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Manufacturers: Borshchagovsky Chemical and Pharmaceutical Plant
Active ingredients
- Belladonna alkaloids
Disease class
- Not indicated. See instructions
Clinical and pharmacological group
- Antispasmodics with myotropic and m-anticholinergic effects
Pharmacological action
- Antispasmodic
Pharmacological group
- Myotropic antispasmodics in combinations
Pharmacodynamics and pharmacokinetics
Antispasmodic as well as hyposecretory effects (reduced bile secretion, pancreatic secretion, gastric, bronchial, sweat and salivary glands) are caused by m-anticholinergics from belladonna extract, while the antacid effect (neutralization of hydrochloric acid in the gastric juice) is due to the active substance of Becarbon - sodium bicarbonate.
In addition, it increases the excretion of sodium and chlorine, increases osmotic diuresis and shifts the reaction of bronchial mucus to the alkaline side, makes coughing sputum less viscous and stimulates expectoration.
Side effects
Becarbon tablets can affect the human body in a negative way, and thereby provoke the following types of side effects:
- digestive disorders - constipation and loss of appetite;
- changes in the distribution of fluid in the body - dry mucous membranes (especially in the mouth), urinary retention, feeling of thirst;
- change in perception - loss of taste and, as a result, lack of appetite, as well as a change in visual perception;
- changes in the contractile functions of the myocardium – tachycardia;
- changes in the functioning of the central nervous system and autonomic nervous system - drowsiness, dizziness, agitation.
In case of overdose
If the recommended dosages are exceeded, Becarbon tablets can cause belladonna poisoning, which is expressed by the following symptoms:
- nausea and repeated vomiting;
- idiosyncrasy;
- tachycardia or tachyarrhythmia;
- myocardial ischemia;
- hyperthermia due to a sharp decrease in the functioning of the sweat glands;
- hives;
- impotence;
- secretion of breast milk.
If signs of these conditions appear, it is recommended to immediately stop taking the pills and consult a doctor.
Contraindications
Becarbon tablets have strict and relative contraindications. Thus, it is not recommended to use them if you have the following diseases:
- confirmed or suspected glaucoma;
- prostate adenoma, accompanied by urinary retention;
- constipation caused by intestinal atony;
- stenosis of the digestive tract;
- atherosclerosis;
- heart pathology in the stage of decompensation;
- myasthenia gravis;
- tachyarrhythmia;
- lactation (GW);
- intolerance to the components of the drug.
Bekarbon is prescribed with increased caution to patients with diseases of the cardiovascular system (coronary heart disease, heart failure and hypertension), reflux esophagia, hyperfunction of the thyroid gland and polyneuropathy. It is not recommended to use the medicine for course therapy for persons who have been diagnosed with cholelithiasis or nephrolithiasis.
Becarbon can affect the ability to concentrate and the ability to drive vehicles, therefore, while taking them, it is not recommended to drive vehicles or engage in activities that require quick reaction.
During pregnancy
The use of the drug for the treatment of functional digestive disorders in pregnant women is possible only for exceptional indications and in the absence of risk to the fetus. During lactation, the use of Becarbon is strictly prohibited.
Interaction
When using Becarbon:
- With Amantadine , tricyclic antidepressants , antiarrhythmic anticholinergic drugs, including Quinidine , Nefopam , Glutetimide , the anticholinergic effect of Becarbon tablets is enhanced.
- With opioid analgesics and drugs that depress the central nervous system (including phenothiazines ), dangerous central nervous system inhibition develops.
- With butyrophenones and Haloperidol , as well as organic nitrates, intraocular pressure may increase.
- With corticosteroids (when used systemically), the effect of corticosteroids is reduced and intraocular pressure may increase.
- Becarbon reduces the effects of Pilocarpine in the treatment of glaucoma .
- Combination with m-anticholinergics causes increased anticholinergic effects.
- Use with Furosemide may cause orthostatic hypotension .
