Ringer's solution - composition, indications and instructions for use

Ringer's solution is used to treat various diseases; it is a drug that replaces blood plasma. This drug contains fast-acting components and is available in pharmacies with a prescription. A Ringer IV is not always prescribed during pregnancy, but only if the potential benefit to the mother outweighs the risk of side effects in the baby. The drug is used with caution during breastfeeding.

Composition of Ringer-Locke solution

Ringer is available in liquid dosage form. A colorless liquid of transparent consistency contains active and auxiliary substances. The auxiliary substance is water for intravenous injection. The components in distilled water that make up the Ringer's Acetate solution are selected with precise concentrations to provide the product with a plasma-substituting and perfusion effect. The IV solution contains inorganic salts and sodium bicarbonate as a buffer component to stabilize the acidity of the pH. Solution composition:

• sodium chloride;
• sodium bicarbonate;
• calcium chloride hexahydrate;
• potassium chloride;
• glucose.

Analogs

Ringer's solution has no structural analogues for the active substance. Presented below are analogues of the drug Ringer's Solution, in accordance with medical terminology, called “synonyms” - drugs that are interchangeable in their effects on the body, containing one or more identical active ingredients.

Analogues by pharmacological group (regulators of water and electrolyte balance in combinations): Acesol; Disol; Yonosteril; Quintasol; Methuselum; Sodium fumarate is complex; Neohemodesis; Plasma-Lit 148 aqueous solution; Plasma-Lit 148 with 5% Glucose; Hartmann's solution; Regidron; Ringer lactate; Ringer Lactate Viaflo; Ringer's acetate; Ringer's lactate with magnesium; Complex solution of sodium lactate Bieffe (Ringer's lactate solution); Sorbilact; Compound sodium lactate; Trisol; Hlosol. Source:

When selecting synonyms, consider not only their cost, but also the country of production and the reputation of the manufacturer.

Ringer's solution indications for use

The Latin name for the multicomponent solution is Solutio Rlnger-Locke. For each patient it is necessary to select its own dosage. The use of Ringer's solution as a hydrating drug is indicated for hyponatremia (when the concentration of sodium ions in the blood becomes below normal), hypovolemic shock (with a sharp decrease in circulating blood volume), non-respiratory acidosis (metabolic). In all these cases, disturbances occur related to the functionality of the circulatory system. Also, a Ringer dropper is used for conditions such as:

• thermal injuries (shock, frostbite, extensive burns);
• collapse, intestinal fistula, dysentery, vomiting, diarrhea, food poisoning, El Tor cholera and other pathologies associated with severe intoxication;
• dehydration due to severe blood loss, circulatory disorders;
• peritonitis (inflammation of the peritoneum);
• hypotonic and isotonic forms of hypohydration;
• intestinal obstruction;
• plasmapheresis.

Ringer's solution instructions for use

The Ringer-Locke healing solution, the instructions for use of which state that it is intended for hospital conditions, cannot be used independently. In rare exceptions, you can limit yourself only to the supervision of a doctor. The duration of the healing course is up to 5 days. The dosage is calculated by the medical professional based on the patient’s weight. Before injection into the bloodstream, the solution is prepared, and then injections are made by stream, if necessary, or by drip. The drug is used to wash wounds and mucous membranes.

Ringer's solution - contraindications

Like any other medicinal product, Ringer's solution has its contraindications. Do not use after the expiration date and are not recommended for use in case of individual intolerance or hypersensitivity to elements of the drug composition. When taking anabolic steroids, non-steroidal anti-inflammatory drugs and estrogens, you should be careful. Other contraindications when taking the solution intravenously:

• swelling of the brain or lungs;
• hypernatremia;
• hyperchloremia;
• hypovolemia;
• kidney disease, oliguria, anuria;
• taking glucocorticosteroids;
• hormone therapy;
• heart failure (stage of decompensation);
• acidosis.

In combination with cardiac glycosides, Ringer's medicine puts a strain on the heart and blood vessels, and together with angiotensin-converting enzyme inhibitors, diuretics or potassium supplements, it can lead to an increase in plasma potassium concentrations (hyperkalemia). Under close medical supervision and with caution, the drug can be used in the following categories of patients:

• patients with arterial hypertension;
• elderly people;
• patients taking other blood products;
• patients in the postoperative period.

Interaction with other drugs

It is possible to increase sodium retention in the body while taking the following medications: non-steroidal anti-inflammatory drugs, androgens, anabolic hormones, estrogens, corticotropin, mineralocorticoids, vasodilators or ganglion blockers.

When taken with potassium-sparing diuretics, angiotensin-converting enzyme (ACE) inhibitors and potassium supplements, the risk of developing hyperkalemia increases.

