Pharmacological action of Laktogin
Laktogin increases the number of lactobacilli in the vagina and stabilizes its microflora.
The live bacteria contained in the preparation, isolated from the urogenital tract of healthy women, populate the vagina with disturbed microflora and begin to produce hydrogen peroxide, lactic acid and other biologically active substances, thereby helping to restore the natural acidic environment in the vagina and making the vaginal mucosa more resistant to exposure harmful microorganisms.
Laktogin relieves burning, itching, discomfort in the perineum - symptoms of vaginitis.
The use of Laktogin reduces the likelihood of recurrence of the disease.
Side effects
Usually, the use of both forms of Laktogin is well tolerated, but in rare cases the following are possible:
Allergic reactions:
In the genital area:
- discomfort;
- burning;
- itching
As a rule, these side effects are inherent after the use of suppositories, and in the case of these phenomena, it is advisable to switch to oral administration of the drug.
Indications for use of Laktogin
According to the instructions, Laktogin is used as a biologically active food supplement for:
- vaginal dysbiosis as monotherapy and as part of combination therapy;
- during and after antibiotic therapy, treatment with corticosteroids, cytostatics, antiviral and antifungal drugs;
- during and after antiviral, antimicrobial, immunomodulatory therapy for sexually transmitted infections (human papillomavirus infection, chlamydia, gonorrhea, urogenital herpes and others);
- chronic and subacute inflammatory processes of the genital area;
- preparation for therapeutic and diagnostic gynecological procedures;
- preparing pregnant women for childbirth;
- hormonal-dependent colpitis as monotherapy or together with the use of specific hormonal drugs;
- the use of contraceptives such as spermicides, COCs, IUDs.
Laktogin
Laktogin is a biologically active substance that belongs to the group of probiotics. It is designed to restore healthy microflora in the vagina. Today this drug can be purchased under the name Vagilac, since its trade name was changed in 2008.
Composition and release form
The biologically active substance Laktogin is available in two forms: suppositories and capsules. Each capsule contains 109 lactobacilli Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14. Each package contains 15 capsules. Laktogin suppositories contain strains of live lactobacilli such as Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14. In addition, they contain excipients such as cellulose, starch, dextrose and others.
pharmachologic effect
According to the instructions, Laktogin contains a combination of lactobacilli, which are normally found in the urogenital tract of a woman. The donors for the production of this drug are absolutely healthy women, from whose bodies the necessary strains of bacteria are isolated. After using Laktogin suppositories, bacteria colonize the entire vagina and begin to work, secreting lactic acid, as well as water peroxide and other substances necessary to maintain the genitals in normal condition and protect against pathogenic bacteria.
The use of oral capsules helps achieve the same effect. The vagina is populated with beneficial microflora, which creates an acidic environment in it, approximately pH 3.8 - 4.5. This environment is optimal for the functioning of normal vaginal microflora, but is destructive for most pathogenic microorganisms.
Lactogine is effective in the treatment of bacterial vaginitis. After using the drug, itching, burning and other unpleasant sensations in the perineal area disappear, and any discomfort associated with the activity of pathogenic or conditionally pathogenic bacteria is eliminated. When treating diseases caused by the activity of pathogenic microorganisms, the use of Laktogin tablets or suppositories reduces the likelihood of disease relapse by 80%.
Indications
According to the instructions, Laktogin should not be used by women under 18 years of age.
Typically, the use of this dietary supplement is recommended in the treatment of vaginal dysbiosis, both as an independent drug and as part of complex therapy. It is also often used as an adjuvant in the treatment of infectious and inflammatory diseases of the genital area in women, both acute and chronic. The use of this drug during treatment with antibiotics, cytostatics, antifungal and antiviral drugs and corticosteroids is very effective. It is used both during and after treatment to normalize the vaginal microflora. According to the instructions, Laktogin is indicated during prenatal preparation in women. It is also often recommended in preparation for a variety of diagnostic procedures and gynecological operations. Including the use of this drug is recommended before installing an intrauterine device.
