Picamilon (Picamilonum) for children. Reviews, instructions for use, price

The child does not always grow and develop the way the parents would like. For various reasons, some children lag behind in the rate of growth and knowledge of the world around them. This may be due to pathologies in the nervous system.

Fortunately, today there are enough nootropic drugs that can solve the baby’s problems. One of these medicines is Picamilon for children, produced in the form of tablets or solution; we will now look at its instructions for use, and also get acquainted with parents’ reviews of this medicine.

Release forms and composition of the drug

Picamilon is a chemical structure consisting of the active substance 4-(pyridine-3-carbonylamino) butanoic acid or nicotinnyl-γ-aminobutyric acid.

Like other nootropics, Picamilon improves brain function, overall productivity, concentration, motivation and memory. In addition, it significantly reduces feelings of stress, anxiety and depression.

Available in tablets of 30 and 60 mg, packaged in polymer bottles. Talc, starch are present as fillers, and glucose and magnesium carbonate are also contained as a food additive.

Compound

The main active ingredient of Picamilon is nicotinoyl-GABA, or nicotinoyl-gamma-aminobutyric acid. In addition to it, the tablets also contain:

• starch;
• sucrose;
• magic hydroxycarbonate hydrate;
• stearic acid;
• talc;
• calcium stearate.

These substances are necessary to enclose the required amount of the active component in the form of a pill, and are also responsible for the shelf life of the drug.

The solution for injection contains the active substance in the appropriate concentration; a volume of two milliliters is achieved using water for injection.

Pharmacological properties

Picamilon for children, reviews of which are mostly positive, is a nootropic drug that has a specific effect on certain brain functions. It is intended to stimulate tissue metabolism and improve memory.

The action of Picamilon is based on a synthetic combination of gamma-aminobutyric acid (GABA) and niacin. The first is responsible for reducing the excitability of neurons, and the second acts as a strong vasodilator, and both substances play a certain role in the metabolism of nerve cells.

The drug acts as a nootropic supplement combining GABA and niacin (vitamin B3). Gamma-aminobutyric acid and its derivatives increase the brain's resistance to oxygen starvation, enhance the absorption of sugar cells and the formation of proteins.

The positive effect of nootropics on the body is to improve vascular blood flow in the brain. This occurs under the influence of niacin, which dilates blood vessels.

Positive properties of Picamilon:

• increases productive brain activity;
• lowers the level of lactates in the connective tissue of the brain;
• prevents hypoxia;
• stimulates the processes of excitation and inhibition occurring in nerve tissues;
• reduces the severity of symptoms of neurological diseases.
• increases the intensity of mental activity and learning ability.

What is it prescribed for?

It is recommended to take the medicine if you have the following ailments:

• Migraine.
• Cerebral circulatory disorders.
• Developmental delay.
• Enuresis.
• Disturbances in the functioning of the urethra.
• Asthenia.
• Depressive disorders.
• Stress, neuroses.
• Decreased performance.
• Emotional instability, anxiety, restlessness.
• Mental and physical stress.
• Acoustic neuritis.

Pharmacodynamics and pharmacokinetics

Picamilon is transported across the blood-brain barrier via a special niacin analogue pathway. It then hydrolyzes (reacts with water) and breaks down into the neurotransmitter GABA and niacin. Therefore, the effects produced by Picamilon are typical of higher levels of GABA and niacin.

Niacin was chosen as a carrier due to its valuable pharmacological properties, low toxicity and high bioavailability. The combination of niacin and GABA in the same molecule increases the activity of each component.

Once the chemical picamilon is broken down, the body begins to work primarily with niacin. It improves the pharmacokinetic properties of GABA and allows the acid to enter the brain.

GABA is an amino acid that acts on the receptors of biologically active chemicals, through which impulses from a nerve cell are transmitted between neurons. All nerve cells connect to each other using chemical and electrical synapses.

At chemical synapses, information is transmitted by neurotransmitters, or intermediaries between neurons, which can accelerate or inhibit the transmission of information by neurons. Many drugs act on the release of mediators and can correct their disturbed balance in mental disorders.

GABA is considered an inhibitory neurotransmitter that is used by the brain to relax and prevent overstimulation. These effects are described as anxiolytic, meaning they reduce anxiety and stress.

As a precursor to niacin, Picamilon helps improve energy metabolism in the brain and supports healthy neurons. Niacin, as part of the vitamin B complex, has a number of functions in both the nervous system and the gastrointestinal tract.

The effect of niacin is to dilate blood vessels in the brain, increasing cerebral circulation. Consequently, the supply of nutrients, glucose, and oxygen to the brain increases. The drug through niacin can lead to an increased level of mental concentration and endurance.

