Nail fungus varnish Loceryl is a good antifungal agent that helps get rid of fungus that has affected the nail plates on the hands and feet. At an early stage, when minor areas of the nail are infected with the fungus, it is used as the only means of treatment. In more advanced cases, varnish is an important component of complex antimycotic therapy.
Lac Loceryl has long proven its effectiveness in the fight against nail fungus
The active ingredient of Lotseryl varnish is Amorolfine. It destroys dermatophytes, as well as mold and yeast fungi. The concentration of Amorolfine is 50 mg per 1 ml of medication. In addition, the composition includes a copolymer of methacrylic acid, as well as triacetin, butyl acetate, ethyl acetate, and ethanol.
After applying the antifungal varnish, it hardens and covers the surface of the nail plate. The active substance penetrates deep into the nail. 7-10 days after the 1st application, its concentration becomes maximum. Antifungal varnish has a fungistatic as well as fungicidal effect on fungi. This medicine destroys them by destroying the cytoplasmic membrane and disrupting biosynthesis processes.
Loceryl varnish is available in bottles of 2.5 and 5 ml. In addition to the varnish, the package contains a set of accessories for preparing nails for the procedure. It consists of 5 or 10 spatulas intended for applying the product, 15 or 30 files and 30 or 60 cotton swabs soaked in alcohol. The latter are necessary for high-quality disinfection of nail plates and instruments.
Antimycosis nail polish Loceryl is prescribed for the treatment of onychomycosis on the nails of the hands and feet, in order to prevent the development of this disease. It is suitable for adults and children over 12 years old.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Loceryl is an antifungal external drug. The drug exhibits fungicidal and fungistatic effects, which are caused by the destruction of the cytoplasmic membrane of the fungal cell by blocking the synthesis of sterols . of ergosterol decreases , atypical non-planar sterols . Has a wide spectrum of action.
Inhibits both common and rare types of fungi that cause nail lesions:
- yeast fungi of the genera Malassezia (Pityrosporum), Candida, Cryptococcus;
- dermatophytes of the genera Microsporum, Trichophyton, Epidermophyton;
- fungi of the genera Fonsecaea, Cladopsorium, Wangiella (family Dematiaceae);
- molds of the genera Scopulariopsis, Alternaria, Hendersonula;
- dimorphic fungi of the genera Coccidioides, Histoplasma, Sporothrix.
Pharmacokinetics
After application to the nail plate, it penetrates into the nail bed. The therapeutic concentration remains for 10 days even after the first use.
Absorption into the systemic circulation is negligible.
Medical pedicure
Hardware pedicure is another method to delay the development of a fungal infection. This procedure consists of polishing the nail with a cutter with a diamond or metal attachment. The device also removes the stratum corneum of the skin. Using a milling cutter, if necessary, remove the nail plate down to the bed. Then the nutrient medium for the fungus will disappear, and as a result the infection will recede.
In case of severe lesions, the nail plate is completely removed under anesthesia. However, during the procedure, the matrix (the area of epithelium under the root of the nail plate) is damaged, because of this the new nail does not adhere to the skin, and its shape will be incorrect.
Instructions for use of Loceryl (Method and dosage)
The instructions for Loceryl indicate that nail polish should be used externally, applying it to nails affected by fungus up to two times a week according to the scheme below:
- Before using the drug, you should, if possible, remove the affected areas of the nail plate using a nail file, which is included in the kit;
- then the surface of the nail plate should be cleaned and degreased with a swab from the kit soaked in alcohol (a similar treatment with a file and swab must be carried out each time before using the medicine);
- the next step is to dip the spatula into the bottle of varnish and remove it without touching the neck of the bottle (it is forbidden to remove excess product on the neck of the bottle);
- Nail polish Loceryl is applied to the affected nail over the entire surface using a spatula, repeating this procedure for each affected nail;
- then close the bottle tightly immediately after use;
- the varnish is allowed to dry (this usually happens within 3 minutes);
- Wipe the spatula with the used tampon, avoiding contact between the nail plates and the tampon, and throw it away;
- Treatment is continued until the affected area is healed and the nail is regenerated.
