Currently, due to poor lifestyle, a large number of people are suffering from numerous liver diseases. Instructions for use Phosphogliv forte lists this medication as an effective hepatoprotector of combined action that can solve many problems.
Based on the information received, you will learn how to use it correctly, how it interacts with other drugs and substances, as well as analogues that allow you to achieve a similar effect.
Compound
Each capsule contains the following active ingredients:
- 400 mg lipoid ;
- 300 mg of phospholipids (the main one is phosphatidylcholine, which makes up 73-79% of the total);
- 65 mg sodium glycyrrhizinate.
The following substances are contained in each capsule as auxiliary ingredients:
- “extra” or “luxury” grade ethanol;
- butylated hydroxytoluene;
- sunflower or corn oil.
The capsule shell consists of:
- titanium dioxide;
- dyes: red, black and yellow iron oxides;
- gelatin.
Reviews
If you have discovered liver diseases, then Phosphogliv forte will be the most clear and effective way to get rid of them. Despite the rather high price, the result obtained will be worth the cost, since the drug has proven its value in clinical trials.
Before buying a medicine, you should definitely study all its positive and negative properties, since pharmacy counters sell many products with varying degrees of effectiveness, so it is possible to buy a low-quality drug, for which you will simply throw a large sum down the drain.
Marina Maksimova
Gastroenterologist, Candidate of Medical Sciences and editor of articles at gastro911.com. For more than 10 years I have been helping to recover from gastrointestinal diseases.
Release form
The medicine is available in the form of hard gelatin capsules. The body and cap of the capsule are brown. The contents are an oily paste-like mass. The color of this mass ranges between light yellow and orange-brown. Characterized by a weak specific odor.
Capsules are packaged in blister packs of 10 pieces or in plastic containers of 30, 50, 100, 200 or 300 pieces. Cellular packaging is placed in cardboard packs of 2, 3 or 5 pieces. Each container is placed in a separate cardboard box.
Drug interactions
Clinical trials have shown that Phosphogliv forte does not interact with drugs from other groups, so it can be used in combination with other drugs for complex therapy.
Interaction between Phosphogliv forte and alcohol
Alcohol itself is a substance harmful to the liver, so the simultaneous use of a drug designed to improve liver function and alcohol-containing substances, on the contrary, worsening it, is not recommended.
However, in extreme cases, it is allowed to drink a small dose of alcohol, since at the chemical level these two substances do not interact with each other.
Drinking alcohol is allowed during the period between courses of treatment with Phosphogliv forte, but in small quantities.
Impact on ability to drive
Phosphogliv forte does not affect the nervous system at all and does not cause drowsiness, so there are no restrictions on driving.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Phospholipids, in particular phosphatidylcholine, are structural elements of cell walls and intracellular membranes. Entering the body when taking medication, they promote the restoration of damaged liver cells, inhibit the formation of connective tissue and the replacement of normal tissue with connective tissue elements (prevention of fibrosis ).
Glycyrrhizic acid suppresses inflammatory processes and the ability of viruses to reproduce. This is due to the fact that it stimulates the production of interferons and phagocytosis. Glycyrrhizic acid also has an antioxidant and membrane-stabilizing effect.
Pharmacokinetics
All components of the drug and their active metabolites are very well absorbed in the intestines. through the bloodstream to the organs of the human body, which they actively influence.
pharmachologic effect
Phosphogliv Forte belongs to the category of combination drugs. The medicine is characterized by the presence of a membrane-stabilizing effect. It also has antiviral and hepatoprotective properties.
The main component of phospholipids is phosphatidylcholine. It is the main structural element of the intracellular and cellular membrane. With its help, the restoration of structure and function in case of damage is ensured. This component has cytoprotective properties.
During the period of use of Phosphogliv Forte, normalization of lipid and protein metabolism is ensured. Thanks to the action of the drug, the loss of enzymes by hepatocytes is prevented. The drug is recommended for use to restore the detoxification function of the liver. The active ingredients of Phosphogliv Forte inhibit the formation of connective tissue. That is why the medicine is widely used for the prevention of fibrosis and cirrhosis of the liver.