Instructions for use (method and dosage)
If it is necessary to normalize the vaginal microflora, it is recommended to take one capsule of Laktogin daily. If there is an inflammatory disease of the vagina, the dosage should be increased to two capsules per day. Take capsules on an empty stomach or no earlier than two hours after meals.
Laktogin suppositories are usually used one per day. They must be inserted at night, after cleansing and douching the vagina.
Contraindications
Laktogin is well tolerated and causes minimal side effects, but according to the instructions, taking this drug is contraindicated in case of documented hypersensitivity to any of its components.
Side effects
The drug can cause allergic skin reactions in the genital area, which are accompanied by itching, burning sensation and discomfort. This side effect is more typical for Laktogin suppositories and usually goes away if you stop using them. In this situation, it is better to switch to oral administration of this drug in capsule form.
Directions for use and dosage of Laktogin
Laktogin capsules are intended for oral administration.
Capsules are taken during meals with liquid, 1 capsule per day for 2-6 weeks. If necessary, the course of treatment is repeated.
When using Laktogin capsules as part of a complex treatment of chronic inflammatory diseases of the female genital organs, during and after antibiotic therapy, take 1 capsule 2 times a day.
When treated with oral antibiotics, take this medication two hours before or two hours after taking antibiotics.
Laktogin suppositories are administered before bedtime.
Before inserting Laktogin suppositories, vaginal douching is performed.
Normalization of vaginal microflora occurs two weeks after the start of therapy and no later than 4-6 weeks after that.
Release form, composition and packaging
The drug Laktogin is produced:
- In the form of capsules.
Active ingredients: 1 capsule contains 109 lactobacilli Lactobacillus reuteri RC-14 and Lactobacillus rhamnosus GR-1.
There are 15 capsules in a cardboard package.
- In the form of candles.
Active ingredients: 1 suppository contains live strains of lactobacilli Lactobacillus reuteri RC-14 and Lactobacillus rhamnosus GR-1 directly.
Auxiliary components: dextrose, cellulose, starch.
Laktozhinal or Vagilak
Vagilak is an analogue of Laktozhinal suppositories in the form of capsules taken orally. The drug contains two strains of lactobacilli. Helps normalize and improve vaginal microflora, prevents the development of bacterial and fungal infections.
Compared to Laktozhinal suppositories, Vagilak capsules are approved for the treatment of gynecological diseases in girls from 10 years of age.
Important! When purchasing a medicine, pay attention to the storage conditions of Vagilak. In the pharmacy it should be in the refrigerator; when used, it is permissible to place the package with the medicine at room temperature.
The medicine is taken orally twice a day for treatment and once a day for prophylactic purposes. The course of treatment is determined by the state of the microflora and the severity of the disease and lasts 2–4 weeks.
The disadvantage of Vagilak is the high price of the course - 2-4 packages are needed for treatment. Please note that the analogue refers to dietary supplements.
What to choose - Laktozhinal or Vagilak suppositories depends on the condition, indications, contraindications, and financial capabilities. Please consult your doctor before purchasing.
Conditions for storage and release from pharmacies
Laktogin should be stored in a cool, dry and dark place out of the reach of children. The shelf life is one and a half years. Laktogin capsules and suppositories are available from pharmacies without a doctor's prescription.
Information about the drug is generalized, provided for informational purposes and does not replace official instructions. Self-medication is dangerous to health!
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Laktozhinal or Gynoflor E
An analogue of Laktozhinal suppositories are vaginal tablets Gynoflor E, created by a foreign manufacturer. One of the differences is the combined composition. In addition to the eubiotic, which normalizes and improves the vaginal microflora, the drug contains the hormone estriol . The latter, using a special mechanism, promotes the production of glycogen to create optimal conditions for the proliferation of lactobacilli and lactic acid, which maintains pH levels.
