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Beta-Ecdysterone (20-Hydroxyecdysone, Ecdysterone or 20E) is a natural hormone-like substance that controls the process of molting and metamorphosis in arthropods. Ecdysterone is the most commonly found hormone in insects, crabs, and other representatives of the class.
Separately, phytoecdysterone is isolated, which is present in plants: Cyanotis vaga, Leuzea safflower, Yuppie, Suma, Turkistan tenacious and others; its function, according to scientists, is to suppress the reproduction of insect pests.
Ecdysterone has biological effects in humans, but there is still much controversy on this issue. Most modern supplements are made from the plant Cyanotis vega and Leuzea safflower.
Contraindications
- hypersensitivity to the components of the drug;
- insomnia;
- nervous excitement;
- epilepsy;
- arterial hypertension;
- stage of exacerbation of peptic ulcer of the stomach and duodenum;
- hyperkinesis;
- congenital fructose intolerance;
- sucrase/isomaltase deficiency;
- glucose-galactose malabsorption;
- age under 18 years;
- pregnancy;
- lactation period.
Ecdisten is used with caution to treat patients with diabetes mellitus, as well as people on a diet with a low concentration of carbohydrates.
Indications for use of Ecdisten
The drug Ecdisten is used as a tonic for asthenodepressive and asthenic conditions, expressed in weakness and depression of the patient. Which can be caused by: weakening of protein synthesizing processes, neuroses, neurasthenia, prolonged intoxication, low blood pressure.
The drug is recommended by athletes during intense training in the presence of dysfunction of the cardiovascular system, especially with obvious signs of myocardial overstrain and increased protein catabolism. Reviews left by sports doctors about the use of Ecdisten showed its effectiveness in increasing speed and strength qualities in the period before competitions.
special instructions
During treatment with Ecdisten, to achieve an effect, it is necessary to ensure the simultaneous intake of adequate amounts of carbohydrates, fats, proteins, minerals and vitamins with food.
In case of side effects, including to avoid disruption of normal sleep, it is recommended to reduce the dose or stop taking the drug in the evening.
Patients with diabetes should take into account that 1 tablet of the drug contains carbohydrates in an amount of about 94 mg (0.008 XE).
The use of the drug does not affect the ability to engage in hazardous activities that require rapid psychomotor reactions and high concentration (for example, driving vehicles).
Mode of application
Taken 3 times a day, orally, before meals. Single dosage 0.005-0.01 g. The general course of therapy is 15-20 days. If necessary, the course can be repeated after a 1-2 week break.
The maximum single dose is 0.025 g, the maximum daily dose is 0.1 g. In sports medicine, it is recommended to take the drug for 2-3 weeks, 3 times a day, 0.01-0.02 g.
When taking Ecdisten, it is recommended to maintain an adequate diet, including proteins, carbohydrates, fats, vitamins, and minerals, to obtain the maximum effect.
Manufacturers' descriptions
Scientists who studied Ecdisten came to incredible conclusions: under the influence of Ecdisten, muscle anabolism increases by 190-200%, which is comparable to Methandrostenolone injections. How does Ecdisten act on human muscles?
Scientists claim that Ecdisten stimulates protein synthesis in the cytoplasm of muscle cells by accelerating the synthesis of protein chains from amino acids. It is assumed that Ecdisten increases the concentration of potassium and calcium ions inside the muscle cell, and this in turn causes an increase in the synthesis of DNA, RNA and protein.
As for side effects, Ecdisten is not only safe, but also useful! It prevents cortisol from destroying cells and normalizes creatine synthesis. Increases the adaptive abilities of the heart, improves liver function and blood composition! Amazingly, being a powerful anabolic steroid, Ecdisten does not suppress the body’s secretion of testosterone.
The same thing happens with growth hormones. Those who have been on steroids for a long time are usually forced to give themselves injections of growth hormone, while even many years of taking Ecdisten not only does not weaken the natural production of somatotropin, but even increases it!
Ecdisten, unlike steroids, sports doctors recommend taking 30-50 mg daily, but the dose can be increased to 100 mg without the risk of complications - it all depends on your financial capabilities.
Ecdisten has been used in sports since 1985, and in the former Eastern Bloc countries, the study of Ecdisten's effects was put on a solid scientific basis. Ecdisten was often given to elite strength athletes, achieving a powerful “steroid” effect. Then they learned about Ecdisten in Europe. His styles are widely used in the US weightlifting team.
The head coach of the American security forces, Dragomir Charoslan, says: “Our training program is so difficult and serious that there can fundamentally be no place for useless substances in it. As for Ecdisten, it really increases strength, muscle size and speeds up recovery.” Today Ecdisten is one of the most popular sports supplements in the diet of elite athletes in all countries.
“Ecdisten is simply irreplaceable for strength training,” says the American and world-famous athletic trainer and consultant Jay Schroeder, “it allows athletes to achieve a level of training that we could only dream of before.”
Sources[edit | edit code]
- Slama K, Koudela K, Tenora J, Mathova A: Insect hormones in vertebrates: anabolic effects of 20-hydroxyecdysone in Japanese quail. Experientia 1996, 52(7):702-6.
- Slama K, Kodkoua M: Insect hormones and bioanalogues: their effect on respiratory metabolism in Dermestes vulpinus L. (Coleoptera). Biol Bull 1975, 148(2):320-32.
- Tashmukhamedova MA, Almatov KT, Syrov VN, Sultanov MB, Abidov AA: . Nauchnye Doki Vyss Shkoly Biol Nauki 1985(9):37-9.
