Pharmacodynamics and pharmacokinetics
Baneocin is an antimicrobial combination remedy used exclusively for topical (local) use and includes two antibacterial drugs, characterized by their pronounced bactericidal effect .
Neomycin is an aminoglycoside antibiotic bacterial protein synthesis . The activity of this antibacterial agent is manifested against many gram-positive and gram-negative bacterial microorganisms .
Bacitracin belongs to the group of polypeptide antibiotics that inhibit the replication processes of the bacterial cell membrane . The main antibacterial effect of this drug is observed against gram-positive microorganisms representing the genus Staphylococcus and Streptococcus , as well as against some gram-negative bacteria (resistance to bacitracin is very rarely formed).
The synergism (combined action) of these two antibacterial drugs leads to a significant increase in the therapeutic spectrum of action of bacitracin and an increase in its effectiveness against a number of microorganisms , in particular staphylococci .
When using the drug locally, absorption of its active ingredients, as a rule, is not observed (even when applied to damaged skin). However, at the time of therapy, their high concentration is detected in the skin.
This drug is characterized by good tissue tolerance , and therefore its use on large skin areas may cause systemic absorption.
Pharmacological properties and composition of the drug
Baneocin is a combination product that contains two main active ingredients, bacitracin and neomycin, which have an antibacterial effect. In this case, bacitracin inhibits the synthesis of bacterial cell walls, and neomycin prevents the formation of their protein elements. The main auxiliary components of the ointment are white paraffin and lanolin, and corn starch powder. They ensure the most comfortable use of the drug and help preserve its properties throughout the entire shelf life.
Indications for use
The use of Baneocin ointment and Baneocin powder is indicated for the purpose of local therapy of infectious and inflammatory skin diseases that were caused by microorganisms sensitive to the active ingredients of the drug, including:
- of umbilical infection in newborns ;
- prevention of possible infectious complications after surgical ( dermatological ) manipulations, as additional therapy in the postoperative period after episiotomy , cauterization , tissue excision, treatment of weeping wounds , cracks and sutures ;
- treatment of local bacterial skin infections trophic ulcerative lesions of the lower extremities, contagious weeping impetigo , infected eczema , bacterial diaper dermatitis , including bacterial complications caused by Varicella zoster and Herpes simplex .
Price and release forms
Average price online* 330 rub.
Baneocin is produced in two pharmaceutical forms:
- Powder packaged in 10 gram plastic bottles and cream (ointment) packaged in 5 or 20 gram aluminum tubes. One gram of the powder form of Baneocin contains bacitracin zinc - 250 IU, neomycin sulfate - 5000 IU. As an additional substance, sterile corn starch based on 20% magnesium oxide was added to the medicine. Externally, the powder is a white or yellowish powder.
- Baneocin ointment consists of zinc batracin (250 IU) and neomycin sulfate (5000 IU).
The basis of the ointment is lanolin and paraffin. The healing cream has a yellow color and a uniform fatty consistency, as well as a specific light aroma.
How much the drug costs depends on the form of release of the medicine.
Baneocin ointment 5 grams has a price from 160 to 180 rubles, 20 grams from 300 to 360 rubles, powder costs 400-450 rubles.
You can buy Baneocin at any pharmacy without a prescription.
Contraindications
It is prohibited to use any of the dosage forms of the drug when:
- extensive skin lesions (due to the risk of an ototoxic effect manifested by hearing loss );
- personal hypersensitivity to neomycin , bacitracin or other aminoglycosides ;
- severe disorders of renal excretory function (due to renal or heart failure );
- diagnosed pathologies of the cochleo-vestibular system (if systemic absorption of the active ingredients of the drug is possible);
- diseases of the visual organs.
Side effects
Baneocin ointment and Baneocin powder, as a rule, do not lead to any negative effects when used topically on small problem areas of the skin and mucous membranes, which is why the ointment and powder of this drug are recommended for use specifically for the treatment of local infectious diseases .
With prolonged use, allergic manifestations , including dry skin , redness , skin rash / itching . Mostly these phenomena occur similar to contact eczema , in half of the cases they are provoked by cross- allergy to other aminoglycosides and are observed quite rarely.
of systemic negative effects is allowed , in most cases noted in the treatment of extensive skin lesions, when there is a high possibility of absorption of the active ingredients of the drug and the occurrence of its nephrotoxic and ototoxic neuromuscular conduction disorders .