This improves overall brain function because this increase in blood flow leads to improved energy metabolism in the brain cells. Picamilon, by increasing blood flow, has a detoxifying effect on neurons, so a large number of toxins that accumulate in cells are removed at a faster rate.

N-nicotinoyl-g-aminobutyric acid sodium salt - the active substance - is odorless white powder crystals, highly soluble in water. Despite its chemical origin, the active substance does not have a toxic or carcinogenic effect on the human body. The residual level of the active substance in the body is high, ranging from 50–80%.

It is quickly and almost completely absorbed and remains in the tissues for a considerable time. Easily overcomes the blood-brain barrier due to free non-ionized molecules. A large amount of the drug enters the organs that are intensively supplied with blood.

Distribution in muscle tissue, adipose tissue, and brain occurs evenly. Does not take part in metabolism, is excreted unchanged through the kidneys, the half-life in the blood plasma is 0.5 hours.

Picamilon - video

In this video, a specialist gives a detailed description of the drug Picamilon for children and its scope of application. Tells what effect the drug has and how effective it is in individual cases.

Picamilon is a nootropic drug that stimulates metabolic processes in the neurons of the brain and central nervous system. It is prescribed for a fairly wide range of pathologies in both children and adults. However, this is a fairly serious drug, so it is very important to strictly follow the recommendations for its use, dosage and duration of the course prescribed by your doctor. Only in this case the medicine will be beneficial and will not cause harm.

Has your child ever been prescribed Picamilon? What symptoms or pathologies was this associated with? Have you received a positive result from the treatment? Have there been any adverse reactions? Share your experience in the comments, this will guide the mothers and fathers of those babies who were prescribed this remedy for the first time. Healthy children and good mood to you!

Indications for use

Picamilon is prescribed to children who have a minor neurological problem, ADHD, or mild dysarthria. It is used in complex therapy. In pediatric neurology, nootropics are widely used to treat children with postnatal encephalopathy, psychomotor disorders, and delayed speech development.

The drug helps:

• get rid of stress, anxiety and depression;
• increase motivation;
• improve mental clarity;
• increase attention;
• cheer up;
• develop memory;
• increase intellectual and logical abilities.

Picamilon is used in the following cases:

• neurological disorders;
• memory restoration after traumatic brain injury;
• migraine prevention;
• childhood enuresis.

Picamilon does not cause muscle relaxation, drowsiness or lethargy.

Reviews from parents about the use of Picamilon for children

Olga, 27 years old:

We had problems when the child went to kindergarten. He became nervous, aggressive, completely inattentive. We went to the doctor and were advised to take Picamilon. A monthly course was prescribed. But the result was obvious within a week. The baby became calmer, stopped bullying the children in the group, and the teacher began to praise. Either I got used to the situation, or the drug really helped, but in the end everyone is happy - me, the baby, and the other kids.

Svetlana, 23 years old:

Our child started screaming at about six months. Until your lips are blue, constantly, for no reason. We went to the doctors and were first prescribed Elkar for infants. The child became calmer, but sudden attacks of hysterics continued. Then we were prescribed Picamilon, registered as a hospital for a week, the medicine was injected there first, then we just came for the injection. After a couple of days, the baby became noticeably calmer, and after a week he stopped screaming for no reason at all. So the drug is effective, I highly recommend it.

Elena, 26 years old:

Since birth, my baby has been, so to speak, “nervous.” For some time we were regularly prescribed B vitamins for children. And at the age of 4, the doctor decided to try Picamilon tablets. We drank one every day for about a month and a half. The baby began to do well in kindergarten, his mood stabilized, and the hysterics and attacks of aggression stopped. The course was repeated twice on the recommendation of the same doctor, with a break of two weeks each time. The only negative is that in the first week the child periodically had a headache, so take this side effect into account.

Ivana, 22 years old:

We had complications during childbirth and the child was diagnosed with hypoxia. Immediately after birth, the child was given IV drips with Picamilon to avoid serious developmental complications. Then, from about a year old, they periodically prescribed the best vitamins for children, I don’t even remember all the names. Now we are three, and neither I nor the doctors observe any developmental delays. And it seems to me that this is precisely thanks to those IVs that were put in immediately after the injury.