The average duration of treatment for fingernails is 6 months and for toenails – 1 year.
Contraindications and side effects
The use of varnish against fungus Loceryl is tolerated normally by patients. Side effects occur in isolated cases. These include a burning sensation after applying the product. It goes away quickly.
Contraindications to the use of medicinal varnish:
- pregnancy period;
- lactation;
- hypersensitivity to the components included in the drug;
- age up to 12 years.
Loceryl is compatible with other drugs.
During pregnancy, the use of varnish is prohibited
special instructions
Files that were used to process diseased nail plates should not be used to manipulate healthy nails.
Persons working with organic solvents should wear impermeable gloves to protect polished nails.
During treatment with the drug, you should avoid using artificial false nail plates and do not use cosmetic varnish.
The tampon contains a highly flammable component.
It is necessary to avoid penetration of varnish into the ears, eyes and mucous membranes.
Persons with conditions predisposing to the appearance of fungal infections of the nail plates ( diabetes mellitus , peripheral circulatory disorders, immunodeficiencies ), as well as persons with or damaged nails or nail dystrophy, should consult a doctor before using the drug.
Pharmacy drugs
In the initial stages of onchomycosis, when the first symptoms appear (itching, burning between the fingers, discoloration of the nail), safe herbal medicines are used. But over time, when a fungal infection makes its way inside the nail, it is necessary to use systemic medications.
But as mentioned earlier, they are not recommended for use during lactation, as the likelihood of negative effects of medications on the baby increases. That is why restraining therapy is relevant for nursing women, which inhibits the development of fungal infection. After breastfeeding, it will be possible to carry out full treatment using medications with systemic action.
When breastfeeding, it is allowed to use local drugs, which also accumulate in the tissues of the body, but their concentration is low (unlike systemic medications). Antifungal drugs are produced in the form of ointments, creams, gels, aerosols, and varnishes.
The most popular medications for lactating women are Loceryl (5%) and Miconazole. Loceryl based on amorolfine is used for local treatment of nail fungus and is available in the form of varnish. The drug is effective against candida, trichophyton, microsporum and others. The drug stops the development of the fungus, after which it dies.
Breastfeeding mothers can treat fungus with Miconazole only after the approval of a doctor, since the instructions indicate that the drug is contraindicated during pregnancy and lactation. For external use, a spray based on miconazole is prescribed, which is active against fungi and bacteria. The drug stops the development of pathogenic microorganisms, as a result they die.
Loceryl's analogs
Level 4 ATX code matches:
Mikonorm
Undecin
Gentian violet
Zinkundan
Exoderil
Exiter
Batrafen
Lamisil Dermgel
Lamisil Uno
Lamisil
Salicylic acid
Salicylic ointment
Keto Plus
Exifin
Fungoterbin
Mycoseptin
Thermikon
Nitrofungin
Sulsena
Baziron AS
Batrafen (varnish, spray), Oflomil Lac, Amorolac, Mikolak, Bifosin (spray), Demikten (varnish), Terbix (spray), Lamisil (cream, spray), Lamifast (cream), Kanespor (ointment), Fungoterbin (Russian equivalent) in cream form). The price of Loceryl analogues is noticeably lower than the price of the described drug.
Recommendations from mycologists
Restraint therapy involves following the following rules:
- To prevent the infection from spreading to the newborn, the mother needs to wash and dry her breasts before each feeding. In addition, do not forget to keep your hands clean; wash them with antibacterial soap before picking up your baby.
- Change your socks daily and only wear them on clean, dry feet. Give preference to cotton products. During hot weather, change your socks at least 2 times a day. It is recommended to boil and iron the product before the next use.
- Use only personal towels separately for your face, body, and legs. Wash them only in hot water (temperature at least 90°).
- It is recommended to change things daily.
- If you wash in the bathroom, clean it after yourself using disinfectants. Don't forget about the rug, which needs to be washed in hot water.
- For pedicures, use personal tools that are prohibited for others to use. After treating your nails, disinfect the set and bath.