Tablets are used intravaginally, 1–2 tablets per day for 6–12 days. The course of treatment depends on the indications.
Due to the estriol content, the drug has restrictions for use - malignant estrogen-dependent neoplasms, lack of sexual activity in girls, endometriosis, and unclear nature of vaginal bleeding.
The choice between Laktozhinal or Gynoflor E suppositories should be discussed with your doctor due to possible contraindications.
Analogs of Laktozhinal suppositories
Laktozhinal suppositories are a French remedy for normalizing the vaginal microflora and reducing the recurrence of thrush, other vaginitis and vaginosis. The medicine belongs to the group of eubiotics and is available in vaginal capsules. The cost of packaging starts from 800 rubles.
Lactozhinal substitutes are suitable for those patients who are not satisfied with the price, composition, or have contraindications. When choosing an analogue, read the instructions for use and consult a gynecologist.
Lactoginal or Trioginal
Triozhinal is an analogue of Lactozhinal and Gynoflor E. The drug consists of three components - estriol and lactobacilli as Gynoflor E, gestagen. The last component is necessary for the colonization of the vagina with Doderlein's bacillus, which maintains the constancy of the vaginal microflora and prevents the development of infections.
Triozhinal is not sold freely from pharmacies. When choosing this analogue, consult your doctor for a prescription.
Laktozhinal suppositories are an over-the-counter remedy for restoring vaginal microflora. The analogue is used for atrophic vulvovaginitis caused by estrogen deficiency. In most cases, Laktozhinal is prescribed due to its safety, minimal number of restrictions and adverse reactions.
Analogues of Lactozhinal have a similar effect; they differ in indications, contraindications, mechanism, and composition. Which is better depends on each case individually. To prevent infections from becoming chronic, consult your doctor about options for replacement and full therapy.
Lactozhinal
Compound
The capsule contains 341 mg of lactobacilli . Auxiliary components: magnesium stearate and lactose monohydrate. The shell contains 98 mg of gelatin .
Release form
Translucent, gelatin capsules for vaginal administration. Inside the capsules there is a brownish powder without a specific odor. One clear glass bottle contains 14 capsules.
pharmachologic effect
Laktozhinal suppositories help restore the vagina's microflora after the use of antibiotics . The active substance is eubiotic and contains non-spore-forming, anaerobic rod-shaped bacteria. Lactobacilli are obligate flora and are found in certain quantities in the intestines, vagina, mouth, and vulva.
When the mucous walls of the vagina are colonized by living lactobacilli, an environment is created that is similar to the physiological one that is natural for a woman. The active substance has a peculiar antagonistic activity against certain bacteria (opportunistic, pathogenic):
Pharmacodynamics and pharmacokinetics
The gelatin-containing shell, when inserted into the vagina, quickly dissolves, releasing a lyophilized live culture with a high content of lactobacilli. It has been experimentally proven that within a few hours after administration, Lactobacillus normalizes pH and helps restore normal vaginal microflora.
Indications for use
The drug is prescribed to restore vaginal flora :
- before planned surgical interventions in gynecology;
- after prescribing antibiotics to treat bacterial vaginosis ;
- before caesarean section ;
- pregnant women at risk for vaginal pathology.
Contraindications
- thrush (candidiasis of the vagina and vulva);
- individual hypersensitivity;
- age up to 18 years.
Side effects
Rarely, vaginal discharge increases. Possible redness of the genitals, burning and other allergic responses . If other negative reactions occur, it is recommended to contact your doctor and stop taking Laktozhinal suppositories for a while.
Instructions for use (Method and dosage)
Capsules are administered only intravaginally . It is not allowed to take the medication internally.
Instructions for use: to quickly dissolve the gelatin capsule, it is recommended to pre-wet the capsule with water before inserting it into the vagina.
Treatment of bacterial vaginosis, restoration of one’s own flora after therapy with antimicrobial agents: 1 capsule per day (14 days) or 1 capsule twice a day (7 days).
