Pharmacodynamics and pharmacokinetics
Pharmacodynamics
The pharmacological effect of the drug is due to the biologically active compounds of herbal medicines included in the sedative collection No. 3.
Valerian officinalis - contains a number of essential oils that have a pronounced sedative effect: menthol, ester of isovaleric acid and borneol , tannins, valeric and other organic acids, alkaloids ( chatinin , valerine ), sugars. As a result of their influence, the duration of sleep in patients is normalized, and the process of falling asleep improves. Effective for emotional tension and increased excitability.
Oregano - contains flavonoids , thymol , tannins . In infusion form it has a sedative effect.
Motherwort herb is a combination of essential oils, alkaloids , iridoids , tannins, saponins , carotenes that have a strong sedative effect. The herb is especially effective for increased nervous excitability, neurocirculatory dystonia, various sleep disorders, neurasthenia, and in the initial stages of hypertension .
Sweet clover herb contains coumarins , tannins, melilotoside , dicumarol , polysaccharides , saponins , flavonoids , which are effective for migraine , sleep phase dissonance, neurasthenia .
Creeping thyme herb - active compounds are thymol , borneol , terpinene , terpineol and other terpene compounds, tannins, ursolic , oleanolic , chlorogenic acids , bitterness, flavonoids and mineral salts. It has an antispasmodic effect and a weak hypnotic effect.
Release form and composition
Dosage form - crushed collection: a mixture of plant materials in the form of heterogeneous green-whitish particles interspersed with yellow and pinkish-violet color, with a strong aromatic odor; the aqueous extract has a bitter, spicy taste (25, 50 or 100 g each in paper, heat-sealable, polypropylene bags, in moisture-resistant paper bags or in parchment bags, 1 bag in a cardboard pack; 2 g in filter bags, in a cardboard box a pack of 10 or 20 filter bags).
100 g of crushed collection contains:
- rhizomes with roots of valerian officinalis – 17 g;
- motherwort herb – 25 g;
- oregano herb – 25 g;
- creeping thyme herb – 25 g;
- sweet clover grass – 8 g.
Calming collection No. 3, instructions for use (Method and dosage)
Two tablespoons of the collection or 1 filter bag are poured into 200 ml of hot water, boiled in a water bath for 15 minutes, left for 45 minutes, the raw materials are squeezed out and filtered. The resulting volume of infusion is adjusted to 200 ml with water. Take 1/3 cup half an hour before meals, 2 times a day. If you have problems falling asleep, take the infusion an hour before bedtime.
The course duration is 2-4 weeks. After which you should take a break and, if necessary, repeat the course. Do not take one collection for more than 6 months intermittently, the body may get used to the effects. If you are prone to allergic reactions, you do not need to start taking the collection with the recommended dose, and gradually increase the intake to the required dose, monitoring your condition.
special instructions
The recommended dosage should not be exceeded.
A sustained therapeutic effect occurs after 10–14 days of regular use of the infusion.
If necessary, the finished infusion can be stored in the refrigerator for 2 days.
Impact on the ability to drive vehicles and complex mechanisms
Long-term use of the infusion in high doses can cause a decrease in the speed of psychomotor reactions. Therefore, you should be careful when driving vehicles and working with complex mechanisms.
Reviews of sedative collection No. 3
Preparing the collection yourself is a labor-intensive process and difficult to implement. You can always buy ready-made herbal mixtures at the pharmacy, in this case it is Phytosedan No. 3. A collection of five plants that have the same direction has a sedative and moderate hypnotic effect. Has a beneficial effect on the nervous system and emotional sphere. In some situations it is simply irreplaceable, as evidenced by reviews of those who took this collection.
- “...Wonderful natural tea. I have been using it for many years during periods of intense work, nervous stress and anxiety. It always helped, but you really need to drink regularly, at least for a week”;
- “... I buy it in filter bags, it’s very convenient to brew at work. During periods of nervous tension and poor sleep, I give up tea and coffee, replacing them with infusion”;
- “... This decoction helps me - it relieves tension and does not cause drowsiness. I take it as recommended in the instructions 2 times a day, sometimes only at night, but there is still an effect!!”;
- “... I didn’t even expect such an effect. Work involves constant communication with people, and they are different. I drink herbal teas at work, they relieve nervous tension and calm me down”;
- “... A pleasant herbal infusion that gives an excellent calming effect and ensures sound sleep”;
- “... Krasnogorsk herbs are perhaps the best in terms of preparation technology. Calming preparations are a miracle!”;
- “... With the help of Phytosedan No. 3 I normalize my condition after stress, I also take it for insomnia. Usually a course of 2 weeks is enough for me to get everything right.”
When taking decoctions and infusions of herbs, you need to take into account that you need to drink them in doses, and to get the effect, take a course of at least two weeks.
pharmachologic effect
Breast collection 3, the composition of which is distinguished by its healing properties, is capable of providing a powerful anti-inflammatory, expectorant and antipyretic effect.