Features of the appointment for infants
Since Baneocin effectively heals wounds after cutting the umbilical cord, it is often prescribed by attending physicians. The effectiveness of the ointment is so high that the wound heals within 4-5 days. In addition, the wounds are washed with a three percent peroxide solution. Sometimes, instead of gel, powder is used, which is poured directly into the navel. Purulent lesions are additionally wiped with dry cotton wool.
Older children can smear the wound if they are bitten, cut, hit, or have a callus. It is necessary to take into account that before breastfeeding you need to wash off any remaining medication from the skin.
Instructions for use of Baneocin (Method and dosage)
Baneocin powder, instructions for use
The drug in powder form is indicated for use 2-4 times a day with a thin layer of it on the affected skin areas.
In the case of treating burns that occupy more than 20% of the patient’s body surface, the powder can be used only once every 24 hours, especially if the patient has reduced renal function (due to the possible absorption of active ingredients into the systemic circulation).
When used topically, the maximum daily dosage of neomycin can be 1 gram, which corresponds to the use of 200 grams of powder per week. A repeated therapeutic course requires reducing the weekly maximum dosage by half (up to 100 grams).
Baneocin ointment, instructions for use
The drug in the form of an ointment is allowed for use 2-3 times a day, for which Baneocin ointment is applied in a thin layer to the affected areas of the skin. You can practice applying ointment under the bandage .
It is possible to use the ointment in the postoperative period as an additional therapeutic agent. Application of the drug directly to bandages is preferable in the case of local treatment of infected wounds and cavities (including surgical scars healed by secondary intention and bacterial infections of the external auditory canal without damage to the eardrum ).
How to treat an umbilical wound
The powder is approved for use in children during the neonatal period. The drug is used only according to indications and in agreement with the pediatrician. In most cases, it is enough to use less serious antibacterial drugs to heal the navel.
The use of Baneocin for treatment is advisable:
- if the wound does not heal for a long time;
- the navel becomes wet, crusts form;
- the appearance of an unpleasant odor;
- the presence of purulent masses in the wound during healing;
- general poor condition of the baby, indicating an inflammatory process in the navel.
The pediatrician explains the procedure for treating with an antibacterial drug. Wound powder Baneocin is approved for healing the navel in the first days of a child’s life.
Standard rules for purulent wounds:
- Wash your hands, remove the diaper.
- Wash your stomach with boiled water at room temperature. The use of baby soap is allowed.
- Treat the navel with hydrogen peroxide. Blot off excess.
- Sprinkle the powder on the affected area.
- If possible, leave the child without a diaper or clothes. Allow the skin to absorb the healing agent.
The number of wound treatments with Baneocin is prescribed by the doctor. The standard recommendation in the instructions is 2–5 times a day. The duration of treatment should not exceed 7 days.
Interaction
If systemic absorption of the active ingredients of the drug is possible, parallel use of aminoglycosides or cephalosporins increases the risk of nephrotoxic phenomena .
The combined administration of Baneocin with Furosemide or Ethacrynic acid increases the possibility of nephrotoxic and ototoxic reactions.
With observed systemic absorption, the combined use of Baneocin with muscle relaxants , anesthetics and opioid analgesics can lead to the development of neuromuscular blockade .
cases of incompatibility of neomycin and bacitracin with other medications.
special instructions
In the case of using dosages of Baneocin that significantly exceed the recommended ones, due to the possible absorption of its active ingredients, it is necessary to pay attention to negative symptoms that may indicate ototoxic or nephrotoxic reactions.
Due to the increased risk of toxic effects in patients with observed / kidney pathologies, urine and blood together with audiometric studies , both before the start of therapy and during treatment .
If during therapy the possibility of absorption of the active ingredients of the drug is allowed (in case of extensive skin damage), then there is a need to control the possible formation of symptoms of neuromuscular blockade , especially in patients with myasthenia , other neuromuscular pathologies , as well as acidosis . If neuromuscular blockade it is recommended to prescribe neostigmine calcium supplements .
Long-term use of Baneocin requires monitoring for a possible excessive increase in the number of resistant microorganisms , sometimes with the need to prescribe appropriate therapy.