Before planned surgical interventions, in prenatal preparation, administer 1 capsule twice a day. The course lasts 7 days. Additional comprehensive treatment is recommended. Dosing and correction of the treatment regimen is carried out by the attending physician, taking into account the dynamics of the course of the underlying disease and concomitant pathology.
Overdose
Cases have not been registered or described in the relevant literature.
Interaction
No significant clinical interactions have been reported. Simultaneous antiviral therapy and treatment with antibacterial agents are allowed.
Terms of sale
Storage conditions
Mandatory temperature control - up to 25 degrees. It is necessary to limit the access of children to the capsules.
Best before date
special instructions
After intravaginal administration, the capsules completely dissolve and do not leave stains on laundry or a specific odor. It is recommended to simultaneously prescribe immunomodulators to quickly restore your own flora. The medication can only be prescribed to women over 18 years of age.
Analogues of Laktozhinal
Medicines with similar pharmacological effects:
Structural analogues of Laktozhinal are not available. It is not allowed to independently replace the medication with analogues; it is recommended to fully follow the recommendations of the treating doctor.
During pregnancy (and lactation)
The drug can be used during pregnancy . Cessation of lactation for the period of therapy is not required. On the forums of expectant mothers, the drug is quite actively discussed, because... often prescribed by gynecologists during pregnancy. Reviews of the medication during pregnancy are positive; no side effects are noted.
Reviews about Laktozhinal
Evaluating posts on patient forums, we can conclude that reviews of the capsules are very different. Many users indicate a fairly rapid effect of treatment: the unpleasant symptoms of candidiasis disappear within the first days of therapy. Some patients were unable to fully evaluate the eubiotic, because it was prescribed for prophylactic purposes, and no particular effect was noticeable. During pregnancy, the drug is prescribed before planned surgical interventions, and reviews of Lactozhinal indicate that the capsules are well tolerated and there are no adverse reactions during the entire treatment period.
Laktozhinal price, where to buy
You can buy Laktozhinal suppositories in almost all pharmacy kiosks. The price depends on the pharmacy chain and sales region. For example, you can buy Laktozhinal in Moscow for 500 rubles, and in Kyiv for 220 UAH.
Analogues of Lactozhinal
If you experience intolerance to the main and auxiliary components, the impossibility of purchasing an expensive product, unavailability in the nearest pharmacies and other factors, check out the analogues of Lactozhinal capsules.
List of analogues cheaper with prices and country of origin
Analogue | Price, in rubles | Manufacturer country |
Lactozhinal | from 800 | France |
Genferon | 300-750 | Russia |
Ecofemin | 550-850 | Denmark |
Terzhinan | 400-650 | France |
Lactonorm | 450-700 | Russia |
Vagilak | 650-900 | Denmark or Croatia |
Lactagel | 650-900 | Sweden |
Gynoflor E | 600-800 | Germany or Switzerland |
Trioginal | France | 800-1100 |
Genferon
An analogue cheaper than Lactozhinal is the combined drug Genferon. The medicine consists of interferon, benzocaine and taurine. It has a wide spectrum of action - anti-inflammatory, immunomodulatory, antibacterial, antiviral, local anesthetic.
For the treatment of vaginal infectious and inflammatory diseases, it is available in dosages of 250 and 500 thousand IU. The course of treatment is determined by the doctor. For acute conditions, suppositories are administered intravaginally twice a day for 10 days, for chronic infections - every other day for 1 to 3 months.
Ecofemin
A drug for restoring vaginal microflora Ecofemin is based on lactobacilli acidophilus. The analogue is not used for thrush and individual intolerance. The course of treatment is 6 days, vaginal capsules are inserted into the vagina in the morning and evening.
The Russian analogue of Ecofemin is Acylact suppositories, also based on lactobacilli acidophilus. There are differences in application - the substitute is inserted into the vagina twice a day for 5-10 days.