The drug consists of glycyrrhizic acid - glycyrrhizic acid and salt. This component is characterized by the presence of anti-inflammatory properties. With its help, the reproduction of viruses in organs is suppressed. This is ensured by the process of stimulating the production of interferons. During the period of use of Phosphogliv Forte, phagocytosis increases significantly. The use of the drug will increase the activity of natural killer cells. This component has antioxidant and membrane-stabilizing activity, which provides it with hepatoprotective properties. The action of the component is aimed at potentiating glucocorticosteroids of endogenous origin. It has antiallergic and anti-inflammatory properties. That is why Phosphogliv Forte is recommended for use for non-infectious liver lesions.
If a patient is diagnosed with skin lesions, then he is recommended to use this drug. Thanks to its anti-inflammatory properties, it stops the progression of the disease.
After taking Phosphogliv Forte, rapid absorption of its components in the intestine is observed in two forms - the whole molecule or the bioactive form of their hydrolysis, which act as glycerretic acid, unsaturated fatty acids, and choline. After absorption through the intestinal walls, their absorption into the affected organs is observed, which ensures the highest possible effect of the medication.
Phosphogliv Forte is a universal medicine whose action is aimed at restoring liver function.
Indications for use
The use of Phosphogliv Forte is indicated for:
- acute and chronic forms of viral hepatitis ;
- hepatosis (fatty liver degeneration);
- liver damage caused by medications, alcohol, and other toxins;
- liver cirrhosis;
- intoxications of various origins;
- some skin diseases ( psoriasis , neurodermatitis , eczema ).
Undesirable effects
If the medicine Phosphogliv Forte is used incorrectly, the development of undesirable effects may occur. If a person has hypersensitivity to the components of the drug, complications manifest as a skin rash. The undesirable effect goes away on its own after you stop taking the drug.
The use of the medication must be carried out in strict accordance with the dosage specified by the doctor. Otherwise, undesirable effects may occur. Most often they manifest themselves in the form of sodium and fluid retention in the body. Against this background, the patient experiences peripheral edema. With pathology, the patient's blood pressure increases. The disease is accompanied by hypoglycemia.
If the above symptoms occur, patients are advised to reduce the dosage of the medication they are taking. If after this the signs of undesirable effects remain pronounced, then the drug should be abandoned and replaced with analogues.
Phosphogliv Forte may cause undesirable effects. That is why its use should be carried out after preliminary consultation with a doctor. Antral is characterized by high efficiency. With its help, chronic and acute hepatitis and gallbladder diseases are cured. The use of Apkosul is recommended for complex treatment of pathological processes in the liver. Vimliv is prescribed to patients with toxic liver damage, chronic viral hepatitis, and bladder dyskinesia. With the use of Bonjigar, the use of chronic hepatitis is recommended, regardless of their etiology.
Analogues of Phosphogliv Forte
Level 4 ATC code matches:
Hepatosan
Sirepar
Hepatomax
Phosphogliv
Thiotriazolin
Karsil Forte
Darsil
Silibor
Karsil
Erbisol
Silimar
Methionine
Remaxol
Enerliv
Laennec
Progepar
Antral
Potassium orotate
Legalon
Hepa-Merz
Drug analogues:
- Antral;
- Apkosul;
- Bonjigar;
- Vimliv;
- Hepa-Merz;
- Gepabene;
- Hepalex;
- Heparete;
- Heparsil;
- Hepatofalk;
- Hepafil;
- Hepaforte;
- Hypoglisil;
- Glutargin;
- Glutarsol;
- Darsil;
- Karsil;
- Levasil;
- Legalon;
- Lecithin;
- Livenziale;
- Livolact;
- Ornitox;
- Remaxol;
- Silibor;
- Triliv.