- Reserpine , MAO inhibitors , guanethidines , antacids, vitamin C , Attapulgite - reduce the effects of Becarbon.
- It is recommended to adjust the dosage of Levodopa , as its systemic concentrations may decrease.
- With some antihistamines , for example, with Meclizine an increase in antihistamine effect is observed.
- With β-adrenergic receptor blockers, their effects may be reduced.
- With hormonal contraceptives - decreased contraceptive effect.
- With drugs that include non-selective inhibitors of neuronal reuptake of monoamine mediators , an increase in the sedative effect of both drugs is observed.
- Non-steroidal anti-inflammatory drugs such as Griseofulvin , Digitoxin , Doxycycline , Metoclopramide , Metronidazole in combination with Becarbon cause a decrease in the effects of these drugs.
- With sulfonamides - the risk of kidney damage increases.
- With Indapamide , Nizatidine - potentiation of their effects.
- With Ketoconazole, the pH of the gastric juice increases, the absorption of Ketoconazole decreases, therefore Becarbon is recommended to be taken 2 hours after taking Ketoconazole tablets.
- Potassium chloride may cause damage to the gastrointestinal mucosa.
- The effects of anticholinergic drugs are antagonistic to the effect of Domperidone on gastrointestinal activity.
- Sodium bicarbonate as a component of Becarbon can increase the excretion of Lithium , thereby reducing its concentration in the blood plasma.
Instructions for use
The list of indications, contraindications, pharmacological properties and a detailed mechanism of action of Becarbon on the digestive system is described in the instructions. The manufacturer gives an example of a standard dosage regimen and dosage regimen for the drug. If there are special instructions, these instructions can be adjusted by your doctor. Additionally, the manufacturer provides recommendations for storing the medication, describes the features of its drug interactions with other pharmaceuticals, and explains the principle of use for certain groups of patients.
pharmachologic effect
Along with the ability to suppress the synthesis of gastric secretions, this medicine can reduce the tone of the gallbladder and its ducts, increase intraocular pressure and provoke paralysis of accommodation.
The drug can also cause disturbances in heart rhythm, which is due to the action of its constituent components. In this regard, when using Becarbon, you must strictly follow the instructions for using the drug.
Release form and composition of the drug
Becarbon is a combination drug with herbal and synthetic components that affects peripheral mediator processes in the intestines and the body as a whole (especially if you take a large dose of the drug).
The drug contains belladonna (belladonna) extract, which helps reduce spasms, and sodium bicarbonate, a substance with antacid properties that reduces the aggressive effect of hydrochloric acid on the gastric mucosa and increases osmotic diuresis.
One tablet contains:
- 0.01 g belladonna extract;
- 0.3 g sodium bicarbonate;
- starch;
- talc.
Externally, the drug looks like classic flat-cylindrical tablets with a score and a chamfer, colored yellowish-brown. Brown, gray and/or black inclusions are visible on the surface and fracture of the tablets. The medicine is packaged in paper packages with a layer of polymer film, 10 pieces each.
Indications for use
Becarbon is used for functional disorders of the gastrointestinal tract, expressed by symptoms such as intestinal colic and heartburn.
They appear in the presence of various gastrointestinal diseases or errors in nutrition, namely:
- with hyperacid gastritis;
- dyspepsia;
- increased acidity of gastric juice;
- intestinal spasms.
Mode of application
Becarbon tablets are intended for oral administration. It is recommended to drink them 20-30 minutes before eating, 1 piece per meal. The frequency of administration per day is no more than three. The dosage can be increased according to indications and only with the approval of a doctor. The maximum permissible dose per dose is 5 tablets.
The duration of drug therapy is determined by the severity of symptoms and the depth of damage to the gastrointestinal tract, tolerability of the drug and other factors, including the effectiveness of therapy on the first day of treatment.
