety and fear. Additional advantages include the absence of addiction, natural composition, good tolerance of the dietary supplement and its availability in pharmacies. The disadvantages are the relatively high cost, large capsule size (inconvenient to take), long course of use, lack of a cumulative effect.
In negative reports, patients complain either about the lack of positive dynamics while taking a dietary supplement, or about the development of the opposite effect, manifested by a deterioration in mood and the process of falling asleep.
Although this information is not included in the instructions for use of Tryptophan Calm Formula, some patients indicate that this dietary supplement should not be taken for chronic bronchitis and bronchial asthma, as it may worsen symptoms.
Contraindications
The main limitation to taking the drug is individual intolerance to its components.
Constant monitoring by the attending physician is required for persons suffering from:
- bladder cancer;
- diabetes mellitus;
- cataracts;
- chronic disruption of the digestion process.
Also, the instructions for Tryptophan from Evalar indicate that the product may cause drowsiness. People who experience it while taking the drug are not recommended to drive vehicles or work with equipment that is potentially hazardous to health and life.
The drug is prohibited during pregnancy and lactation. This is due to the lack of tests for individuals in these categories.
Overdose
Violating the rules for taking Tryptophan by consuming too large doses of the drug can cause general intoxication of the body, which is accompanied by the following symptoms:
- severe nausea and vomiting;
- increased gas formation;
- diarrhea;
- headache;
- decreased blood pressure;
- dizziness;
- impaired coordination of movements;
- physical weakness and fatigue;
- frequent urge to urinate;
- various types of allergic reactions, most of which are manifested by the appearance of a red rash, hives, swelling and itching of the skin surface.
In case of an overdose of Tryptophan, the patient must be provided with complete rest, put to bed and allowed to drink at least 0.5 liters of warm water, and then induce vomiting.
Before the arrival of doctors, it is recommended to use sorbent preparations. In this case, you can use Activated carbon (give the patient at least 10 tablets), Enterosgel (single dose is 1-2 tablespoons), Atoxil (1 sachet of medicine dissolves in 200 ml of water).
Pharmacokinetics
The pharmacokinetics of the dietary supplement Tryptophan is determined by its chemical composition. The maximum concentration of the active components of the drug is achieved 4 hours after taking the first dose of the dietary supplement.
Provided regular therapy with Tryptophan, the average duration of the therapeutic effect of the capsules is from 8 to 12 hours. Therefore, it is very important that the dietary supplement is taken at the same time of day.
The half-life of the constituent substances of the drug occurs in the liver tissues. About 96% of metabolites are utilized by the kidneys and excreted in the urine.
B vitamins can accumulate in the endocrine glands, which are subsequently used to maintain stable functioning of the endocrine system. The main and auxiliary components of the dietary supplement do not have toxic properties and do not contain genetically modified organisms.
Description
The active component of the dietary supplement is the essential amino acid, L-tryptophan. The human body is not able to synthesize this substance on its own. Tryptophan plays an important role in metabolic processes, maintaining nitrogen balance, as well as transforming one type of energy into another.
A lack of L-tryptophan leads to a lack of vitamin B3 and serotonin, and against the background of magnesium deficiency, the risk of coronary artery spasm increases.
Nicotinic acid, synthesized from L-tryptophan, is an important component for proper energy metabolism. It is also involved in the synthesis of proteins, vitamin B3, serotonin, and melatonin.
This amino acid regulates the functioning of the endocrine system, which prevents the development of anemia, normalizes blood pressure, and is responsible for the production of hemoglobin in the body.
Tryptophan, as a mediator of serotonin, has a powerful antidepressant effect, eliminates anxiety, hyperactivity, obsessive states, and normalizes sleep.
Features of using Tryptophan from Evalar
Despite the fact that the drug in most cases has a beneficial effect on the emotional state, there are cases when its use is undesirable or completely not recommended.
During pregnancy and lactation
Taking the drug is prohibited during pregnancy and breastfeeding.
Taking the drug is prohibited during pregnancy.
Is it possible in childhood
The decision to prescribe this drug to a child should be made by a pediatrician. It is recommended to increase the level of tryptophan in the child's body with the help of foods.
Tryptophan in food
The amount of this vital amino acid for the body can be increased by consuming certain types of foods rich in tryptophan. These include freshly squeezed fruit and vegetable juices, in particular tomato juice, prepared independently. Rich in amino acids:
- linseed oil;
- Cod liver;
- seaweed (kelp, spirulina);
- dairy products: cheeses, yogurt, cottage cheese, sour cream;
- beans;
- dried fruits;
- cabbage: broccoli, Chinese cabbage, white cabbage, cauliflower, kohlrabi;
- fruits: melon, bananas, dates;
- nuts;
- seafood: black and red caviar, squid, mussels, oysters, shrimp.