To get acquainted with the full pharmacodynamic picture of the drug, it is better to study the properties of each of its components separately:
| Component | Description |
| Anise berednets | A plant with antispasmodic and bactericidal effects. Improves the dilution and separation of mucus from the mucous membrane of the respiratory tract. Destroys pathogens that cause viral cough. |
| Licorice root | Glycyrrhizin, contained in licorice roots, stimulates the activity of cilia in the epithelial cells of the bronchi and trachea. Glycyrrhizic acid suppresses inflammatory reactions and promotes the growth of secretory activity in the mucous membrane of the respiratory tract. |
| Scots pine | Resin, starch and tannins dilute viscous mucus in the bronchi and have a bactericidal effect on pathogenic microflora of the oral cavity and the lateral walls of the oropharynx. Thanks to essential oils, the process of expectoration of sputum is facilitated. |
| Salvia officinalis | The crushed leaves of this plant accelerate the healing of affected areas of the mucous membrane. They have antimicrobial and astringent properties. Phenolcarboxylic acids effectively fight inflammation. |
| Marshmallow (marshmallow) | Its roots are included in the group of antitussives. Heterogeneous mucus moistens the vocal folds, fights plaque on the walls of the trachea, providing an enveloping effect. |
Thanks to herbal components, herbal infusion No. 3 has a bronchodilator effect. If you regularly use this drug during a cold, the bronchi will expand and the respiratory muscles will relax.
Price of sedative collection No. 3, where to buy
You can purchase this collection at any pharmacy in Moscow or pharmacies in other cities. The cost of 20 filter bags ranges from 60 to 89 rubles per package.
- Online pharmacies in RussiaRussia
ZdravCity
- Phytosedan (Soothing collection No. 3) PharmaColor 2g filter pack.
20 pcs. JSC Krasnogorskleksredstva 89 rub. order
Indications
Cough can be either wet or dry, and the mechanism of development of symptoms is different for them. A dry cough is triggered by chemical or mechanical irritation of the receptors that are located in the mucous membrane of the pharynx and larynx. And the catalyst for a wet cough is a dysfunction of the bronchial glands. Chest collection 3 is prescribed for severe irritation of the respiratory tract, which interferes with air flow, with mucus difficult to clear.
The composition of the drug, which dilates blood vessels and reduces the intensity of inflammation in the upper respiratory tract, will be effective for the following diagnoses:
- infectious tracheitis, tracheobronchitis;
- pharyngitis, laryngitis, and other diseases caused by staphylococci/streptococci;
- tuberculosis;
- acute respiratory viral infections;
- inflammation of the lung tissue (pneumonia);
- bronchial asthma;
- any type of bronchitis (fungal, bacterial, asthmatic).
It is important to select a herbal preparation based on the symptomatic picture. It is even better to consult a doctor so that he can draw up a treatment regimen.
Contraindications and side effects
It is strictly forbidden to combine treatment with a herbal mixture with cough suppressants. It should also not be taken by patients who have individual intolerance to any of the components, cardiovascular insufficiency, or kidney disease. It is advisable to refrain from breastfeeding therapy for women during pregnancy and lactation, and people with seasonal allergic rhinoconjunctivitis.
Experts prohibit giving the drug to children under 3 years of age. There are no serious side effects from treatment with this herbal medicine. An allergic reaction to certain ingredients of the drug may become more active. As a rule, the symptoms of an allergy are a runny nose, severe itching, and increased body temperature. In rare cases, patients complain of disruption of the gastrointestinal tract.
Overdose
Due to long-term therapy (more than 3-6 weeks) or exceeding the dose of herbal medicine, hypokalemia develops, blood pressure increases, and heart rhythm is disturbed.
Symptoms such as:
- excessive accumulation of gases in the intestines, frequent loose stools;
- angioedema (less commonly, anaphylactic shock);
- myopathy, myoglobinuria;
- hypertensive encephalopathy;
- headache of varying severity, which entails weakness, apathy and drowsiness.
If one of these symptoms of overdose makes itself felt, you should immediately stop taking the medication and, if possible, visit a doctor. He will determine the scheme for further use of the herbal medicine or replace it with something else. It is worth noting that there is currently no medicine with a specific effect that could stop or weaken the effect of an overdose.
Interaction
It is strictly not recommended to take chest collection 3 simultaneously with antitussive drugs that minimize the rate of sputum formation. And also with medications that contain codeine/dextromethorphan. Licorice root, which is one of the components of the herbal medicine, prevents the action of medications that lower blood pressure.
When combining a herbal-based medicinal complex with cardiac glycosides, diuretics/laxatives, and antiarrhythmic drugs, the level of potassium in the blood plasma may decrease. Therefore, you should not take such medications together either. Simultaneous use of antitussive collection No. 3 with antiarrhythmic drugs is fraught with a severe form of ventricular tachycardia.
The heartbeat will become faster due to the increase in the number of ventricular contractions. If you ignore the incompatibility of the herbal medicine with such substances, this will result in insufficient blood supply and provoke loss of consciousness.
All medications that are taken regularly must be reported to your doctor. Otherwise, the main pharmaceutical substances will either be weakened or strengthened. The manufacturer offers a complete list of medications that should not be combined with herbal tea on the packaging or in the instructions inside the box. Drinks containing alcohol should never be consumed during therapy.