Terzhinan
An analogue of Laktozhinal suppositories is Terzhinan vaginal tablets, available with a doctor’s prescription. It is a multi-component product and provides a range of therapeutic effects:
- antibacterial;
- antifungal;
- anti-inflammatory;
- antiexudative;
- antiallergic;
- antiprotozoal.
Additionally, the analogue constantly maintains the pH of the vagina and the integrity of the mucous membranes. Can be used by pregnant women as prescribed by a gynecologist.
Laktogin
Instructions for use:
Laktogin is a drug that belongs to the group of probiotics and is intended to restore normal vaginal microflora. In 2008, its trade name was changed, and now this drug is called Vagilac.
Release form and composition of Laktogin
Laktogin is available in the form of capsules and suppositories. Each capsule contains 10 9 lactobacilli Lactobacillus reuteri RC-14 and Lactobacillus rhamnosus GR-1. There are 15 capsules in a package.
Laktogin suppositories also contain live strains of lactobacilli Lactobacillus reuteri RC-14 and Lactobacillus rhamnosus GR-1, as well as starch, cellulose, dextrose and other excipients.
Pharmacological action of Laktogin
The instructions for Laktogin note that this drug contains a unique combination of lactobacilli isolated from the urogenital tract of absolutely healthy women. These bacteria colonize the vagina and begin to produce lactic acid, hydrogen peroxide and other biologically active substances that protect against various pathogenic bacteria. As a result, oral administration of capsules or local use of Laktogin suppositories contribute to the creation of an acidic environment in the vagina (pH 3.8 - 4.5), necessary for the functioning of normal vaginal microflora and destructive for pathogenic microorganisms.
According to reviews, Laktogin very quickly eliminates itching and burning in the perineal area, a feeling of discomfort and other unpleasant signs of bacterial vaginitis. In addition, the use of Laktogin reduces the likelihood of a subsequent relapse of the disease by almost 80%.
Indications
According to the instructions, Laktogin can be used by women over 18 years of age in the following cases:
- For the treatment of vaginal dysbiosis, both as part of complex therapy and as monotherapy;
- For the treatment of chronic and subacute infectious and inflammatory diseases of the female genital area;
- During and after treatment with cytostatics, antibiotics, antiviral, antifungal drugs and corticosteroids;
- For prenatal preparation in pregnant women;
- For the treatment of hormonally dependent and senile colpitis;
- During the preparation of a woman for gynecological operations and diagnostic procedures, incl. and before installing an intrauterine device.
Contraindications
According to the instructions, Laktogin should not be used by women who have increased individual sensitivity to any of the components of this drug.
Side effects
In rare cases, when using Laktogin suppositories, local allergic reactions may occur, manifested by a feeling of burning, itching and discomfort in the genital area. In this case, the instructions for Laktogin recommend that women switch to oral administration of this drug in capsule form.
Method of use of Laktogin and dose
To normalize vaginal microflora, take one capsule of Laktogin per day. When treating inflammatory diseases of the vagina, the dose increases and is two capsules per day. Laktogin should be taken on an empty stomach or two hours after a meal with plenty of water.
Laktogin suppositories are inserted at night after vaginal douching.
The use of Laktogin, according to reviews, leads to the rapid restoration of vaginal microflora.
Conditions for storage and release from pharmacies
Laktogin should be stored in a cool, dry and dark place out of the reach of children. The shelf life is one and a half years. Laktogin capsules and suppositories are available from pharmacies without a doctor's prescription.
Laktogin
Laktogin is a drug that is part of the group of probiotics, indicated for restoring normal microflora in the vagina.
Release form, composition and packaging
The drug Laktogin is produced:
Active ingredients: in 1 capsule – 109 lactobacilli Lactobacillus reuteri RC-14 and Lactobacillus rhamnosus GR-1.
There are 15 capsules in a cardboard package.