Drug interactions
Due to the fact that Becarbon tablets contain two active components acting in several directions, the list of possible interactions with other drugs remains quite wide. Belladonna extract has the greatest interaction activity, which affects the absorption of certain compounds and drugs:
reduces or completely stops the effect of anticholinergics and anticholinesterics;- potentiates the effect of MAO inhibitors, which may result in arrhythmia;
- potentiates the effect of cardiac glycosides;
- enhances the effect of clonidine and barbiturates;
- potentiates the effect of tranquilizers;
- increases the medicinal activity of antihistamines.
Sodium bicarbonate may reduce the effectiveness of some medications that require an acidic environment for absorption.
Becarbon price, where to buy
On average, a package of Becarbon No. 6 tablets costs 40 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
ZdravCity
- Becarbon tab.
n6 JSC Tatkhimfarmpreparaty 33 rub. order
Pharmacy Dialogue
- Becarbon (tab. No. 6) TCPP
37 RUR order
show more
Pharmacy24
- Becarbon No. 20 tablets TOV "Agrofarm", Ukraine
13 UAH. order
special instructions
Impact on the ability to drive a car and operate machinery
The manufacturer of the drug recommends taking precautions when driving vehicles and interacting with complex mechanisms. During Becarbon therapy, activities that require concentration and high speed of psychomotor reactions should be avoided.
Pregnancy and lactation period
The list of contraindications for the use of Becarbon contains no mention of pregnancy and the lactation period. Pregnant and lactating women should take the drug with the permission of a doctor.
Application in pediatric practice
Becarbon is not intended for use in pediatric practice.
For liver disorders
Hepatic pathologies are not noted by the manufacturer in the list of contraindications. Becarbon in the presence of liver dysfunction is taken according to the standard regimen.
For kidney problems
Renal dysfunction is not a reason to prohibit taking the drug. If kidney function is impaired, Becarbon is taken according to the standard regimen.
Conditions for dispensing from pharmacies
You can buy Becarbon at pharmacies without a prescription.
Contraindications
The use of Becarbon is contraindicated in children under 12 years of age, with angle-closure glaucoma, prostatic hypertrophy, intestinal atony, atherosclerosis, myasthenia gravis, as well as in cases of patient hypersensitivity to any components of the drug, tachyarrhythmia, and during breastfeeding.
Becarbon is prescribed with caution in cases of hyperthyroidism, chronic heart failure, hypertension, coronary heart disease, polyneuropathy and reflux esophagitis.
Overdose and its manifestations
If you take the drug for longer than the recommended period, or exceed the daily dose, overdose symptoms may appear, which manifest themselves in the form of increased side effects. Many people experience the following symptoms:
- headache;
- convulsions;
- irritability;
- sleep disturbance;
- increased heart rate;
- nausea and vomiting.
To get rid of these symptoms, you need to rinse the stomach, adjust the water-electrolyte balance and take activated charcoal .
Reviews
Becarbon is one of the few products that has a lot of reviews. This is due to the fact that several generations of people are familiar with its name and the effect it produces (tablets of this brand have been produced for several decades).
Along with the positive ratings given to the tablets for their excellent ability to relieve intestinal spasms quickly and for a long time, consumers talk about a high risk of side effects (at least 40% of respondents mention their occurrence). However, the medicine remains popular, especially among older and older consumers.
Detailed reviews about Becarbon tablets can be read at the end of this article. If you yourself have had experience using this drug, share your impressions with other readers.
Directions for use and dosage
the method of using Becarbon and its dosage depending on the patient’s condition and his tests. Most often, the drug is taken one tablet 2-3 times a day, about half an hour before meals . The maximum daily dose is up to 5 tablets. They should be swallowed and washed down with water; they should not be chewed.
Remember that the drug has only a short-term and symptomatic effect; accordingly, the duration of treatment is controlled by the attending physician. If the symptoms of the disease do not go away within 3-5 days, the use of Becarbon will be reconsidered in the future.