Evgeniya, 32 years old:

I never observed developmental pathologies in my son as such, but in the second grade he suddenly began to lag behind in all subjects, he quickly got tired, they even decided to temporarily stop training - he has been training in the wrestling section since he was 6 years old. The doctor recommended taking a course of stimulants. Recommended by Picamilon. I was concerned that it was a nootropic, but we decided to try it. Literally on the second day, we got the whole list of adverse reactions, so I categorically do not recommend it. As a replacement, we were prescribed Cogitum for children. It’s a completely different matter, literally two weeks of the course, and the child began to come to life. As for Picamilon, I advise you to think twice about whether your child really needs a nootropic with a tranquilizer effect.

Instructions for use, dosage

Picamilon is prescribed to children in small doses, 10–20 mg. Starting from the age of 10, tablets containing a large dose of GABA, 50 mg, are prescribed. The intake is independent of the time of meal; the tablets should be taken with plenty of water, tea, juice or milk.

Since the effect of Picamilon lasts from 4 to 6 hours, the best results will be achieved if the dose is divided into 2-3 times during the day.

Childhood enuresis:

• 20 mg per day for children 3-10 years old;
• 20 mg per day for children over 10 years of age.

For asthenia, neurotic reactions:

• 20 mg per day for children from 3 years to 10;
• 20 mg per day for children over 10 years of age;
• 50 mg per day for adolescents over 15 years of age;
• Duration of treatment: at least 30–40 days.

Treatment of depressive conditions, increasing the child’s performance:

• 40 mg per day for children from 3 to 10 years old;
• 60 mg per day for children 10 years old;
• Duration of treatment is from 30 to 55 days.

Doctors do not recommend taking Picamilon for preventive purposes, especially for children. Since it affects the functioning of brain structures, it can harm the process of strengthening neural connections in the brain. It is advisable to use it in case of severe neurological disorders and strictly as prescribed by a doctor.

If children suffer from acute respiratory viral infections or viral infections, it is not recommended to use the supplement until complete recovery.

At what age is it allowed to take

Picamilon is a specialized drug. It is safe enough that doctors can prescribe it from birth if necessary. But there must be strong evidence for this. Children under 3 years of age most often use the drug by injection. For a child over this age, tablets with a minimum concentration of the active substance are quite suitable.

Despite the relative safety of the drug, it should be understood that this is not a vitamin. This is a nootropic drug that directly affects brain activity and the performance of the nervous system. Therefore, it can only be used as prescribed by a doctor, regardless of the age of the young patient.

Side effects

Picamilon for children (reviews about the drug are mostly positive due to the absence of external symptoms) is well tolerated and effectively helps normalize the functions of the nervous system.

In rare cases, gastrointestinal disorders are present:

• nausea;
• vomiting reflex;
• diarrhea;
• stomach pain.

Sometimes neurological reactions occur:

• fatigue;
• headache;
• lethargy;
• systemic dizziness.

allergic reactions

• rashes;
• redness on the skin of the face;
• itching

In all of the above cases, reduce the dosage or stop taking the drug.

special instructions

Doctors say that the interaction of the drug Picamilon with other drugs is negative.
There is a high probability of complications. It is better to store the medicine in a dark place.

It should not be used by children under three years of age due to the possibility of side effects..

The medicine in the form of ampoules is used only under the supervision of a doctor. It is recommended to treat children with tablets. The duration of taking the drug is determined by the doctor.

With regular use of the drug, the child's condition will improve significantly. Efficiency and endurance will increase. The child will get rid of mental stress, and blood circulation in the brain will be normalized.

Picamilon should be taken strictly according to the instructions; you cannot increase the dosage on your own . Only a specialist can do this.

Drug interactions

Reviews from doctors indicate that taking Picamilon is safe with other supplements or nootropics that are given to children. The combination of Picamilon and Oxiracetam, Aniracetam supplements enhances the effect of the drug. If it is combined with valerian, the calming properties of Picamilon may also be enhanced.

Each drug that modulates GABA receptors can alter the action of Picamilon:

• Barbiturates.
• Benzodiazepines.
• Non-benzodiazepines (psychoactive drugs similar to benzodiazepines).

It is not advisable to take Picamilon together:

• with high dose aspirin;
• uricosuric agents.

Scope of application and effect

For patients prescribed the drug Picamilon injections, the instructions for use must be followed without fail. Moreover, treatment can only be started on the recommendation of the attending physician. The drug has the following effect on the patient’s body:

• nootropic;
• antiaggregation;
• antioxidant.

The patient experiences a positive tranquilizing and psychostimulating effect. Thanks to the action of the active component, metabolism in brain tissue is normalized and blood flow improves. At the same time, people taking the drug experience the following effects:

• minimizing headaches and migraine symptoms;
• memory activation;
• increased physical and mental activity;
• sleep restoration;
• reduction of nervousness and increased anxiety;
• positive influence in the process of restoration of motor and speech functions;
• reducing the negative effect of ethanol on the central nervous system
• activation of blood flow in the area of ​​the retina and optic nerve.