- Syrov VN: . Nauchnye Doki Vyss Shkoly Biol Nauki 1984(11):16-20.
- Kholodova Y: Phytoecdysteroids: biological effects, application in agriculture and complementary medicine (as presented at the 14th Ecdysone Workshop, July, 2000, Rapperswil, Switzerland). Ukr Biokhim Zh 2001, 73(3):21-9.
- Toth N, Szabo A, Kacsala P, Heger J, Zador E: 20-Hydroxyecdysone increases fiber size in a muscle-specific fashion in rat. Phytomedicine 2008, 15(9):691-8.
- Wilborn C, Taylor L, Campbell B, Kerksick C, Rasmussen C, Greenwood M, Kreider R: Effects of methoxyisoflavone, ecdysterone, and sulfo-polysaccharide supplementation on training adaptations in resistance-trained males. Journal of the International Society of Sports Nutrition 2006., 3(2).
Objective description
Currently, there is no reliable information about the action and effectiveness of ecdisides, with the exception of information provided by Russian scientists. Unfortunately, all research data are not statistically reliable, since the experiments do not meet modern requirements: the presence of a control group, randomization, multicenter, and so on, most of them were carried out on animals.
Thus, it cannot be said for sure whether Ecdisten is a potent anabolic agent in humans until large-scale controlled studies are conducted.
Pharmacies in Moscow where you can buy Ecdisten, compare prices and make a pre-order
Natural compound of steroid structure from the roots and rhizomes of Leuzea safflower; has a tonic effect, helps to enhance the processes of protein synthesis in the body. Increases mental and physical performance.
Compound:
Active ingredient: ecdisthene.
Excipients: sugar (sucrose), potato starch, calcium stearate.
Indications:
- Asthenic syndrome associated with weakening of protein synthesizing processes;
- with prolonged intoxication, infections;
- mental and physical fatigue;
- in athletes, as a medicine that increases speed and strength qualities during preparation for competitions.
Application:
Orally 0.005-0.01 g (1-2 tablets) 3 times a day after meals. The course of treatment is 15-20 days. On the recommendation of a doctor, it is possible to carry out a second course of treatment after 1-2 weeks.
In sports medicine, use 0.01 g (2 tablets) 3 times a day for 2-3 weeks. The maximum single dose is 0.01 g (2 tablets), the maximum permissible daily dose is 0.03 g (6 tablets).
Side effect:
Insomnia, increased blood pressure, and pain in the epigastric region are possible.
If any of the side effects indicated in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor immediately.
Contraindications for use:
- nervous excitement;
- insomnia;
- arterial hypertension;
- epilepsy;
- hyperkinesis;
- peptic ulcer of the stomach and duodenum (in the acute stage);
- congenital fructose intolerance;
- glucose-galactose malabsorption;
- sucrase/isomaltase deficiency;
- pregnancy;
- lactation period;
- age under 18 years;
- increased individual sensitivity to the components of the drug.
If you have at least one of the listed diseases, be sure to consult your doctor before taking the drug.
Use with caution in patients with diabetes and those on a low-carbohydrate diet.
Use during pregnancy and breastfeeding:
The drug is contraindicated during pregnancy and lactation.
Use in children:
Contraindicated in children under 18 years of age.
Special instructions:
To achieve the effect, simultaneously with the use of the drug, it is necessary to receive adequate amounts of proteins, fats, carbohydrates, vitamins and minerals from food.
In case of side effects, incl. To avoid sleep disturbances, it is advisable to reduce the dose or stop taking the drug in the evening.
Patients with diabetes should take into account that one tablet of the drug contains about 0.094 g of carbohydrates (0.008 XE).
Impact on the ability to drive vehicles and operate machinery:
The use of the drug does not affect the ability to drive vehicles or engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
Overdose:
Symptoms:
Dose-dependent adverse reactions may increase.
Treatment:
Symptomatic.
Interaction with other drugs and preparations:
With simultaneous use, it is possible to enhance the effect of stimulants and analeptics (caffeine, camphor, phenamine).
The drug is an antagonist of drugs that depress the central nervous system (including antipsychotics, barbiturates, tranquilizers, anticonvulsants).
The online pharmacy help from the Pharmindex website will help you find and buy Ecdisten in pharmacies at the best price.
Claimed effects of Ecdisten
Study on 3 groups of people: 1) training only 2) training + protein 3) training + protein + Ecdisten
- increased protein synthesis
- increased supply of protein and glycogen to muscles
- stabilizes blood sugar levels, improving hypoglycemia in cutting athletes
- prevents fat deposition by stabilizing blood sugar and insulin levels
- reduces cholesterol levels in the blood
- stabilizes cell membranes
- has a beneficial effect on heart rate
- antioxidant effect
- anti-catabolic effect
- cleanses the skin
- increases strength and endurance
- increases “lean” muscle mass
- reduces fat mass
Ecdisten doses
You should pay special attention to the doses of Ecdisten!
In all studies where positive results were obtained, Ecdisten was used in doses equivalent to 500 mg per day for humans. However, most manufacturers and supplements of Ecdisten contain several tens of times smaller doses (Ecdysten B - 25 mg, Ecdysten ACE - 70 mg, Ecdysten MEGA - 25, Ecdysten from ThermoLife - 15 mg and others).
If you see that the dose is below 100 mg, then this supplement is completely useless. However, recently new supplements with adequate doses have appeared: EcdySterone from SciFit - 300 mg, SyntraEC from Syntrax - 275 mg and others.