Use in patients with hepatitis C
To maintain normal liver function in hepatitis C, the patient is prescribed treatment with Phosphogliv Forte. Such therapy makes it possible to prevent or slow down the development of fibrotic changes in the organ. To achieve positive results from use, you need to take 1-2 capsules of this medicine 3 times a day with meals. The duration of such therapy should average 1 year or more. Do not forget that the active components reduce the activity of AST and ALT, so you should additionally take liver enzymes. This will ensure normal functioning of the organ.
Price Phosphogliv Forte, where to buy
The price of Phosphogliv Forte in Russian pharmacies is 800-950 rubles for 50 capsules. The cost in Ukrainian pharmacies is 700-900 hryvnia for a similar package.
- Online pharmacies in RussiaRussia
- Online pharmacies in KazakhstanKazakhstan
Pharmacy Dialogue
- Phosphogliv forte (caps. No. 50) FS.-Leksredstva
1031 rub. order
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Contraindications
Phosphogliv forte is a relatively safe drug, so the list of contraindications is very small. You can't use it:
- if you have individual intolerance or hypersensitivity to any of the components of the drug;
- during pregnancy or lactation until the child is completely weaned;
- until the child reaches 12 years of age.
In all other cases, Phosphogliv forte is an excellent medicine.
Analogs and which one is better
Analogs of “Phosphogliv Forte” include the following:
- Essentiale forte N;
- Essentialgliv;
- Essliver forte;
- Rezalut Pro.
It can also be replaced by hepatoprotectors from another pharmacological group: amino acids (Heptral, Samelix, Heptor), herbal preparations (Liv.52, Silimar).
Essentiale forte
Patients often ask their hepatologists which is better - Phosphogliv Forte or Essentiale Forte.
The latter contains only essential phospholipids and is produced in Germany. And the Russian hepatoprotector has a combined composition. Their areas of application and possible side effects are similar. "Phosphogliv forte" has a complex effect on the affected liver. He can not only eliminate the consequences of degenerative processes, but also influence the mechanisms that triggered them. Its effect on the liver is more pronounced.
Essliver forte
Some patients want to figure out which is better - Phosphogliv Forte or Essliver Forte. You need to start with the composition. The latter drug contains essential phospholipids and B vitamins. Taking this into account, for hepatitis it is more appropriate to take Phosphogliv, since it also has antiviral and anti-inflammatory activity, which Essliver Forte does not have.
In another situation - with dystrophic liver damage and intoxication - a combination of phospholipids and vitamins is better. The recovery will be more dynamic. Both drugs have proven themselves to be the best. But it is up to the attending physician to decide which one is more suitable for a particular patient.
Essential phospholipids, together with vitamins, have a powerful restorative effect on hepatocytes.
Review of reviews about liver restoration with this drug
Reviews about Phosphogliv Forte are mostly positive. Many people call it a natural helper for the body. In reviews, patients note that the instructions for use of Phosphogliv Forte are simple. There are no special instructions during therapy.
Those who have completed a full therapeutic course of liver restoration with this drug note that there is no trace of pain in the right hypochondrium, even if you slightly deviate from the diet. In reviews, patients usually do not say which is better - Phosphogliv or Phosphogliv Forte, since both drugs are effective and it all depends on the stage of liver damage.
This hepatoprotector is praised by those who had to restore their liver after various types of intoxication. And some, with its help as part of complex therapy, managed to defeat psoriasis.
In most cases, the drug in question is well tolerated, but cases of hypertensive crises or allergic reactions cannot be excluded.
Instructions for use
The use of Phosphogliv Forte should be prescribed exclusively by the attending physician. He will conduct a full diagnosis, which will allow him to prescribe more accurate treatment.
We strongly recommend that you read the instructions for use before starting treatment - this will help avoid side effects. In general, Phosphogliv Forte should be used as follows:
- Children over 12 years old – 1 capsule 3 times a day;
- Adults – 1-2 capsules 3 times a day.
Capsules should be swallowed completely with plenty of water. It is best to do this while eating. This will improve the absorption of beneficial elements. Any changes to the treatment regimen should be made by a qualified specialist.