The amount of Tryptophan can be increased by consuming flaxseed oil.
Effect on concentration
It has been noted that in some cases, taking the drug causes a feeling of drowsiness, so it is not recommended to take it before getting behind the wheel, and for people involved in production that require quick reactions when working with equipment.
Reviews from doctors
Anastasia, psychotherapist: “Fragmented, nervous women with personal problems often come to me. I prescribe Tryptophan for them, and after 2-3 visits I notice positive changes, the patients become calmer, more smiling, many are in a better mood, and their family life is improving.”
Victor, somnologist: “I noticed the positive effect of Tryptophan in the treatment of sleep disorders. This relatively inexpensive product quickly helps normalize the process of falling asleep, sleep becomes long and restful, and in the morning patients feel rested and ready for productive work.”
How to use?
According to the instructions, Tryptophan from Evalar should be consumed half an hour before the intended meal. It is advisable to take the drug with a sufficient amount of still water, or, in its absence, juice. It is prohibited to use milk and other products containing animal protein for this purpose.
Regarding the dosage, it is determined by the attending physician on an individual basis, taking into account the general state of health and the use of other medications. As a rule, it does not exceed 2 capsules per day.
The product is not addictive. If necessary, you can take several courses throughout the year.
Storage conditions and periods
The drug should be stored in a dark, well-ventilated room at a temperature not exceeding 25°C. Access to children must be prohibited.
The drug should be stored in a dark, well-ventilated room at a temperature not exceeding 25°C.
Analogs
Several products containing the necessary amino acid are sold on the pharmaceutical market:
- "L-tryptophan." The manufacturer is the American company Now Foods. The average price of the drug in the Russian Federation is 1,300 rubles. for 120 capsules. This product is considered the most popular analogue of Tryptophan from Evalar. The drug does not contain GMOs and fully complies with the GMP quality standard. Each batch undergoes a thorough microbiological test before being sent for sale. L-tryptophan helps improve mood, normalize sleep, and strengthen the immune system. According to the instructions, the drug should be taken 2-3 times a day, 1-2 capsules, each containing 500 mg of active ingredient.
- "The best L-tryptophan." Manufactured by Doctor's Best (USA). Average cost – 1,000 rubles. for 90 capsules. This dietary supplement does not contain gluten and GMOs. In addition, the manufacturer focuses on the vegetarian composition of the capsule itself. The drug is manufactured and tested in accordance with JP (Japan) and USP (USA) standards. Indications are: mental disorders of various types, premenstrual syndrome, bulimia, obesity, insomnia, disruptions in the gastrointestinal tract, weakening of defenses. Unless otherwise recommended by your doctor, the product should be taken 1-2 capsules once a day.
- "Vita-Tryptophan". Made in the USA. The average cost in pharmacies in the Russian Federation is 2,700 rubles. for 90 capsules. Due to the high price, the drug is less popular than L-tryptophan. Indications for its use are: depressive states, panic, anxiety, eating disorders, alcohol addiction, emotional instability during weight loss, chronic fatigue, pain syndrome. "Vita-Tryptophan" should be taken 2-3 times a day, 1-2 capsules half an hour before the intended meal.
- "Timogen". The manufacturer is (St. Petersburg). The average price of the drug is 350 rubles. Available in spray form. The main indications for use are acute and chronic diseases, accompanied by a significant weakening of the defenses. In the body, the active substance alpha-glutamyl-tryptophan is broken down into L-glutamic acid and L-tryptophan, due to which metabolic processes are improved and the emotional background is stabilized.
The above products are the most popular analogues of the drug from Evalar. Each of them has a convenient dosage regimen and a low likelihood of side effects. Judging by the cost, the most optimal analogue is “L-tryptophan” from Now Foods.
Reviews, advantages and disadvantages
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Evalar tryptophan calm formula
Average rating: Number of reviews: 0
Based on reviews of Tryptophan from Evalar, the following advantages and disadvantages were identified:
Pros:
- the supplement calms, eliminates nervousness and irritability;
- improves mood, invigorates;
- normalizes sleep.
Minuses:
- there are side effects such as increased depression, drowsiness;
- the sedative effect lasts only during administration; after discontinuation of the drug, all symptoms return.
To avoid side effects, you should consult your doctor.