- Avoid visiting a bathhouse or swimming pool, as it is easy to catch fungus in such places.
- Disinfect shoes once every 30 days using special preparations. Don’t lend your shoes to anyone, don’t wear someone else’s.
- It is recommended to purchase a steam cleaner and clean with it once every 7 days. This way you will destroy fungus, mites, worms and other parasites that live in carpets or furniture.
Thus, for hepatitis B, restraining therapy is indicated; discuss the treatment plan with your doctor.
Follow the rules described above to prevent the fungus from spreading and infecting your loved ones. After the end of lactation, be sure to carry out systemic treatment, even if the symptoms of the fungus are not noticeable. It is found in the nail plate, and its spores penetrate the bloodstream. This can lead to skin and hair infection. Subscribe to our VKontakte group
Reviews about Lotseril
Reviews of Lotseryl varnish on forums are often replete with a large number of negative reviews of Lotseryl nail fungus varnish. Reviews from doctors also indicate that the drug is often ineffective. The greatest dissatisfaction is caused by cases of complete lack of therapeutic effect at a high price for this varnish against nail fungus.
Varnish Batrafen or Loceryl - which is better?
The difference between Batrofen or Loceryl is that they include different active components, although their mechanisms of action are similar. Both products are produced in the form of a varnish, and both drugs have approximately the same structure of reviews, indicating the absence of a therapeutic effect in approximately half of the cases. The price of Batrafen is approximately 2 times higher than the price of Loceril. The choice should be made based on doctor's prescriptions and economic considerations.
Tactics for treating fungus
If you suspect a fungus in a nursing mother, you should visit a doctor, because self-medication is fraught with dangerous consequences. A mycologist or dermatologist will conduct an examination and determine the nature of the infection.
The body of a lactating woman is subjected to intense stress, which is accompanied by hormonal imbalance and deficiency of nutrients. These disorders can provoke many dermatological diseases, and therefore laboratory tests are indispensable. The doctor will take a scraping from the nail plate to determine the culture of the fungus, and then determine a treatment plan.
Many doctors are of the opinion that it is not worth treating fungus during lactation. They explain this by the fact that onchomycosis is less dangerous for infants than medications. But if a woman still insists on treatment, then it is carried out under the supervision of a doctor and strictly according to the scheme that he has determined.
Lotseril price, where to buy
The price of Lotseryl nail polish 2.5 ml in Russia is 1300-1500 rubles. Buying Loceryl in Moscow or St. Petersburg will cost approximately comparable amounts, falling within the above limits.
How much does it cost to buy the product in other CIS countries?
The price of Loceryl in Ukraine in the specified release form reaches 1,400 hryvnia. In Belarus, in Minsk and other cities, this antifungal varnish is not available for sale at all. The cost of 2.5 ml of nail polish against fungus in a pharmacy in Kazakhstan is 10,500-13,500 tenge.
Analogs of Loceryl in other forms of release (drops, ointment, tablets) are much cheaper and if you are on a limited budget, you should pay attention to them.
- Online pharmacies in RussiaRussia
LuxPharma* special offer
- Loceryl cream cream 20g
RUB 1,380 order
ZdravCity
- Loceryl nail polish 5% 5mlGalderma
RUB 1,475 order
- Loceryl nail polish 5% 2.5mlGalderma
976 rub. order
Composition of Loceryl and active ingredient
According to the instructions, 1 ml of the substance contains 50 mg of amorolfine and additional components of Loceryl: ethyl acetate, ethanol, triacetin, butyl acetate, methacrylic acid copolymer. 1 bottle of the drug contains 2.5 or 5 ml of the drug. In addition to the instructions, the kit includes a special disposable nail file, a spatula for applying varnish and swabs for treating the affected areas from contamination.
Amorolfine penetrates through the surface layers of the nail plate or epidermis to the site of inflammation, has an antifungal effect due to the ability to inhibit the synthesis of enzymes of pathogenic organisms. The anti-inflammatory effect is caused by stopping the production of anti-inflammatory enzymes; the activity of leukocytes in the lesion site decreases.