Absorption of substances occurs in full. This process is quite fast. Penetration into the body occurs through the BBB, and then long-term retention of components in tissues is observed, ensuring bioavailability at the level of 50-88%. Excretion is carried out in the same form without changes through the kidneys. Time for half-life in urine is about an hour.

Analogs

Picamilon for children (reviews of which are mostly positive, although some consider it not very effective) is of great benefit in complex treatment. In addition to this drug, there are a number of similar means that achieve the same treatment effects.

Analogues containing the same chemical structure and active ingredients are called complete. Many drugs have different compositions, but are similar in indications. Some analogues differ from Picamilon in their therapeutic effect and method of administration. In any case, the prescription of the medicine or its analogue must be agreed with the doctor.

general characteristics

Nootropic drugs are used in the treatment of various disorders of the nervous system. They improve brain function and blood supply. Such agents increase the resistance of cells to hypoxia or increased stress. They improve intellectual functions, normalize sleep and mood.

Most often, Picamilon is prescribed for this purpose for children. Instructions for use, price, reviews - everything indicates its advantages over other means. Safer, with fewer side effects, but an effective drug costs only about 100 rubles. Therefore, this course of treatment is available to everyone.

This drug belongs to a group of drugs containing neuroamino acids. They are used for neuroses, cerebrovascular accidents, increased excitability, and sleep disorders. In addition to Picamilon, these are drugs such as Phenibut, Pantogam, Glycine.

The drug "Picamilon" is produced. It owns the rights to the production and manufacturing technology of the medicine. It is sold in pharmacies with a doctor's prescription. Available in small plastic jars of 30 or 50 tablets.

Price in pharmacies in Moscow, St. Petersburg, regions

Comparative table of drug prices in different regions of the country:

The low price of the drug is set due to its production in Russia. Picamilon is produced by Novosibkhimpharm OJSC. Drug code ATX - NO6BX.

In many pharmacies you can find Picamilon for intramuscular or intravenous administration, which can be used by children no earlier than 14 years of age. The price of this dosage form is slightly higher.

Doctors often prescribe Picamilon to children starting at 2 years of age. Judging by numerous reviews from parents, the drug has a positive effect on mental activity, stimulates speech development, and normalizes sleep. However, it should be remembered that its effect is aimed at cerebral circulation, which is why you should drink it only as prescribed by a doctor.

Picamilon price, where to buy

The medicine is available only by prescription, so it is impossible to purchase it at a pharmacy without an appropriate medical prescription. If you do not have a prescription for Picamilon, you can show the pharmacy employee the entry in your medical record indicating the prescription of the drug.

The cost of 20 g tablets in packs of 30 pieces is about 420 rubles. The cost of ten 2 ml ampoules in Russia is approximately 400 rubles.

You can buy 30 tablets in Ukraine for 40 hryvnia. Ten ampoules of injection solution will cost a patient from Ukraine approximately 90 hryvnia.

DETAILS: Points for placing leeches in urology

The price for tablets of 0.02 g, in packs of 30 pieces, in Russia is about 420 rubles. The same amount of the drug can be bought in Ukraine for 40 UAH. In Kyiv, the medicine will cost you 60 UAH, in Kharkov – 50 UAH.

In Russia, the price for 10 ampoules of 2 ml each is 400 rubles. The cost of the injection solution in Ukraine is 90 UAH for 10 ampoules (10% solution, 2 ml), in Kyiv – 120 UAH. You can buy the drug in Kharkov for 100 UAH – 10 ampoules.

The approximate price for Picamilon is: 30 tablets of 50 mg – 104 rubles, 30 tablets of 20 mg – 87 rubles, 10 ampoules of solution for intramuscular and intravenous administration – 129 rubles.

Now you know how and for what indications Picamilon should be given to children. The price of this drug is 420-450 rubles.

Most reviews about this medicine are positive. However, some patients did not find its effect very effective.

Despite the fact that this medication is not recommended for children under 3 years of age, many pediatricians still prescribe it to two-year-old children. According to parents, this product does not cause any allergic reactions. Moreover, it has virtually no side effects.

Parents are quite satisfied with the effectiveness of this medicine. After taking it, their children become much calmer. Their sleep is normalized, and in some cases, speech development is even stimulated.

As for doctors, they also speak well of this medicine. Doctors say that this drug should be used only after consultation with an experienced specialist.