Long-term use of Baneocin for the treatment of children with liver / kidney , as well as the use of the drug to treat large areas of skin, must be previously agreed with a doctor.
If superinfection or allergic manifestations , Baneocin therapy should be discontinued.
Proper treatment for wounds and burns
Much depends on how correctly we are able to navigate a given situation. This is especially true for providing first aid to yourself and your loved ones. Therefore, if burns or wounds occur, you should not hope that everything will go away on its own. An open wound is the main route for pathogenic bacteria to enter the body.
In the event of burns, the first step is to eliminate the damaging agent (cool the area in case of a thermal burn or remove the substance that is the source of a chemical burn from the surface of the skin). After this, if possible, it is necessary to clean the skin of impurities, and then treat the surface around the wound with an antiseptic and apply a drug to the wound that draws out pus, prevents the development of bacterial infection and promotes speedy healing.
Using oils or puncturing blisters is strictly prohibited.
A bandage is applied to the damaged surface as needed.
The wound surface is treated in a similar way.
In all cases, difficult situations are a reason to immediately seek specialized medical help.
Analogs
Level 4 ATC code matches:
Bacitracin
Fucidin
Bactroban
Fusiderm
Sintomycin
Analogues of Baneocin ointment and powder are represented by medicinal products used for topical use (ointments, aerosols, creams, solutions):
- Bactroban;
- Altargo;
- Gentamicin;
- Chitosan-Ghent;
- Levomycetin;
- Tyrosur;
- Sintomycin;
- Fusiderm;
- Neomycin;
- Supirocin;
- Fusicutane.
Baneocin for children
The use of the drug Baneocin is allowed for the treatment of children only after prior consultation with a pediatrician. Most often, I prescribe this powder and ointment for children for acne ( boils , carbuncles ), paronychia , hidradenitis , burns , and even for the treatment of chickenpox (chickenpox).
Reviews about Baneocin
Reviews of Baneocin ointment, as well as reviews of the powder of this remedy, are overwhelmingly positive. The use of this drug, both for the treatment of adult patients and for the treatment of children, really leads to rapid and high-quality healing of infected wound skin surfaces and almost never causes the development of any side effects.
Also, favorable reviews of Baneocin are left by young mothers who use the powder of this remedy to prevent possible umbilical infection in their newborn babies.
Baneocin receives a somewhat less positive assessment when used for acne and in the case of treating large affected skin areas, but in any case, the effectiveness of the drug remains high.
Reviews from consumers and experts
The number of opinions that exist regarding Baneocin varies. However, most of them are positive. Consumers and specialists who have experience using the drug return to it again and again. This is facilitated by the low number of contraindications, its high efficiency and safety. In addition, the drug is affordable and easy to use.
The amount of time spent treating wounds and burns largely depends on the correct medical care provided and the quality of the drugs used. Over many years, Baneocin has proven its effectiveness and safety in this area. The possibility of using the drug in children and adults makes it an indispensable component of the home first aid kit of every person who cares about their health.
Features of the use of the drug Baneocin for wounds and burns
Baneocin price, where to buy
The ointment and powder of the drug are approximately in the same price category. The price of Baneocin ointment is about 350-400 rubles, the price of Baneocin powder ranges from 360-420 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Baneocin ointment 20gMerck KG&Co
RUB 358 order - Baneocin powder for external use. approx. 10g Pharmazoitische Fabrik Montavit GmbH
380 rub. order
- Baneocin ointment for external use. approx. tube 5gP&G Health Austria GmbH & Co/ Sandoz GmbH
RUB 207 order
Pharmacy Dialogue
- Baneocin ointment (tube 5g)Merck KgaA
RUB 253 order
- Baneocin ointment (tube 20g)Merck KgaA
455 rub. order
- Baneocin (por. 10g) Montavit Fabrik
422 rub. order
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Pharmacy24
- Baneocin 10 g powder Pharmaceuticals Factory Montavit GesmbH/Sandoz GmbH, Austria/Austria
103 UAH.order - Baneocin 20 g ointment Merck KgaA & Co. Werk Spittal/Sandoz GmbH-TechOps, Austria/Austria
104 UAH order
PaniPharmacy
- Baneocin ointment Baneocin ointment 20g tube Austria, Sandoz
109 UAH order
- Baneocin Baneocin powder for external use 10g No. 1 Austria, Sandoz
119 UAH order
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