Active ingredients: 1 suppository contains live strains of lactobacilli Lactobacillus reuteri RC-14 and Lactobacillus rhamnosus GR-1 directly.
Auxiliary components: dextrose, cellulose, starch.
pharmachologic effect
Laktogin contains a combination of lactobacilli extracted from the urogenital tract of exclusively healthy women. These bacteria actively colonize the vagina and begin to produce hydrogen peroxide, lactic acid, and other biologically active substances, the properties of which include protection against pathogenic bacteria.
Local use of suppositories or taking capsules contributes to the creation of an acidic environment in the vagina (pH 3.8 - 4.5), which is extremely necessary for the normal functioning of the vaginal microflora and is quite harmful to pathogenic microorganisms.
Laktogin very quickly eliminates itching and burning, a feeling of discomfort and other undesirable signs of bacterial vaginitis in the perineal area.
The use of Laktogin reduces the likelihood of disease relapse by almost 80%.
Indications for use
Main indications of the drug Laktogin:
- therapy for vaginal dysbiosis, as an independent treatment and as part of complex therapy;
- infectious and inflammatory diseases of acute and chronic nature of the genital area regarding women;
- colpitis – senile and hormonally dependent;
- the period of treatment with corticosteroids, antibiotics, cytostatics, antiviral and antifungal medications, as well as upon completion of treatment;
- prenatal preparation of pregnant women;
- the period of preparation for diagnostic procedures, gynecological operations, before installing an intrauterine device.
It must be taken into account that Laktogin should not be used by women under 18 years of age.
Contraindications
The drug Laktogin has one contraindication:
Directions for use and dosage
According to the instructions, Laktogin is recommended to be taken on an empty stomach or 2 hours after a meal, with sufficient quantity of water. Laktogin suppositories are inserted at night, after mandatory cleansing and douching of the vagina.
Recommended dosages per day:
- one capsule – to normalize vaginal microflora;
- two capsules – therapy of inflammatory diseases of the vagina.
Side effects
Usually, the use of both forms of Laktogin is well tolerated, but in rare cases the following are possible:
In the genital area:
As a rule, these side effects are inherent after the use of suppositories, and in the case of these phenomena, it is advisable to switch to oral administration of the drug.
Analogues of the drug
Analogues of the drug Laktogin are: Mastofit, Folio, Neocardil, Inoltra, Artichoke Extract, Lymphosan, Vijaysar, Atlantinol, Hepana, Vijar, Biocalcevit, Cardioform, Bifilact Extra, Gotu Kola, Pineapple Extract, Mumiyo Shilajit, Todikamp, Brudi Plus, Uroprofit, Fortege , Endorm, Vezilyut, Lecithin, Miron, Noteo, Endocrinol, Aloe Compound, Estrovel, Lactogon, Leptaden, Turboslim Day, Lamifaren, Sealex, Turboslim Night, Desyatil Altai and others.
Storage conditions
The drug Laktogin is kept in a place inaccessible to children, sufficiently cool, dark and dry, at a storage temperature of no more than 25 ° C.
Shelf life, adhering to the storage requirements specified in the instructions, is 1.5 years.
In the pharmacy chain, Laktogin is sold without a doctor's prescription.
Lactozhinal or Lactonorm - which is better?
If the pressing question is how to replace Lactozhinal suppositories if they are not available in pharmacies, are expensive or have contraindications, then Lactonorm vaginal capsules are suitable. Their price is up to 2 times lower. An analogue is produced in Russia, based on strains of acidophilic lactobacilli that do not enhance the growth of candida fungus.
The analogue Lactonorm is approved for use in childhood and adolescence and has positive reviews. Use 1-2 vaginal capsules for 7 days, depending on the purpose - treatment or prevention.
The components included in the analogue normalize and maintain the vaginal microflora and regulate balance.
When choosing between Lactozhinal and Lactonorm, pay attention to the indications and contraindications. Medicines differ in composition, country of origin and price.