It is possible to increase sodium retention in the body while taking the following medications: NSAIDs, androgens, anabolic hormones, estrogens, corticotropin, mineralocorticoids, vasodilators or ganglion blockers.

In combination with cardiac glycosides, the likelihood of their toxic effects increases.

Effect of Ringer's solution

The unique medicine belongs to the salt plasma-substituting agents and contains in isotonic concentrations a combined combination of blood ions: HCO3–, Na+, Cl–, Ca2+, K+. The pharmacological properties of medical fluid include restoring the water-salt balance, eliminating the lack of fluid in the body, which occurs when extracellular fluid accumulates in places of pathology or during dehydration. Ringer's solution reduces the viscosity and sludge of blood, improving its fluidity (rheological properties).

If it is necessary to restore the volume of circulating blood, then take into account that the effect of the solution in the bloodstream will last no more than 40 minutes. The medication is intended only for short-term replenishment of blood volume. By contacting a doctor, you will receive professional advice and will not make mistakes. The specialist knows that to treat severe hypovolemia, the medication can only be prescribed in combination with other colloidal solutions. The high content of chloride ions does not allow the solution to be used for a long time.

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Pharmacological properties

A rehydrating agent, it has a detoxifying effect, stabilizes the water and electrolyte composition of the blood.

When used as a means of replenishing the volume of circulating blood, due to the rapid exit from the bloodstream into the extravasal space, the effect lasts for only 30–40 minutes (and therefore the solution is suitable only for short-term replenishment of the volume of circulating blood).

Side effects of Ringer's solution

If the dosage is incorrect, taken for contraindications, or self-administered, side effects of Ringer's solution can often occur. If you follow all the doctor’s instructions, then, judging by the reviews, the solution is well tolerated by patients. To eliminate the unpleasant conditions that arise, reduce the dose of the drug. The doctor can immediately stop treatment only if an allergic reaction occurs. Later, it is necessary to carry out antiallergic procedures (desensitizing therapy). Among the unwanted reactions of the body to the medication are:

• decreased plasma potassium concentration (hypokalemia);
• allergies, manifested as rashes, hives and itchy skin;
• Excessive amount of water in the body or a particular part of the body (overhydration).

Ringer during pregnancy

Adequate laboratory studies of the effects on the fetus have not been conducted, so Ringer's solution during pregnancy is prescribed only when the expected benefit to the mother's body is higher than the risk to the unborn child. There have been no clinical data on the influence of the components contained in the drug and entering the child’s body along with mother’s milk during lactation. Therefore, during breastfeeding you should refrain from using the solution.

Reviews

There are a lot of positive reviews about Ringer's solution. Droppers with this drug are given to children, pregnant women, and even animals. Some are simply delighted with this product.

Here are some reviews:

• “Girls, Ringer is a wonderful remedy. He was the only one who helped. I suffered for a month. This is now the second day that I have been using it and I am already much better. I advise everyone …"
• “My cat had one paw in the grave, and this solution was the only way to save her…”
• “It was Ringer who helped me. I started to eat at least a little, because before that I hadn’t eaten at all for a week and a half...”

Ringer for children

The use of medication for children is permitted only under the supervision of a doctor and in medical institutions. For each child, the doctor calculates an individual dosage, which is determined depending on body weight and age. You can take the product as inhalation. The generally accepted daily dose is calculated using the formula: from 5 to 10 milliliters per 1 kg. The rate of administration of Ringer for children is 30-60 drops/minute. In a situation with shock dehydration, 20-30 milliliters of medication per kg are administered.

Ringer's solution price

If for any reason the patient cannot take this drug, then the doctor prescribes a drug with a similar mechanism of action. Judging by the reviews, among Ringer's analogues there are such inexpensive solutions as: Disol, Acesol, Trisol. The medicine itself, Ringer, from the group of parenteral electrolytes, is inexpensive in Moscow pharmacies. Available according to prescription. The price of Ringer's solution starts from 30 rubles. You can order the drug from the catalog and buy it in online stores. The cost varies depending on the quantity of goods purchased (milliliters) and the manufacturer.

Conditions for pharmaceutical dispensing and storage

Ringer's solution is sold strictly according to prescription. The use of the drug is permitted only in medical institutions. Store the product at a temperature of 15-25 degrees. Before administration, it is advisable to warm the solution to body temperature.

It is possible to use frozen medication for storage. In this case, special attention is paid to the appearance of the solution: it must be completely transparent. Foreign inclusions (sedimentary particles, flakes), violation of the tightness of the packaging are contraindications to the administration of the product.